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The map label for this gene is gltT [H]

Identifier: 54293702

GI number: 54293702

Start: 856177

End: 857424

Strand: Reverse

Name: gltT [H]

Synonym: lpl0755

Alternate gene names: 54293702

Gene position: 857424-856177 (Counterclockwise)

Preceding gene: 54293703

Following gene: 54293701

Centisome position: 25.63

GC content: 38.22

Gene sequence:

>1248_bases
GTGGTAACTCAATTCAATACGCTTAAATCCTATATTTTCCTCATCATTTTGCTATTATCTATTTTACTTGGTGGGTTAAC
AGGATATGTTTTTAATCAAAATGTTGCCTGGTTAAAACCCTTTGGCGATATTTTTCTTAATTTGATTTTTACTACCATCG
TTCCCCTAATTTTTTTCAGTGTATCCTCAGCGATTGCAAGAACTGGTTCTATTGGCAAATTAGGCAAAATATTCTACTCA
ATGACAGTCATATTCTTATTTACAGGAATAGTTGCTGCAGTTTATGCCCTTTTCGTAGTTTTACTTTTCCCTCCAGCGCA
AAACATGCCTGTTCTCTTGGAAAGTTCAAAGCAACTCTCTCCGACAAATCTCCCGGATCGCTTGATAGAGATTTTTACTG
TACCTGAGTTTTCAAAATTATTCTCTCATGAGCATATTCTGGCATTAGTCCTTTTTTCAATCCTGGTAGGATTGGCTGTA
GCCCATTCCAAAGATAAAGGTACAATTTTTAATTCCTTCTTAAAAGCAGGAGAAGACGTATTCATGTCAGTATTTCGCCT
GATTATGTATTATGCTCCTATCGGTTTTTTTGCCTATTTTGCAGTAATAGTAAGCGAAATTGGCCCCCAATTAATGGAAA
ATTATTTACGCATTGCCATACTCTACTATACCGCTTCAGTGTTCTACTTTTTCTTCGCGTTAACTGCCTATGCTTATTTG
GCGGGAAAATCCCACGGTGTCAGGCTATTCTGGAGAAATATTTTCCTTCCTGCAGCAACTTCGATAGCAACTTGTAGTAG
TGCCGCCAGTATTCCTGCCAATTTAATGGCAACCAAATCCATGCGCATCCCTGCTGAAATCTATGAAACATCAATACCCT
TAGGCTCCATAATTCATAAAGATGGATCAGTCATGGGCGGTGTTTTTAAAATTGCCTTTTTATTCGGGATCTTTCATTTA
CCTTTTTCCAGCTTGCCCGTTCTTATAATGGCATTGGGGGTTTCTTTGTTGGTAGGAACAGTGATGGGAGCGATTCCTAG
TGGCGGAATGTTAGGAGAATTGTTAATTTTGTCAGTGTATGGTTTTCCACCTTCTGTTTTAATTGCAGTTGCTGCCATTA
GCATCATCATTGATCCTATAGCGACAATGGTCAACGTAACAAGCAATAGTGTTTGCAGCATGATGATTGCACGTCTGGTC
GAAGGTAAAAATTGGTTTCTCAGTTCCTACAATGAAAATAACCTATAA

Upstream 100 bases:

>100_bases
CCTCCTTACAGTCATGGCTCAACTTAACTCATTATTCTATACGTGGCTGTAAGGAACAAATGGCACAAACCGGATTATTT
AAAAGAAAGGATGTCTTCTC

Downstream 100 bases:

>100_bases
TCTAAGGTATGTTCAATATAAAAAGCACATATTAAATTTTCATTATCCCATATGTGCAATATAAAAGCATTTCTTGGAGG
GAATAGTAATGAAAAAAATA

Product: hypothetical protein

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MVTQFNTLKSYIFLIILLLSILLGGLTGYVFNQNVAWLKPFGDIFLNLIFTTIVPLIFFSVSSAIARTGSIGKLGKIFYS
MTVIFLFTGIVAAVYALFVVLLFPPAQNMPVLLESSKQLSPTNLPDRLIEIFTVPEFSKLFSHEHILALVLFSILVGLAV
AHSKDKGTIFNSFLKAGEDVFMSVFRLIMYYAPIGFFAYFAVIVSEIGPQLMENYLRIAILYYTASVFYFFFALTAYAYL
AGKSHGVRLFWRNIFLPAATSIATCSSAASIPANLMATKSMRIPAEIYETSIPLGSIIHKDGSVMGGVFKIAFLFGIFHL
PFSSLPVLIMALGVSLLVGTVMGAIPSGGMLGELLILSVYGFPPSVLIAVAAISIIIDPIATMVNVTSNSVCSMMIARLV
EGKNWFLSSYNENNL

Sequences:

>Translated_415_residues
MVTQFNTLKSYIFLIILLLSILLGGLTGYVFNQNVAWLKPFGDIFLNLIFTTIVPLIFFSVSSAIARTGSIGKLGKIFYS
MTVIFLFTGIVAAVYALFVVLLFPPAQNMPVLLESSKQLSPTNLPDRLIEIFTVPEFSKLFSHEHILALVLFSILVGLAV
AHSKDKGTIFNSFLKAGEDVFMSVFRLIMYYAPIGFFAYFAVIVSEIGPQLMENYLRIAILYYTASVFYFFFALTAYAYL
AGKSHGVRLFWRNIFLPAATSIATCSSAASIPANLMATKSMRIPAEIYETSIPLGSIIHKDGSVMGGVFKIAFLFGIFHL
PFSSLPVLIMALGVSLLVGTVMGAIPSGGMLGELLILSVYGFPPSVLIAVAAISIIIDPIATMVNVTSNSVCSMMIARLV
EGKNWFLSSYNENNL
>Mature_415_residues
MVTQFNTLKSYIFLIILLLSILLGGLTGYVFNQNVAWLKPFGDIFLNLIFTTIVPLIFFSVSSAIARTGSIGKLGKIFYS
MTVIFLFTGIVAAVYALFVVLLFPPAQNMPVLLESSKQLSPTNLPDRLIEIFTVPEFSKLFSHEHILALVLFSILVGLAV
AHSKDKGTIFNSFLKAGEDVFMSVFRLIMYYAPIGFFAYFAVIVSEIGPQLMENYLRIAILYYTASVFYFFFALTAYAYL
AGKSHGVRLFWRNIFLPAATSIATCSSAASIPANLMATKSMRIPAEIYETSIPLGSIIHKDGSVMGGVFKIAFLFGIFHL
PFSSLPVLIMALGVSLLVGTVMGAIPSGGMLGELLILSVYGFPPSVLIAVAAISIIIDPIATMVNVTSNSVCSMMIARLV
EGKNWFLSSYNENNL

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1790514, Length=423, Percent_Identity=23.8770685579196, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789947, Length=295, Percent_Identity=24.0677966101695, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788024, Length=306, Percent_Identity=23.5294117647059, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71996953, Length=457, Percent_Identity=22.1006564551422, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71983099, Length=451, Percent_Identity=20.8425720620843, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71983106, Length=451, Percent_Identity=20.8425720620843, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17537407, Length=403, Percent_Identity=20.8436724565757, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583025, Length=442, Percent_Identity=21.4932126696833, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17137668, Length=442, Percent_Identity=21.4932126696833, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24583023, Length=442, Percent_Identity=21.4932126696833, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 45358; Mature: 45358

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCC
>Mature Secondary Structure
MVTQFNTLKSYIFLIILLLSILLGGLTGYVFNQNVAWLKPFGDIFLNLIFTTIVPLIFFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VSSAIARTGSIGKLGKIFYSMTVIFLFTGIVAAVYALFVVLLFPPAQNMPVLLESSKQLS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCC
PTNLPDRLIEIFTVPEFSKLFSHEHILALVLFSILVGLAVAHSKDKGTIFNSFLKAGEDV
CCCCHHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHH
FMSVFRLIMYYAPIGFFAYFAVIVSEIGPQLMENYLRIAILYYTASVFYFFFALTAYAYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGKSHGVRLFWRNIFLPAATSIATCSSAASIPANLMATKSMRIPAEIYETSIPLGSIIHK
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHCCCHHHHHHC
DGSVMGGVFKIAFLFGIFHLPFSSLPVLIMALGVSLLVGTVMGAIPSGGMLGELLILSVY
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
GFPPSVLIAVAAISIIIDPIATMVNVTSNSVCSMMIARLVEGKNWFLSSYNENNL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1359385 [H]