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The map label for this gene is apaH [H]

Identifier: 54295763

GI number: 54295763

Start: 3257326

End: 3258156

Strand: Reverse

Name: apaH [H]

Synonym: lpl2853

Alternate gene names: 54295763

Gene position: 3258156-3257326 (Counterclockwise)

Preceding gene: 54295764

Following gene: 54295762

Centisome position: 97.38

GC content: 45.25

Gene sequence:

>831_bases
GTGCCTGATTATGCAATAGGGGATATACAAGGTTGTTATGATCCTTTACAACGGTTGCTTGAGCTAATTGATTTTAACGA
GAAGGACGATTGCTTGTGGTTTGTTGGGGACTTGGTAAACCGCGGTCCTGATTCATTGGCTGTATTACGGTTTATTTATT
CCTTGCCTGTGAAACCCAAAATAACCTTGGGTAATCATGATTTGCATTTATTAGGCTTATTATTCGGCGGACAACCCTGG
AAAGGACATGATGATACACTTGAAGAGGTGATGCTGGCTGATGATGGAGAGGAGCTGGGGCATTGGTTGCGCAAGCAATC
CCTTCTTTGCAGGTCATCTGAGTTAAACATAGTTATGTGTCATGCAGGTATCGCGCCTTTATGGGATTTATCGAAGGCCG
TGGGCTTGGCTAATGAATTGGAAGCGGTGCTTTCAGGCGATTCATATCACGAATTTTTCGCCCAAATGTACGGCAATAAG
CCGGATATTTGGTCAGATGATTTGGTTGGGCTGGATAGATTACGAGTCATTACCAATTATTTTACCCGGATGCGCTATTG
TGATGCCCATGGACGATTAGATTTGGGTTATAAGGGGACTTTATCCAAAGCCCCCAATCATCTGTATCCCTGGTTTGAAG
TGCCATGCCGAAAAGAAATTGAAATGGATATCGTTTTTGGTCATTGGGCGGCACTCATGGGGCGAAGTTCTCATCCGCGG
ATTCATGCGATAGATACCGGATGTCTTTGGGGTGGGCAATTAACGGCATTACGCCTGCAGGACAGGCAACGCTTTTCGGT
ACCCGGGTATGGGGTTAGTCGTTTTGAATAA

Upstream 100 bases:

>100_bases
AGTGCGATTGCAATAGCGGCTTTGCAGCGATTGGCAGCCAATGGCCAATGGCAGAATATTGAGCAGGATATGTCCCAATT
GACGCTTGGAGCAAAACGCG

Downstream 100 bases:

>100_bases
CCTTGGTGGATAGACATTTTTATAAACACAGGCGATAACAACGGTGAAATTTTTAAATAAAAGCACAGCATTGTTACCGG
TAATTATTTTATCGGGCCTG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MPDYAIGDIQGCYDPLQRLLELIDFNEKDDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPKITLGNHDLHLLGLLFGGQPW
KGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMCHAGIAPLWDLSKAVGLANELEAVLSGDSYHEFFAQMYGNK
PDIWSDDLVGLDRLRVITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGRSSHPR
IHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE

Sequences:

>Translated_276_residues
MPDYAIGDIQGCYDPLQRLLELIDFNEKDDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPKITLGNHDLHLLGLLFGGQPW
KGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMCHAGIAPLWDLSKAVGLANELEAVLSGDSYHEFFAQMYGNK
PDIWSDDLVGLDRLRVITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGRSSHPR
IHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE
>Mature_275_residues
PDYAIGDIQGCYDPLQRLLELIDFNEKDDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPKITLGNHDLHLLGLLFGGQPWK
GHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMCHAGIAPLWDLSKAVGLANELEAVLSGDSYHEFFAQMYGNKP
DIWSDDLVGLDRLRVITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGRSSHPRI
HAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=268, Percent_Identity=49.6268656716418, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31363; Mature: 31232

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDYAIGDIQGCYDPLQRLLELIDFNEKDDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPK
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHCCCCHHHHHHHHHHCCCCCE
ITLGNHDLHLLGLLFGGQPWKGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMC
EEECCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEE
HAGIAPLWDLSKAVGLANELEAVLSGDSYHEFFAQMYGNKPDIWSDDLVGLDRLRVITNY
ECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
FTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGRSSHPR
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCE
IHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE
EEEEECCEEECCCEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDYAIGDIQGCYDPLQRLLELIDFNEKDDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPK
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHCCCCHHHHHHHHHHCCCCCE
ITLGNHDLHLLGLLFGGQPWKGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMC
EEECCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEE
HAGIAPLWDLSKAVGLANELEAVLSGDSYHEFFAQMYGNKPDIWSDDLVGLDRLRVITNY
ECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
FTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGRSSHPR
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCE
IHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE
EEEEECCEEECCCEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA