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The map label for this gene is udk [H]

Identifier: 54294742

GI number: 54294742

Start: 2033678

End: 2034376

Strand: Direct

Name: udk [H]

Synonym: lpl1819

Alternate gene names: 54294742

Gene position: 2033678-2034376 (Clockwise)

Preceding gene: 54294741

Following gene: 54294743

Centisome position: 60.79

GC content: 38.48

Gene sequence:

>699_bases
ATGATTGAATTCCAACTGAAAAAACTTTACTATTCGTACAAAATTTTTAATGAAAACATCATGACAAAGCAAGCAATTAT
TATTGGGATTTCCGGCCCATCAGCATCTGGAAAAAGTTTATTAGCAAATACTATAGTCAATGAATTAGGATCCGAGCAGG
TTGTCGTTATCTCTGAAGATGCCTACTATAAAGATAATGGGCATCTACCCTTTACAGAGAGAGAAAAAATAAATTACGAT
CATCCTGACTCCTTTGATCATGCTCTACTTTATGAGCATCTTCGTCAGCTACGAGTTGGAAATACAGTACAAATTCCTAT
TTATTCTCATTCAAAACATCTGCGTTTACCTGAAACGAGGGCAGTGGGTCAACATGCCATTATCGTACTAGAAGGAATAC
TGCTTTTCAGTGATAAAGCTCTGCGCGAAATTATGGATATACGTATATTCATGTCGACTCCTCTTGACGTCTGTTTAACG
CGGCGCTTAAAAAGAGATGTAGTAGAAAGGCATCGATCATTCGAATCGGTCATTCATCAATATGAGACTACAGTTCGCCC
TATGTACATGCAGTTTATTGAGCCTTCAAGCCGCTACGCTGATATAATAGTACCTCGCGGTGGTGAAAACAGAATCGCTA
TAGAGATGATTCAAGCTAAAATGCGGGAATTATTAGCTTCACATACTCGAGGCAGTTGA

Upstream 100 bases:

>100_bases
GCACCAACATTATCTTCCTTATTATTGATTAAACCTCCTGCCGCAGCAGTGGGACAGCCTTTAGTTGAAGTAGTCAATGC
TTTTCATAAGACTGGAGAGA

Downstream 100 bases:

>100_bases
TGTTTTATTAGGCTGTTTAAAAGCAACCTAATTGATATTGTGGTTTTAGTCCAGGATCGAAGTAACACTCACTTCGCCCT
GCTAAATTAAGAATAATGGG

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MIEFQLKKLYYSYKIFNENIMTKQAIIIGISGPSASGKSLLANTIVNELGSEQVVVISEDAYYKDNGHLPFTEREKINYD
HPDSFDHALLYEHLRQLRVGNTVQIPIYSHSKHLRLPETRAVGQHAIIVLEGILLFSDKALREIMDIRIFMSTPLDVCLT
RRLKRDVVERHRSFESVIHQYETTVRPMYMQFIEPSSRYADIIVPRGGENRIAIEMIQAKMRELLASHTRGS

Sequences:

>Translated_232_residues
MIEFQLKKLYYSYKIFNENIMTKQAIIIGISGPSASGKSLLANTIVNELGSEQVVVISEDAYYKDNGHLPFTEREKINYD
HPDSFDHALLYEHLRQLRVGNTVQIPIYSHSKHLRLPETRAVGQHAIIVLEGILLFSDKALREIMDIRIFMSTPLDVCLT
RRLKRDVVERHRSFESVIHQYETTVRPMYMQFIEPSSRYADIIVPRGGENRIAIEMIQAKMRELLASHTRGS
>Mature_232_residues
MIEFQLKKLYYSYKIFNENIMTKQAIIIGISGPSASGKSLLANTIVNELGSEQVVVISEDAYYKDNGHLPFTEREKINYD
HPDSFDHALLYEHLRQLRVGNTVQIPIYSHSKHLRLPETRAVGQHAIIVLEGILLFSDKALREIMDIRIFMSTPLDVCLT
RRLKRDVVERHRSFESVIHQYETTVRPMYMQFIEPSSRYADIIVPRGGENRIAIEMIQAKMRELLASHTRGS

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=210, Percent_Identity=40.4761904761905, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI57863312, Length=210, Percent_Identity=40.4761904761905, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI18699734, Length=211, Percent_Identity=36.4928909952607, Blast_Score=157, Evalue=9e-39,
Organism=Homo sapiens, GI13899253, Length=215, Percent_Identity=37.2093023255814, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI209863022, Length=184, Percent_Identity=33.695652173913, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI87082034, Length=206, Percent_Identity=55.3398058252427, Blast_Score=243, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI17539894, Length=206, Percent_Identity=39.3203883495146, Blast_Score=164, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17539892, Length=206, Percent_Identity=39.3203883495146, Blast_Score=164, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71981181, Length=211, Percent_Identity=30.8056872037915, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6324339, Length=183, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=7e-28,
Organism=Drosophila melanogaster, GI45550449, Length=222, Percent_Identity=36.4864864864865, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28573516, Length=222, Percent_Identity=36.4864864864865, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28573514, Length=222, Percent_Identity=36.4864864864865, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28573512, Length=222, Percent_Identity=36.4864864864865, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI221458995, Length=225, Percent_Identity=34.2222222222222, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24649624, Length=222, Percent_Identity=34.6846846846847, Blast_Score=147, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 26803; Mature: 26803

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEFQLKKLYYSYKIFNENIMTKQAIIIGISGPSASGKSLLANTIVNELGSEQVVVISED
CCEEHHHHHHHHHHEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECC
AYYKDNGHLPFTEREKINYDHPDSFDHALLYEHLRQLRVGNTVQIPIYSHSKHLRLPETR
CEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHH
AVGQHAIIVLEGILLFSDKALREIMDIRIFMSTPLDVCLTRRLKRDVVERHRSFESVIHQ
HCCCHHHHHHHHHHHHCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YETTVRPMYMQFIEPSSRYADIIVPRGGENRIAIEMIQAKMRELLASHTRGS
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIEFQLKKLYYSYKIFNENIMTKQAIIIGISGPSASGKSLLANTIVNELGSEQVVVISED
CCEEHHHHHHHHHHEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECC
AYYKDNGHLPFTEREKINYDHPDSFDHALLYEHLRQLRVGNTVQIPIYSHSKHLRLPETR
CEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHH
AVGQHAIIVLEGILLFSDKALREIMDIRIFMSTPLDVCLTRRLKRDVVERHRSFESVIHQ
HCCCHHHHHHHHHHHHCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YETTVRPMYMQFIEPSSRYADIIVPRGGENRIAIEMIQAKMRELLASHTRGS
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA