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The map label for this gene is ykoW [H]

Identifier: 54295494

GI number: 54295494

Start: 2948560

End: 2949675

Strand: Direct

Name: ykoW [H]

Synonym: lpl2581

Alternate gene names: 54295494

Gene position: 2948560-2949675 (Clockwise)

Preceding gene: 54295492

Following gene: 54295495

Centisome position: 88.13

GC content: 37.81

Gene sequence:

>1116_bases
ATGTCATTACTAAAGAAAACAAGAGAGCAGGATTACTCAATCCTGGTTACCACTCAAGACCAGCAAAGAAAGCGCCATTT
ACTTAATGTTATTTCCATAGAGCTTTTAATTTTGGGTCTTTTGCTGATAATAACAAACATTTGCCTGTTAAGAGCCTGGC
TTATAATCAGTATGTTAATCGTGGGCATGTCCATCTTGCTCGGAAATTTAATCTTAATCAAAAAAAACTTCAATCTGACC
TTGAGTGGGCACATTTTGAATATTCTTGTGTTGTCTATCATCATTGGAGGCAATCTCATCGTTGGAAAAACTACCATGTC
TTACCTGGGATGGTTCTATGTTTCTCCAATCGTTGCTTTTGCTACACTTGGATTAACCGGCTTAGTCGTCTATGGCCTGC
TGGCGATTGGGGCAATGTTTCTTTTTGTGTTCGAATTCTACATTCCCATCTATTCCATTTCTCAGGAATATGTATTTTTT
CTGGATAATACCAACCACCTGTTTATTTTTGCCCTTATTTTCACTGTCCTTTATCATTTTCTGGTTCAAAACTTACAATA
TGAATTGCTGTTAAAAGAGCAAAATTACCTGCTCATTGCCGATAAAGAAAAGTTCCATTACCTTTCGCATCACGACTCAC
TAACCAACTTACCCAACCGCTCCTACTTTCATGCTCATCTTCAGACCCTATTAGAGAATACTGACACTACAAAGGAAGCC
ATTACTCTTTATTTTATGGATTTGGATAAATTCAAGCCCATCAACGACGAATACGGTCATGAGTTCGGTGATCAGCTTTT
ACTTTTAACCAGCAAGCGTTTGCAATCCTGCTTTAGGAAAAATGATTTTATAGCCCGACTGGGAGGAGATGAATTTACGG
CAATTATCGTTCATAAACCCCTTGATCACATTGCTGAGGCTCTAACTCTTAGAATTGAACAGGAATTTGAACAACCTTTT
GTCATAAATGGCCAGACCATTCATTGCACCATAAGCGTTGGGATAGCCAATTACCCGCGCAATGCAAAAAATGCGGAAGA
TTTGTTAAAATGGGCTGATAAAGCGATGTATGATAATAAAAGGAAAAAATATAAAACGCTTAAGCAAACCTCTTAA

Upstream 100 bases:

>100_bases
AACCTCAACGAGAGCAGTGTGGCTGTTTTTTAATCTATAATTGAATTAATAAAGGAAATTAGCCCCATTGATTACCGGCC
AATCCGATTGAGGTAGGTGA

Downstream 100 bases:

>100_bases
CCAACATTCCTAATTTAATCAGTATGATTGGGCCTTCATTTTATAAAGCACAGGATGCAGCAATCTGACATTCACTTGAC
AATTAACTTTTACAACTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSLLKKTREQDYSILVTTQDQQRKRHLLNVISIELLILGLLLIITNICLLRAWLIISMLIVGMSILLGNLILIKKNFNLT
LSGHILNILVLSIIIGGNLIVGKTTMSYLGWFYVSPIVAFATLGLTGLVVYGLLAIGAMFLFVFEFYIPIYSISQEYVFF
LDNTNHLFIFALIFTVLYHFLVQNLQYELLLKEQNYLLIADKEKFHYLSHHDSLTNLPNRSYFHAHLQTLLENTDTTKEA
ITLYFMDLDKFKPINDEYGHEFGDQLLLLTSKRLQSCFRKNDFIARLGGDEFTAIIVHKPLDHIAEALTLRIEQEFEQPF
VINGQTIHCTISVGIANYPRNAKNAEDLLKWADKAMYDNKRKKYKTLKQTS

Sequences:

>Translated_371_residues
MSLLKKTREQDYSILVTTQDQQRKRHLLNVISIELLILGLLLIITNICLLRAWLIISMLIVGMSILLGNLILIKKNFNLT
LSGHILNILVLSIIIGGNLIVGKTTMSYLGWFYVSPIVAFATLGLTGLVVYGLLAIGAMFLFVFEFYIPIYSISQEYVFF
LDNTNHLFIFALIFTVLYHFLVQNLQYELLLKEQNYLLIADKEKFHYLSHHDSLTNLPNRSYFHAHLQTLLENTDTTKEA
ITLYFMDLDKFKPINDEYGHEFGDQLLLLTSKRLQSCFRKNDFIARLGGDEFTAIIVHKPLDHIAEALTLRIEQEFEQPF
VINGQTIHCTISVGIANYPRNAKNAEDLLKWADKAMYDNKRKKYKTLKQTS
>Mature_370_residues
SLLKKTREQDYSILVTTQDQQRKRHLLNVISIELLILGLLLIITNICLLRAWLIISMLIVGMSILLGNLILIKKNFNLTL
SGHILNILVLSIIIGGNLIVGKTTMSYLGWFYVSPIVAFATLGLTGLVVYGLLAIGAMFLFVFEFYIPIYSISQEYVFFL
DNTNHLFIFALIFTVLYHFLVQNLQYELLLKEQNYLLIADKEKFHYLSHHDSLTNLPNRSYFHAHLQTLLENTDTTKEAI
TLYFMDLDKFKPINDEYGHEFGDQLLLLTSKRLQSCFRKNDFIARLGGDEFTAIIVHKPLDHIAEALTLRIEQEFEQPFV
INGQTIHCTISVGIANYPRNAKNAEDLLKWADKAMYDNKRKKYKTLKQTS

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=159, Percent_Identity=35.2201257861635, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786584, Length=194, Percent_Identity=29.3814432989691, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788381, Length=158, Percent_Identity=33.5443037974684, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081977, Length=191, Percent_Identity=34.5549738219895, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787262, Length=159, Percent_Identity=32.0754716981132, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788956, Length=199, Percent_Identity=33.6683417085427, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081881, Length=162, Percent_Identity=32.0987654320988, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=30.3571428571429, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787802, Length=166, Percent_Identity=31.3253012048193, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=28.4810126582279, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081974, Length=152, Percent_Identity=32.8947368421053, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788085, Length=160, Percent_Identity=29.375, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787816, Length=157, Percent_Identity=32.484076433121, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 42763; Mature: 42632

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLKKTREQDYSILVTTQDQQRKRHLLNVISIELLILGLLLIITNICLLRAWLIISMLI
CCHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGMSILLGNLILIKKNFNLTLSGHILNILVLSIIIGGNLIVGKTTMSYLGWFYVSPIVAF
HHHHHHHCCEEEEEECCCEEEHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHH
ATLGLTGLVVYGLLAIGAMFLFVFEFYIPIYSISQEYVFFLDNTNHLFIFALIFTVLYHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LVQNLQYELLLKEQNYLLIADKEKFHYLSHHDSLTNLPNRSYFHAHLQTLLENTDTTKEA
HHHCCCEEEEEECCCEEEEECCHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCCCCHHH
ITLYFMDLDKFKPINDEYGHEFGDQLLLLTSKRLQSCFRKNDFIARLGGDEFTAIIVHKP
EEEEEEEHHHCCCCCCHHCHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECC
LDHIAEALTLRIEQEFEQPFVINGQTIHCTISVGIANYPRNAKNAEDLLKWADKAMYDNK
HHHHHHHHHHHHHHHCCCCEEECCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCH
RKKYKTLKQTS
HHHHHHHHCCC
>Mature Secondary Structure 
SLLKKTREQDYSILVTTQDQQRKRHLLNVISIELLILGLLLIITNICLLRAWLIISMLI
CHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGMSILLGNLILIKKNFNLTLSGHILNILVLSIIIGGNLIVGKTTMSYLGWFYVSPIVAF
HHHHHHHCCEEEEEECCCEEEHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHH
ATLGLTGLVVYGLLAIGAMFLFVFEFYIPIYSISQEYVFFLDNTNHLFIFALIFTVLYHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LVQNLQYELLLKEQNYLLIADKEKFHYLSHHDSLTNLPNRSYFHAHLQTLLENTDTTKEA
HHHCCCEEEEEECCCEEEEECCHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCCCCHHH
ITLYFMDLDKFKPINDEYGHEFGDQLLLLTSKRLQSCFRKNDFIARLGGDEFTAIIVHKP
EEEEEEEHHHCCCCCCHHCHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECC
LDHIAEALTLRIEQEFEQPFVINGQTIHCTISVGIANYPRNAKNAEDLLKWADKAMYDNK
HHHHHHHHHHHHHHHCCCCEEECCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCH
RKKYKTLKQTS
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]