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The map label for this gene is pabB [H]

Identifier: 54294400

GI number: 54294400

Start: 1638609

End: 1639931

Strand: Direct

Name: pabB [H]

Synonym: lpl1469

Alternate gene names: 54294400

Gene position: 1638609-1639931 (Clockwise)

Preceding gene: 54294394

Following gene: 54294401

Centisome position: 48.98

GC content: 36.89

Gene sequence:

>1323_bases
TTGATTGATAGTACTCTTATTACACTTGACTACCATGATTTTTCATCTGAATCCTATGAAAAATTCAGTCGTTTACCTGG
ATTTGTCCTGCTCCAGAGTACGGATAAATCGATGGGTCGTTATGATATTTTAAGTGCTTATCCATATGAGAGGGTGGTTA
TTAAGAACAATATACATGATAAAAATTTAGTATTAACAAAATTAAAAAATAAACTAAAAATAGAGCAGTCAGAATTTGAT
CTTCCTTTTCAGGGCGGAGCCATAGGCTACGTTTCATACGACTTTGGTGCACTATTACATAATCATGAACTATATCCACA
AAAAGATCTGGCGCATATGCCTGTTTTAAATTTCGGATTTTATGATTGGGCTATCATAGTTGATCACCATTTAAAAAAGG
CCACTTTATTTGCAAGAAACAATCATTCTTCAACCAAAAGCGTTGTAGATGAAATAAAGAGTATATTGAATAATCAACGC
ACAAAATCGATACAATTTTCAGTTCAATCTGAATTTTTGCCATTAATATCAAGAGATAATTACAGAAACTCATTCAATGC
CATTCAACAAGCCCTGAGAGCAGGACGCTCTTATCAGGTTAATTTCACGCAGCCGTTTCAAACAAAATTCACCGGGGATC
CCTGGGATATGTACCAAAGGGTTAACAAAAATAACCCTGTCCCCTACGCTGCTTTTATCAGAACTGAGGAAGCTGACATA
TTGAGCTTTTCTCCCGAGCGATTTTTACTTTATGACAACGGTGAAATGTTAACTTCGCCCATAAAAGGCACTATCCACCG
ATCGAAAGATCCTGTTGTAGATAAAAAATTAAAAGAACAGTTATTGAAATGTCCTAAAAACAAGGCTGAAAATGTCATGA
TTGTCGATTTGCTAAGAAACGATCTAGGGAAACTTGCCAAGGCTGGAAGTGTAAAGGTAATGAATCTTTGCCACATCCAG
AGCTTCAATGCAGTACATCATTTGGTTTCCGACATACGAGCTCTATGCAAAGAAGATATTCATCCAATTGAAGCATTTTT
CTCCTGTTTTCCAGGTGGTTCAATTACCGGGGCGCCTAAATTAGAGACGATGAAAATTATCAGCGAACAGGAAACCTATA
AAAGAGAGGTCTATTGTGGTTGCATAGCCTATTTTTCACAACATGGCCGTTTCGATGCCAATATCGCGATACGTACGGTG
ACAGCCAAAGATAATGTTTTGTATTTGGCAGCAGGAGGGGGAATAGTTATTGACTCCGATTGGGAAGATGAATATCGTGA
ATGTTTCACAAAAATTACTGCAGTTATCAATGGAATCAAATAA

Upstream 100 bases:

>100_bases
GAGATAAAAATATACGTTTTTTATTGATAAGTTAGGTTAAAATGACCAAATGAAAAACACTGCATTTTTTCACAGCACAT
CCTTATCTTGAGGTGATAAT

Downstream 100 bases:

>100_bases
TACCCAACAGTCAATCAAAACACATTCATCAGTTATCGTTTTACATGATCTTTCCAAAGACTCGTTAATTCTTACCAGGC
GAAGTCAGATGCTTAAAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MIDSTLITLDYHDFSSESYEKFSRLPGFVLLQSTDKSMGRYDILSAYPYERVVIKNNIHDKNLVLTKLKNKLKIEQSEFD
LPFQGGAIGYVSYDFGALLHNHELYPQKDLAHMPVLNFGFYDWAIIVDHHLKKATLFARNNHSSTKSVVDEIKSILNNQR
TKSIQFSVQSEFLPLISRDNYRNSFNAIQQALRAGRSYQVNFTQPFQTKFTGDPWDMYQRVNKNNPVPYAAFIRTEEADI
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLKCPKNKAENVMIVDLLRNDLGKLAKAGSVKVMNLCHIQ
SFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPKLETMKIISEQETYKREVYCGCIAYFSQHGRFDANIAIRTV
TAKDNVLYLAAGGGIVIDSDWEDEYRECFTKITAVINGIK

Sequences:

>Translated_440_residues
MIDSTLITLDYHDFSSESYEKFSRLPGFVLLQSTDKSMGRYDILSAYPYERVVIKNNIHDKNLVLTKLKNKLKIEQSEFD
LPFQGGAIGYVSYDFGALLHNHELYPQKDLAHMPVLNFGFYDWAIIVDHHLKKATLFARNNHSSTKSVVDEIKSILNNQR
TKSIQFSVQSEFLPLISRDNYRNSFNAIQQALRAGRSYQVNFTQPFQTKFTGDPWDMYQRVNKNNPVPYAAFIRTEEADI
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLKCPKNKAENVMIVDLLRNDLGKLAKAGSVKVMNLCHIQ
SFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPKLETMKIISEQETYKREVYCGCIAYFSQHGRFDANIAIRTV
TAKDNVLYLAAGGGIVIDSDWEDEYRECFTKITAVINGIK
>Mature_440_residues
MIDSTLITLDYHDFSSESYEKFSRLPGFVLLQSTDKSMGRYDILSAYPYERVVIKNNIHDKNLVLTKLKNKLKIEQSEFD
LPFQGGAIGYVSYDFGALLHNHELYPQKDLAHMPVLNFGFYDWAIIVDHHLKKATLFARNNHSSTKSVVDEIKSILNNQR
TKSIQFSVQSEFLPLISRDNYRNSFNAIQQALRAGRSYQVNFTQPFQTKFTGDPWDMYQRVNKNNPVPYAAFIRTEEADI
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLKCPKNKAENVMIVDLLRNDLGKLAKAGSVKVMNLCHIQ
SFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPKLETMKIISEQETYKREVYCGCIAYFSQHGRFDANIAIRTV
TAKDNVLYLAAGGGIVIDSDWEDEYRECFTKITAVINGIK

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=456, Percent_Identity=38.3771929824561, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1787518, Length=397, Percent_Identity=29.7229219143577, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1786809, Length=222, Percent_Identity=22.5225225225225, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320935, Length=429, Percent_Identity=30.0699300699301, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324361, Length=403, Percent_Identity=27.7915632754342, Blast_Score=127, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 50183; Mature: 50183

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSTLITLDYHDFSSESYEKFSRLPGFVLLQSTDKSMGRYDILSAYPYERVVIKNNIHD
CCCCEEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCCCEEHHCCCCCEEEEEECCCCC
KNLVLTKLKNKLKIEQSEFDLPFQGGAIGYVSYDFGALLHNHELYPQKDLAHMPVLNFGF
CHHHHHHHHHHHEEEHHCCCCCCCCCEEEEEEEHHHHHHHCCCCCCCCCCCCCCEEECCC
YDWAIIVDHHLKKATLFARNNHSSTKSVVDEIKSILNNQRTKSIQFSVQSEFLPLISRDN
EEEEEEEHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCC
YRNSFNAIQQALRAGRSYQVNFTQPFQTKFTGDPWDMYQRVNKNNPVPYAAFIRTEEADI
CCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCE
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLKCPKNKAENVMIVDLLRN
EEECCCEEEEEECCCEEECCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHH
DLGKLAKAGSVKVMNLCHIQSFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPK
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
LETMKIISEQETYKREVYCGCIAYFSQHGRFDANIAIRTVTAKDNVLYLAAGGGIVIDSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEEEEEEECCCEEEEEECCCEEECCC
WEDEYRECFTKITAVINGIK
CCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIDSTLITLDYHDFSSESYEKFSRLPGFVLLQSTDKSMGRYDILSAYPYERVVIKNNIHD
CCCCEEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCCCEEHHCCCCCEEEEEECCCCC
KNLVLTKLKNKLKIEQSEFDLPFQGGAIGYVSYDFGALLHNHELYPQKDLAHMPVLNFGF
CHHHHHHHHHHHEEEHHCCCCCCCCCEEEEEEEHHHHHHHCCCCCCCCCCCCCCEEECCC
YDWAIIVDHHLKKATLFARNNHSSTKSVVDEIKSILNNQRTKSIQFSVQSEFLPLISRDN
EEEEEEEHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCC
YRNSFNAIQQALRAGRSYQVNFTQPFQTKFTGDPWDMYQRVNKNNPVPYAAFIRTEEADI
CCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCE
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLKCPKNKAENVMIVDLLRN
EEECCCEEEEEECCCEEECCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHH
DLGKLAKAGSVKVMNLCHIQSFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPK
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
LETMKIISEQETYKREVYCGCIAYFSQHGRFDANIAIRTVTAKDNVLYLAAGGGIVIDSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEEEEEEECCCEEEEEECCCEEECCC
WEDEYRECFTKITAVINGIK
CCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]