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The map label for this gene is aspB [H]

Identifier: 54295369

GI number: 54295369

Start: 2796026

End: 2797192

Strand: Direct

Name: aspB [H]

Synonym: lpl2454

Alternate gene names: 54295369

Gene position: 2796026-2797192 (Clockwise)

Preceding gene: 54295368

Following gene: 54295370

Centisome position: 83.57

GC content: 43.87

Gene sequence:

>1167_bases
ATGAACCAATGTGAAAAAAAGAACTTGCCCAAAGATTCCGCAACAGTTGCCATCAATTCTCTGGCTCAACAAAAAATTAA
CGCAGGAATCAAAATTCATAATCTCAGTGCTGGAGAACCCAAATTACCCCCCCATCCCTCCATAATAAATGCCGTCACAC
AAGCTATGGAACAAGGACACACCCTTTATCCTCCAATAATGGGAATTCCTGAATTACGTCATCTGGGCTGTGAATGGATG
CATCGATCCTATGATTGCTCATTCCAAAATGAGCAATGCCTGGTTGTGAATGGTGGAAAACTTGGCATTTATTTACTCAT
GCAATTATTACTGCAGCCTAACGACGAAGTCATTATTCCTTCTCCCTACTGGGTTTCCTATCCAGCCATGGTTAGCCTGT
TTGGCGGCACCCCCGTGCCAGTTGAAACGACAGAAGCCGAAGAATGGAAACTAACGCCACAGGCACTGCAAAAAGCGTGT
ACCACAAAAAGTAAAATACTCATTCTGAATAATGCCACCAATCCCACCGGAGCTCTGTATACCCAGTCCGAGCTGATTCA
CTTATTGCAAACTGCCAAGAAGCATAATCTTTTAGTGATCTCTGATGAAGTTTACAGCGAACTAACCTATGATGGGCATC
ATTACGTATCCTGTGGTTCTTTACCCCAGTTTCGGGAGAGTGTCATCATCATTCAAAGCTGTTCAAAAAACTTTTCCATG
ACCGGGTGGCGAGTGGGTTTTATTTTTGCCCCGGAAGTATTCATCAAACCTTTAAGCGCCCTGGTCAGTCAAAGCACCAG
TGGAGTAACCACCCTTAGCCAATGGGCCGCTGTGGCTGCGCTGCAAGAAGTAAATCAAGTCAATATCTGGGTTCAGCAAA
ACATGGAAAAAAGAAGAAATTGCCTCCTCCGCACCTTGCATGACTATCTGGGATTGACCATAACACCTCCAATTTCCTCA
CTTTATGTTTTTCTTTCCCTAAAGGATATTGGCTGCAAAAATCAAAATTCCGAGGAGTTTTGTAAACAAGTATTGGATAA
GGCAAATGTTGCGATGGTACCGGGAATCGCCTTTGGTAAAGAGGGTTACGTCCGCTTGTCTTTTGGAGGCAATGAAGACG
ATTTAAAATCAGGTATTTATGCTCTGGCGCAATGGCTGCATCGCTAA

Upstream 100 bases:

>100_bases
AATATTATGACTATTTATCCAGGCAATATCACTTGCAGCAGGATTTCGTGAATCAATTATTCAAGATAATTATCTCAAAC
TCAAAAAAGGTCCAAAAATA

Downstream 100 bases:

>100_bases
TTCAAGTAATTCATTACTTTGCAAGAAGCATGACCAGACCTCTTACATAACTAGTCTCTTTTATTTTAAACGTTTCTGTG
GTGCCTCATTTAACGACTCT

Product: hypothetical protein

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNQCEKKNLPKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGHTLYPPIMGIPELRHLGCEWM
HRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIPSPYWVSYPAMVSLFGGTPVPVETTEAEEWKLTPQALQKAC
TTKSKILILNNATNPTGALYTQSELIHLLQTAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRESVIIIQSCSKNFSM
TGWRVGFIFAPEVFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRNCLLRTLHDYLGLTITPPISS
LYVFLSLKDIGCKNQNSEEFCKQVLDKANVAMVPGIAFGKEGYVRLSFGGNEDDLKSGIYALAQWLHR

Sequences:

>Translated_388_residues
MNQCEKKNLPKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGHTLYPPIMGIPELRHLGCEWM
HRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIPSPYWVSYPAMVSLFGGTPVPVETTEAEEWKLTPQALQKAC
TTKSKILILNNATNPTGALYTQSELIHLLQTAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRESVIIIQSCSKNFSM
TGWRVGFIFAPEVFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRNCLLRTLHDYLGLTITPPISS
LYVFLSLKDIGCKNQNSEEFCKQVLDKANVAMVPGIAFGKEGYVRLSFGGNEDDLKSGIYALAQWLHR
>Mature_388_residues
MNQCEKKNLPKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGHTLYPPIMGIPELRHLGCEWM
HRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIPSPYWVSYPAMVSLFGGTPVPVETTEAEEWKLTPQALQKAC
TTKSKILILNNATNPTGALYTQSELIHLLQTAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRESVIIIQSCSKNFSM
TGWRVGFIFAPEVFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRNCLLRTLHDYLGLTITPPISS
LYVFLSLKDIGCKNQNSEEFCKQVLDKANVAMVPGIAFGKEGYVRLSFGGNEDDLKSGIYALAQWLHR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=403, Percent_Identity=28.287841191067, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI169881279, Length=403, Percent_Identity=28.287841191067, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=29.042904290429, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI56713254, Length=395, Percent_Identity=26.5822784810127, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI56713256, Length=394, Percent_Identity=26.1421319796954, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4507369, Length=379, Percent_Identity=20.5804749340369, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI149944424, Length=361, Percent_Identity=25.4847645429363, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI187936925, Length=324, Percent_Identity=25.3086419753086, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI14211921, Length=324, Percent_Identity=25.3086419753086, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1788722, Length=375, Percent_Identity=28.2666666666667, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786816, Length=390, Percent_Identity=24.8717948717949, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788627, Length=280, Percent_Identity=27.1428571428571, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=197, Percent_Identity=35.0253807106599, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=197, Percent_Identity=35.0253807106599, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=22.3118279569892, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=199, Percent_Identity=29.1457286432161, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71981209, Length=339, Percent_Identity=22.4188790560472, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=288, Percent_Identity=28.4722222222222, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6320317, Length=343, Percent_Identity=22.4489795918367, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573069, Length=322, Percent_Identity=24.8447204968944, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646114, Length=322, Percent_Identity=24.8447204968944, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28573067, Length=322, Percent_Identity=24.8447204968944, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28573065, Length=322, Percent_Identity=24.8447204968944, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI18859735, Length=351, Percent_Identity=21.0826210826211, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43102; Mature: 43102

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQCEKKNLPKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGH
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
TLYPPIMGIPELRHLGCEWMHRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIP
EECCCCCCCHHHHHHCHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEC
SPYWVSYPAMVSLFGGTPVPVETTEAEEWKLTPQALQKACTTKSKILILNNATNPTGALY
CCCCCCCHHHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHCCCCEEEEEECCCCCCCCEE
TQSELIHLLQTAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRESVIIIQSCSKNFSM
EHHHHHHHHHHHHHCCEEEEEHHHHHHHCCCCCEEEEECCCHHHHHHEEEEEECCCCCCC
TGWRVGFIFAPEVFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRN
CCEEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHH
CLLRTLHDYLGLTITPPISSLYVFLSLKDIGCKNQNSEEFCKQVLDKANVAMVPGIAFGK
HHHHHHHHHCCEEECCCHHHEEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCEEECC
EGYVRLSFGGNEDDLKSGIYALAQWLHR
CCEEEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQCEKKNLPKDSATVAINSLAQQKINAGIKIHNLSAGEPKLPPHPSIINAVTQAMEQGH
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
TLYPPIMGIPELRHLGCEWMHRSYDCSFQNEQCLVVNGGKLGIYLLMQLLLQPNDEVIIP
EECCCCCCCHHHHHHCHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEC
SPYWVSYPAMVSLFGGTPVPVETTEAEEWKLTPQALQKACTTKSKILILNNATNPTGALY
CCCCCCCHHHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHCCCCEEEEEECCCCCCCCEE
TQSELIHLLQTAKKHNLLVISDEVYSELTYDGHHYVSCGSLPQFRESVIIIQSCSKNFSM
EHHHHHHHHHHHHHCCEEEEEHHHHHHHCCCCCEEEEECCCHHHHHHEEEEEECCCCCCC
TGWRVGFIFAPEVFIKPLSALVSQSTSGVTTLSQWAAVAALQEVNQVNIWVQQNMEKRRN
CCEEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHH
CLLRTLHDYLGLTITPPISSLYVFLSLKDIGCKNQNSEEFCKQVLDKANVAMVPGIAFGK
HHHHHHHHHCCEEECCCHHHEEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCEEECC
EGYVRLSFGGNEDDLKSGIYALAQWLHR
CCEEEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]