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The map label for this gene is hemN [H]

Identifier: 54295196

GI number: 54295196

Start: 2593575

End: 2594702

Strand: Direct

Name: hemN [H]

Synonym: lpl2276

Alternate gene names: 54295196

Gene position: 2593575-2594702 (Clockwise)

Preceding gene: 54295193

Following gene: 54295198

Centisome position: 77.52

GC content: 38.74

Gene sequence:

>1128_bases
ATGCTTCCGTTATCCTTGTACATTCATATTCCCTGGTGCATCAGAAAATGCCCATACTGTGATTTTAACTCACACAAAAG
CCCTGATGTTTTACCCGAACACCAGTATATTCAGGCTTTGATTGAAGACCTTAAAACGGATATTTCCTCATACAATACCC
GTGAAATTAACTCCATTTTTATTGGTGGCGGCACACCCAGTTTATTTTCAGCCGAAGCTTATAACAACTTATTTAATGAA
TTAAAACGCATACTCCCCTTTGCAAAAAATATTGAAATCACAATGGAAGCCAATCCCGGTACTGTAGAACAACATCGATT
TACTGATTATAGACAATCAGGAATCAATCGTCTTTCTTTGGGAATTCAAAGCTTTAATCCCAATCATTTAAAAATTCTTG
GCCGTATTCATGACGAGAAACAAGCCCATTCTGCTATAGATACTGCCCGTAAAGCCGGCTTTGATAATCTCAATCTTGAT
ATCATGCACAGTTTACCTAATCAAAGTATAACGCAGGGATTAGAGGATCTTAAGACCGCATTATCCTATCAACCTGAGCA
TTTATCCTGGTATCAATTAACCATAGAACCGAATACTGTATTTTACAAGCATACTCCTCCCCTGCCTTCTGAAGAAGAAG
ATTACTTGCTGGAGGAGCAAGGATTTGCCCTGTTATATAATTCCGGATATCACCGCTATGAAATTTCTGCCTTTTCCAAA
CCGGAAAAGCAAGCCAGACACAATATCAATTATTGGCTATTCGGTGATTATTTGGGTATAGGCGCTGGTGCCCATGGAAA
AATGACAACCCCAAACGCAATAATAAGAACCCGTAAGCACCGTCAACCCAAAGATTATCTGGATAATGAGAAACCTTATC
TGGCTGCTCGCGAAACCATTACAGGTAAAGAATTGTTGTTTGAATTTATGCTGAATACAACCCGGCTGGAACAATCCATA
CCTTTGGAGTTATTTACGACAGCGACAGGATTGGAACTGAATCAGCTTTTACCCTTACTGAAATTGGCTAATAAAAAACA
ATTAATTAATTTAACAGATACTCATTGGCAAGTAACACCATTAGGCAGGCAATATACTAATGATTTGCAAGCCTTGTTTC
TGCCCTAG

Upstream 100 bases:

>100_bases
ATTTTGGTTTATTTCGCATCAATGGTCATCACTTAATTTTGTAGCAAAATTGCTACCATGATACTATTGCATTCCCTAAC
AAGCCAGTTTAAAAATTGTA

Downstream 100 bases:

>100_bases
TTCACTGTTTCAAAAATTATTGATTCTTGCTTTATTGCAGAGAGTGGATTAGAGAAGGGGGGTTATATCCCCCCATTAAT
TGCTCAACGCGTTCTGCAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MLPLSLYIHIPWCIRKCPYCDFNSHKSPDVLPEHQYIQALIEDLKTDISSYNTREINSIFIGGGTPSLFSAEAYNNLFNE
LKRILPFAKNIEITMEANPGTVEQHRFTDYRQSGINRLSLGIQSFNPNHLKILGRIHDEKQAHSAIDTARKAGFDNLNLD
IMHSLPNQSITQGLEDLKTALSYQPEHLSWYQLTIEPNTVFYKHTPPLPSEEEDYLLEEQGFALLYNSGYHRYEISAFSK
PEKQARHNINYWLFGDYLGIGAGAHGKMTTPNAIIRTRKHRQPKDYLDNEKPYLAARETITGKELLFEFMLNTTRLEQSI
PLELFTTATGLELNQLLPLLKLANKKQLINLTDTHWQVTPLGRQYTNDLQALFLP

Sequences:

>Translated_375_residues
MLPLSLYIHIPWCIRKCPYCDFNSHKSPDVLPEHQYIQALIEDLKTDISSYNTREINSIFIGGGTPSLFSAEAYNNLFNE
LKRILPFAKNIEITMEANPGTVEQHRFTDYRQSGINRLSLGIQSFNPNHLKILGRIHDEKQAHSAIDTARKAGFDNLNLD
IMHSLPNQSITQGLEDLKTALSYQPEHLSWYQLTIEPNTVFYKHTPPLPSEEEDYLLEEQGFALLYNSGYHRYEISAFSK
PEKQARHNINYWLFGDYLGIGAGAHGKMTTPNAIIRTRKHRQPKDYLDNEKPYLAARETITGKELLFEFMLNTTRLEQSI
PLELFTTATGLELNQLLPLLKLANKKQLINLTDTHWQVTPLGRQYTNDLQALFLP
>Mature_375_residues
MLPLSLYIHIPWCIRKCPYCDFNSHKSPDVLPEHQYIQALIEDLKTDISSYNTREINSIFIGGGTPSLFSAEAYNNLFNE
LKRILPFAKNIEITMEANPGTVEQHRFTDYRQSGINRLSLGIQSFNPNHLKILGRIHDEKQAHSAIDTARKAGFDNLNLD
IMHSLPNQSITQGLEDLKTALSYQPEHLSWYQLTIEPNTVFYKHTPPLPSEEEDYLLEEQGFALLYNSGYHRYEISAFSK
PEKQARHNINYWLFGDYLGIGAGAHGKMTTPNAIIRTRKHRQPKDYLDNEKPYLAARETITGKELLFEFMLNTTRLEQSI
PLELFTTATGLELNQLLPLLKLANKKQLINLTDTHWQVTPLGRQYTNDLQALFLP

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=281, Percent_Identity=33.0960854092527, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1789325, Length=373, Percent_Identity=47.1849865951743, Blast_Score=363, Evalue=1e-102,
Organism=Escherichia coli, GI87082341, Length=395, Percent_Identity=25.3164556962025, Blast_Score=121, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 43117; Mature: 43117

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLSLYIHIPWCIRKCPYCDFNSHKSPDVLPEHQYIQALIEDLKTDISSYNTREINSIF
CCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEE
IGGGTPSLFSAEAYNNLFNELKRILPFAKNIEITMEANPGTVEQHRFTDYRQSGINRLSL
ECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEE
GIQSFNPNHLKILGRIHDEKQAHSAIDTARKAGFDNLNLDIMHSLPNQSITQGLEDLKTA
EHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHH
LSYQPEHLSWYQLTIEPNTVFYKHTPPLPSEEEDYLLEEQGFALLYNSGYHRYEISAFSK
HCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCEECCCCEEEEECCCCCEEEECCCCC
PEKQARHNINYWLFGDYLGIGAGAHGKMTTPNAIIRTRKHRQPKDYLDNEKPYLAARETI
CHHHHHCCCCEEEEECEEEECCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCEEEHHCC
TGKELLFEFMLNTTRLEQSIPLELFTTATGLELNQLLPLLKLANKKQLINLTDTHWQVTP
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCEEEEE
LGRQYTNDLQALFLP
CCHHHHCCCCEEECC
>Mature Secondary Structure
MLPLSLYIHIPWCIRKCPYCDFNSHKSPDVLPEHQYIQALIEDLKTDISSYNTREINSIF
CCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEE
IGGGTPSLFSAEAYNNLFNELKRILPFAKNIEITMEANPGTVEQHRFTDYRQSGINRLSL
ECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEE
GIQSFNPNHLKILGRIHDEKQAHSAIDTARKAGFDNLNLDIMHSLPNQSITQGLEDLKTA
EHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHH
LSYQPEHLSWYQLTIEPNTVFYKHTPPLPSEEEDYLLEEQGFALLYNSGYHRYEISAFSK
HCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCEECCCCEEEEECCCCCEEEECCCCC
PEKQARHNINYWLFGDYLGIGAGAHGKMTTPNAIIRTRKHRQPKDYLDNEKPYLAARETI
CHHHHHCCCCEEEEECEEEECCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCEEEHHCC
TGKELLFEFMLNTTRLEQSIPLELFTTATGLELNQLLPLLKLANKKQLINLTDTHWQVTP
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCEEEEE
LGRQYTNDLQALFLP
CCHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]