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The map label for this gene is htrB [C]

Identifier: 54295780

GI number: 54295780

Start: 3275828

End: 3276664

Strand: Reverse

Name: htrB [C]

Synonym: lpl2870

Alternate gene names: 54295780

Gene position: 3276664-3275828 (Counterclockwise)

Preceding gene: 54295781

Following gene: 54295775

Centisome position: 97.94

GC content: 36.2

Gene sequence:

>837_bases
ATGGCTAATCCTTATTTATCTAAACTCCGAGTCACTTTTGCAGGTCTTCTTTTTTATTGGTTTTTACCTATTCGCAAACA
AATTGTATTAAATAACATAGATATTGTTTTTAAAAATACAGCAACTTCTGCTGAGAAAATAAGATTGGCAAAGGCTTTTT
ATTCCCATGTAGCCTCTACTTTAAAAGAAATGTTTTTGATGAATAGGCCAAGTTCTAAAAAATTGAATCAACAAGTGGAA
ATCCACGGAGTAGAGCATTTGCAAAGAGCAATTGACCAGAAGAAGGGAGTTCTTTTATTAACAGGTCATTTAGGGAGTTG
GGAATTAATATCAGTATTAGGTTTTTCACGCTTAATATCTCAATATGGACAAATAAATGTTATCAGGCGCCCTATTCGCA
TGAAATGGTTAGAAACCTGGCTATTTAAAAGAATTGCACATCATGGGTTAGGCGTTATCAATAGCATCGGTGCTCCGAAA
AAAATAAACCAAGCCATAAAGAATAAAGAGTTGGTGCTTTTTGCTATGGATCAACATGCCCAACTAGAAAATAAGTCCGG
GATCGCTGTAGAGTTTTTTGGTATTAAGGCTGGAACATACCGAAGTTTGGCTTTTTTTGCCCATAAACATCAAGCGCCAG
TTGTTCCGGTGTCCAGTTATAGGCAACACAACGGCAAGCACATTATGAAATTTTACCCAGAGATAGAATGGGAATTTCAT
GCGGTTAAAGAACAAGCTATCTATCAAAACACTCTTCGCTATAATCAAACGCTTGAACAATTAATTTTAGAGCATCCAGA
GCAATGGTGGTGGGTTCATAGACGATGGAAATTATAG

Upstream 100 bases:

>100_bases
CTCTTATAGAAAACACTCAACTTTATAATAAAAGATTGGAAGAGATGTTATTGCTTTATCCTGAACAATGGTTATGGTCA
TACAAACGCTGGAAAAAATA

Downstream 100 bases:

>100_bases
ATAAATAGATTTTTAAATTAGCCACCCTGTTTATTTCATAAAAAGGGGGTGCGATATTTAATTATCAATAGGCGTTTCTC
TAGAGATTGGAGCAGTCGTA

Product: hypothetical protein

Products: KDO2-(lauroyl)-lipid IVA [C]

Alternate protein names: Lipid A Biosynthesis Lauroyl Acyltransferase; Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase; Lauroyl/Myristoyl Acyltransferase; Lipid A Biosynthesis-Lipid IVA Acyltransferase; Lipid A Biosynthesis Lauroyl/Myristoyl Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase Superfamily; Lipid A Biosynthesis Lauroyl Acyltransferase Subfamily; Acyltransferase HtrB Family; Lipd A Biosynthesis Related Exported Protein; Lipid A Lauroyl Acyltransferase; Lipid A Biosynthesis Lauroyl; Dodecanoyltransferase LpxL

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MANPYLSKLRVTFAGLLFYWFLPIRKQIVLNNIDIVFKNTATSAEKIRLAKAFYSHVASTLKEMFLMNRPSSKKLNQQVE
IHGVEHLQRAIDQKKGVLLLTGHLGSWELISVLGFSRLISQYGQINVIRRPIRMKWLETWLFKRIAHHGLGVINSIGAPK
KINQAIKNKELVLFAMDQHAQLENKSGIAVEFFGIKAGTYRSLAFFAHKHQAPVVPVSSYRQHNGKHIMKFYPEIEWEFH
AVKEQAIYQNTLRYNQTLEQLILEHPEQWWWVHRRWKL

Sequences:

>Translated_278_residues
MANPYLSKLRVTFAGLLFYWFLPIRKQIVLNNIDIVFKNTATSAEKIRLAKAFYSHVASTLKEMFLMNRPSSKKLNQQVE
IHGVEHLQRAIDQKKGVLLLTGHLGSWELISVLGFSRLISQYGQINVIRRPIRMKWLETWLFKRIAHHGLGVINSIGAPK
KINQAIKNKELVLFAMDQHAQLENKSGIAVEFFGIKAGTYRSLAFFAHKHQAPVVPVSSYRQHNGKHIMKFYPEIEWEFH
AVKEQAIYQNTLRYNQTLEQLILEHPEQWWWVHRRWKL
>Mature_277_residues
ANPYLSKLRVTFAGLLFYWFLPIRKQIVLNNIDIVFKNTATSAEKIRLAKAFYSHVASTLKEMFLMNRPSSKKLNQQVEI
HGVEHLQRAIDQKKGVLLLTGHLGSWELISVLGFSRLISQYGQINVIRRPIRMKWLETWLFKRIAHHGLGVINSIGAPKK
INQAIKNKELVLFAMDQHAQLENKSGIAVEFFGIKAGTYRSLAFFAHKHQAPVVPVSSYRQHNGKHIMKFYPEIEWEFHA
VKEQAIYQNTLRYNQTLEQLILEHPEQWWWVHRRWKL

Specific function: Acylates The Intermediate (Kdo)2-Lipid IVa To Form (Kdo)2-(Lauroyl)-Lipid IVa. Has 10 Fold Selectivity For Lauroyl- Acp Over Myristoyl-Acp. [C]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787292, Length=263, Percent_Identity=26.2357414448669, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.- [C]

Molecular weight: Translated: 32549; Mature: 32417

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANPYLSKLRVTFAGLLFYWFLPIRKQIVLNNIDIVFKNTATSAEKIRLAKAFYSHVAST
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
LKEMFLMNRPSSKKLNQQVEIHGVEHLQRAIDQKKGVLLLTGHLGSWELISVLGFSRLIS
HHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
QYGQINVIRRPIRMKWLETWLFKRIAHHGLGVINSIGAPKKINQAIKNKELVLFAMDQHA
HCCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHCCCCEEEEEECCCC
QLENKSGIAVEFFGIKAGTYRSLAFFAHKHQAPVVPVSSYRQHNGKHIMKFYPEIEWEFH
CCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEECCCCCCHHH
AVKEQAIYQNTLRYNQTLEQLILEHPEQWWWVHRRWKL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEHHHCCCC
>Mature Secondary Structure 
ANPYLSKLRVTFAGLLFYWFLPIRKQIVLNNIDIVFKNTATSAEKIRLAKAFYSHVAST
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
LKEMFLMNRPSSKKLNQQVEIHGVEHLQRAIDQKKGVLLLTGHLGSWELISVLGFSRLIS
HHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
QYGQINVIRRPIRMKWLETWLFKRIAHHGLGVINSIGAPKKINQAIKNKELVLFAMDQHA
HCCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHCCCCEEEEEECCCC
QLENKSGIAVEFFGIKAGTYRSLAFFAHKHQAPVVPVSSYRQHNGKHIMKFYPEIEWEFH
CCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEECCCCCCHHH
AVKEQAIYQNTLRYNQTLEQLILEHPEQWWWVHRRWKL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; lauroyl-ACP [C]

Specific reaction: KDO2-lipid IVA + lauroyl-ACP = KDO2-(lauroyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA