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The map label for this gene is qorA [H]

Identifier: 54294620

GI number: 54294620

Start: 1892143

End: 1893144

Strand: Direct

Name: qorA [H]

Synonym: lpl1696

Alternate gene names: 54294620

Gene position: 1892143-1893144 (Clockwise)

Preceding gene: 54294613

Following gene: 54294623

Centisome position: 56.55

GC content: 39.22

Gene sequence:

>1002_bases
ATGCATTCTTACCTTAAAAAGGATCTTATCTTGCATTACATACAGATTAATAATCCAGGGCCTCATAGTGAATTAACCCT
TGTCGAAGGTCCAAATCCTGGTTTTAATGAATCTCAAATTCTTGTGCGTGTCAAAGCCACAGCCTTGAATAGAGCTGATT
TAATGCAAAAATATGGTAAATATCCCCCTCCTCCAGGAGAATCCGATATACCTGGATTAGAAATAGCTGGAGAAGTAATC
GTCACTGGTTCCAAGGTAAAACAATTTAAACCGGGTGATAAAATTTACGGTCTTGTCGGGAGTGGGGGTTATGCTGAAGT
CTGTCCAGTAGACGCTTCTTTAGCTCATCATATTCCTTCTCATTGGAGTTATTCATTGGCCGCAGCCCTCCCGGAAGCAT
TAACGACAGTCTATGCTACATTGTACGATTTAGGTGCCTTAAGTTCTGGTCAAACATTATTGATCCATGGCGCTGGAAGC
GGAATAGCTTCATTAGCCATACAAATGGCTAAATTAACAAACACTAAAGTGATAACGACAGTCGGTGATTCCAGTAAAAT
AGAAAAGGCTCTTGCCCTGGGCGCTGATCAAGTCATTCATTACAAAGAACAAGATTTTGAATTATTAATTGAGGACAATT
CTGTCGATTTGATTATTGACTTTGTCGGCGGGGATTATTTTAACAAACACTTACATTTGCTGAAACCTCAGGGTAAATTA
ATCCAAATCGCTTGCCTTAAGGGAAGCAAAGTAGAATGCAGTCTGGCGTTGCTTATGCAAAAAAGGTTGCACATCATTGG
ATTTGTACTCAGATCGCAAAGCATCAAAGAAAAAGCAAGGCTTTGGAAATTGGCTCATGATCATTGGTTTAATGCATTTG
AAAATGACAAGATAAAACCAGTAATTGACTCGGAATTTGATCTAAATCAAATAGAAACAGCGCTGCAACGCATGCAACAA
GGCTCTCATTTCGGAAAAATAGTCATTCGCGTAAGTAAGTAA

Upstream 100 bases:

>100_bases
TAAAATGATAATTATCATCGCAATAGTTTAAAATAAAATTATATCGATTTTAAATCATTATGCGAGTTGTAAAAGATATA
ATATAGTAAATTATCATACT

Downstream 100 bases:

>100_bases
TGCTATGCCTCATCAATTTCTCATGAGCTCAATATTATACGCACAGACTCTTCCAAAGCTGCCTTGACAATGTCCAGTGA
GTTCGTGTTTTTGGTAGATA

Product: hypothetical protein

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MHSYLKKDLILHYIQINNPGPHSELTLVEGPNPGFNESQILVRVKATALNRADLMQKYGKYPPPPGESDIPGLEIAGEVI
VTGSKVKQFKPGDKIYGLVGSGGYAEVCPVDASLAHHIPSHWSYSLAAALPEALTTVYATLYDLGALSSGQTLLIHGAGS
GIASLAIQMAKLTNTKVITTVGDSSKIEKALALGADQVIHYKEQDFELLIEDNSVDLIIDFVGGDYFNKHLHLLKPQGKL
IQIACLKGSKVECSLALLMQKRLHIIGFVLRSQSIKEKARLWKLAHDHWFNAFENDKIKPVIDSEFDLNQIETALQRMQQ
GSHFGKIVIRVSK

Sequences:

>Translated_333_residues
MHSYLKKDLILHYIQINNPGPHSELTLVEGPNPGFNESQILVRVKATALNRADLMQKYGKYPPPPGESDIPGLEIAGEVI
VTGSKVKQFKPGDKIYGLVGSGGYAEVCPVDASLAHHIPSHWSYSLAAALPEALTTVYATLYDLGALSSGQTLLIHGAGS
GIASLAIQMAKLTNTKVITTVGDSSKIEKALALGADQVIHYKEQDFELLIEDNSVDLIIDFVGGDYFNKHLHLLKPQGKL
IQIACLKGSKVECSLALLMQKRLHIIGFVLRSQSIKEKARLWKLAHDHWFNAFENDKIKPVIDSEFDLNQIETALQRMQQ
GSHFGKIVIRVSK
>Mature_333_residues
MHSYLKKDLILHYIQINNPGPHSELTLVEGPNPGFNESQILVRVKATALNRADLMQKYGKYPPPPGESDIPGLEIAGEVI
VTGSKVKQFKPGDKIYGLVGSGGYAEVCPVDASLAHHIPSHWSYSLAAALPEALTTVYATLYDLGALSSGQTLLIHGAGS
GIASLAIQMAKLTNTKVITTVGDSSKIEKALALGADQVIHYKEQDFELLIEDNSVDLIIDFVGGDYFNKHLHLLKPQGKL
IQIACLKGSKVECSLALLMQKRLHIIGFVLRSQSIKEKARLWKLAHDHWFNAFENDKIKPVIDSEFDLNQIETALQRMQQ
GSHFGKIVIRVSK

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=329, Percent_Identity=31.9148936170213, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI22538444, Length=329, Percent_Identity=31.9148936170213, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI24308257, Length=340, Percent_Identity=29.7058823529412, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI18379349, Length=310, Percent_Identity=28.3870967741935, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI194239674, Length=289, Percent_Identity=26.9896193771626, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI13236495, Length=289, Percent_Identity=26.9896193771626, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI47519420, Length=333, Percent_Identity=27.9279279279279, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI28557745, Length=325, Percent_Identity=28.3076923076923, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI41872631, Length=302, Percent_Identity=24.5033112582781, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI194239676, Length=285, Percent_Identity=25.2631578947368, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI67078404, Length=242, Percent_Identity=26.8595041322314, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790485, Length=252, Percent_Identity=32.9365079365079, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI226510941, Length=316, Percent_Identity=25.9493670886076, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=310, Percent_Identity=24.5161290322581, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI212642053, Length=357, Percent_Identity=26.6106442577031, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536829, Length=237, Percent_Identity=28.2700421940928, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=332, Percent_Identity=22.289156626506, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=345, Percent_Identity=23.1884057971014, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323961, Length=336, Percent_Identity=24.1071428571429, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24581345, Length=331, Percent_Identity=25.0755287009063, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19920632, Length=297, Percent_Identity=24.2424242424242, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221330659, Length=297, Percent_Identity=24.2424242424242, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550423, Length=277, Percent_Identity=25.9927797833935, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 36566; Mature: 36566

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSYLKKDLILHYIQINNPGPHSELTLVEGPNPGFNESQILVRVKATALNRADLMQKYGK
CCHHHHHHHEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEEEEEHHCCHHHHHHHHCC
YPPPPGESDIPGLEIAGEVIVTGSKVKQFKPGDKIYGLVGSGGYAEVCPVDASLAHHIPS
CCCCCCCCCCCCCEECCEEEEECCHHHCCCCCCCEEEEECCCCCCEECCCCHHHHHCCCC
HWSYSLAAALPEALTTVYATLYDLGALSSGQTLLIHGAGSGIASLAIQMAKLTNTKVITT
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEE
VGDSSKIEKALALGADQVIHYKEQDFELLIEDNSVDLIIDFVGGDYFNKHLHLLKPQGKL
ECCCHHHHHHHHCCCHHHEEECCCCEEEEEECCCEEEEEEECCCCHHCCCEEEECCCCCE
IQIACLKGSKVECSLALLMQKRLHIIGFVLRSQSIKEKARLWKLAHDHWFNAFENDKIKP
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
VIDSEFDLNQIETALQRMQQGSHFGKIVIRVSK
EECCCCCHHHHHHHHHHHHCCCCEEEEEEEEEC
>Mature Secondary Structure
MHSYLKKDLILHYIQINNPGPHSELTLVEGPNPGFNESQILVRVKATALNRADLMQKYGK
CCHHHHHHHEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEEEEEHHCCHHHHHHHHCC
YPPPPGESDIPGLEIAGEVIVTGSKVKQFKPGDKIYGLVGSGGYAEVCPVDASLAHHIPS
CCCCCCCCCCCCCEECCEEEEECCHHHCCCCCCCEEEEECCCCCCEECCCCHHHHHCCCC
HWSYSLAAALPEALTTVYATLYDLGALSSGQTLLIHGAGSGIASLAIQMAKLTNTKVITT
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEE
VGDSSKIEKALALGADQVIHYKEQDFELLIEDNSVDLIIDFVGGDYFNKHLHLLKPQGKL
ECCCHHHHHHHHCCCHHHEEECCCCEEEEEECCCEEEEEEECCCCHHCCCEEEECCCCCE
IQIACLKGSKVECSLALLMQKRLHIIGFVLRSQSIKEKARLWKLAHDHWFNAFENDKIKP
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
VIDSEFDLNQIETALQRMQQGSHFGKIVIRVSK
EECCCCCHHHHHHHHHHHHCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]