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The map label for this gene is murA

Identifier: 54293822

GI number: 54293822

Start: 991707

End: 992975

Strand: Direct

Name: murA

Synonym: lpl0878

Alternate gene names: 54293822

Gene position: 991707-992975 (Clockwise)

Preceding gene: 54293821

Following gene: 54293823

Centisome position: 29.64

GC content: 43.34

Gene sequence:

>1269_bases
ATGGATAAATTATTGATTAATGGTGGTAAAGCATTACATGGTGAAGTGGTCATTTCGGGAGCAAAAAACGCTGCTCTTCC
AATCATGGCTGCCAGTCTATTAGCCAGTGATCACGTCACAATATCTAATGTACCTCATCTTAAAGACATCACTACCATGA
TGGAACTGTTAGGGCAACTGGGAGCTCATTTAATTGTTGATGAAAAGATGAATGTTCAAGTTGACTCCAGTCAAGTCAAT
GAGTTTGTTGCTCCTTACGATCTGGTCAAAACAATGCGTGCCTCCATTTTGGTATTAGGCCCAATGCTGGCGCGCTTCGG
TAAGGCAGATGTTTCTTTGCCCGGTGGATGCGCCATTGGAACAAGGCCAGTTGACCTGCATTTAAAAGCATTAAGAGCCA
TGGGGGCAGACATTACGGTTAAAAATGGCTACATCAATGCTCGTTGCAAAAAGGGACGTCTGCAAGGTAAACGCTTGATG
TTTGACACAGTTACTGTCACAGGAACCGAAAATGTGTTAATGGCTGCTGTGTTGGCAGAAGGCATTACTACGATTAAAAA
TGCTGCGCGCGAACCAGAAGTAGTGGACTTGGCTAACTTTCTGATTCAAATGGGAGCGAAAATTCGAGGCGCAGGTACTT
CAACTATTGAAGTAGAAGGTGTGGAATCACTAAACGGGGGGACTTATTCGGTCATGTCCGATAGAATAGAAGCGGGCACT
TATTTGGCAGCTGGAGCGCTTACTCGTGGTCAAGTGACTGTTAAGAAAGTACGTCCTGATACTTTATTATCTCAATTATG
TAAATTCGAAGAGGCAGGCGCGGAATTAACCATTGGTGAGGATTGGGTCAGTTTAAATATGCATAACAAGCGGCCTCAGG
CAGTTAATATTGCAACCGCCCCTTATCCTGCGTTTGCAACGGATATGCAAGCTCAGTTTATGGCAATGAATTCCGTAGCA
GAAGGTTCTTCAACTATTATAGAAACTATTTTTGAAAACCGATTTATGCATGTTCAAGAGTTACAGAGAATGGGGGCTAA
TATCCAACTTAATGGAAATACAGCCATCGTTCATGGTGTTGAAAAATTAACTGGCGCACCGGTAATGGCTACTGATTTAA
GGGCATCAGCCAGTTTAATTCTCGCGGGCCTGGTTGCTGAAGGGGAAACAGTAGTCGAGCGGATTTATCATGTTGATAGA
GGTTATGAGCGAATAGAAGAAAAGTTATCTCTATTGGGAGCGGACATTAAGAGAGTTTCTGACAGGTGA

Upstream 100 bases:

>100_bases
CAGCAATGGGTTTATGCCCAGCTTAAAGACTTTATTACCACCGGAAGGCTTCATGCTATCAGTATGAAGACATGGACAAA
AGAAGAATGGGGGAAGCAAA

Downstream 100 bases:

>100_bases
TTACAAGAGATGAATTAAGCCTTTTTTTACTGGATTTCTTGAATTGCTCCCAATACCAGGATTATGCACCTAATGGAATT
CAAGTTGAAGGCAAAGACAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MDKLLINGGKALHGEVVISGAKNAALPIMAASLLASDHVTISNVPHLKDITTMMELLGQLGAHLIVDEKMNVQVDSSQVN
EFVAPYDLVKTMRASILVLGPMLARFGKADVSLPGGCAIGTRPVDLHLKALRAMGADITVKNGYINARCKKGRLQGKRLM
FDTVTVTGTENVLMAAVLAEGITTIKNAAREPEVVDLANFLIQMGAKIRGAGTSTIEVEGVESLNGGTYSVMSDRIEAGT
YLAAGALTRGQVTVKKVRPDTLLSQLCKFEEAGAELTIGEDWVSLNMHNKRPQAVNIATAPYPAFATDMQAQFMAMNSVA
EGSSTIIETIFENRFMHVQELQRMGANIQLNGNTAIVHGVEKLTGAPVMATDLRASASLILAGLVAEGETVVERIYHVDR
GYERIEEKLSLLGADIKRVSDR

Sequences:

>Translated_422_residues
MDKLLINGGKALHGEVVISGAKNAALPIMAASLLASDHVTISNVPHLKDITTMMELLGQLGAHLIVDEKMNVQVDSSQVN
EFVAPYDLVKTMRASILVLGPMLARFGKADVSLPGGCAIGTRPVDLHLKALRAMGADITVKNGYINARCKKGRLQGKRLM
FDTVTVTGTENVLMAAVLAEGITTIKNAAREPEVVDLANFLIQMGAKIRGAGTSTIEVEGVESLNGGTYSVMSDRIEAGT
YLAAGALTRGQVTVKKVRPDTLLSQLCKFEEAGAELTIGEDWVSLNMHNKRPQAVNIATAPYPAFATDMQAQFMAMNSVA
EGSSTIIETIFENRFMHVQELQRMGANIQLNGNTAIVHGVEKLTGAPVMATDLRASASLILAGLVAEGETVVERIYHVDR
GYERIEEKLSLLGADIKRVSDR
>Mature_422_residues
MDKLLINGGKALHGEVVISGAKNAALPIMAASLLASDHVTISNVPHLKDITTMMELLGQLGAHLIVDEKMNVQVDSSQVN
EFVAPYDLVKTMRASILVLGPMLARFGKADVSLPGGCAIGTRPVDLHLKALRAMGADITVKNGYINARCKKGRLQGKRLM
FDTVTVTGTENVLMAAVLAEGITTIKNAAREPEVVDLANFLIQMGAKIRGAGTSTIEVEGVESLNGGTYSVMSDRIEAGT
YLAAGALTRGQVTVKKVRPDTLLSQLCKFEEAGAELTIGEDWVSLNMHNKRPQAVNIATAPYPAFATDMQAQFMAMNSVA
EGSSTIIETIFENRFMHVQELQRMGANIQLNGNTAIVHGVEKLTGAPVMATDLRASASLILAGLVAEGETVVERIYHVDR
GYERIEEKLSLLGADIKRVSDR

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=60.8591885441527, Blast_Score=525, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA2_LEGPL (Q5WY61)

Other databases:

- EMBL:   CR628337
- RefSeq:   YP_126237.1
- ProteinModelPortal:   Q5WY61
- SMR:   Q5WY61
- STRING:   Q5WY61
- GeneID:   3114923
- GenomeReviews:   CR628337_GR
- KEGG:   lpf:lpl0878
- NMPDR:   fig|297245.3.peg.1728
- LegioList:   lpl0878
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q5WY61
- ProtClustDB:   PRK09369
- BioCyc:   LPNE297245:LPL0878-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45222; Mature: 45222

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLLINGGKALHGEVVISGAKNAALPIMAASLLASDHVTISNVPHLKDITTMMELLGQL
CCCEEECCCCEEECEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHC
GAHLIVDEKMNVQVDSSQVNEFVAPYDLVKTMRASILVLGPMLARFGKADVSLPGGCAIG
CCEEEEECCCCEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TRPVDLHLKALRAMGADITVKNGYINARCKKGRLQGKRLMFDTVTVTGTENVLMAAVLAE
CCCHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCCCEEEEEEEEEECCHHHHHHHHHHH
GITTIKNAAREPEVVDLANFLIQMGAKIRGAGTSTIEVEGVESLNGGTYSVMSDRIEAGT
HHHHHHHHCCCCCHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCEEHHHHHHHHCCC
YLAAGALTRGQVTVKKVRPDTLLSQLCKFEEAGAELTIGEDWVSLNMHNKRPQAVNIATA
EEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCEEEEECC
PYPAFATDMQAQFMAMNSVAEGSSTIIETIFENRFMHVQELQRMGANIQLNGNTAIVHGV
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCEEEEECH
EKLTGAPVMATDLRASASLILAGLVAEGETVVERIYHVDRGYERIEEKLSLLGADIKRVS
HHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DR
CC
>Mature Secondary Structure
MDKLLINGGKALHGEVVISGAKNAALPIMAASLLASDHVTISNVPHLKDITTMMELLGQL
CCCEEECCCCEEECEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHC
GAHLIVDEKMNVQVDSSQVNEFVAPYDLVKTMRASILVLGPMLARFGKADVSLPGGCAIG
CCEEEEECCCCEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TRPVDLHLKALRAMGADITVKNGYINARCKKGRLQGKRLMFDTVTVTGTENVLMAAVLAE
CCCHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCCCEEEEEEEEEECCHHHHHHHHHHH
GITTIKNAAREPEVVDLANFLIQMGAKIRGAGTSTIEVEGVESLNGGTYSVMSDRIEAGT
HHHHHHHHCCCCCHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCEEHHHHHHHHCCC
YLAAGALTRGQVTVKKVRPDTLLSQLCKFEEAGAELTIGEDWVSLNMHNKRPQAVNIATA
EEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCEEEEECC
PYPAFATDMQAQFMAMNSVAEGSSTIIETIFENRFMHVQELQRMGANIQLNGNTAIVHGV
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCEEEEECH
EKLTGAPVMATDLRASASLILAGLVAEGETVVERIYHVDRGYERIEEKLSLLGADIKRVS
HHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA