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The map label for this gene is lolC [H]

Identifier: 54293825

GI number: 54293825

Start: 994587

End: 995837

Strand: Reverse

Name: lolC [H]

Synonym: lpl0881

Alternate gene names: 54293825

Gene position: 995837-994587 (Counterclockwise)

Preceding gene: 54293826

Following gene: 54293824

Centisome position: 29.76

GC content: 39.01

Gene sequence:

>1251_bases
ATGAAGCTATTTTTAAAGATCGCTTTAAAACATTTGCTTGCACGCAAACGGCAAAGCCTGGTTTCTTTGATGGGAATTGT
ATTGGGGGTAGCCTTCTTTTTAACAATTTCGTCACTGATGCAGGGGGCTGAAAAAGATTTCATCAAACGCTTGGTGGATA
ATTCACCACATATCACAATCATCGATGAATATCGAAACCCTCGTATACAACCCATTCAACAGCTGCACACACATGGCGCT
ATTGAAATTCGCAGTGTTAAACCATTAACAGAACCTCGAGGGATTAGAGGGTATGAACAAACAATAAATAATATATCGCT
TACTATCCCGGGAATTGTTATTTCTCCTGTTCTAATTGGACAAGCCTTAATTAGTTATGCGGGAAAAGATTATTCGGTCA
CTCTGAATGGTATGATTCCTGAAGAGATAAAAAAAGTTTCTACTATCGAAAATTATATGACCTCAGGTTCAATTGATGAT
CTCATAGTCAATCCCGATGGTATTGTCTTGGGAAGCGAGCTCTTGCGTAAATTATCCCTGACAAAAGATGATAACATTAC
TGTGACAGCGCCCAATGGTCAAATACGCACTTTCAAAATTCTTGGCGTATTTCGTACTGGCCGTTCAGATTTTGATACCA
ATCAAGCGTTTATTAGTATTAAACGTGCTCAAGCATTATTAAACCGACCTAACCGCTCCAATAACATCATTATAAAACTA
CCTAACCCCTATCAGGCCTATGACATTGCCTCTCAAATTGAAAAACAGATAGGCTATAAAACTATTTCCTGGCAGGAAAA
ATCGGAAGATTTGCTCAATACACTAGTCATTCGAAATATCATTATGTATAGCGTAGTTAGCGCTGTTTTAATTGTCGCTG
CATTTGGAATTTATAATGTTATTTCGACTGTAGTAATGGAAAAGCACAGAGACATTGCCATACTTAAATCAATCGGTTTC
CAAAAACATGATATTCAATTTATTTTTATCATAGAAGGTTTTCTTCTAGGACTGGTTGGATGTTTGTTAGGACTGCCTTT
GGGAAGTGGACTGATGTACAGTCTCATGCAAGTCCAATTCAAGCCGCCAGGAAGCTCTGAATTGATTAATATGCCACTCG
ATTGGAGTTATTTACAATTTGTCATCGCCACAGCTTTTGCGATGTCCGCTTCAATGATAGCCGCCGTTCTTCCTGCTCAT
AAGGCAGCGCTTGTTCATCCTGTTGATATCCTGCGAGGAGGGGGAATGTGA

Upstream 100 bases:

>100_bases
TAAAAGGTGTCAATATTAACGACCTGGTTGTCTTACAACCTGATAATAAGCTAAAAAATGGGCAAAAAGTGCGTTTCATT
CTTGTAAAACAGGAAGAATA

Downstream 100 bases:

>100_bases
ACAAGATTGTCATAAAAACAAAAGAGCTTTCGCGTCAACTGTCAGGTGAAGTTCCCGTCACTTTAGTCAAGAACATAAAT
CTTGAGGTCAGAGAAGGTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MKLFLKIALKHLLARKRQSLVSLMGIVLGVAFFLTISSLMQGAEKDFIKRLVDNSPHITIIDEYRNPRIQPIQQLHTHGA
IEIRSVKPLTEPRGIRGYEQTINNISLTIPGIVISPVLIGQALISYAGKDYSVTLNGMIPEEIKKVSTIENYMTSGSIDD
LIVNPDGIVLGSELLRKLSLTKDDNITVTAPNGQIRTFKILGVFRTGRSDFDTNQAFISIKRAQALLNRPNRSNNIIIKL
PNPYQAYDIASQIEKQIGYKTISWQEKSEDLLNTLVIRNIIMYSVVSAVLIVAAFGIYNVISTVVMEKHRDIAILKSIGF
QKHDIQFIFIIEGFLLGLVGCLLGLPLGSGLMYSLMQVQFKPPGSSELINMPLDWSYLQFVIATAFAMSASMIAAVLPAH
KAALVHPVDILRGGGM

Sequences:

>Translated_416_residues
MKLFLKIALKHLLARKRQSLVSLMGIVLGVAFFLTISSLMQGAEKDFIKRLVDNSPHITIIDEYRNPRIQPIQQLHTHGA
IEIRSVKPLTEPRGIRGYEQTINNISLTIPGIVISPVLIGQALISYAGKDYSVTLNGMIPEEIKKVSTIENYMTSGSIDD
LIVNPDGIVLGSELLRKLSLTKDDNITVTAPNGQIRTFKILGVFRTGRSDFDTNQAFISIKRAQALLNRPNRSNNIIIKL
PNPYQAYDIASQIEKQIGYKTISWQEKSEDLLNTLVIRNIIMYSVVSAVLIVAAFGIYNVISTVVMEKHRDIAILKSIGF
QKHDIQFIFIIEGFLLGLVGCLLGLPLGSGLMYSLMQVQFKPPGSSELINMPLDWSYLQFVIATAFAMSASMIAAVLPAH
KAALVHPVDILRGGGM
>Mature_416_residues
MKLFLKIALKHLLARKRQSLVSLMGIVLGVAFFLTISSLMQGAEKDFIKRLVDNSPHITIIDEYRNPRIQPIQQLHTHGA
IEIRSVKPLTEPRGIRGYEQTINNISLTIPGIVISPVLIGQALISYAGKDYSVTLNGMIPEEIKKVSTIENYMTSGSIDD
LIVNPDGIVLGSELLRKLSLTKDDNITVTAPNGQIRTFKILGVFRTGRSDFDTNQAFISIKRAQALLNRPNRSNNIIIKL
PNPYQAYDIASQIEKQIGYKTISWQEKSEDLLNTLVIRNIIMYSVVSAVLIVAAFGIYNVISTVVMEKHRDIAILKSIGF
QKHDIQFIFIIEGFLLGLVGCLLGLPLGSGLMYSLMQVQFKPPGSSELINMPLDWSYLQFVIATAFAMSASMIAAVLPAH
KAALVHPVDILRGGGM

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=451, Percent_Identity=21.9512195121951, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787362, Length=344, Percent_Identity=21.8023255813953, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46026; Mature: 46026

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFLKIALKHLLARKRQSLVSLMGIVLGVAFFLTISSLMQGAEKDFIKRLVDNSPHITI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEE
IDEYRNPRIQPIQQLHTHGAIEIRSVKPLTEPRGIRGYEQTINNISLTIPGIVISPVLIG
EECCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHCCEEEEECHHHHHHHHHH
QALISYAGKDYSVTLNGMIPEEIKKVSTIENYMTSGSIDDLIVNPDGIVLGSELLRKLSL
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEHHHHHHHHCC
TKDDNITVTAPNGQIRTFKILGVFRTGRSDFDTNQAFISIKRAQALLNRPNRSNNIIIKL
CCCCCEEEECCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
PNPYQAYDIASQIEKQIGYKTISWQEKSEDLLNTLVIRNIIMYSVVSAVLIVAAFGIYNV
CCCCHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISTVVMEKHRDIAILKSIGFQKHDIQFIFIIEGFLLGLVGCLLGLPLGSGLMYSLMQVQF
HHHHHHHHCCCHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEE
KPPGSSELINMPLDWSYLQFVIATAFAMSASMIAAVLPAHKAALVHPVDILRGGGM
CCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCC
>Mature Secondary Structure
MKLFLKIALKHLLARKRQSLVSLMGIVLGVAFFLTISSLMQGAEKDFIKRLVDNSPHITI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEE
IDEYRNPRIQPIQQLHTHGAIEIRSVKPLTEPRGIRGYEQTINNISLTIPGIVISPVLIG
EECCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHCCEEEEECHHHHHHHHHH
QALISYAGKDYSVTLNGMIPEEIKKVSTIENYMTSGSIDDLIVNPDGIVLGSELLRKLSL
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEHHHHHHHHCC
TKDDNITVTAPNGQIRTFKILGVFRTGRSDFDTNQAFISIKRAQALLNRPNRSNNIIIKL
CCCCCEEEECCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
PNPYQAYDIASQIEKQIGYKTISWQEKSEDLLNTLVIRNIIMYSVVSAVLIVAAFGIYNV
CCCCHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISTVVMEKHRDIAILKSIGFQKHDIQFIFIIEGFLLGLVGCLLGLPLGSGLMYSLMQVQF
HHHHHHHHCCCHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEE
KPPGSSELINMPLDWSYLQFVIATAFAMSASMIAAVLPAHKAALVHPVDILRGGGM
CCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]