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The map label for this gene is ccmC [H]

Identifier: 54293833

GI number: 54293833

Start: 1002570

End: 1003325

Strand: Direct

Name: ccmC [H]

Synonym: lpl0889

Alternate gene names: 54293833

Gene position: 1002570-1003325 (Clockwise)

Preceding gene: 54293832

Following gene: 54293834

Centisome position: 29.97

GC content: 40.74

Gene sequence:

>756_bases
ATGTGGAAGATATTGTATCAGTTGGCATCGCCAAAAAATTTTTATAACTACGCAGGACGTATCATTCCATGGTTGGCAGT
CAGTGCTTTAGCTACCATAGCCATTGGTATGGTTTGGGGATTGGTATTTGCCCCACCGGATTATCAGCAGGGGGATGCAT
ACCGAATTATTTTTGTTCATGTGCCCAGTGCTTTTTTATCAATGGCATTGTATGCCTGGATGGGGTTTCTGGCCATTTTA
TTGTTGGTGTGGCGTATCAAAATGGCAGGGCTTTTGATTCATAAAGTCGCGCAATTAGGCGCCTGCATGGCATTTCTTGC
TTTAATTACAGGGAGCATTTGGGGTAAACCCATGTGGGGTGCCTGGTGGGTATGGGATGCGCGCCTGACCTCAGAGTTAA
TACTTTTGTTACTCTATCTGGCAATTCTGGCTACCTACCAAGCGGTAAAAAATAAAGAAGATGGAGATAAAATAATAGCA
ATTTTAGCTTTGGTGGGCTTAATTGATTTACCAATAATTCATTATTCAGTTTATTGGTGGAATACTTTACACCAAGGCGC
GACTTTATCTGTGTTTGCCAAACCCAAAATTGCCCTCAGTATGTTGTATCCTTTGTTAATCACTTTGCTGGGTTTTTTCT
TGTATTCCTTGTGGATCATTTTGGAAAAAGCACGTAATGAAGTCTTATTCAGGGAGAGAAAGCAATCATGGGTTAAGATT
CAATTTGAGGAAGAGTCTGATGAATCAGTTTTTTGA

Upstream 100 bases:

>100_bases
CTCAAGCGAGCGAAATGTCAACAGACCCTAAGTTTGGAACTAAATTTTGTGATTGTTTTGATGCGTGGTAGAATCCTTCT
TTTTGATTTTATTGTTTCCT

Downstream 100 bases:

>100_bases
ATGGTTGGCAATGGGCGGTTATTCTCTCTATGTTTGGCCTGCTTATGGTTTGGTTTGCGTGGTTTTGGGCATGAATATTT
TAGGAATAAAGTGGCAAAGA

Product: heme exporter protein CcmC

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmC [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MWKILYQLASPKNFYNYAGRIIPWLAVSALATIAIGMVWGLVFAPPDYQQGDAYRIIFVHVPSAFLSMALYAWMGFLAIL
LLVWRIKMAGLLIHKVAQLGACMAFLALITGSIWGKPMWGAWWVWDARLTSELILLLLYLAILATYQAVKNKEDGDKIIA
ILALVGLIDLPIIHYSVYWWNTLHQGATLSVFAKPKIALSMLYPLLITLLGFFLYSLWIILEKARNEVLFRERKQSWVKI
QFEEESDESVF

Sequences:

>Translated_251_residues
MWKILYQLASPKNFYNYAGRIIPWLAVSALATIAIGMVWGLVFAPPDYQQGDAYRIIFVHVPSAFLSMALYAWMGFLAIL
LLVWRIKMAGLLIHKVAQLGACMAFLALITGSIWGKPMWGAWWVWDARLTSELILLLLYLAILATYQAVKNKEDGDKIIA
ILALVGLIDLPIIHYSVYWWNTLHQGATLSVFAKPKIALSMLYPLLITLLGFFLYSLWIILEKARNEVLFRERKQSWVKI
QFEEESDESVF
>Mature_251_residues
MWKILYQLASPKNFYNYAGRIIPWLAVSALATIAIGMVWGLVFAPPDYQQGDAYRIIFVHVPSAFLSMALYAWMGFLAIL
LLVWRIKMAGLLIHKVAQLGACMAFLALITGSIWGKPMWGAWWVWDARLTSELILLLLYLAILATYQAVKNKEDGDKIIA
ILALVGLIDLPIIHYSVYWWNTLHQGATLSVFAKPKIALSMLYPLLITLLGFFLYSLWIILEKARNEVLFRERKQSWVKI
QFEEESDESVF

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=239, Percent_Identity=48.9539748953975, Blast_Score=241, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 28719; Mature: 28719

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKILYQLASPKNFYNYAGRIIPWLAVSALATIAIGMVWGLVFAPPDYQQGDAYRIIFVH
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEE
VPSAFLSMALYAWMGFLAILLLVWRIKMAGLLIHKVAQLGACMAFLALITGSIWGKPMWG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AWWVWDARLTSELILLLLYLAILATYQAVKNKEDGDKIIAILALVGLIDLPIIHYSVYWW
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NTLHQGATLSVFAKPKIALSMLYPLLITLLGFFLYSLWIILEKARNEVLFRERKQSWVKI
HHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
QFEEESDESVF
EEECCCCCCCC
>Mature Secondary Structure
MWKILYQLASPKNFYNYAGRIIPWLAVSALATIAIGMVWGLVFAPPDYQQGDAYRIIFVH
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEE
VPSAFLSMALYAWMGFLAILLLVWRIKMAGLLIHKVAQLGACMAFLALITGSIWGKPMWG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AWWVWDARLTSELILLLLYLAILATYQAVKNKEDGDKIIAILALVGLIDLPIIHYSVYWW
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NTLHQGATLSVFAKPKIALSMLYPLLITLLGFFLYSLWIILEKARNEVLFRERKQSWVKI
HHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
QFEEESDESVF
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]