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The map label for this gene is eriC [C]

Identifier: 54294779

GI number: 54294779

Start: 2077220

End: 2078500

Strand: Direct

Name: eriC [C]

Synonym: lpl1856

Alternate gene names: 54294779

Gene position: 2077220-2078500 (Clockwise)

Preceding gene: 54294777

Following gene: 54294782

Centisome position: 62.09

GC content: 41.92

Gene sequence:

>1281_bases
ATGGAGTTAACCACAACCGAGAACCAACTATTTAAAAGTTCCAAAGTAAGTCTTGCTCTGGTTACTGTTCTGGTAGGAAT
CGGTTCAGGTTTTCTAGGCATGTGCCTGGCCATGTTATTGCATTATCTTCAACATATTGCCTATGGTTACAGCCCCCTTC
ACATCATCAGTAATGAAACTTTTCTGGAGGGAGTTAGAGCCTCTTCATCTGAGCGGAGAATAAGCATACTATTCCTTTGT
GGCTTAATTGCAGGTATAGGCTGGTGGGCACTTTATCGCTTTGGTGAACCATTAGTCAGTATTGCGGCGGCAATAAAATC
GGGTAAACCAATGCCGGCTCTCAGTACATTCATTCATGCTTTTTTACAAATCATAACAATTGCATTGGGCTCACCTCTGG
GACGAGAGGTGGCTCCTCGTGAGGTAAGCTCTGTCTTTGCTTACTGGCTATCTAGCAAAGCGGGATTAACTCCTGAGGAA
AGCAAGATCATGTTGGCATGTGGAGCAGGCGCGGGGCTTGCTGCAGTTTATAATGTGCCTTTAGGCGGCGCCGTTTTTGT
TTTGGAAGTGTTGTTATGCACTTCCAACTGGACTGTCTTGCTTCCTGCATTATCTTCTTCTGCTATAGCAGTTCTGGTGT
CTTGGTGGGGTTTGGGAAATGAATCAATTTATCAACTCCCTGAATTTTCATTAAGTGCACCTATAATTCTTTGGTCTATT
CTTGCCAGCCCGGTGTTAGGTTTTTTTGCTTTTTGGTTTATTCAAATTGCTACAATACAACGCAGCAAAGCAATGCATAA
CTGGCAAATAACATTGGCTTGTTTAATTAATTTTTTAATCATTGGCTTATTCGCAATTTATTTTCCTTCTTTACTAGGTA
ACGGCAAAAGTCCGGCAGAAATGGAGTTTGATCAATCAGTAGGAATTGGTTTAAGTATTGTATTATTTATGTTGAGGAAT
GTATTCGTATGGTCAAGCTTGCGTGTAGGAGCACAAGGTGGCTTACTAACCCCCTCACTGGCTAACGGCGCCTTATTAGG
AGCTATTCTAGGTGGAATTTGGAATTTGTATTTACCACCCGCTCCCATCCATGCCTTCGCGCTTATTGGTGCCACGGCTT
TTCTTGCTGCGGCACAAAAAATGCCTTTGACTGCCATTATCCTCATTTTCGAATTCACCCGGATTAATTTTATCTTTCTT
ATCCCTATCATGCTTGCTGTTTCCGGCTCTATAGGTATGTGCCAGTTAACCAAGAACTATTATATTAAATATAAAGTATG
A

Upstream 100 bases:

>100_bases
TTAATCTGTTTCACTTGCAAAAAAATCTGCATACAGAAATAATAAAATTCTTACCCCTATAAGCAAATTGATGACAAGTT
ACCTTAAAGGAATCCAGGGA

Downstream 100 bases:

>100_bases
TTCTTTGTAACAAGTATTTTTCATTGGCTGCACTGTAATATCCCTTATCAGTTCCAACATTATTTATTGATACACCACCA
AAAAGCTCCTGGTGGCATTC

Product: hypothetical protein

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MELTTTENQLFKSSKVSLALVTVLVGIGSGFLGMCLAMLLHYLQHIAYGYSPLHIISNETFLEGVRASSSERRISILFLC
GLIAGIGWWALYRFGEPLVSIAAAIKSGKPMPALSTFIHAFLQIITIALGSPLGREVAPREVSSVFAYWLSSKAGLTPEE
SKIMLACGAGAGLAAVYNVPLGGAVFVLEVLLCTSNWTVLLPALSSSAIAVLVSWWGLGNESIYQLPEFSLSAPIILWSI
LASPVLGFFAFWFIQIATIQRSKAMHNWQITLACLINFLIIGLFAIYFPSLLGNGKSPAEMEFDQSVGIGLSIVLFMLRN
VFVWSSLRVGAQGGLLTPSLANGALLGAILGGIWNLYLPPAPIHAFALIGATAFLAAAQKMPLTAIILIFEFTRINFIFL
IPIMLAVSGSIGMCQLTKNYYIKYKV

Sequences:

>Translated_426_residues
MELTTTENQLFKSSKVSLALVTVLVGIGSGFLGMCLAMLLHYLQHIAYGYSPLHIISNETFLEGVRASSSERRISILFLC
GLIAGIGWWALYRFGEPLVSIAAAIKSGKPMPALSTFIHAFLQIITIALGSPLGREVAPREVSSVFAYWLSSKAGLTPEE
SKIMLACGAGAGLAAVYNVPLGGAVFVLEVLLCTSNWTVLLPALSSSAIAVLVSWWGLGNESIYQLPEFSLSAPIILWSI
LASPVLGFFAFWFIQIATIQRSKAMHNWQITLACLINFLIIGLFAIYFPSLLGNGKSPAEMEFDQSVGIGLSIVLFMLRN
VFVWSSLRVGAQGGLLTPSLANGALLGAILGGIWNLYLPPAPIHAFALIGATAFLAAAQKMPLTAIILIFEFTRINFIFL
IPIMLAVSGSIGMCQLTKNYYIKYKV
>Mature_426_residues
MELTTTENQLFKSSKVSLALVTVLVGIGSGFLGMCLAMLLHYLQHIAYGYSPLHIISNETFLEGVRASSSERRISILFLC
GLIAGIGWWALYRFGEPLVSIAAAIKSGKPMPALSTFIHAFLQIITIALGSPLGREVAPREVSSVFAYWLSSKAGLTPEE
SKIMLACGAGAGLAAVYNVPLGGAVFVLEVLLCTSNWTVLLPALSSSAIAVLVSWWGLGNESIYQLPEFSLSAPIILWSI
LASPVLGFFAFWFIQIATIQRSKAMHNWQITLACLINFLIIGLFAIYFPSLLGNGKSPAEMEFDQSVGIGLSIVLFMLRN
VFVWSSLRVGAQGGLLTPSLANGALLGAILGGIWNLYLPPAPIHAFALIGATAFLAAAQKMPLTAIILIFEFTRINFIFL
IPIMLAVSGSIGMCQLTKNYYIKYKV

Specific function: Selective chloride channel [C]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 45934; Mature: 45934

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTTTENQLFKSSKVSLALVTVLVGIGSGFLGMCLAMLLHYLQHIAYGYSPLHIISNET
CCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCH
FLEGVRASSSERRISILFLCGLIAGIGWWALYRFGEPLVSIAAAIKSGKPMPALSTFIHA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHH
FLQIITIALGSPLGREVAPREVSSVFAYWLSSKAGLTPEESKIMLACGAGAGLAAVYNVP
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEECC
LGGAVFVLEVLLCTSNWTVLLPALSSSAIAVLVSWWGLGNESIYQLPEFSLSAPIILWSI
CCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHH
LASPVLGFFAFWFIQIATIQRSKAMHNWQITLACLINFLIIGLFAIYFPSLLGNGKSPAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MEFDQSVGIGLSIVLFMLRNVFVWSSLRVGAQGGLLTPSLANGALLGAILGGIWNLYLPP
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
APIHAFALIGATAFLAAAQKMPLTAIILIFEFTRINFIFLIPIMLAVSGSIGMCQLTKNY
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCE
YIKYKV
EEEEEC
>Mature Secondary Structure
MELTTTENQLFKSSKVSLALVTVLVGIGSGFLGMCLAMLLHYLQHIAYGYSPLHIISNET
CCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCH
FLEGVRASSSERRISILFLCGLIAGIGWWALYRFGEPLVSIAAAIKSGKPMPALSTFIHA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHH
FLQIITIALGSPLGREVAPREVSSVFAYWLSSKAGLTPEESKIMLACGAGAGLAAVYNVP
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEECC
LGGAVFVLEVLLCTSNWTVLLPALSSSAIAVLVSWWGLGNESIYQLPEFSLSAPIILWSI
CCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHH
LASPVLGFFAFWFIQIATIQRSKAMHNWQITLACLINFLIIGLFAIYFPSLLGNGKSPAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MEFDQSVGIGLSIVLFMLRNVFVWSSLRVGAQGGLLTPSLANGALLGAILGGIWNLYLPP
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
APIHAFALIGATAFLAAAQKMPLTAIILIFEFTRINFIFLIPIMLAVSGSIGMCQLTKNY
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCE
YIKYKV
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]