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The map label for this gene is motA2 [H]

Identifier: 54295158

GI number: 54295158

Start: 2555344

End: 2556249

Strand: Direct

Name: motA2 [H]

Synonym: lpl2238

Alternate gene names: 54295158

Gene position: 2555344-2556249 (Clockwise)

Preceding gene: 54295157

Following gene: 54295159

Centisome position: 76.38

GC content: 39.07

Gene sequence:

>906_bases
ATGTTAATTATAGTAGGTTATATTGTAATACTACTCTGTGTATTTGGTGGGTTCAGCCTGACAGGCGGTCATCTCGCCGC
TATATTTCAGCCGGTTGAATTATTGATAATCGGAGGGGCCGCCATAGGTTCCTTTATCGTTGGTAATAATATTACCGTTT
TAAAATCTGTTCTAAAATCTCTGCCTGCTACATTTCGCGGCCAAAAATCGGCAAAGCAAGCCTCCAGTGATTTGTTAAGC
CTTCTATACCATTTACTCAGTAAAGCAAGGCAACAAGGGTTAATGTCGCTCGAAAATGACATTGACGAGCCGGATAAAAG
CCCAATTTTTACCAATTATCCCAATTTAATGAGTAATCATCATTTAATAGAGTTTATTTGTGATTACCTGAGATTGATTA
TTACTTCCAACATGCAGCCTTTTCAATTGGAAAGCTTGATGGATATGGAGATCGAATCTCACCATGAAGAAGAAATGATA
CCGGCCAATGCCATCACCAAACTGGCTGATGCCATGCCTGCTTTTGGTATCGTCGCAGCAGTACTAGGTGTTGTCCATAC
CATGGAATCCATCAGCTTACCTCCCTCTGAATTAGGTGTTTTAATCGCTCATGCATTAGTAGGAACCTTTTTAGGTATTT
TAATTGGCTATGGTTTTGTTGGACCTATCGCTACTGCTATGGAACAAAATGCCAATCAAAATCAACTGATGCTGCAATGT
ATAAAAGTTACCATCCTGGCAAGTTTGCACAATAACCCTCCTATTATTGCTACTGAATTTGGACGTAAAGTATTATTTAC
ATCGCAAAGACCTTCATTTAACCAATTAAATGATGAAATAAAAAATGCCAAAACCGCTCAGACAACAACTCAAAACTCTG
AAGCAACAGAAGCTACGTCCACTTAG

Upstream 100 bases:

>100_bases
TCCCAATGACTGAAGGTATAGCACTGTATGACATGTCTGCCAAAGACACTATGAAAAAATATCAAGACTAATTGGACACC
AGATACTATAGGATAGGGAT

Downstream 100 bases:

>100_bases
GTTACAGCCATGAGCGAAATAAACGACATCAGCGATCCGATCAACGACGATCTGGAAAAAAGGGACAAGCGGGAAAAAAA
AGAAAAAACCACTCACTATA

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAIGSFIVGNNITVLKSVLKSLPATFRGQKSAKQASSDLLS
LLYHLLSKARQQGLMSLENDIDEPDKSPIFTNYPNLMSNHHLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMI
PANAITKLADAMPAFGIVAAVLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATST

Sequences:

>Translated_301_residues
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAIGSFIVGNNITVLKSVLKSLPATFRGQKSAKQASSDLLS
LLYHLLSKARQQGLMSLENDIDEPDKSPIFTNYPNLMSNHHLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMI
PANAITKLADAMPAFGIVAAVLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATST
>Mature_301_residues
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAIGSFIVGNNITVLKSVLKSLPATFRGQKSAKQASSDLLS
LLYHLLSKARQQGLMSLENDIDEPDKSPIFTNYPNLMSNHHLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMI
PANAITKLADAMPAFGIVAAVLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATST

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=295, Percent_Identity=52.2033898305085, Blast_Score=336, Evalue=1e-93,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 32603; Mature: 32603

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAIGSFIVGNNITVLKSVLKS
CEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCHHHHHHHHCCCHHHHHHHHHH
LPATFRGQKSAKQASSDLLSLLYHLLSKARQQGLMSLENDIDEPDKSPIFTNYPNLMSNH
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
HLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMIPANAITKLADAMPAFGIVAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHCCHHHHHHH
VLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATS
HHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCC
T
C
>Mature Secondary Structure
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAIGSFIVGNNITVLKSVLKS
CEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCHHHHHHHHCCCHHHHHHHHHH
LPATFRGQKSAKQASSDLLSLLYHLLSKARQQGLMSLENDIDEPDKSPIFTNYPNLMSNH
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
HLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMIPANAITKLADAMPAFGIVAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHCCHHHHHHH
VLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATS
HHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]