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The map label for this gene is dnaJ [H]

Identifier: 54295398

GI number: 54295398

Start: 2824980

End: 2825720

Strand: Direct

Name: dnaJ [H]

Synonym: lpl2484

Alternate gene names: 54295398

Gene position: 2824980-2825720 (Clockwise)

Preceding gene: 54295397

Following gene: 54295399

Centisome position: 84.44

GC content: 34.82

Gene sequence:

>741_bases
ATGGCCACTGAAAATGCAAATGCAGCAATTGCATTTATGAATTCTTATGAAAACATGTCATTATTTTCTGTCAAGCAAGT
CACAGACTTGCTTTTAAATCATAGAGCACATCTAAAGCTACAAAACGTACCTCCATTTACCCCTCATAATCCTCAACTTA
TTGCTTTAGATAATCCTATGCTTATTAACGCGTTAAAAAACGATCCTGGCATAGCTATCCAATTTATAAATTCGAGATTG
ATAAATTTATTTACACCTTTGACTGCTGCAAAAATTATGCTTGCACATAAAGATAATGATCGTTTCTATCATCAAACGCG
GCCACGCCATGCTTCACTTTTTACTTCTGAAAACCTGAATGATCCCAGGATTAAAGAAATTTATGATCAATATTTTCATA
ATCGAAATCAGAGAAAAAATCGATTTTTTGCACAACAACCCCAAGTTAACGAGGCTGAGGAGTATTTCAGATTTGCGAAT
AGAGATGAAATAAAATTTAATCCCTATAAAGTATTAGGCGTTAACGAAGATGCAAGCTTGGAGGAGATAAAAAAAGCCTA
TAAAAAGTTAGCAATGGCTTGGCATCCTGATAGAGTACAAGCAGGTGAAAATATAGAAGCACGAACGGAACGTTTTAAGA
AACTTGGGGTAGCCTATAATATTTTAATTGATCCTGCCAAACGACAAGAATATGACAATAGACCTCAAAACAGATTCGGA
AGGCATAATCCCATGCAATAA

Upstream 100 bases:

>100_bases
GCAACTATTAATCAAAGCCACTGATCCAGTTAACGCAAGAGCTTACAAAAAATATTTTATTAAACATCCTGCTCATATTT
AGTTATTATTTAATTTCTTA

Downstream 100 bases:

>100_bases
GTGCTTTGTTATTGGGTTAGCAATGGCAACTGTCTTGAATTTTATTCAAGACAGTTGCCGCGCGTGCTGCATATACTAGC
ACACCTGGCAGATTTTTGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MATENANAAIAFMNSYENMSLFSVKQVTDLLLNHRAHLKLQNVPPFTPHNPQLIALDNPMLINALKNDPGIAIQFINSRL
INLFTPLTAAKIMLAHKDNDRFYHQTRPRHASLFTSENLNDPRIKEIYDQYFHNRNQRKNRFFAQQPQVNEAEEYFRFAN
RDEIKFNPYKVLGVNEDASLEEIKKAYKKLAMAWHPDRVQAGENIEARTERFKKLGVAYNILIDPAKRQEYDNRPQNRFG
RHNPMQ

Sequences:

>Translated_246_residues
MATENANAAIAFMNSYENMSLFSVKQVTDLLLNHRAHLKLQNVPPFTPHNPQLIALDNPMLINALKNDPGIAIQFINSRL
INLFTPLTAAKIMLAHKDNDRFYHQTRPRHASLFTSENLNDPRIKEIYDQYFHNRNQRKNRFFAQQPQVNEAEEYFRFAN
RDEIKFNPYKVLGVNEDASLEEIKKAYKKLAMAWHPDRVQAGENIEARTERFKKLGVAYNILIDPAKRQEYDNRPQNRFG
RHNPMQ
>Mature_245_residues
ATENANAAIAFMNSYENMSLFSVKQVTDLLLNHRAHLKLQNVPPFTPHNPQLIALDNPMLINALKNDPGIAIQFINSRLI
NLFTPLTAAKIMLAHKDNDRFYHQTRPRHASLFTSENLNDPRIKEIYDQYFHNRNQRKNRFFAQQPQVNEAEEYFRFANR
DEIKFNPYKVLGVNEDASLEEIKKAYKKLAMAWHPDRVQAGENIEARTERFKKLGVAYNILIDPAKRQEYDNRPQNRFGR
HNPMQ

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI72534740, Length=66, Percent_Identity=50, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI68077166, Length=65, Percent_Identity=50.7692307692308, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI68077168, Length=65, Percent_Identity=50.7692307692308, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786197, Length=64, Percent_Identity=48.4375, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532476, Length=76, Percent_Identity=46.0526315789474, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323119, Length=64, Percent_Identity=46.875, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 28821; Mature: 28690

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATENANAAIAFMNSYENMSLFSVKQVTDLLLNHRAHLKLQNVPPFTPHNPQLIALDNPM
CCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCEEEEECCCE
LINALKNDPGIAIQFINSRLINLFTPLTAAKIMLAHKDNDRFYHQTRPRHASLFTSENLN
EEEEECCCCCEEEEEHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCCCHHEEEECCCCC
DPRIKEIYDQYFHNRNQRKNRFFAQQPQVNEAEEYFRFANRDEIKFNPYKVLGVNEDASL
CCHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCEEECCEEEEECCCCCCH
EEIKKAYKKLAMAWHPDRVQAGENIEARTERFKKLGVAYNILIDPAKRQEYDNRPQNRFG
HHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHCCCCHHHCC
RHNPMQ
CCCCCC
>Mature Secondary Structure 
ATENANAAIAFMNSYENMSLFSVKQVTDLLLNHRAHLKLQNVPPFTPHNPQLIALDNPM
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCEEEEECCCE
LINALKNDPGIAIQFINSRLINLFTPLTAAKIMLAHKDNDRFYHQTRPRHASLFTSENLN
EEEEECCCCCEEEEEHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCCCHHEEEECCCCC
DPRIKEIYDQYFHNRNQRKNRFFAQQPQVNEAEEYFRFANRDEIKFNPYKVLGVNEDASL
CCHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCEEECCEEEEECCCCCCH
EEIKKAYKKLAMAWHPDRVQAGENIEARTERFKKLGVAYNILIDPAKRQEYDNRPQNRFG
HHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHCCCCHHHCC
RHNPMQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA