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The map label for this gene is recG [H]

Identifier: 54294931

GI number: 54294931

Start: 2253628

End: 2255700

Strand: Direct

Name: recG [H]

Synonym: lpl2010

Alternate gene names: 54294931

Gene position: 2253628-2255700 (Clockwise)

Preceding gene: 54294927

Following gene: 54294933

Centisome position: 67.36

GC content: 40.81

Gene sequence:

>2073_bases
GTGCTGAGTAACTCTTGTGAATATTTAACTGGCGTCGGCCCAACCATTGCAGCAAAACTTGCTAAATGTGGAATTTTCAC
GATACAAGACTTGCTTTTCCACCTGCCTTATAAATATCAGGACAGAACCAGGATAACACCAATTCAGGATTTGCGCTCCA
ATGAATGGTGCGTTATCGCGGGGCATGTATGCAAAACTGAAATAAAATACGGCAAAAGGATGATGTTGAATTGTTATGTG
GAAGATAAAACAGGAGTAGTTAAGCTTCGTTTTTTTCATTTCAATAAGCAGCAAATTCAGGCCTTGAATAATAGCGCCAT
GATTCGAGCTTTTGGCGAAGTCCGCGGATTTAACAACCAGTTGGAGATGATTCATCCAGAATATCAATTAATTAACCAAG
AATCAGATTTCCACGTAGAAGAAACGCTTACGCCAATTTATCCATCAACTCAAGGCTTGACTCAAACCCGATTAAGGCAG
TTAGTTAAAATAGCCCTGGAACAATCTGAACACGAACTTCATCAATTGGAATGGATGAGTGAAAAACAATTACAGGAAAA
CAATTTTTATGATTTGGGCGAAGCCATTAAATTACTGCATAACCCCCCGCCAGATATCTCCCTCTCCAACCTCGAAGCCG
GCGAACATCCTGCTCTCAAGCGGTTAATATTTGATGAATTATTGGCACAACAGCTCAGTATGCAATTTGCAAGACAGTCA
CGTAGCAAGCTCCAGGCTCCCGCTATATTTTTCGATAATGCAATTCATAAACGTTTTATCGAATCATTGCCATTCAGTCT
TACAAACGCACAACAACGGGTTTTTAAAGAAATCAGCGTTGATTTAACTCAAAGCAAACCCATGCTTCGTTTGCTGCAAG
GAGATGTTGGGGCGGGTAAAACCATTATCGCGGCACTAGCCGCCCTTCAAGCCATTTCACAAGGATTTCAGGTTGCTTTT
ATGGCACCAACCGATTTATTAAGTGAACAACATACAAATAGCCTTGGTAAATGGTTAGAACCTATCGGTATTAATGTATT
AAGACTGAGCGGTAAAATGAAAACCACAGAACGAAAAAATGCGCTTGCAGCCCTGCAGGACAATAGCTGTAAGCTCATTG
TTGGAACTCATGCCTTATTTCAGGAGCAAGTCGAATTCGCTCGTTTGGGTTTGGTCATTATTGACGAACAACACCGATTC
GGAGTAGAACAACGGCTCCTTCTACAACAAAAAGGGCAATTAAACCAATTAATCCCTCATCAATTATTAATGACAGCCAC
CCCTATTCCAAGAACCCTGTCAATGTCTCATTTTGCCCATTTGGATATATCGGTCATCGATGAACTACCGCCTGGCCGTA
TGCCAATTACAACAGCAGTATTAAACCAGGATAAGCGTGAACTCATTATCGAACGTTTGCAAGCAGCAATCTCCAACGGC
AAACAAGCTTACTGGGTCTGTACCCTTATAGAAGAATCTGAAAAATTACAATGCATGGCAGCAACAGATACCTCAAAAAA
ACTACAAGAACAGCTCTCTTTCGCGCGTGTTGGTCTTGTTCATGGGAGAATGAAAGCATTTGAAAAAGAAGCTACTATGG
CAGCCTTTAAACAAGGCGAGATTGATTTATTGGTGGCAACTACTGTTATTGAAGTTGGTGTAGATGTTCCCAATGCCAGT
TTAATGATCATTGAAAATGCAGAGCGACTTGGTTTGTCGCAGTTACATCAATTACGAGGGCGCGTAGGCAGAGGTAATAA
TCAATCTCATTGTCTATTACTTTATCAATCTCCTCTATCACAACAAGGTGCTGAACGTCTCAAGATCATGCGTTCAACAA
CAGACGGTTTTCTAATCTCCGAAAAGGATCTGGAGTTAAGAGGCTCAGGAGAAATATTAGGAACCAAACAGACTGGCTTT
AGACAATTTAAAATAGCTAACTTACAACGCGATAAAACCCTCTTCACTATTTTACGTCCAATTGCAAAACAACTGGTGCT
GGAAAAAACAGCAATCGCCAGACAAATTACACAACGATGGCTGGGCAATTTTGAACAATTTTTGCAAAGTTAA

Upstream 100 bases:

>100_bases
TAACTTAGTAATGATTTGGGCAAAATTGCCAGAATGATGACTCAAGTCGCAACGAATATATTTTCCTGTTATTATTAAAT
TTTTAATCTTAAATAATACC

Downstream 100 bases:

>100_bases
AAAAATAATTAAAATTATTGAAGTCAAGACTGTTTTTTATTTTTTTCTTTGCTAACATAAGCGGACCACAAGTAAAATTC
ATTACCTCTTATCCCTGTGG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MLSNSCEYLTGVGPTIAAKLAKCGIFTIQDLLFHLPYKYQDRTRITPIQDLRSNEWCVIAGHVCKTEIKYGKRMMLNCYV
EDKTGVVKLRFFHFNKQQIQALNNSAMIRAFGEVRGFNNQLEMIHPEYQLINQESDFHVEETLTPIYPSTQGLTQTRLRQ
LVKIALEQSEHELHQLEWMSEKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQS
RSKLQAPAIFFDNAIHKRFIESLPFSLTNAQQRVFKEISVDLTQSKPMLRLLQGDVGAGKTIIAALAALQAISQGFQVAF
MAPTDLLSEQHTNSLGKWLEPIGINVLRLSGKMKTTERKNALAALQDNSCKLIVGTHALFQEQVEFARLGLVIIDEQHRF
GVEQRLLLQQKGQLNQLIPHQLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAISNG
KQAYWVCTLIEESEKLQCMAATDTSKKLQEQLSFARVGLVHGRMKAFEKEATMAAFKQGEIDLLVATTVIEVGVDVPNAS
LMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLSQQGAERLKIMRSTTDGFLISEKDLELRGSGEILGTKQTGF
RQFKIANLQRDKTLFTILRPIAKQLVLEKTAIARQITQRWLGNFEQFLQS

Sequences:

>Translated_690_residues
MLSNSCEYLTGVGPTIAAKLAKCGIFTIQDLLFHLPYKYQDRTRITPIQDLRSNEWCVIAGHVCKTEIKYGKRMMLNCYV
EDKTGVVKLRFFHFNKQQIQALNNSAMIRAFGEVRGFNNQLEMIHPEYQLINQESDFHVEETLTPIYPSTQGLTQTRLRQ
LVKIALEQSEHELHQLEWMSEKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQS
RSKLQAPAIFFDNAIHKRFIESLPFSLTNAQQRVFKEISVDLTQSKPMLRLLQGDVGAGKTIIAALAALQAISQGFQVAF
MAPTDLLSEQHTNSLGKWLEPIGINVLRLSGKMKTTERKNALAALQDNSCKLIVGTHALFQEQVEFARLGLVIIDEQHRF
GVEQRLLLQQKGQLNQLIPHQLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAISNG
KQAYWVCTLIEESEKLQCMAATDTSKKLQEQLSFARVGLVHGRMKAFEKEATMAAFKQGEIDLLVATTVIEVGVDVPNAS
LMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLSQQGAERLKIMRSTTDGFLISEKDLELRGSGEILGTKQTGF
RQFKIANLQRDKTLFTILRPIAKQLVLEKTAIARQITQRWLGNFEQFLQS
>Mature_690_residues
MLSNSCEYLTGVGPTIAAKLAKCGIFTIQDLLFHLPYKYQDRTRITPIQDLRSNEWCVIAGHVCKTEIKYGKRMMLNCYV
EDKTGVVKLRFFHFNKQQIQALNNSAMIRAFGEVRGFNNQLEMIHPEYQLINQESDFHVEETLTPIYPSTQGLTQTRLRQ
LVKIALEQSEHELHQLEWMSEKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQS
RSKLQAPAIFFDNAIHKRFIESLPFSLTNAQQRVFKEISVDLTQSKPMLRLLQGDVGAGKTIIAALAALQAISQGFQVAF
MAPTDLLSEQHTNSLGKWLEPIGINVLRLSGKMKTTERKNALAALQDNSCKLIVGTHALFQEQVEFARLGLVIIDEQHRF
GVEQRLLLQQKGQLNQLIPHQLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAISNG
KQAYWVCTLIEESEKLQCMAATDTSKKLQEQLSFARVGLVHGRMKAFEKEATMAAFKQGEIDLLVATTVIEVGVDVPNAS
LMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLSQQGAERLKIMRSTTDGFLISEKDLELRGSGEILGTKQTGF
RQFKIANLQRDKTLFTILRPIAKQLVLEKTAIARQITQRWLGNFEQFLQS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=680, Percent_Identity=50, Blast_Score=656, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=404, Percent_Identity=35.3960396039604, Blast_Score=234, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78064; Mature: 78064

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSNSCEYLTGVGPTIAAKLAKCGIFTIQDLLFHLPYKYQDRTRITPIQDLRSNEWCVIA
CCCCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEEE
GHVCKTEIKYGKRMMLNCYVEDKTGVVKLRFFHFNKQQIQALNNSAMIRAFGEVRGFNNQ
CCHHHHHHHHCCEEEEEEEEECCCCEEEEEEEECCHHHHHHHCCCHHHHHHHHHCCCCCC
LEMIHPEYQLINQESDFHVEETLTPIYPSTQGLTQTRLRQLVKIALEQSEHELHQLEWMS
CEEECCHHHHHCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQS
HHHHHCCCCCCHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RSKLQAPAIFFDNAIHKRFIESLPFSLTNAQQRVFKEISVDLTQSKPMLRLLQGDVGAGK
HHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCH
TIIAALAALQAISQGFQVAFMAPTDLLSEQHTNSLGKWLEPIGINVLRLSGKMKTTERKN
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHH
ALAALQDNSCKLIVGTHALFQEQVEFARLGLVIIDEQHRFGVEQRLLLQQKGQLNQLIPH
HHHEEECCCEEEEECCHHHHHHHHHHHHCCEEEEECHHHCCHHHHHHHHHCCCHHHHCHH
QLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAISNG
HHHHHCCCCCCCCCHHHHHCCCHHHHCCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHCC
KQAYWVCTLIEESEKLQCMAATDTSKKLQEQLSFARVGLVHGRMKAFEKEATMAAFKQGE
CEEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IDLLVATTVIEVGVDVPNASLMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLS
EEEEEEHHHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCC
QQGAERLKIMRSTTDGFLISEKDLELRGSGEILGTKQTGFRQFKIANLQRDKTLFTILRP
HHHHHHHHHHHCCCCCEEEECCCCEECCCCCEEECCCCCCEEEEECCCCCHHHHHHHHHH
IAKQLVLEKTAIARQITQRWLGNFEQFLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSNSCEYLTGVGPTIAAKLAKCGIFTIQDLLFHLPYKYQDRTRITPIQDLRSNEWCVIA
CCCCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEEE
GHVCKTEIKYGKRMMLNCYVEDKTGVVKLRFFHFNKQQIQALNNSAMIRAFGEVRGFNNQ
CCHHHHHHHHCCEEEEEEEEECCCCEEEEEEEECCHHHHHHHCCCHHHHHHHHHCCCCCC
LEMIHPEYQLINQESDFHVEETLTPIYPSTQGLTQTRLRQLVKIALEQSEHELHQLEWMS
CEEECCHHHHHCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQS
HHHHHCCCCCCHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RSKLQAPAIFFDNAIHKRFIESLPFSLTNAQQRVFKEISVDLTQSKPMLRLLQGDVGAGK
HHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCH
TIIAALAALQAISQGFQVAFMAPTDLLSEQHTNSLGKWLEPIGINVLRLSGKMKTTERKN
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHH
ALAALQDNSCKLIVGTHALFQEQVEFARLGLVIIDEQHRFGVEQRLLLQQKGQLNQLIPH
HHHEEECCCEEEEECCHHHHHHHHHHHHCCEEEEECHHHCCHHHHHHHHHCCCHHHHCHH
QLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAISNG
HHHHHCCCCCCCCCHHHHHCCCHHHHCCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHCC
KQAYWVCTLIEESEKLQCMAATDTSKKLQEQLSFARVGLVHGRMKAFEKEATMAAFKQGE
CEEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IDLLVATTVIEVGVDVPNASLMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLS
EEEEEEHHHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCC
QQGAERLKIMRSTTDGFLISEKDLELRGSGEILGTKQTGFRQFKIANLQRDKTLFTILRP
HHHHHHHHHHHCCCCCEEEECCCCEECCCCCEEECCCCCCEEEEECCCCCHHHHHHHHHH
IAKQLVLEKTAIARQITQRWLGNFEQFLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]