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The map label for this gene is yuxL [H]

Identifier: 54294320

GI number: 54294320

Start: 1546408

End: 1548378

Strand: Direct

Name: yuxL [H]

Synonym: lpl1385

Alternate gene names: 54294320

Gene position: 1546408-1548378 (Clockwise)

Preceding gene: 54294319

Following gene: 54294322

Centisome position: 46.22

GC content: 38.56

Gene sequence:

>1971_bases
ATGAAGGAGGTATGCCTGGGTCTAATTATTTGTCTTGTTGTATTTCATGATGGATGGGCTGGGAAGCGTTTGCCAGAGCT
TGATGATCTTTATCGTATACAAAATATCAGCGAGCCAGATCTGTCACCAGATGGAAAATGGGTTGCCTATACCGTATCCC
AATTAAATGCCAAAGATAACATTTCCACGACTGAGGTATGGAAAGTATCAGTGGATAGTAAATCCAGTCAACAAATTACC
TTTGCAGAAGATTCGTCAAGCTCGCTACCCAAATGGAGTCCTAATGGTAAATGGTTAGCTTACTTATCCGATGGCGGGAA
AGAGGGTACGACACAAATTTGGATAGCATCAGTCCAGGATAATAAAGAACATCAACTAACTTATATTGATGGTGAAGTGA
GCGATTTTACATGGTCCCCAGATTCTAACAGGATTGCATTTATAGCTCAGAAGAGTGATCCATCTAATGAGGAAGAACAA
CCCATAGTTGTAGATAGATATCAATTTAAGGTTGATGGTGTCGGTTATCTTGGTAAGGGAAGAGATCATTTATATTTGGT
TGAACTTAAGAGTAAGGCTATTACTCAACTGACTGATGGAAATCATGATGAATATTTACCGGCCTGGTCACCTGATGGAA
AATACATCGCGTTTGTCACAAAGCGTGGAAAAGATCCGGATAGGCATTTTAATTATGATATTTATTTGATCGAACCCAAG
TCTGGGGCAAAAGAGCGCCAACTCACTCATTTCCCCGGTAGTGATATGAATCCTGATTATGATTCAAATCTTTCCTGGAG
CCCGGATAGTTCAAAAATTGCTTATCTTCGCAGTAATGAACATCAATGGACCTATTATTCGCCCAATCAATTGGCAATTA
TTGATATCAATACTAAAGATGAGAGAATCATTGCACCTCGGGATAATTGGTATTACAAGCCAAAATGGTCTCAAGATGGC
AAATTTATTTATGCATTAATAGAAGAAAGCAGAAACACCTATTTGAATCGCATAGACATTCATTCCGGCCAGGTAAAAAA
ATTGACAGGCGGCTTGCGCTATGACATGGATTATTCACTTGCCAAAGGGAAAATTATTTTGTTAACCACAGATGATACAC
ATCCCTCTGAATTATTTATTTTGAATTCCGGATTAATTCCTTTAACACAACATAATAAAAAGCTACTGGATAGAGTTAAA
TTTCAACCCGCAGAAGACATACAGTGCAATAGCTTTGATGGAACAAGAGTTGATGGATTATTAATGAAGCCAGCTAAATA
CCAGTCGGGTATTTTATTTCCTGGTTTTGTCTATCTGCATGGAGGACCAGTCTATCAATTTAGTCATGAATTTAACTTTG
ATATGCAGTGGATAGCAGCCAATAATTATGTCGTCATTGCTCCTAATCCAAGAGGGAGTTCCGGAAGGGGGTTTCATTAT
GCAAAAGCAATTTTTGCAGATTGGGGTAATTTGGATGTAAAAGACATATTGGCTTCTGTTGATTATGTCATAGGGAAGGG
AATGGTTGATCCGAATCGTTTGGGAATAGGCGGATGGAGTTACGGAGGAATGTTAACCAATTATGTCATAGCTACAGATA
GCCGTTTCAAAGCGGCTATATCAGGTGCTGGAGCAGCGAATATTTTAGCTGGTTATGGTGTCGATCAATATACCCCGGAA
TACGAGCTGGAATTAGGAAAGCCCTGGACCAATCCTGAATTGTATCTAAAATTAAGCTACCCTTTTCTTAAAGCGAATAA
TATAAAAACACCTACATTATTTTTGTGCAGTGGCTTGGATTTTAATGTTCCTTGTGTTGGGTCAGAACAATTATACCAAG
CTTTGAAATCACTCGATGTGCCCACACAGCTGGTTATTTACCCCAATGAATATCATACTTTGGAGAAACCAAGCTTTGTC
ATCGACAGATTAAAAAGATATACCAACTGGCTAGATGCTTATGTTAAATAA

Upstream 100 bases:

>100_bases
TGTTTGCTGATTGCCGGGAAAATCATATATAACAAATTTATTCTATACTTTTTAAGGCACTATAAATCTCTGATTTTTCA
GCATAATAAGGATGATTGTC

Downstream 100 bases:

>100_bases
CAATCCTGCCTAGTCGGTCAAAACAAGATGGTAATGAGTCCAATAATTAAAAAAGCGCATGCAGCTACAGCACGAATTAT
TTTCATGGGAATTTTATGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MKEVCLGLIICLVVFHDGWAGKRLPELDDLYRIQNISEPDLSPDGKWVAYTVSQLNAKDNISTTEVWKVSVDSKSSQQIT
FAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQDNKEHQLTYIDGEVSDFTWSPDSNRIAFIAQKSDPSNEEEQ
PIVVDRYQFKVDGVGYLGKGRDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLIEPK
SGAKERQLTHFPGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKDERIIAPRDNWYYKPKWSQDG
KFIYALIEESRNTYLNRIDIHSGQVKKLTGGLRYDMDYSLAKGKIILLTTDDTHPSELFILNSGLIPLTQHNKKLLDRVK
FQPAEDIQCNSFDGTRVDGLLMKPAKYQSGILFPGFVYLHGGPVYQFSHEFNFDMQWIAANNYVVIAPNPRGSSGRGFHY
AKAIFADWGNLDVKDILASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAISGAGAANILAGYGVDQYTPE
YELELGKPWTNPELYLKLSYPFLKANNIKTPTLFLCSGLDFNVPCVGSEQLYQALKSLDVPTQLVIYPNEYHTLEKPSFV
IDRLKRYTNWLDAYVK

Sequences:

>Translated_656_residues
MKEVCLGLIICLVVFHDGWAGKRLPELDDLYRIQNISEPDLSPDGKWVAYTVSQLNAKDNISTTEVWKVSVDSKSSQQIT
FAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQDNKEHQLTYIDGEVSDFTWSPDSNRIAFIAQKSDPSNEEEQ
PIVVDRYQFKVDGVGYLGKGRDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLIEPK
SGAKERQLTHFPGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKDERIIAPRDNWYYKPKWSQDG
KFIYALIEESRNTYLNRIDIHSGQVKKLTGGLRYDMDYSLAKGKIILLTTDDTHPSELFILNSGLIPLTQHNKKLLDRVK
FQPAEDIQCNSFDGTRVDGLLMKPAKYQSGILFPGFVYLHGGPVYQFSHEFNFDMQWIAANNYVVIAPNPRGSSGRGFHY
AKAIFADWGNLDVKDILASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAISGAGAANILAGYGVDQYTPE
YELELGKPWTNPELYLKLSYPFLKANNIKTPTLFLCSGLDFNVPCVGSEQLYQALKSLDVPTQLVIYPNEYHTLEKPSFV
IDRLKRYTNWLDAYVK
>Mature_656_residues
MKEVCLGLIICLVVFHDGWAGKRLPELDDLYRIQNISEPDLSPDGKWVAYTVSQLNAKDNISTTEVWKVSVDSKSSQQIT
FAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQDNKEHQLTYIDGEVSDFTWSPDSNRIAFIAQKSDPSNEEEQ
PIVVDRYQFKVDGVGYLGKGRDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLIEPK
SGAKERQLTHFPGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKDERIIAPRDNWYYKPKWSQDG
KFIYALIEESRNTYLNRIDIHSGQVKKLTGGLRYDMDYSLAKGKIILLTTDDTHPSELFILNSGLIPLTQHNKKLLDRVK
FQPAEDIQCNSFDGTRVDGLLMKPAKYQSGILFPGFVYLHGGPVYQFSHEFNFDMQWIAANNYVVIAPNPRGSSGRGFHY
AKAIFADWGNLDVKDILASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAISGAGAANILAGYGVDQYTPE
YELELGKPWTNPELYLKLSYPFLKANNIKTPTLFLCSGLDFNVPCVGSEQLYQALKSLDVPTQLVIYPNEYHTLEKPSFV
IDRLKRYTNWLDAYVK

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI37577089, Length=246, Percent_Identity=30.0813008130081, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI18450280, Length=246, Percent_Identity=30.0813008130081, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI23510451, Length=707, Percent_Identity=21.7821782178218, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI194394146, Length=246, Percent_Identity=29.6747967479675, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI16933540, Length=258, Percent_Identity=27.1317829457364, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17552908, Length=275, Percent_Identity=25.4545454545455, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564632, Length=223, Percent_Identity=29.5964125560538, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564634, Length=223, Percent_Identity=29.5964125560538, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25144537, Length=237, Percent_Identity=27.8481012658228, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25144540, Length=237, Percent_Identity=27.8481012658228, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17550672, Length=233, Percent_Identity=27.8969957081545, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508019, Length=224, Percent_Identity=29.4642857142857, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17508017, Length=224, Percent_Identity=29.4642857142857, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25149159, Length=371, Percent_Identity=24.5283018867925, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45550825, Length=231, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45553511, Length=231, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45551969, Length=231, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 74325; Mature: 74325

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVCLGLIICLVVFHDGWAGKRLPELDDLYRIQNISEPDLSPDGKWVAYTVSQLNAKDN
CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCC
ISTTEVWKVSVDSKSSQQITFAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQD
CCEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECC
NKEHQLTYIDGEVSDFTWSPDSNRIAFIAQKSDPSNEEEQPIVVDRYQFKVDGVGYLGKG
CCCEEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEECCEEEECCC
RDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLIEPK
CCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHCCEEEEEECCC
SGAKERQLTHFPGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKD
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEEEEEECCCC
ERIIAPRDNWYYKPKWSQDGKFIYALIEESRNTYLNRIDIHSGQVKKLTGGLRYDMDYSL
CEEECCCCCCEECCCCCCCCCEEEEEEECCCCCEEEEEECCCCCEEEECCCEEECCCCEE
AKGKIILLTTDDTHPSELFILNSGLIPLTQHNKKLLDRVKFQPAEDIQCNSFDGTRVDGL
CCCEEEEEECCCCCCCEEEEEECCCEEECCCCHHHHHHHCCCCCCCCEECCCCCCCCCEE
LMKPAKYQSGILFPGFVYLHGGPVYQFSHEFNFDMQWIAANNYVVIAPNPRGSSGRGFHY
EECCCCCCCCEECCCEEEEECCEEEEEECCCCCEEEEEEECCEEEEECCCCCCCCCCEEE
AKAIFADWGNLDVKDILASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAI
EEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCEEEEEEEEECCCEEEEE
SGAGAANILAGYGVDQYTPEYELELGKPWTNPELYLKLSYPFLKANNIKTPTLFLCSGLD
CCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCEEECCCCCCCEEEEECCCC
FNVPCVGSEQLYQALKSLDVPTQLVIYPNEYHTLEKPSFVIDRLKRYTNWLDAYVK
CCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEVCLGLIICLVVFHDGWAGKRLPELDDLYRIQNISEPDLSPDGKWVAYTVSQLNAKDN
CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCC
ISTTEVWKVSVDSKSSQQITFAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQD
CCEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECC
NKEHQLTYIDGEVSDFTWSPDSNRIAFIAQKSDPSNEEEQPIVVDRYQFKVDGVGYLGKG
CCCEEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEECCEEEECCC
RDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLIEPK
CCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHCCEEEEEECCC
SGAKERQLTHFPGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKD
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEEEEEECCCC
ERIIAPRDNWYYKPKWSQDGKFIYALIEESRNTYLNRIDIHSGQVKKLTGGLRYDMDYSL
CEEECCCCCCEECCCCCCCCCEEEEEEECCCCCEEEEEECCCCCEEEECCCEEECCCCEE
AKGKIILLTTDDTHPSELFILNSGLIPLTQHNKKLLDRVKFQPAEDIQCNSFDGTRVDGL
CCCEEEEEECCCCCCCEEEEEECCCEEECCCCHHHHHHHCCCCCCCCEECCCCCCCCCEE
LMKPAKYQSGILFPGFVYLHGGPVYQFSHEFNFDMQWIAANNYVVIAPNPRGSSGRGFHY
EECCCCCCCCEECCCEEEEECCEEEEEECCCCCEEEEEEECCEEEEECCCCCCCCCCEEE
AKAIFADWGNLDVKDILASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAI
EEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCEEEEEEEEECCCEEEEE
SGAGAANILAGYGVDQYTPEYELELGKPWTNPELYLKLSYPFLKANNIKTPTLFLCSGLD
CCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCEEECCCCCCCEEEEECCCC
FNVPCVGSEQLYQALKSLDVPTQLVIYPNEYHTLEKPSFVIDRLKRYTNWLDAYVK
CCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]