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The map label for this gene is csrD [H]

Identifier: 54293804

GI number: 54293804

Start: 976574

End: 978493

Strand: Direct

Name: csrD [H]

Synonym: lpl0860

Alternate gene names: 54293804

Gene position: 976574-978493 (Clockwise)

Preceding gene: 54293803

Following gene: 54293805

Centisome position: 29.19

GC content: 37.14

Gene sequence:

>1920_bases
ATGACATTAACTAAGAAAATGGCTGTAGGCGTGTTGATTATGTTGTTACTCGTTTTTATCGGAACTTATTTCATCACTAT
GAATAATGCGCGTAATTTTTTTATCCAACAACTTGAAAGTAATGCTCAAGATACTGCGACATCATTAGGCTTGTCTTTAT
CTCAGTCTTTAATCAATCATGATGTACCTACCATGGATTCTATGGTTAAAGCTGTTTTTGACAGAGGATATTTCTCATCA
ATTAAGGTACAAGACATAAAAGGGAAAGTGATCATTTTAAAGAGACAATTGCCACAAGAAAGCGATATACCACAATGGTT
TTTGAACTTGATAAAATGGCCATCGACTGAGAAGTCATCCTTAATTATGGATGGGTGGATGCAAGCAGGAGTTGTTTTAG
TCGCTAGTGATCCGAGCTATGTTTACGCCTCTTTGTGGCGTAATGCTGTAGAAATGGTAAACGCTTATCTGATTTTTGCA
TTAGTTGCTTTGGTTCTAAGCTATTGCTTTCTAAAATATTTATTGCAACCTTTAAAACGAGTCACAGCACAGGCTTTGGC
AATTTCAGAACATGAGTTTCCTGTAGAAACGAAGATTCCTAAAACCCCTGAATTGAGGCAAGTTACCTTGGCTATGAACC
AAATGGTTACTAAAGTCAAATCCTTATTTCAAGACCAGTTAAAACAAACAGAATCACTTAGAACACAGGTTTACCAAGAT
TCATTAACAGGGATGAGTAATCGTCGTTATTTTTTACAGCATTTGGCTCTGATCCTGGATAATGAAGATGAATTTATACC
TGGTTATGTCATGATGCTGGTCATAGACGGTCTGGATGAGTTAAATCAGAAGCAAGGGTATCAGCAAGGGGATCAATTGG
TATTAACTGTAGCCAAAATATGTAAAAGCTATTGGAAGCAATCGTCTGTTAGTACATTGGCAAGAATTAACGGGACGACC
TTTGCCTTAATTAGTCATGAAAGGGATCCTTTGGTGTTTGAAAAGGAATGTAAGGAGTTTGAACAAATTTTGAGCCAAGG
TATCACTGATATTAAAATTTGCAAAACATACATGGGGGCTGCGAGTTATTTTCTCCACCAACCTGTCTCCAATCTGTTGT
CAATGGTAGATCAAGCGGTTAAAAAGGCTCGTGAAACTGGCGTATTTTATTGCCAGAAAGAGCATGATACTTATAAATAT
CCCCAGTTAATCAGCGGCGATGAAATTAGAAACTCATTGGAACAGAAAAAAATAAGTTTATATGCACAGGCAGTTACAGA
TGGTAAGAATTGTTTTCATAAAGAGATCTTCGTTCGAATTCGCAACCAGGAAGGGGAAGAGTTAGGAGCTGGTTATTTTA
TACCAGTTGCTGAGAAATTAGGATTGGCCTATCCTATTGATCAGTATGTGCTCAATGAATTAACCCTCATGGACATTGCA
ACACATACCCATTTTGCTCTTAATATTTCAGAAGATACTTTAGCAAATAAAGTCAATAGCACTGGTTATTTGCGGCAATT
GGAAGACACTCCTGCAGCTGTCTTGAGAAATCTCTCACTGGAAATTAATGAGGCTCACGTTTTGTCACATTTTTCAAACT
CCAAGTTCTTTATCAAGCAAGCCAAAAAACTGGGGGTGACAGTTGGAATAGATCGTGTGGGTATTAAATTTTCTCCGTTG
CATTATTTGAGTGATTTAAACATAGATTATTTAAAACTGCATGGGAGTCTGGTGACAGATATTGATGAAAATGAAAGCAA
GCAGTTTTTCATACATTATTTTAATGAAATGGCTAAAACGATGGATATTGCGGTGGTAGCAACTCAAGTGGAAAGCGAGG
CTCAATGGCAAGCATTACAAATAGTCCACATACCTTGGGGGCAGGGACGCTTTTTATCTTCTGTAGAATTAATAAAATAA

Upstream 100 bases:

>100_bases
TTGCGAAAACAAGGGGAGAGAGTTCATTGATGGGGGATTCAAAAAGTTTGGGCAAGTGGGATGCTCTAATGAAACGTATG
GAATAAAAAGGTGATAGACC

Downstream 100 bases:

>100_bases
CGAGATGAAAAACAGATTATTCTCAATGCATTAAAATGAATTCGTGAATAGCCCTAAACCCGCTTGGTGCCTCTGTAAAA
TGGTATAAGAATAAGGTATG

Product: hypothetical protein

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MTLTKKMAVGVLIMLLLVFIGTYFITMNNARNFFIQQLESNAQDTATSLGLSLSQSLINHDVPTMDSMVKAVFDRGYFSS
IKVQDIKGKVIILKRQLPQESDIPQWFLNLIKWPSTEKSSLIMDGWMQAGVVLVASDPSYVYASLWRNAVEMVNAYLIFA
LVALVLSYCFLKYLLQPLKRVTAQALAISEHEFPVETKIPKTPELRQVTLAMNQMVTKVKSLFQDQLKQTESLRTQVYQD
SLTGMSNRRYFLQHLALILDNEDEFIPGYVMMLVIDGLDELNQKQGYQQGDQLVLTVAKICKSYWKQSSVSTLARINGTT
FALISHERDPLVFEKECKEFEQILSQGITDIKICKTYMGAASYFLHQPVSNLLSMVDQAVKKARETGVFYCQKEHDTYKY
PQLISGDEIRNSLEQKKISLYAQAVTDGKNCFHKEIFVRIRNQEGEELGAGYFIPVAEKLGLAYPIDQYVLNELTLMDIA
THTHFALNISEDTLANKVNSTGYLRQLEDTPAAVLRNLSLEINEAHVLSHFSNSKFFIKQAKKLGVTVGIDRVGIKFSPL
HYLSDLNIDYLKLHGSLVTDIDENESKQFFIHYFNEMAKTMDIAVVATQVESEAQWQALQIVHIPWGQGRFLSSVELIK

Sequences:

>Translated_639_residues
MTLTKKMAVGVLIMLLLVFIGTYFITMNNARNFFIQQLESNAQDTATSLGLSLSQSLINHDVPTMDSMVKAVFDRGYFSS
IKVQDIKGKVIILKRQLPQESDIPQWFLNLIKWPSTEKSSLIMDGWMQAGVVLVASDPSYVYASLWRNAVEMVNAYLIFA
LVALVLSYCFLKYLLQPLKRVTAQALAISEHEFPVETKIPKTPELRQVTLAMNQMVTKVKSLFQDQLKQTESLRTQVYQD
SLTGMSNRRYFLQHLALILDNEDEFIPGYVMMLVIDGLDELNQKQGYQQGDQLVLTVAKICKSYWKQSSVSTLARINGTT
FALISHERDPLVFEKECKEFEQILSQGITDIKICKTYMGAASYFLHQPVSNLLSMVDQAVKKARETGVFYCQKEHDTYKY
PQLISGDEIRNSLEQKKISLYAQAVTDGKNCFHKEIFVRIRNQEGEELGAGYFIPVAEKLGLAYPIDQYVLNELTLMDIA
THTHFALNISEDTLANKVNSTGYLRQLEDTPAAVLRNLSLEINEAHVLSHFSNSKFFIKQAKKLGVTVGIDRVGIKFSPL
HYLSDLNIDYLKLHGSLVTDIDENESKQFFIHYFNEMAKTMDIAVVATQVESEAQWQALQIVHIPWGQGRFLSSVELIK
>Mature_638_residues
TLTKKMAVGVLIMLLLVFIGTYFITMNNARNFFIQQLESNAQDTATSLGLSLSQSLINHDVPTMDSMVKAVFDRGYFSSI
KVQDIKGKVIILKRQLPQESDIPQWFLNLIKWPSTEKSSLIMDGWMQAGVVLVASDPSYVYASLWRNAVEMVNAYLIFAL
VALVLSYCFLKYLLQPLKRVTAQALAISEHEFPVETKIPKTPELRQVTLAMNQMVTKVKSLFQDQLKQTESLRTQVYQDS
LTGMSNRRYFLQHLALILDNEDEFIPGYVMMLVIDGLDELNQKQGYQQGDQLVLTVAKICKSYWKQSSVSTLARINGTTF
ALISHERDPLVFEKECKEFEQILSQGITDIKICKTYMGAASYFLHQPVSNLLSMVDQAVKKARETGVFYCQKEHDTYKYP
QLISGDEIRNSLEQKKISLYAQAVTDGKNCFHKEIFVRIRNQEGEELGAGYFIPVAEKLGLAYPIDQYVLNELTLMDIAT
HTHFALNISEDTLANKVNSTGYLRQLEDTPAAVLRNLSLEINEAHVLSHFSNSKFFIKQAKKLGVTVGIDRVGIKFSPLH
YLSDLNIDYLKLHGSLVTDIDENESKQFFIHYFNEMAKTMDIAVVATQVESEAQWQALQIVHIPWGQGRFLSSVELIK

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=446, Percent_Identity=22.6457399103139, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788849, Length=263, Percent_Identity=25.0950570342205, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790496, Length=233, Percent_Identity=26.6094420600858, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081921, Length=432, Percent_Identity=22.6851851851852, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082096, Length=238, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87081845, Length=242, Percent_Identity=24.3801652892562, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787541, Length=406, Percent_Identity=23.3990147783251, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87081743, Length=232, Percent_Identity=25, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1788956, Length=297, Percent_Identity=22.2222222222222, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 72599; Mature: 72468

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50885 HAMP ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTKKMAVGVLIMLLLVFIGTYFITMNNARNFFIQQLESNAQDTATSLGLSLSQSLINH
CCCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
DVPTMDSMVKAVFDRGYFSSIKVQDIKGKVIILKRQLPQESDIPQWFLNLIKWPSTEKSS
CCCCHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCH
LIMDGWMQAGVVLVASDPSYVYASLWRNAVEMVNAYLIFALVALVLSYCFLKYLLQPLKR
HHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTAQALAISEHEFPVETKIPKTPELRQVTLAMNQMVTKVKSLFQDQLKQTESLRTQVYQD
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLTGMSNRRYFLQHLALILDNEDEFIPGYVMMLVIDGLDELNQKQGYQQGDQLVLTVAKI
HHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHH
CKSYWKQSSVSTLARINGTTFALISHERDPLVFEKECKEFEQILSQGITDIKICKTYMGA
HHHHHCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ASYFLHQPVSNLLSMVDQAVKKARETGVFYCQKEHDTYKYPQLISGDEIRNSLEQKKISL
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
YAQAVTDGKNCFHKEIFVRIRNQEGEELGAGYFIPVAEKLGLAYPIDQYVLNELTLMDIA
HHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHCCCCCCHHHHHHHHHHHHHHH
THTHFALNISEDTLANKVNSTGYLRQLEDTPAAVLRNLSLEINEAHVLSHFSNSKFFIKQ
CCCEEEEECCHHHHHHHCCCCHHHHHHCCCHHHHHHHCCCEECHHHHHHHCCCCHHHHHH
AKKLGVTVGIDRVGIKFSPLHYLSDLNIDYLKLHGSLVTDIDENESKQFFIHYFNEMAKT
HHHCCEEEEEECCCCEECCHHHHHCCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHH
MDIAVVATQVESEAQWQALQIVHIPWGQGRFLSSVELIK
HHHHHEEHHHHCCCCEEEEEEEECCCCCCCHHCCHHHCC
>Mature Secondary Structure 
TLTKKMAVGVLIMLLLVFIGTYFITMNNARNFFIQQLESNAQDTATSLGLSLSQSLINH
CCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
DVPTMDSMVKAVFDRGYFSSIKVQDIKGKVIILKRQLPQESDIPQWFLNLIKWPSTEKSS
CCCCHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCH
LIMDGWMQAGVVLVASDPSYVYASLWRNAVEMVNAYLIFALVALVLSYCFLKYLLQPLKR
HHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTAQALAISEHEFPVETKIPKTPELRQVTLAMNQMVTKVKSLFQDQLKQTESLRTQVYQD
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLTGMSNRRYFLQHLALILDNEDEFIPGYVMMLVIDGLDELNQKQGYQQGDQLVLTVAKI
HHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHH
CKSYWKQSSVSTLARINGTTFALISHERDPLVFEKECKEFEQILSQGITDIKICKTYMGA
HHHHHCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ASYFLHQPVSNLLSMVDQAVKKARETGVFYCQKEHDTYKYPQLISGDEIRNSLEQKKISL
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
YAQAVTDGKNCFHKEIFVRIRNQEGEELGAGYFIPVAEKLGLAYPIDQYVLNELTLMDIA
HHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHCCCCCCHHHHHHHHHHHHHHH
THTHFALNISEDTLANKVNSTGYLRQLEDTPAAVLRNLSLEINEAHVLSHFSNSKFFIKQ
CCCEEEEECCHHHHHHHCCCCHHHHHHCCCHHHHHHHCCCEECHHHHHHHCCCCHHHHHH
AKKLGVTVGIDRVGIKFSPLHYLSDLNIDYLKLHGSLVTDIDENESKQFFIHYFNEMAKT
HHHCCEEEEEECCCCEECCHHHHHCCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHH
MDIAVVATQVESEAQWQALQIVHIPWGQGRFLSSVELIK
HHHHHEEHHHHCCCCEEEEEEEECCCCCCCHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]