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The map label for this gene is pfp [H]

Identifier: 54294800

GI number: 54294800

Start: 2102901

End: 2104145

Strand: Direct

Name: pfp [H]

Synonym: lpl1877

Alternate gene names: 54294800

Gene position: 2102901-2104145 (Clockwise)

Preceding gene: 54294799

Following gene: 54294803

Centisome position: 62.85

GC content: 43.69

Gene sequence:

>1245_bases
ATGTCAGTTAAAAATGCAATCTACGCCCAGTCGGGTGGCGTGACCGCTGTAATTAATGCATCCGCTTGTGGTGTCATTCA
AACAGCCAAACTATTTCCAGAGCAAATTGGTAAAGTTTATGCTGCAAAAAATGGCATTATCGGTGCCTTAAACGAGGAAT
TAATCGATACTTCATTGGAAAGTGAAGAAGACATTGCCAAATTAATGCAAACTCCTTCCGGAGCTTTTGGCTCCTGCCGC
TACAAATTAAAAGACAATGGGGAAGAGTATCAACGCTTGATCGCTGTCTTCAAGGCGCACAACATAGGATATTTCTTTTA
CAATGGCGGCGGGGACTCACAAGATACTGCCCATAAAGTATCCCAGCTGGGTAAAACCATGGGCTATCCTATTACCTGCA
TAGGTATCCCTAAAACAGTAGATAACGATCTGCCTTTTACAGACAATTGCCCGGGGTTTGGATCAGTCGCGAAATACATT
GCCATTTCAACGAAGGAAGCTGGTTTTGATGTCGCGTCCATGGCAGCTTCATCCACGAAAGTGTTTATTCTTGAGGTGAT
GGGAAGGCATGCAGGCTGGATAGCTGCGGCTAGTGGGCTGGCCGAGCAAAATCCAGGCGAACCGCCACACATTATCCTAT
TGCCTGAAGTTCCTTTTGAGCCAACTCGTTTTCTAAAAAAAGTGAAAGACTGTGTCAATTCGTATGGTTATTGTGTGATT
GTTGTTTCAGAAGGTATCCGCAATAAGGAAGGAAAATTTCTCAGTGAAGCAGGATTACGCGATGCATTCGGACATGCCCA
ATTAGGTGGTGTTGCACCAGTCATCGCCCAATTGATTAAATCAGAACTTGGTTTTAAATACCATTGGGCAGTTGCAGATT
ATCTTCAACGGGCAGCCAGACACATAGCCTCGCAGGTTGATTTGGATCAAGCTTATGCTTTAGGTAAGGCTGCTGTGGAA
TATGCCGTAAAAGGATATAACGCGATAATGCCTATTGTTATTCGTGAACAAGACGAGCCTTATCAATGGTCCATAGGTCA
AGTCCCTCTGGCTGAGGTAGCTAACCAGGAAAAGTCTATGCCACCAGAGTATATAGCTGAAGATGGCATGGGAATTACGG
ACGCATGCAAACGTTACTTGTCCCCTTTGATTCAAGGTGAAGCTTATCCCAATTACAAAAATGGATTACCGGATTATGTC
CGACTAAAAAACCAGTTAGTGGCTAAAAAAATCAATCAAGATTAA

Upstream 100 bases:

>100_bases
TAACATGGGATGAAATAAGGCCATAAAAAACTCTCTTGTATGAAAACCAAAGTAAAAGTCTATATCAACCTAATAAAATC
ACTCTAGTTATGGAGACAAA

Downstream 100 bases:

>100_bases
GGGCGGCAGTAGGCTGGACGATATTTACTAATCAGGGTACCACCAGTGCAATCCCAAGTGAGTATTCTGCCTGTAGCGTC
TAATGTAGGAACCATTGTAA

Product: 6-phosphofructokinase

Products: NA

Alternate protein names: 6-phosphofructokinase, pyrophosphate dependent; PPi-dependent phosphofructokinase; PPi-PFK; Pyrophosphate-dependent 6-phosphofructose-1-kinase [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSVKNAIYAQSGGVTAVINASACGVIQTAKLFPEQIGKVYAAKNGIIGALNEELIDTSLESEEDIAKLMQTPSGAFGSCR
YKLKDNGEEYQRLIAVFKAHNIGYFFYNGGGDSQDTAHKVSQLGKTMGYPITCIGIPKTVDNDLPFTDNCPGFGSVAKYI
AISTKEAGFDVASMAASSTKVFILEVMGRHAGWIAAASGLAEQNPGEPPHIILLPEVPFEPTRFLKKVKDCVNSYGYCVI
VVSEGIRNKEGKFLSEAGLRDAFGHAQLGGVAPVIAQLIKSELGFKYHWAVADYLQRAARHIASQVDLDQAYALGKAAVE
YAVKGYNAIMPIVIREQDEPYQWSIGQVPLAEVANQEKSMPPEYIAEDGMGITDACKRYLSPLIQGEAYPNYKNGLPDYV
RLKNQLVAKKINQD

Sequences:

>Translated_414_residues
MSVKNAIYAQSGGVTAVINASACGVIQTAKLFPEQIGKVYAAKNGIIGALNEELIDTSLESEEDIAKLMQTPSGAFGSCR
YKLKDNGEEYQRLIAVFKAHNIGYFFYNGGGDSQDTAHKVSQLGKTMGYPITCIGIPKTVDNDLPFTDNCPGFGSVAKYI
AISTKEAGFDVASMAASSTKVFILEVMGRHAGWIAAASGLAEQNPGEPPHIILLPEVPFEPTRFLKKVKDCVNSYGYCVI
VVSEGIRNKEGKFLSEAGLRDAFGHAQLGGVAPVIAQLIKSELGFKYHWAVADYLQRAARHIASQVDLDQAYALGKAAVE
YAVKGYNAIMPIVIREQDEPYQWSIGQVPLAEVANQEKSMPPEYIAEDGMGITDACKRYLSPLIQGEAYPNYKNGLPDYV
RLKNQLVAKKINQD
>Mature_413_residues
SVKNAIYAQSGGVTAVINASACGVIQTAKLFPEQIGKVYAAKNGIIGALNEELIDTSLESEEDIAKLMQTPSGAFGSCRY
KLKDNGEEYQRLIAVFKAHNIGYFFYNGGGDSQDTAHKVSQLGKTMGYPITCIGIPKTVDNDLPFTDNCPGFGSVAKYIA
ISTKEAGFDVASMAASSTKVFILEVMGRHAGWIAAASGLAEQNPGEPPHIILLPEVPFEPTRFLKKVKDCVNSYGYCVIV
VSEGIRNKEGKFLSEAGLRDAFGHAQLGGVAPVIAQLIKSELGFKYHWAVADYLQRAARHIASQVDLDQAYALGKAAVEY
AVKGYNAIMPIVIREQDEPYQWSIGQVPLAEVANQEKSMPPEYIAEDGMGITDACKRYLSPLIQGEAYPNYKNGLPDYVR
LKNQLVAKKINQD

Specific function: Key control step of glycolysis. [C]

COG id: COG0205

COG function: function code G; 6-phosphofructokinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphofructokinase family [H]

Homologues:

Organism=Escherichia coli, GI1790350, Length=286, Percent_Identity=25.1748251748252, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 3981 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 950 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012003
- InterPro:   IPR012829
- InterPro:   IPR022953
- InterPro:   IPR015912
- InterPro:   IPR000023 [H]

Pfam domain/function: PF00365 PFK [H]

EC number: =2.7.1.90 [H]

Molecular weight: Translated: 44921; Mature: 44790

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKNAIYAQSGGVTAVINASACGVIQTAKLFPEQIGKVYAAKNGIIGALNEELIDTSLE
CCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCC
SEEDIAKLMQTPSGAFGSCRYKLKDNGEEYQRLIAVFKAHNIGYFFYNGGGDSQDTAHKV
CHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
SQLGKTMGYPITCIGIPKTVDNDLPFTDNCPGFGSVAKYIAISTKEAGFDVASMAASSTK
HHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCHHHHHCCCCC
VFILEVMGRHAGWIAAASGLAEQNPGEPPHIILLPEVPFEPTRFLKKVKDCVNSYGYCVI
EEEEEHHCCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEE
VVSEGIRNKEGKFLSEAGLRDAFGHAQLGGVAPVIAQLIKSELGFKYHWAVADYLQRAAR
EEECCCCCCCCCHHHHCCCHHHCCCHHHCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
HIASQVDLDQAYALGKAAVEYAVKGYNAIMPIVIREQDEPYQWSIGQVPLAEVANQEKSM
HHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCCCCHHHHHCHHCCC
PPEYIAEDGMGITDACKRYLSPLIQGEAYPNYKNGLPDYVRLKNQLVAKKINQD
CHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVKNAIYAQSGGVTAVINASACGVIQTAKLFPEQIGKVYAAKNGIIGALNEELIDTSLE
CCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCC
SEEDIAKLMQTPSGAFGSCRYKLKDNGEEYQRLIAVFKAHNIGYFFYNGGGDSQDTAHKV
CHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
SQLGKTMGYPITCIGIPKTVDNDLPFTDNCPGFGSVAKYIAISTKEAGFDVASMAASSTK
HHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCHHHHHCCCCC
VFILEVMGRHAGWIAAASGLAEQNPGEPPHIILLPEVPFEPTRFLKKVKDCVNSYGYCVI
EEEEEHHCCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEE
VVSEGIRNKEGKFLSEAGLRDAFGHAQLGGVAPVIAQLIKSELGFKYHWAVADYLQRAAR
EEECCCCCCCCCHHHHCCCHHHCCCHHHCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
HIASQVDLDQAYALGKAAVEYAVKGYNAIMPIVIREQDEPYQWSIGQVPLAEVANQEKSM
HHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCCCCHHHHHCHHCCC
PPEYIAEDGMGITDACKRYLSPLIQGEAYPNYKNGLPDYVRLKNQLVAKKINQD
CHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10913106 [H]