Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 54294654

GI number: 54294654

Start: 1934674

End: 1935624

Strand: Direct

Name: trxB [H]

Synonym: lpl1731

Alternate gene names: 54294654

Gene position: 1934674-1935624 (Clockwise)

Preceding gene: 54294637

Following gene: 54294655

Centisome position: 57.83

GC content: 44.37

Gene sequence:

>951_bases
ATGAGCATAAGCAATCACCATCGCTTAATCATACTCGGTTCAGGTCCTGCAGGTTACACTGCTGCAGTCTATGCCGCAAG
AGCCAATCTGAATCCCGTTTTGATCACCGGAATGCAGCCTGGTGGACAATTAACGACCACGACTGATGTAGACAACTGGC
CCGGAGATATTGAAGGATTACAAGGCCCCGCCCTAATGGAGCGTATGCAAAAACACGCGGAACGCTTTGATACTCAAGTC
ATATTCGATCATATTGTCAAAGCTGATTTAGCGCAAGCTCCCTTTACACTACAGGGAGATAGTACTACTTACACCTGCGA
TGCCTTGATTATTGCAACCGGAGCCTCTGCTCGTTATTTGGGATTACCCTCAGAAACTGCCTACCAGGGGCGAGGTGTCT
CAGCATGTGCTACTTGCGATGGATTTTTTTATCGCAATAAAAGTGTTTGTGTTATTGGAGGAGGCAATACTGCCGTTGAA
GAAGCACTTTATTTATCAAATTTGGCGTCTTCCGTTACTCTGATTCACAGACGAGACAGCTTGCGTGCAGAAAAGATATT
GCAGGATAAACTTTTTGAGAAAGCGCATTCCGGTAACATCAAAATAATATGGAACTCAACCCTTGACGAAGTACTGGGCG
ATGAGAAAAAAGTTACAGGAGCCATGATTCGTAACCTTAAAACTGGTGAAACTGATCAACTGGCAATTGACGGTATTTTT
ATAGCCATTGGACACACACCAAATACTGCAATATTTCAAGATCAGCTGGCTATGAGAGACGGTTATATCTTGATTAAGTC
AGGACTTGATGGAATGGCAACAAGCACCTCTGTTCCTGGAGTATTTGCTTGTGGCGACGTTGCAGATCATGTTTATCGTC
AAGCCATTACATCAGCAGGATTTGGGTGCATGGCAGCCCTGGATGCTGAAAAGTACCTGGATTCAATATAA

Upstream 100 bases:

>100_bases
CCTGTTTTCCCGAATGTTGTTTTGCCATAGGTATTTTAATGTTTTTATTTTTGTCATAATATTTGCCATCTTAACACAAA
AAATAAGGAAGGCAGAGACA

Downstream 100 bases:

>100_bases
AATTGGCTTACGATAGCAACTATACTTTTCCTGACCCGGAAACCAGTGATAAACAGGGTTTATTGGCAATTGGGGGTGTT
TTGACCCCCAAGCGAGTGTT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSISNHHRLIILGSGPAGYTAAVYAARANLNPVLITGMQPGGQLTTTTDVDNWPGDIEGLQGPALMERMQKHAERFDTQV
IFDHIVKADLAQAPFTLQGDSTTYTCDALIIATGASARYLGLPSETAYQGRGVSACATCDGFFYRNKSVCVIGGGNTAVE
EALYLSNLASSVTLIHRRDSLRAEKILQDKLFEKAHSGNIKIIWNSTLDEVLGDEKKVTGAMIRNLKTGETDQLAIDGIF
IAIGHTPNTAIFQDQLAMRDGYILIKSGLDGMATSTSVPGVFACGDVADHVYRQAITSAGFGCMAALDAEKYLDSI

Sequences:

>Translated_316_residues
MSISNHHRLIILGSGPAGYTAAVYAARANLNPVLITGMQPGGQLTTTTDVDNWPGDIEGLQGPALMERMQKHAERFDTQV
IFDHIVKADLAQAPFTLQGDSTTYTCDALIIATGASARYLGLPSETAYQGRGVSACATCDGFFYRNKSVCVIGGGNTAVE
EALYLSNLASSVTLIHRRDSLRAEKILQDKLFEKAHSGNIKIIWNSTLDEVLGDEKKVTGAMIRNLKTGETDQLAIDGIF
IAIGHTPNTAIFQDQLAMRDGYILIKSGLDGMATSTSVPGVFACGDVADHVYRQAITSAGFGCMAALDAEKYLDSI
>Mature_315_residues
SISNHHRLIILGSGPAGYTAAVYAARANLNPVLITGMQPGGQLTTTTDVDNWPGDIEGLQGPALMERMQKHAERFDTQVI
FDHIVKADLAQAPFTLQGDSTTYTCDALIIATGASARYLGLPSETAYQGRGVSACATCDGFFYRNKSVCVIGGGNTAVEE
ALYLSNLASSVTLIHRRDSLRAEKILQDKLFEKAHSGNIKIIWNSTLDEVLGDEKKVTGAMIRNLKTGETDQLAIDGIFI
AIGHTPNTAIFQDQLAMRDGYILIKSGLDGMATSTSVPGVFACGDVADHVYRQAITSAGFGCMAALDAEKYLDSI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=317, Percent_Identity=67.5078864353312, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI87081763, Length=297, Percent_Identity=32.996632996633, Blast_Score=147, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=47.3684210526316, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=46.583850931677, Blast_Score=275, Evalue=6e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33798; Mature: 33667

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISNHHRLIILGSGPAGYTAAVYAARANLNPVLITGMQPGGQLTTTTDVDNWPGDIEGL
CCCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEECCCCCCEEEECCCCCCCCCCCCC
QGPALMERMQKHAERFDTQVIFDHIVKADLAQAPFTLQGDSTTYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEEECCCEEEE
GLPSETAYQGRGVSACATCDGFFYRNKSVCVIGGGNTAVEEALYLSNLASSVTLIHRRDS
CCCCCCCCCCCCCEEEEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHEEEEECHHH
LRAEKILQDKLFEKAHSGNIKIIWNSTLDEVLGDEKKVTGAMIRNLKTGETDQLAIDGIF
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEEEE
IAIGHTPNTAIFQDQLAMRDGYILIKSGLDGMATSTSVPGVFACGDVADHVYRQAITSAG
EEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCC
FGCMAALDAEKYLDSI
CHHHHHHCHHHHHHCC
>Mature Secondary Structure 
SISNHHRLIILGSGPAGYTAAVYAARANLNPVLITGMQPGGQLTTTTDVDNWPGDIEGL
CCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEECCCCCCEEEECCCCCCCCCCCCC
QGPALMERMQKHAERFDTQVIFDHIVKADLAQAPFTLQGDSTTYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEEECCCEEEE
GLPSETAYQGRGVSACATCDGFFYRNKSVCVIGGGNTAVEEALYLSNLASSVTLIHRRDS
CCCCCCCCCCCCCEEEEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHEEEEECHHH
LRAEKILQDKLFEKAHSGNIKIIWNSTLDEVLGDEKKVTGAMIRNLKTGETDQLAIDGIF
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEEEE
IAIGHTPNTAIFQDQLAMRDGYILIKSGLDGMATSTSVPGVFACGDVADHVYRQAITSAG
EEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCC
FGCMAALDAEKYLDSI
CHHHHHHCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]