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The map label for this gene is uhpC [H]

Identifier: 54295389

GI number: 54295389

Start: 2814594

End: 2815961

Strand: Direct

Name: uhpC [H]

Synonym: lpl2474

Alternate gene names: 54295389

Gene position: 2814594-2815961 (Clockwise)

Preceding gene: 54295387

Following gene: 54295390

Centisome position: 84.13

GC content: 39.77

Gene sequence:

>1368_bases
ATGGCATTATTGAGTTTTCTAAAACCTGCTCCATATCTTGATGAAATTCAGGATAAGAACATTGTTAAACGGCAATATCG
TTATTGGCGTATTCGCACCTTTTATGCAATGTATATAGGGTATGCGTTGTTTTATTTTACGCGAAAGAGCTTTACCTTCG
TGATGCCTGCGTTACAAAGCACCTTGGGGATGACTAAAACTGAACTGGGAATGATCGCCAGCATTTTGAGTTTAAGTTAT
GGTATCAGCAAATTTTTGAGTGGAATTCTTGGTGATAAATCTAATCCTCGTTATTTAATGGCAATCGGGCTGATTTTGAC
AGGTGTTTTTAATATTTTGTTTGGATTGTCTTCTACCTGGTGGTTATTCGCTATTTTTTGGGGATTGAATGGTTGGTTTC
AAGGGTGGGGCTGGCCAGGATGTACTAAATTATTAACACATTGGTATTCCCAATCCGAACGTGGCCGTTGGTGGAGTCTT
TGGAATACATCACACAACGTTGGTGGTGCATTAATTCCTTTGATTGTTGCTGTGTGCGCGCAATACTTCGGTTGGCGTTC
AGCCATGTTTGTGCCTGGGATCATTTGCATTTTAGGAGGTATTTTTTTAATCAATCGTTTAAGAGATACCCCACAATCAC
TTGGTTTACCCGCGATAGAGCAATATCATGAAGACTGTTCTGGTTCCGCAAATCACCACCAGGAGAAAACAGAACTCTCA
GTCAAAGAAATTCTTTGGAATTATGTGTTGTGCAACCAATATATTTGGATATTGTCGATTTCTTATTTGTTTATTTACAT
TGTCCGAACGGCCATTAATGATTGGAGCATGTTGTATTTAACGGAAGTGAAAGAGTATTCCTTAATCACTGCAGGCAGTT
GTGTCATATGGTTTGAAGTTGGTGGCTTTTTTGGAAATCTGGTTGCCGGCTGGTCTTCTGACAAAATATTTCAAGGCAAA
CGCAATCCAATCAACGTTCTTTTTACTGCAGGCGTATTTGCCACTTTATTGCTGTTTACGTTAACCAGGGCATATACACC
GTTCCTCGATGCCTTGTTTCTTTTTTTCTTTGGTTTTTTTATCTTTGGACCACAAATGATGATTGGTATGGCCTGTGCGG
AATTAGCACATAAGAAAGCAGCGGCGACTGCAACTGGCTTTGCCGGATTTTTTGCTTATTGTTTAGGTGCTGTTCTGGCC
GGCGCTCCTTTGGGCGCAATTATCAAAAATTACGGCTGGGATAATTTCTTCATCACATTATTTATTTGCTGCTTGATTCC
ATTATTTTTGATGCTGCCGCTCTGGCATGTGAAAGTCAATCCAAAATATCGTCAATCAGAATTTTCAGGCAAATCAGAAT
TTGCTTAG

Upstream 100 bases:

>100_bases
ATCATCAATAGGTATGATCCTGTTAAATTTTCACTAGAAAGATTTGACATACTTTGCGAGTTACATTCTAATCATGTTTT
TTTCATGATCATGGACAATC

Downstream 100 bases:

>100_bases
TGATTAGCTTCCCTGGGTGATCCAGAAAAAGTAGGTCGGACCTGCCTGGGTCCGACCTACTCTTGCTACCTCCACATGAA
AGCCCCTGGGGTATAGAGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MALLSFLKPAPYLDEIQDKNIVKRQYRYWRIRTFYAMYIGYALFYFTRKSFTFVMPALQSTLGMTKTELGMIASILSLSY
GISKFLSGILGDKSNPRYLMAIGLILTGVFNILFGLSSTWWLFAIFWGLNGWFQGWGWPGCTKLLTHWYSQSERGRWWSL
WNTSHNVGGALIPLIVAVCAQYFGWRSAMFVPGIICILGGIFLINRLRDTPQSLGLPAIEQYHEDCSGSANHHQEKTELS
VKEILWNYVLCNQYIWILSISYLFIYIVRTAINDWSMLYLTEVKEYSLITAGSCVIWFEVGGFFGNLVAGWSSDKIFQGK
RNPINVLFTAGVFATLLLFTLTRAYTPFLDALFLFFFGFFIFGPQMMIGMACAELAHKKAAATATGFAGFFAYCLGAVLA
GAPLGAIIKNYGWDNFFITLFICCLIPLFLMLPLWHVKVNPKYRQSEFSGKSEFA

Sequences:

>Translated_455_residues
MALLSFLKPAPYLDEIQDKNIVKRQYRYWRIRTFYAMYIGYALFYFTRKSFTFVMPALQSTLGMTKTELGMIASILSLSY
GISKFLSGILGDKSNPRYLMAIGLILTGVFNILFGLSSTWWLFAIFWGLNGWFQGWGWPGCTKLLTHWYSQSERGRWWSL
WNTSHNVGGALIPLIVAVCAQYFGWRSAMFVPGIICILGGIFLINRLRDTPQSLGLPAIEQYHEDCSGSANHHQEKTELS
VKEILWNYVLCNQYIWILSISYLFIYIVRTAINDWSMLYLTEVKEYSLITAGSCVIWFEVGGFFGNLVAGWSSDKIFQGK
RNPINVLFTAGVFATLLLFTLTRAYTPFLDALFLFFFGFFIFGPQMMIGMACAELAHKKAAATATGFAGFFAYCLGAVLA
GAPLGAIIKNYGWDNFFITLFICCLIPLFLMLPLWHVKVNPKYRQSEFSGKSEFA
>Mature_454_residues
ALLSFLKPAPYLDEIQDKNIVKRQYRYWRIRTFYAMYIGYALFYFTRKSFTFVMPALQSTLGMTKTELGMIASILSLSYG
ISKFLSGILGDKSNPRYLMAIGLILTGVFNILFGLSSTWWLFAIFWGLNGWFQGWGWPGCTKLLTHWYSQSERGRWWSLW
NTSHNVGGALIPLIVAVCAQYFGWRSAMFVPGIICILGGIFLINRLRDTPQSLGLPAIEQYHEDCSGSANHHQEKTELSV
KEILWNYVLCNQYIWILSISYLFIYIVRTAINDWSMLYLTEVKEYSLITAGSCVIWFEVGGFFGNLVAGWSSDKIFQGKR
NPINVLFTAGVFATLLLFTLTRAYTPFLDALFLFFFGFFIFGPQMMIGMACAELAHKKAAATATGFAGFFAYCLGAVLAG
APLGAIIKNYGWDNFFITLFICCLIPLFLMLPLWHVKVNPKYRQSEFSGKSEFA

Specific function: Transport protein for sugar phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=414, Percent_Identity=33.8164251207729, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI4503847, Length=414, Percent_Identity=33.8164251207729, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI256219483, Length=414, Percent_Identity=33.8164251207729, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI256219543, Length=436, Percent_Identity=31.651376146789, Blast_Score=229, Evalue=5e-60,
Organism=Homo sapiens, GI256219564, Length=340, Percent_Identity=31.4705882352941, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI46361976, Length=441, Percent_Identity=24.7165532879819, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI38093649, Length=423, Percent_Identity=27.6595744680851, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI223717983, Length=424, Percent_Identity=27.5943396226415, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI14150047, Length=326, Percent_Identity=24.5398773006135, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI49619231, Length=417, Percent_Identity=24.4604316546763, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87082310, Length=436, Percent_Identity=48.8532110091743, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1788573, Length=451, Percent_Identity=37.6940133037694, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI2367259, Length=434, Percent_Identity=30.184331797235, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI2367379, Length=430, Percent_Identity=24.8837209302326, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17561094, Length=412, Percent_Identity=25.4854368932039, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17542316, Length=462, Percent_Identity=24.6753246753247, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI133901856, Length=465, Percent_Identity=23.6559139784946, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI133901854, Length=467, Percent_Identity=23.982869379015, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI133930953, Length=461, Percent_Identity=23.644251626898, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17564202, Length=424, Percent_Identity=22.6415094339623, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17564204, Length=323, Percent_Identity=24.1486068111455, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17539138, Length=322, Percent_Identity=24.223602484472, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24656866, Length=480, Percent_Identity=24.7916666666667, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI45550478, Length=480, Percent_Identity=24.7916666666667, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24656861, Length=480, Percent_Identity=24.7916666666667, Blast_Score=119, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51709; Mature: 51578

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLSFLKPAPYLDEIQDKNIVKRQYRYWRIRTFYAMYIGYALFYFTRKSFTFVMPALQS
CCHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGMTKTELGMIASILSLSYGISKFLSGILGDKSNPRYLMAIGLILTGVFNILFGLSSTW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
WLFAIFWGLNGWFQGWGWPGCTKLLTHWYSQSERGRWWSLWNTSHNVGGALIPLIVAVCA
HHHHHHHHCCHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHH
QYFGWRSAMFVPGIICILGGIFLINRLRDTPQSLGLPAIEQYHEDCSGSANHHQEKTELS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCCCCHHHHHHH
VKEILWNYVLCNQYIWILSISYLFIYIVRTAINDWSMLYLTEVKEYSLITAGSCVIWFEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHCEEECCCEEEEEEH
GGFFGNLVAGWSSDKIFQGKRNPINVLFTAGVFATLLLFTLTRAYTPFLDALFLFFFGFF
HHHHHHHHHCCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFGPQMMIGMACAELAHKKAAATATGFAGFFAYCLGAVLAGAPLGAIIKNYGWDNFFITL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
FICCLIPLFLMLPLWHVKVNPKYRQSEFSGKSEFA
HHHHHHHHHHHHHHHHEECCCCHHHHHCCCCCCCC
>Mature Secondary Structure 
ALLSFLKPAPYLDEIQDKNIVKRQYRYWRIRTFYAMYIGYALFYFTRKSFTFVMPALQS
CHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGMTKTELGMIASILSLSYGISKFLSGILGDKSNPRYLMAIGLILTGVFNILFGLSSTW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
WLFAIFWGLNGWFQGWGWPGCTKLLTHWYSQSERGRWWSLWNTSHNVGGALIPLIVAVCA
HHHHHHHHCCHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHH
QYFGWRSAMFVPGIICILGGIFLINRLRDTPQSLGLPAIEQYHEDCSGSANHHQEKTELS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCCCCHHHHHHH
VKEILWNYVLCNQYIWILSISYLFIYIVRTAINDWSMLYLTEVKEYSLITAGSCVIWFEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHCEEECCCEEEEEEH
GGFFGNLVAGWSSDKIFQGKRNPINVLFTAGVFATLLLFTLTRAYTPFLDALFLFFFGFF
HHHHHHHHHCCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFGPQMMIGMACAELAHKKAAATATGFAGFFAYCLGAVLAGAPLGAIIKNYGWDNFFITL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
FICCLIPLFLMLPLWHVKVNPKYRQSEFSGKSEFA
HHHHHHHHHHHHHHHHEECCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]