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The map label for this gene is mltA [C]

Identifier: 54295381

GI number: 54295381

Start: 2806569

End: 2807942

Strand: Direct

Name: mltA [C]

Synonym: lpl2466

Alternate gene names: 54295381

Gene position: 2806569-2807942 (Clockwise)

Preceding gene: 54295373

Following gene: 54295382

Centisome position: 83.89

GC content: 43.16

Gene sequence:

>1374_bases
ATGTTTCAATCCATTCTAATAATTGCACTAATGACTTTTAGCTTCATCACTCAAGCAGCCCTCCCTGCTGATCCAATCCA
GCGCTGCCTGGATATTAGAAGGCTCGTGGATATCACCTCAAGACAGAAAATGGCAGCCAAAGAACCCGGGGTGTTACGTT
TTAAATTTCATAAAATTTCAGCATCAGAACTCCCGTTAGATAACCCTGTGGGTAATATGGATGAAGTTATCCAGGCATTA
AATAATCAGATTGAAAACTGCAATAATAGCTATGGTGAATTCCAGACAGTAACAATCGCTGGCCATCAATTCAAACGCCA
GGAATGGTGCTTAAATACCAACAAAAAAATGCTGACTCTGGCAAAAGCCGCCCATGGTGATTTTAAAAAATTTTTATCGA
GCATCAAAACCGAGTTTGACTGGTATAAAAGCGATGGCTGGCCGGAAAACCACGCAGGATTTAAAAAAGGTGAGTTTCAA
TTTACTGCCTATTACGCTCCAGCCGCTGTTGAGGCCCGCTCTGAGCGTGGTGGAGCATTTCTGTATCCTCTCTATAGCAA
CCCCGGGGTTGTTAGCGTTGCGTTGGAAAGTAAAAAATATAATTTGAAAACTCCTCTTTGCGGGGTGGATCCGCTTAGCA
AAGTGATGCGTGGATTTTGTCTGAAAAATGCCGATGGGACCTACTCTGTAGCACCAGATCGAGAGGAAATTGAGCATGGG
GCTTTAAATCCAAAATATATAATTGGCTATCTTAAAGACCCAAATGACTCTGCTTTTTTAATGCTACAAGGCTCTGGTTC
ATTACTCCTTGATGGCAAATTGTTTCACATCAATTACGACGGTGCCAACGGCAGGCCACGCACGATGCTTGGTCGCATAG
TCCAATGCGCTCAAGATCCAACCTGTGGTGGCAATCTTGACACAATGGAACGTTGCGCTAAAGATCCGAAATGCCATGAT
GAAGCCAAGTTACGCTGCAACGTATCTAAAAAAATCAGGCAAAGCGCTGCATCAGAAAAGCTCATTCGGCAATATCTGAA
CAATCTTACCCCTGATAAAGCAGACAATTTACGGAATCGAGATCAAAGCTATGTATTTTTTGCCAAAGAAGATGGTGGCC
CTTATGGTTCAGAAAATATTTCTCTAACCCCCCATGTGTCATGTGCAACCGATCACAGGGTTATTCCTGTTGGAATGAAC
TTTATCTATCATTGCAAAAAAGCTACGTCATGGTGTGTGGCTCAGGATGCAGGCGGCGCCATTATAGGGGCTCATGTTGA
CGTCTATAAAGGTGAGGGAAATCAAGCAGGTGTGGAAGCAAATCAGTTAAATCATACTGGAACGTTATTTGTGGCACTAC
CTAAACGGAAATAG

Upstream 100 bases:

>100_bases
ATCTCTTTGATGAGTTGGCCAATAGCCTATATAATTCATGTTACTAATTGAAATCAATGGACGGGCAATGCCTCAACCAT
AGCTAAGCTAAAGGATACCA

Downstream 100 bases:

>100_bases
AAAGAAGGCAACCAATACTTATTTCGAGTAATTACTTTTATTGGCTATGGCCATTTAGGGTGCTGCTAATCTACAACTGA
ATAAATAAGAATGGTTTTTG

Product: hypothetical protein

Products: Muramic Acid Residue [C]

Alternate protein names: MltA Domain-Containing Protein; MltA Domain Protein; Membrane-Bound Lytic Murein Transglycosylase; Transglycosylase; MltA Family Protein; Peptidoglycan N-Acetylmuramoylhydrolase

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MFQSILIIALMTFSFITQAALPADPIQRCLDIRRLVDITSRQKMAAKEPGVLRFKFHKISASELPLDNPVGNMDEVIQAL
NNQIENCNNSYGEFQTVTIAGHQFKRQEWCLNTNKKMLTLAKAAHGDFKKFLSSIKTEFDWYKSDGWPENHAGFKKGEFQ
FTAYYAPAAVEARSERGGAFLYPLYSNPGVVSVALESKKYNLKTPLCGVDPLSKVMRGFCLKNADGTYSVAPDREEIEHG
ALNPKYIIGYLKDPNDSAFLMLQGSGSLLLDGKLFHINYDGANGRPRTMLGRIVQCAQDPTCGGNLDTMERCAKDPKCHD
EAKLRCNVSKKIRQSAASEKLIRQYLNNLTPDKADNLRNRDQSYVFFAKEDGGPYGSENISLTPHVSCATDHRVIPVGMN
FIYHCKKATSWCVAQDAGGAIIGAHVDVYKGEGNQAGVEANQLNHTGTLFVALPKRK

Sequences:

>Translated_457_residues
MFQSILIIALMTFSFITQAALPADPIQRCLDIRRLVDITSRQKMAAKEPGVLRFKFHKISASELPLDNPVGNMDEVIQAL
NNQIENCNNSYGEFQTVTIAGHQFKRQEWCLNTNKKMLTLAKAAHGDFKKFLSSIKTEFDWYKSDGWPENHAGFKKGEFQ
FTAYYAPAAVEARSERGGAFLYPLYSNPGVVSVALESKKYNLKTPLCGVDPLSKVMRGFCLKNADGTYSVAPDREEIEHG
ALNPKYIIGYLKDPNDSAFLMLQGSGSLLLDGKLFHINYDGANGRPRTMLGRIVQCAQDPTCGGNLDTMERCAKDPKCHD
EAKLRCNVSKKIRQSAASEKLIRQYLNNLTPDKADNLRNRDQSYVFFAKEDGGPYGSENISLTPHVSCATDHRVIPVGMN
FIYHCKKATSWCVAQDAGGAIIGAHVDVYKGEGNQAGVEANQLNHTGTLFVALPKRK
>Mature_457_residues
MFQSILIIALMTFSFITQAALPADPIQRCLDIRRLVDITSRQKMAAKEPGVLRFKFHKISASELPLDNPVGNMDEVIQAL
NNQIENCNNSYGEFQTVTIAGHQFKRQEWCLNTNKKMLTLAKAAHGDFKKFLSSIKTEFDWYKSDGWPENHAGFKKGEFQ
FTAYYAPAAVEARSERGGAFLYPLYSNPGVVSVALESKKYNLKTPLCGVDPLSKVMRGFCLKNADGTYSVAPDREEIEHG
ALNPKYIIGYLKDPNDSAFLMLQGSGSLLLDGKLFHINYDGANGRPRTMLGRIVQCAQDPTCGGNLDTMERCAKDPKCHD
EAKLRCNVSKKIRQSAASEKLIRQYLNNLTPDKADNLRNRDQSYVFFAKEDGGPYGSENISLTPHVSCATDHRVIPVGMN
FIYHCKKATSWCVAQDAGGAIIGAHVDVYKGEGNQAGVEANQLNHTGTLFVALPKRK

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. Optimal Activity Is Between pH 4.0 And 4.5; Loses Its Activity Rapidly At Temperatures Above 30 Degrees Celsius. Degrades Murein Glycan Stra

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 50734; Mature: 50734

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQSILIIALMTFSFITQAALPADPIQRCLDIRRLVDITSRQKMAAKEPGVLRFKFHKIS
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
ASELPLDNPVGNMDEVIQALNNQIENCNNSYGEFQTVTIAGHQFKRQEWCLNTNKKMLTL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHCCCCCCEEEE
AKAAHGDFKKFLSSIKTEFDWYKSDGWPENHAGFKKGEFQFTAYYAPAAVEARSERGGAF
HHHHCHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCEEEEEEECCHHHEHHCCCCCEE
LYPLYSNPGVVSVALESKKYNLKTPLCGVDPLSKVMRGFCLKNADGTYSVAPDREEIEHG
EEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHEECCCCCCEEECCCHHHHHHC
ALNPKYIIGYLKDPNDSAFLMLQGSGSLLLDGKLFHINYDGANGRPRTMLGRIVQCAQDP
CCCCEEEEEEEECCCCCEEEEEECCCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHCCC
TCGGNLDTMERCAKDPKCHDEAKLRCNVSKKIRQSAASEKLIRQYLNNLTPDKADNLRNR
CCCCCHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
DQSYVFFAKEDGGPYGSENISLTPHVSCATDHRVIPVGMNFIYHCKKATSWCVAQDAGGA
CCCEEEEEECCCCCCCCCCEEECCCEEECCCCEEEEECCCHHHHHHCCCCEEEEECCCCE
IIGAHVDVYKGEGNQAGVEANQLNHTGTLFVALPKRK
EEEEEEEEEECCCCCCCCCHHCCCCCEEEEEEECCCC
>Mature Secondary Structure
MFQSILIIALMTFSFITQAALPADPIQRCLDIRRLVDITSRQKMAAKEPGVLRFKFHKIS
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
ASELPLDNPVGNMDEVIQALNNQIENCNNSYGEFQTVTIAGHQFKRQEWCLNTNKKMLTL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHCCCCCCEEEE
AKAAHGDFKKFLSSIKTEFDWYKSDGWPENHAGFKKGEFQFTAYYAPAAVEARSERGGAF
HHHHCHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCEEEEEEECCHHHEHHCCCCCEE
LYPLYSNPGVVSVALESKKYNLKTPLCGVDPLSKVMRGFCLKNADGTYSVAPDREEIEHG
EEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHEECCCCCCEEECCCHHHHHHC
ALNPKYIIGYLKDPNDSAFLMLQGSGSLLLDGKLFHINYDGANGRPRTMLGRIVQCAQDP
CCCCEEEEEEEECCCCCEEEEEECCCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHCCC
TCGGNLDTMERCAKDPKCHDEAKLRCNVSKKIRQSAASEKLIRQYLNNLTPDKADNLRNR
CCCCCHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
DQSYVFFAKEDGGPYGSENISLTPHVSCATDHRVIPVGMNFIYHCKKATSWCVAQDAGGA
CCCEEEEEECCCCCCCCCCEEECCCEEECCCCEEEEECCCHHHHHHCCCCEEEEECCCCE
IIGAHVDVYKGEGNQAGVEANQLNHTGTLFVALPKRK
EEEEEEEEEECCCCCCCCCHHCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA