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The map label for this gene is corC [H]

Identifier: 54294526

GI number: 54294526

Start: 1776575

End: 1777453

Strand: Direct

Name: corC [H]

Synonym: lpl1602

Alternate gene names: 54294526

Gene position: 1776575-1777453 (Clockwise)

Preceding gene: 54294525

Following gene: 54294527

Centisome position: 53.1

GC content: 35.84

Gene sequence:

>879_bases
ATGAAGTCGAGGAAAATGAACTTGAATAAATTGGAAGATGGTGGGTCGTGGTTTTCTCGTTTAAAACAGTTCTTACAAGG
AGAGCCACAAAATCAGGAAGAATTGGTCAGTTTATTAAGGGACGCGCAAATACGCTCCCTGATTAATTCAGAGACCCTGG
CAATGATTGAGGGAGCTATCCTTTTCTCAAAAATGCGTGTTCGAGACATAATGCTGCCTAAAAATCAAATGGTTTGCATT
AATAAGGATGATGATTTTAAGCATATTATATCTATTGTAACTCAAACGGGACATTCACGTTTTCCTGTAACGGGTGAAAA
CTCTGATGAAGTGGTTGGCATTTTGCACGCAAAAGATTTGTTAAAATATCAACCAGAAAATATGGAATCATTTGATTTAT
TGGACATCTGCCGCCAGGTAACTTTTGTACCTGAAAGCAGACGTCTTGATAGTCTGCTTAGTGAATTTCGAAGTAATAAA
AATCATATGGCTATTGTTGTTGATGAATATGGAGAGGTGTCAGGTTTCGTTACCATTGAAGATATCATTGAACAAATAAT
CGGTGACATAGAAGATGAATTTGATATCGATGAAGACGCCTATATTAAAGCACATGAAGGACACTGCTATATCATCAAAG
CCCATACTCCAATAGAAGAATTTAATGAACAGCTCAACGCTGATTTTAGTGACGAAACCTATGATACAATTGGTGGCATA
GTATTAAATAAATTCGGCTATTTACCTCAACGAGGTGAAGTAATAATCATAGATGATTTTGAATTTAAAGTTCTTAATGC
CGACTCGAGAAGAATAAAGTTATTAGAATGTCTCGATAAAAGAAGTCCCGAGAAACTAAATTCTACTGTTGAAGGATAA

Upstream 100 bases:

>100_bases
TTGCATTTATTAGGGTATGATCATATAAAAGATGAAGAAGCCTCTATTATGCAAATGCTCGAAGCTAAATTACTAGCTGA
ATTAGGTTATGCTAATCCAT

Downstream 100 bases:

>100_bases
GTAATTCATGAGCAGCTCTATTCTCATTATTGATGATGACACAGAACTAACAGATTTATTAACCCAATATTTGGAACCAG
AAGGCTTTAATGTAGTATGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKSRKMNLNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRVRDIMLPKNQMVCI
NKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILHAKDLLKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEFRSNK
NHMAIVVDEYGEVSGFVTIEDIIEQIIGDIEDEFDIDEDAYIKAHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGI
VLNKFGYLPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG

Sequences:

>Translated_292_residues
MKSRKMNLNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRVRDIMLPKNQMVCI
NKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILHAKDLLKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEFRSNK
NHMAIVVDEYGEVSGFVTIEDIIEQIIGDIEDEFDIDEDAYIKAHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGI
VLNKFGYLPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG
>Mature_292_residues
MKSRKMNLNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRVRDIMLPKNQMVCI
NKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILHAKDLLKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEFRSNK
NHMAIVVDEYGEVSGFVTIEDIIEQIIGDIEDEFDIDEDAYIKAHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGI
VLNKFGYLPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=216, Percent_Identity=26.8518518518519, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI94681046, Length=200, Percent_Identity=33.5, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI40068055, Length=196, Percent_Identity=32.1428571428571, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI40068053, Length=196, Percent_Identity=32.1428571428571, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI40068049, Length=150, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786879, Length=252, Percent_Identity=47.2222222222222, Blast_Score=237, Evalue=9e-64,
Organism=Escherichia coli, GI145693175, Length=245, Percent_Identity=26.1224489795918, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082033, Length=265, Percent_Identity=27.1698113207547, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788119, Length=229, Percent_Identity=26.2008733624454, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790664, Length=222, Percent_Identity=25.6756756756757, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33509; Mature: 33509

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRKMNLNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAI
CCCCCCCCHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LFSKMRVRDIMLPKNQMVCINKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILHAKDL
HHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHH
LKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEFRSNKNHMAIVVDEYGEVSGFVTIE
HHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHH
DIIEQIIGDIEDEFDIDEDAYIKAHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGI
HHHHHHHHCCHHHCCCCCCCEEEEECCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
VLNKFGYLPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG
HHHHHCCCCCCCCEEEEECCEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCC
>Mature Secondary Structure
MKSRKMNLNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAI
CCCCCCCCHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LFSKMRVRDIMLPKNQMVCINKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILHAKDL
HHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHH
LKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEFRSNKNHMAIVVDEYGEVSGFVTIE
HHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHH
DIIEQIIGDIEDEFDIDEDAYIKAHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGI
HHHHHHHHCCHHHCCCCCCCEEEEECCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
VLNKFGYLPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG
HHHHHCCCCCCCCEEEEECCEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]