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The map label for this gene is dsbD [H]

Identifier: 54294570

GI number: 54294570

Start: 1834159

End: 1835508

Strand: Reverse

Name: dsbD [H]

Synonym: lpl1646

Alternate gene names: 54294570

Gene position: 1835508-1834159 (Counterclockwise)

Preceding gene: 54294571

Following gene: 54294569

Centisome position: 54.86

GC content: 37.33

Gene sequence:

>1350_bases
ATGAGAAAATTAATTAATTCGTTCATGATTTTATTTCTGATATTTTTTACTCAGGCGGCGTGGTCATATACTCCTGGCTT
TGAAAGTTCTAACCCGGATACTGTGATGCATTTTATTACAGGAAATAGTGCTTTTGTTTATTTGAGTGCTTTTTTCGGAT
TAGGTATTTTGTTGGCTTTTACGCCCTGTGTTCTACCGATGGTTCCTATTTTATCAGGAATTATTGTAGGACAAAATTCT
ATTTCTACAGGAAAATCCTTTAAATTATCAATGAGTTATGTGACTGGAATGGCTATCACTTATGCAGGGGCAGGGATGCT
TGCGGGGTATATGGGAAGTACAATCCAAACTGTAATGCAACGTCCGGTAGTAATCACTTTATTCAGTGTTGTGTTTGTAG
CCATGGCTCTTTCAATGTTTGGCTTTTTTGAATTGAAACTATCTGTAAGCCTTGGGAATCGGTTAAATAAAAACAATCAA
TTAGGGAAGCAAAGAGGTTATCTTTCTGTTGGGATAATGGGAGTTTTATCCACTTTAATTGTTTCTCCTTGTGTTACTGC
TCCTTTAATTGGTGTTTTAAGTTATATTGGTCAAAATGGCCAGGTCATAATGGGCGGATTGATTTTATTTGTTATGGCAT
TAGGGATGGGGGTTCCTCTGCTGATTGTTGGTGCGGGTTATGGCACCTTACTCCCCAAAGCAGGTTCCTGGATGCTTAAA
ATAAAACAATTGTTTGGTTTTATCATGTTGGGAATTGCCATATGGATGTTATCCCGGATTCTGAATCAGACCATTACGCA
TATTTTGTGGGCAGGATTGCTCATTGTCGCCAGCATCAGTTTAGGTGCTTTAAAATCACAAAACAATTGGCGTGGTTATT
TGGCTCAGGGATTGGGTATTCTTGCTTTGATTTCAGGAGGTATTATTTTTTACAACACCGCAATACCTTCAGTAAAAATA
AAACAAGCGTCTGTAGAAAATAACCCATTTATCAAGATTAATACCTTAAACGCTCTTCAACTGCAATTGGAGCAGGCTAA
AAAAGTTAGAAAAGCAGTATTTCTTGATTTCTCAGCGGATTGGTGCAGTGACTGTCAGGAAATGGATACCAAAGTATTCA
ATCAACCAGAAATTCAAAAAGCCATGTCTGATTGGGTTAGCATTAAAGTGGATATCAGTGATAAGAATGCAGAGGTTGAT
TCTATAAAAAAAGCTTTTGGTATTTATGGAACGCCAACGATGATATTTTTTAATACATCGGGAGAGCCTATTACTCAAAT
GACTTCGGTTGGTTTGATTTCACTATCAAAAATGCTTCAATTGCTTGAGCAAGCGCGCCATTTGAGTTGA

Upstream 100 bases:

>100_bases
CTTCTTGTCAGTCGTGGCTGTGCAAGAGGTCCAGTGTAGGTCACTTGTACTCTGATACAAGTATCTACCGTTGTTATTTA
TTACTTATTGGGACATTAAA

Downstream 100 bases:

>100_bases
AATAATAGACAATTTGCTACCAAAATTTGTTCTTAATAATTTGGGTATGGTTAATATTTGATAAATAAATCAAATTCAAA
CTGTACCCAAACTATTGAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MRKLINSFMILFLIFFTQAAWSYTPGFESSNPDTVMHFITGNSAFVYLSAFFGLGILLAFTPCVLPMVPILSGIIVGQNS
ISTGKSFKLSMSYVTGMAITYAGAGMLAGYMGSTIQTVMQRPVVITLFSVVFVAMALSMFGFFELKLSVSLGNRLNKNNQ
LGKQRGYLSVGIMGVLSTLIVSPCVTAPLIGVLSYIGQNGQVIMGGLILFVMALGMGVPLLIVGAGYGTLLPKAGSWMLK
IKQLFGFIMLGIAIWMLSRILNQTITHILWAGLLIVASISLGALKSQNNWRGYLAQGLGILALISGGIIFYNTAIPSVKI
KQASVENNPFIKINTLNALQLQLEQAKKVRKAVFLDFSADWCSDCQEMDTKVFNQPEIQKAMSDWVSIKVDISDKNAEVD
SIKKAFGIYGTPTMIFFNTSGEPITQMTSVGLISLSKMLQLLEQARHLS

Sequences:

>Translated_449_residues
MRKLINSFMILFLIFFTQAAWSYTPGFESSNPDTVMHFITGNSAFVYLSAFFGLGILLAFTPCVLPMVPILSGIIVGQNS
ISTGKSFKLSMSYVTGMAITYAGAGMLAGYMGSTIQTVMQRPVVITLFSVVFVAMALSMFGFFELKLSVSLGNRLNKNNQ
LGKQRGYLSVGIMGVLSTLIVSPCVTAPLIGVLSYIGQNGQVIMGGLILFVMALGMGVPLLIVGAGYGTLLPKAGSWMLK
IKQLFGFIMLGIAIWMLSRILNQTITHILWAGLLIVASISLGALKSQNNWRGYLAQGLGILALISGGIIFYNTAIPSVKI
KQASVENNPFIKINTLNALQLQLEQAKKVRKAVFLDFSADWCSDCQEMDTKVFNQPEIQKAMSDWVSIKVDISDKNAEVD
SIKKAFGIYGTPTMIFFNTSGEPITQMTSVGLISLSKMLQLLEQARHLS
>Mature_449_residues
MRKLINSFMILFLIFFTQAAWSYTPGFESSNPDTVMHFITGNSAFVYLSAFFGLGILLAFTPCVLPMVPILSGIIVGQNS
ISTGKSFKLSMSYVTGMAITYAGAGMLAGYMGSTIQTVMQRPVVITLFSVVFVAMALSMFGFFELKLSVSLGNRLNKNNQ
LGKQRGYLSVGIMGVLSTLIVSPCVTAPLIGVLSYIGQNGQVIMGGLILFVMALGMGVPLLIVGAGYGTLLPKAGSWMLK
IKQLFGFIMLGIAIWMLSRILNQTITHILWAGLLIVASISLGALKSQNNWRGYLAQGLGILALISGGIIFYNTAIPSVKI
KQASVENNPFIKINTLNALQLQLEQAKKVRKAVFLDFSADWCSDCQEMDTKVFNQPEIQKAMSDWVSIKVDISDKNAEVD
SIKKAFGIYGTPTMIFFNTSGEPITQMTSVGLISLSKMLQLLEQARHLS

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=386, Percent_Identity=35.4922279792746, Blast_Score=238, Evalue=6e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 48770; Mature: 48770

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS01319 RBFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLINSFMILFLIFFTQAAWSYTPGFESSNPDTVMHFITGNSAFVYLSAFFGLGILLAF
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
TPCVLPMVPILSGIIVGQNSISTGKSFKLSMSYVTGMAITYAGAGMLAGYMGSTIQTVMQ
HHHHHHHHHHHHHEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPVVITLFSVVFVAMALSMFGFFELKLSVSLGNRLNKNNQLGKQRGYLSVGIMGVLSTLI
CCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHH
VSPCVTAPLIGVLSYIGQNGQVIMGGLILFVMALGMGVPLLIVGAGYGTLLPKAGSWMLK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCHHHHH
IKQLFGFIMLGIAIWMLSRILNQTITHILWAGLLIVASISLGALKSQNNWRGYLAQGLGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LALISGGIIFYNTAIPSVKIKQASVENNPFIKINTLNALQLQLEQAKKVRKAVFLDFSAD
HHHHHCCEEEEECCCCCEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEECCCH
WCSDCQEMDTKVFNQPEIQKAMSDWVSIKVDISDKNAEVDSIKKAFGIYGTPTMIFFNTS
HHHHHHHHHHHHCCCHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECC
GEPITQMTSVGLISLSKMLQLLEQARHLS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKLINSFMILFLIFFTQAAWSYTPGFESSNPDTVMHFITGNSAFVYLSAFFGLGILLAF
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
TPCVLPMVPILSGIIVGQNSISTGKSFKLSMSYVTGMAITYAGAGMLAGYMGSTIQTVMQ
HHHHHHHHHHHHHEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPVVITLFSVVFVAMALSMFGFFELKLSVSLGNRLNKNNQLGKQRGYLSVGIMGVLSTLI
CCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHH
VSPCVTAPLIGVLSYIGQNGQVIMGGLILFVMALGMGVPLLIVGAGYGTLLPKAGSWMLK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCHHHHH
IKQLFGFIMLGIAIWMLSRILNQTITHILWAGLLIVASISLGALKSQNNWRGYLAQGLGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LALISGGIIFYNTAIPSVKIKQASVENNPFIKINTLNALQLQLEQAKKVRKAVFLDFSAD
HHHHHCCEEEEECCCCCEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEECCCH
WCSDCQEMDTKVFNQPEIQKAMSDWVSIKVDISDKNAEVDSIKKAFGIYGTPTMIFFNTS
HHHHHHHHHHHHCCCHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECC
GEPITQMTSVGLISLSKMLQLLEQARHLS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA