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The map label for this gene is etfA [H]

Identifier: 54293898

GI number: 54293898

Start: 1066363

End: 1067301

Strand: Direct

Name: etfA [H]

Synonym: lpl0954

Alternate gene names: 54293898

Gene position: 1066363-1067301 (Clockwise)

Preceding gene: 54293897

Following gene: 54293899

Centisome position: 31.87

GC content: 39.62

Gene sequence:

>939_bases
ATGAGCACTTTAGTTTTAGTTGAACATAATAATCAGCAGTTACATCCAGCAACCCGCAATACACTGTCTGCTGCTTTAGA
GCTCGGTGATAAAATTACATTACTAGTGGTTGGATATCAATGCCGTTCAGTAGCTGAGGAGGCAGCCAGTCTGGAAGGAG
TTCATGCTGTTTTGCATGTAGATAATCCTTGTTACGAACATCAATTGGCTGAAGCAGTTAGCGATTTGGTGGTGTCTTTT
GCGAATTCATTCAGTGCAATTTTAGCTCCTTCCAGTACTTATGGGAAAAATATATTGCCCAGAGTTGCTGCACAACTTGA
TGTGACTCAGATTTCTGATGTGAGCAAGATAATTAATTCAGACACATTTGAACATCCTGTTTATGCTGGTAATGCCATAG
AGACTGTGCGTGTTTTGGATTCATTAAAAGTAATGACTATTAGAACGACAGCTTTTGATCCCATCACATTAAGCCAGGAA
GTATGTTGCATAGAAAGTATTGATAAGGAATTTCAAGCCAAAGGAAGTCAATTTGTGCGCCATGAATTAAGTAAATCCGA
GAGGCCGGATTTAGGTAGTGCCAAAATAGTTGTTTCTGGCGGTAGAGGGCTACAAAATGCAGAAAAATTTAAATTAATCG
AAGAGTTAGCTGATACTTTGGGCGCAGCAGTAGGGGCATCCAGAGCTGCAGTTGATGCCGGTTTTGTTCCTAATGATTAT
CAGGTAGGTCAAACCGGGAAGGTAGTGGCTCCTATGCTTTATATTGCCGTGGGTATTTCTGGAGCAGTTCAACATTTGGC
AGGTATGAAGGATTCCAAGGTTATTGTTGCAATTAATAAAGACGCAGATGCACCTATTTTTCAAATTGCAACTTATGGGT
TAGTAGGTGATCTGTTTGAATTAGTTCCACAATTAATAGAACAATTAAAGAATCGATAA

Upstream 100 bases:

>100_bases
GCCCCGGCAACGAGAAGTGCTGGTGTCATACTTGATTCTGTGGCTGCATTGTTGGATAAATTACAACATGAAGCCAAAGT
GCTTTAATTAAGGAGATGAG

Downstream 100 bases:

>100_bases
GAGGTAACAATATGTTAGTAGGGGTACCAAAAGAAATCAAATCGCACGAAAACAGAGTAGGACTTGTTCCCTCGAGTGTT
AGAGAAATTATTAGGGCAGG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSTLVLVEHNNQQLHPATRNTLSAALELGDKITLLVVGYQCRSVAEEAASLEGVHAVLHVDNPCYEHQLAEAVSDLVVSF
ANSFSAILAPSSTYGKNILPRVAAQLDVTQISDVSKIINSDTFEHPVYAGNAIETVRVLDSLKVMTIRTTAFDPITLSQE
VCCIESIDKEFQAKGSQFVRHELSKSERPDLGSAKIVVSGGRGLQNAEKFKLIEELADTLGAAVGASRAAVDAGFVPNDY
QVGQTGKVVAPMLYIAVGISGAVQHLAGMKDSKVIVAINKDADAPIFQIATYGLVGDLFELVPQLIEQLKNR

Sequences:

>Translated_312_residues
MSTLVLVEHNNQQLHPATRNTLSAALELGDKITLLVVGYQCRSVAEEAASLEGVHAVLHVDNPCYEHQLAEAVSDLVVSF
ANSFSAILAPSSTYGKNILPRVAAQLDVTQISDVSKIINSDTFEHPVYAGNAIETVRVLDSLKVMTIRTTAFDPITLSQE
VCCIESIDKEFQAKGSQFVRHELSKSERPDLGSAKIVVSGGRGLQNAEKFKLIEELADTLGAAVGASRAAVDAGFVPNDY
QVGQTGKVVAPMLYIAVGISGAVQHLAGMKDSKVIVAINKDADAPIFQIATYGLVGDLFELVPQLIEQLKNR
>Mature_311_residues
STLVLVEHNNQQLHPATRNTLSAALELGDKITLLVVGYQCRSVAEEAASLEGVHAVLHVDNPCYEHQLAEAVSDLVVSFA
NSFSAILAPSSTYGKNILPRVAAQLDVTQISDVSKIINSDTFEHPVYAGNAIETVRVLDSLKVMTIRTTAFDPITLSQEV
CCIESIDKEFQAKGSQFVRHELSKSERPDLGSAKIVVSGGRGLQNAEKFKLIEELADTLGAAVGASRAAVDAGFVPNDYQ
VGQTGKVVAPMLYIAVGISGAVQHLAGMKDSKVIVAINKDADAPIFQIATYGLVGDLFELVPQLIEQLKNR

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=313, Percent_Identity=52.0766773162939, Blast_Score=317, Evalue=9e-87,
Organism=Homo sapiens, GI189181759, Length=273, Percent_Identity=52.7472527472528, Blast_Score=279, Evalue=2e-75,
Organism=Escherichia coli, GI1787990, Length=237, Percent_Identity=34.5991561181435, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786226, Length=229, Percent_Identity=34.9344978165939, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI87082157, Length=120, Percent_Identity=40.8333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=310, Percent_Identity=51.9354838709677, Blast_Score=320, Evalue=4e-88,
Organism=Saccharomyces cerevisiae, GI6325261, Length=291, Percent_Identity=45.360824742268, Blast_Score=230, Evalue=2e-61,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=53.6977491961415, Blast_Score=332, Evalue=3e-91,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=53.6977491961415, Blast_Score=332, Evalue=3e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33426; Mature: 33294

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLVLVEHNNQQLHPATRNTLSAALELGDKITLLVVGYQCRSVAEEAASLEGVHAVLHV
CCEEEEEECCCCEECCHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHEEEEEEE
DNPCYEHQLAEAVSDLVVSFANSFSAILAPSSTYGKNILPRVAAQLDVTQISDVSKIINS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCC
DTFEHPVYAGNAIETVRVLDSLKVMTIRTTAFDPITLSQEVCCIESIDKEFQAKGSQFVR
CCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HELSKSERPDLGSAKIVVSGGRGLQNAEKFKLIEELADTLGAAVGASRAAVDAGFVPNDY
HHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPMLYIAVGISGAVQHLAGMKDSKVIVAINKDADAPIFQIATYGLVGDLFE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
LVPQLIEQLKNR
HHHHHHHHHHCC
>Mature Secondary Structure 
STLVLVEHNNQQLHPATRNTLSAALELGDKITLLVVGYQCRSVAEEAASLEGVHAVLHV
CEEEEEECCCCEECCHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHEEEEEEE
DNPCYEHQLAEAVSDLVVSFANSFSAILAPSSTYGKNILPRVAAQLDVTQISDVSKIINS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCC
DTFEHPVYAGNAIETVRVLDSLKVMTIRTTAFDPITLSQEVCCIESIDKEFQAKGSQFVR
CCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HELSKSERPDLGSAKIVVSGGRGLQNAEKFKLIEELADTLGAAVGASRAAVDAGFVPNDY
HHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPMLYIAVGISGAVQHLAGMKDSKVIVAINKDADAPIFQIATYGLVGDLFE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
LVPQLIEQLKNR
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]