| Definition | Legionella pneumophila str. Lens, complete genome. |
|---|---|
| Accession | NC_006369 |
| Length | 3,345,687 |
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The map label for this gene is fabG [H]
Identifier: 54294991
GI number: 54294991
Start: 2331926
End: 2332690
Strand: Direct
Name: fabG [H]
Synonym: lpl2070
Alternate gene names: 54294991
Gene position: 2331926-2332690 (Clockwise)
Preceding gene: 54294988
Following gene: 54294993
Centisome position: 69.7
GC content: 38.43
Gene sequence:
>765_bases ATGTTCAATCAAAATTTAGCTATTATTATTGGCGGCTCTAGTGGTATGGGCCTTGAAACTGCAAAAAAACTTTCAAGTAA CAATATGGAGCTGTTAATTACCGGAAAAGATAAACAAAAACTTGAAAATGCTGCGGCAGAAATACAAAAACTGGGAGCAA AAGTAGATATTTTAGTTCTTGATCTTTATGACAAAGAGCAGGTATTCCAATTTATGAGCAGTATGAATGATGAAACTCGA AGAGTAAAATATCTTGTAAATGCCGCAGGTTATTTCAAACCCATCACTTTTTTAGAACATGAGGAAGAAGATTACGATCG TCAGGTTAATCTTAATAAGGCGTTCTTTTTTATCACCCAGGCCGTAGTAAAAAACATGAAAAAAAATGGAGGGGGTAGTA TCGTCAATATCGGTTCGATGTGGGCGAATCAGGCGGTTAAAGCAACCCCCTCCTCTGCTTATTCCATGCAAAAAGCCGGA CTTCATTCACTAACCCAACATTTAGCTATGGAGCTTGCTGAGCACAATATAAGAGTAAATGCCGTGGCGCCGGCAGTGGT AGCCACTCCTATCTATAAATCATTTATTGATGAAGAGAGAATCGAGGAGTCGTTAAAGGATTTTAATAAATTTCATCCTA TCGGCAGAATCGGTAAGGCAACAGATATCGCTGATGCAATCGAATTTCTTTTGTCAGAAAAAGCAAGCTGGATTACAGGG GAGATTATGAATGTTGATGGTGGCGTAATGGCAGGAAGAAATTAA
Upstream 100 bases:
>100_bases TACCATAAAGTACTTAGTGAACTGAAAAGTGCTTACTTTTTTTAATATTGTAGTTCTTTCATACTGGATTGGACAGTATT TTAATGAATCAGGAGAATCC
Downstream 100 bases:
>100_bases TCAGCAAACCTTATCCAGATTTATGCCTGCGAGCATCAATAGCAAAAGATTGATTTTTAATGCCCTGTTTCAGATTTATC TGATGTGGGCTCTGGATAAA
Product: hypothetical protein
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 254; Mature: 254
Protein sequence:
>254_residues MFNQNLAIIIGGSSGMGLETAKKLSSNNMELLITGKDKQKLENAAAEIQKLGAKVDILVLDLYDKEQVFQFMSSMNDETR RVKYLVNAAGYFKPITFLEHEEEDYDRQVNLNKAFFFITQAVVKNMKKNGGGSIVNIGSMWANQAVKATPSSAYSMQKAG LHSLTQHLAMELAEHNIRVNAVAPAVVATPIYKSFIDEERIEESLKDFNKFHPIGRIGKATDIADAIEFLLSEKASWITG EIMNVDGGVMAGRN
Sequences:
>Translated_254_residues MFNQNLAIIIGGSSGMGLETAKKLSSNNMELLITGKDKQKLENAAAEIQKLGAKVDILVLDLYDKEQVFQFMSSMNDETR RVKYLVNAAGYFKPITFLEHEEEDYDRQVNLNKAFFFITQAVVKNMKKNGGGSIVNIGSMWANQAVKATPSSAYSMQKAG LHSLTQHLAMELAEHNIRVNAVAPAVVATPIYKSFIDEERIEESLKDFNKFHPIGRIGKATDIADAIEFLLSEKASWITG EIMNVDGGVMAGRN >Mature_254_residues MFNQNLAIIIGGSSGMGLETAKKLSSNNMELLITGKDKQKLENAAAEIQKLGAKVDILVLDLYDKEQVFQFMSSMNDETR RVKYLVNAAGYFKPITFLEHEEEDYDRQVNLNKAFFFITQAVVKNMKKNGGGSIVNIGSMWANQAVKATPSSAYSMQKAG LHSLTQHLAMELAEHNIRVNAVAPAVVATPIYKSFIDEERIEESLKDFNKFHPIGRIGKATDIADAIEFLLSEKASWITG EIMNVDGGVMAGRN
Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.5301204819277, Blast_Score=118, Evalue=4e-27, Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=31.0204081632653, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=29.2682926829268, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=28.740157480315, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI66933014, Length=192, Percent_Identity=32.2916666666667, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI15277342, Length=174, Percent_Identity=33.9080459770115, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=30, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=29.0322580645161, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=25.6916996047431, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=25, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=26.9430051813472, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=28.042328042328, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=25.1336898395722, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=26.6409266409266, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4503301, Length=228, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI59889578, Length=209, Percent_Identity=25.8373205741627, Blast_Score=64, Evalue=9e-11, Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=32.295719844358, Blast_Score=117, Evalue=8e-28, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=32.5301204819277, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=30, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=31.6, Blast_Score=108, Evalue=5e-25, Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=29.1497975708502, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=30.952380952381, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=26.1224489795918, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1786812, Length=204, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=28.4552845528455, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=25.4901960784314, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=25.8823529411765, Blast_Score=71, Evalue=8e-14, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=33.4677419354839, Blast_Score=126, Evalue=1e-29, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=32.5301204819277, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=30.7984790874525, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=29.0836653386454, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=30.6513409961686, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17561402, Length=264, Percent_Identity=28.4090909090909, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.1666666666667, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=30.4832713754647, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=31.0606060606061, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=28.735632183908, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=31.1787072243346, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17563726, Length=257, Percent_Identity=30.7392996108949, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=27.4900398406374, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=25.296442687747, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=30.5660377358491, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=26.0536398467433, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=29.277566539924, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=29.7709923664122, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=29.6992481203008, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=25.0996015936255, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=28.6852589641434, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=27.2030651340996, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=28.5185185185185, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=25.5639097744361, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=26.0377358490566, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=27.7566539923954, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=25.5905511811024, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=26.4, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17561272, Length=214, Percent_Identity=26.6355140186916, Blast_Score=69, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=26.4591439688716, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=250, Percent_Identity=27.6, Blast_Score=68, Evalue=2e-12, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=32.6693227091633, Blast_Score=116, Evalue=2e-26, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=30.2788844621514, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=31.4741035856574, Blast_Score=111, Evalue=5e-25, Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=31.0756972111554, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=28.6290322580645, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=28.1124497991968, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24644337, Length=177, Percent_Identity=35.5932203389831, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=30.5220883534137, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI17737361, Length=262, Percent_Identity=24.4274809160305, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24584752, Length=194, Percent_Identity=29.3814432989691, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI21356301, Length=202, Percent_Identity=28.2178217821782, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 28097; Mature: 28097
Theoretical pI: Translated: 6.37; Mature: 6.37
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 4.3 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 4.3 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFNQNLAIIIGGSSGMGLETAKKLSSNNMELLITGKDKQKLENAAAEIQKLGAKVDILVL CCCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEE DLYDKEQVFQFMSSMNDETRRVKYLVNAAGYFKPITFLEHEEEDYDRQVNLNKAFFFITQ EECCHHHHHHHHHHCCHHHHHHHHHHHHHCHHCCHHHHCCCCHHHHHCCCCHHHHHHHHH AVVKNMKKNGGGSIVNIGSMWANQAVKATPSSAYSMQKAGLHSLTQHLAMELAEHNIRVN HHHHHHHCCCCCCEEEECHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEE AVAPAVVATPIYKSFIDEERIEESLKDFNKFHPIGRIGKATDIADAIEFLLSEKASWITG EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCC EIMNVDGGVMAGRN EEEECCCCEECCCC >Mature Secondary Structure MFNQNLAIIIGGSSGMGLETAKKLSSNNMELLITGKDKQKLENAAAEIQKLGAKVDILVL CCCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEE DLYDKEQVFQFMSSMNDETRRVKYLVNAAGYFKPITFLEHEEEDYDRQVNLNKAFFFITQ EECCHHHHHHHHHHCCHHHHHHHHHHHHHCHHCCHHHHCCCCHHHHHCCCCHHHHHHHHH AVVKNMKKNGGGSIVNIGSMWANQAVKATPSSAYSMQKAGLHSLTQHLAMELAEHNIRVN HHHHHHHCCCCCCEEEECHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEE AVAPAVVATPIYKSFIDEERIEESLKDFNKFHPIGRIGKATDIADAIEFLLSEKASWITG EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCC EIMNVDGGVMAGRN EEEECCCCEECCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]