| Definition | Legionella pneumophila str. Lens, complete genome. |
|---|---|
| Accession | NC_006369 |
| Length | 3,345,687 |
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The map label for this gene is phbB [H]
Identifier: 54295222
GI number: 54295222
Start: 2625469
End: 2626209
Strand: Direct
Name: phbB [H]
Synonym: lpl2305
Alternate gene names: 54295222
Gene position: 2625469-2626209 (Clockwise)
Preceding gene: 54295221
Following gene: 54295223
Centisome position: 78.47
GC content: 45.21
Gene sequence:
>741_bases ATGGAAAGGAAAATAGCCATTGTAACAGGAGGTACGGGCGGCATTGGGACTGCCATTTGTCGACGATTAGCAGCAGACTA TTCTGTCATTGCCTGTTACTTCAAAAACGGCAATCACGAAGAAGCGATTCAGTGGCAAAGAACACAACAACAAGCCGGGT TTGATATCGATATACTGTATGCTAACATCGCGCAGTTTCATGATTGTGAAAAACTGGTTGCCCTGGTCATGGAACGCTAT GGTCGTATTGACGTTTTGATCAACAATGCCGGTATAACCCAGGACTCCAGTTTAAAAAAGATGTCGCCTGAGCAATGGCA GTCCGTATTGGATGCTAACCTCACCAGTGTGTTTAACATGACACGAAATATATTGCCTGCCATGCTTGAGAAAGGATATG GTCGTATCATCTCCATCTCTTCCATTAATGGGCGTAAGGGTCAGTTTGGGCAATGTAACTACGCAGCAACCAAGGCTGCA TTGTTTGGCTTTACCAAAAGCCTGGCTCTTGAGGTGGCCAACAAAGGCATCACAGTAAATACTATTTCGCCTGGCTATAT TGAAACGCCTATGCTGAGCACAATGCGTGAAGACGTTTTAAATACTATAATTTCAGCAATACCCGTTGGGCGTTTGGGGC TCCCACAAGATGTTGCAGAAGCCGTTGCCTTTTTGGCATCACCTGTATCAGGCTTTATCACAGGAGCCAACCTGGATGTC AATGGTGGTCAATACATGTAA
Upstream 100 bases:
>100_bases GGGATTAACCGGGTTTTTAGTGTTAAAAATGACTTCTCTCAAACGCTAGTTGATAAGGTGTTTTTATAAAGAAAAACCGA TTTAATTAAGGAGAATGCTC
Downstream 100 bases:
>100_bases AAACCAGAGAGGTAAAAATCAGGGAGCAATGATGATTCAAACAGGGATTTGAAAAGTTGCTCCTCTCTTTCAAGGAGGAG AAGTGATGCATCGATTTCAC
Product: hypothetical protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 246; Mature: 246
Protein sequence:
>246_residues MERKIAIVTGGTGGIGTAICRRLAADYSVIACYFKNGNHEEAIQWQRTQQQAGFDIDILYANIAQFHDCEKLVALVMERY GRIDVLINNAGITQDSSLKKMSPEQWQSVLDANLTSVFNMTRNILPAMLEKGYGRIISISSINGRKGQFGQCNYAATKAA LFGFTKSLALEVANKGITVNTISPGYIETPMLSTMREDVLNTIISAIPVGRLGLPQDVAEAVAFLASPVSGFITGANLDV NGGQYM
Sequences:
>Translated_246_residues MERKIAIVTGGTGGIGTAICRRLAADYSVIACYFKNGNHEEAIQWQRTQQQAGFDIDILYANIAQFHDCEKLVALVMERY GRIDVLINNAGITQDSSLKKMSPEQWQSVLDANLTSVFNMTRNILPAMLEKGYGRIISISSINGRKGQFGQCNYAATKAA LFGFTKSLALEVANKGITVNTISPGYIETPMLSTMREDVLNTIISAIPVGRLGLPQDVAEAVAFLASPVSGFITGANLDV NGGQYM >Mature_246_residues MERKIAIVTGGTGGIGTAICRRLAADYSVIACYFKNGNHEEAIQWQRTQQQAGFDIDILYANIAQFHDCEKLVALVMERY GRIDVLINNAGITQDSSLKKMSPEQWQSVLDANLTSVFNMTRNILPAMLEKGYGRIISISSINGRKGQFGQCNYAATKAA LFGFTKSLALEVANKGITVNTISPGYIETPMLSTMREDVLNTIISAIPVGRLGLPQDVAEAVAFLASPVSGFITGANLDV NGGQYM
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=37.5968992248062, Blast_Score=155, Evalue=3e-38, Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=34.4262295081967, Blast_Score=133, Evalue=1e-31, Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=34.0248962655602, Blast_Score=124, Evalue=7e-29, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=31.640625, Blast_Score=115, Evalue=4e-26, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=32.520325203252, Blast_Score=110, Evalue=2e-24, Organism=Homo sapiens, GI59889578, Length=193, Percent_Identity=37.3056994818653, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=30.5220883534137, Blast_Score=108, Evalue=4e-24, Organism=Homo sapiens, GI4758504, Length=257, Percent_Identity=32.295719844358, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI4504505, Length=143, Percent_Identity=38.4615384615385, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=34.2541436464088, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI66933014, Length=169, Percent_Identity=31.9526627218935, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=33.8383838383838, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=27.1317829457364, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI83715985, Length=257, Percent_Identity=29.9610894941634, Blast_Score=88, Evalue=5e-18, Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=27.979274611399, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=28.2157676348548, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=27.5132275132275, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI31542939, Length=203, Percent_Identity=29.5566502463054, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI7705925, Length=168, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI7657478, Length=197, Percent_Identity=29.9492385786802, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI157739938, Length=200, Percent_Identity=24, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI223718074, Length=210, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI40807363, Length=194, Percent_Identity=26.8041237113402, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503301, Length=204, Percent_Identity=27.4509803921569, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI4503817, Length=192, Percent_Identity=23.9583333333333, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI150247226, Length=204, Percent_Identity=28.4313725490196, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI4504503, Length=218, Percent_Identity=27.0642201834862, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI210032110, Length=220, Percent_Identity=22.7272727272727, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI226371731, Length=192, Percent_Identity=27.0833333333333, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI302344755, Length=109, Percent_Identity=32.1100917431193, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=43.6734693877551, Blast_Score=204, Evalue=4e-54, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=34.5238095238095, Blast_Score=135, Evalue=4e-33, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=33.8709677419355, Blast_Score=130, Evalue=8e-32, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=30.8943089430894, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI1790717, Length=184, Percent_Identity=33.695652173913, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=29.8755186721992, Blast_Score=107, Evalue=9e-25, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=32.1138211382114, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=28.2868525896414, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=31.4285714285714, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=29.7959183673469, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=28.1124497991968, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=29.2307692307692, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI1787820, Length=226, Percent_Identity=29.646017699115, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1787526, Length=253, Percent_Identity=28.4584980237154, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1786701, Length=104, Percent_Identity=37.5, Blast_Score=69, Evalue=3e-13, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=41.2955465587045, Blast_Score=174, Evalue=3e-44, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=41.1290322580645, Blast_Score=174, Evalue=4e-44, Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=33.739837398374, Blast_Score=139, Evalue=1e-33, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=35.1778656126482, Blast_Score=131, Evalue=4e-31, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=30.4182509505703, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=30.5343511450382, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=32.3308270676692, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=31.0483870967742, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=32.1285140562249, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=29.1666666666667, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=28.6792452830189, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17568967, Length=185, Percent_Identity=34.0540540540541, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=29.6875, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=29.3436293436293, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17563726, Length=254, Percent_Identity=27.9527559055118, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=28.2442748091603, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=27.4131274131274, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=29.6296296296296, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17538182, Length=232, Percent_Identity=30.1724137931034, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=27.9527559055118, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=28.125, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=28.030303030303, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=30.4511278195489, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=28.4615384615385, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI193204405, Length=256, Percent_Identity=27.734375, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI193203115, Length=249, Percent_Identity=26.5060240963855, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI193203117, Length=249, Percent_Identity=26.5060240963855, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=28.4046692607004, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17561272, Length=167, Percent_Identity=29.940119760479, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=29.2490118577075, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17567345, Length=189, Percent_Identity=28.042328042328, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=26.7175572519084, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=28.2352941176471, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=25.8883248730964, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17558006, Length=220, Percent_Identity=29.0909090909091, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=25.1028806584362, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=156, Percent_Identity=39.1025641025641, Blast_Score=103, Evalue=3e-23, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=29.6, Blast_Score=96, Evalue=4e-21, Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=29.0155440414508, Blast_Score=80, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6322795, Length=273, Percent_Identity=28.9377289377289, Blast_Score=73, Evalue=5e-14, Organism=Saccharomyces cerevisiae, GI6322227, Length=201, Percent_Identity=25.3731343283582, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=38.1147540983607, Blast_Score=161, Evalue=4e-40, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=36.2549800796813, Blast_Score=147, Evalue=6e-36, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=31.496062992126, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=32.5301204819277, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=29.9180327868852, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=30.8943089430894, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI18859837, Length=229, Percent_Identity=31.8777292576419, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI24644337, Length=174, Percent_Identity=36.2068965517241, Blast_Score=92, Evalue=2e-19, Organism=Drosophila melanogaster, GI17737361, Length=240, Percent_Identity=28.3333333333333, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=28.643216080402, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24581726, Length=128, Percent_Identity=33.59375, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24665243, Length=202, Percent_Identity=29.2079207920792, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI221331218, Length=202, Percent_Identity=29.2079207920792, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=30.6878306878307, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=30.6878306878307, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24641232, Length=243, Percent_Identity=25.5144032921811, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI24665247, Length=203, Percent_Identity=29.5566502463054, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI221331216, Length=203, Percent_Identity=29.5566502463054, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=30.1587301587302, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI116007236, Length=237, Percent_Identity=25.7383966244726, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI281364892, Length=172, Percent_Identity=29.0697674418605, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI21355631, Length=206, Percent_Identity=26.2135922330097, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21356301, Length=193, Percent_Identity=29.0155440414508, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24640492, Length=197, Percent_Identity=25.3807106598985, Blast_Score=64, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26650; Mature: 26650
Theoretical pI: Translated: 7.29; Mature: 7.29
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 4.9 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MERKIAIVTGGTGGIGTAICRRLAADYSVIACYFKNGNHEEAIQWQRTQQQAGFDIDILY CCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEHH ANIAQFHDCEKLVALVMERYGRIDVLINNAGITQDSSLKKMSPEQWQSVLDANLTSVFNM HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHH TRNILPAMLEKGYGRIISISSINGRKGQFGQCNYAATKAALFGFTKSLALEVANKGITVN HHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE TISPGYIETPMLSTMREDVLNTIISAIPVGRLGLPQDVAEAVAFLASPVSGFITGANLDV ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHEECCEEEC NGGQYM CCCCCC >Mature Secondary Structure MERKIAIVTGGTGGIGTAICRRLAADYSVIACYFKNGNHEEAIQWQRTQQQAGFDIDILY CCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEHH ANIAQFHDCEKLVALVMERYGRIDVLINNAGITQDSSLKKMSPEQWQSVLDANLTSVFNM HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHH TRNILPAMLEKGYGRIISISSINGRKGQFGQCNYAATKAALFGFTKSLALEVANKGITVN HHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE TISPGYIETPMLSTMREDVLNTIISAIPVGRLGLPQDVAEAVAFLASPVSGFITGANLDV ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHEECCEEEC NGGQYM CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2670935 [H]