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The map label for this gene is tolC [H]

Identifier: 54293683

GI number: 54293683

Start: 836409

End: 837776

Strand: Reverse

Name: tolC [H]

Synonym: lpl0736

Alternate gene names: 54293683

Gene position: 837776-836409 (Counterclockwise)

Preceding gene: 54293684

Following gene: 54293682

Centisome position: 25.04

GC content: 42.32

Gene sequence:

>1368_bases
ATGAGAAAATCTCTGTTTTGTTGGATTTTAACTTTAGGTGTTTCAACCCATGTGTTTGCAACAGACCTAATGGATATCTA
TCAACAAGCTCTGGAGAACGATACCATTTTTAAAGAGGCATATGATAACTATATGTCCAGCACCGAAGCCATTCCCCAAG
CTCGTGCGGCTCTTTACCCTCAAGTCGGCCTTGGTTCACAAGCTGGCCGCAATTATCAGGATGCTGTTGCCGGAGCGTTC
AGTGCCAATCAATACTATGGAAATTATTCATGGCAAGTCAATGCTTCCCAGGCGCTGTTTAACTATCAGGCATGGGCCAA
AGTCGCCCAGGCCAAAGCGTCTGTTAAAGCAGCACAAGCCAGTTTCAATGATGCAGCACAGAATTTAATTCTAAGAACAG
CCAAAGCCTATTTTGATGTCCTGTTTGCCAAAGACACATTAGACTTTGCCGAAGCAAAAAAACGGGCGAACAAAAGACAA
TATGATCAAGCAACTCAACGTTTTCAAGTTGGCCTGGATGCCATCACTTCTGTCTATGAAGCCAAGGCGGCGTACGATCA
ATCCATAGCGACAGTTATCGCTGCCCGCAATAATCAGATTAACCAGAGTGAAAATTTACGAAAACTTACTAATCACGTAT
ACGAAACACTCGCGCCACTCAAAGACAGCAAAATTCCTCTTGTTAAGCCAGAACCAAATGACGTGAATCAATGGATAGAT
ACCGGACTTAAACAAAACTATAAATTATATGCTGCAAAATATAATCTTGAGGTGGCAAAAGACAATGTAAAAGCAATCTC
TGCGGGCAACTGGCCAGTTTTTTCACTACAGAGCAACGCCAGCCAGGTACATAATAATGCATCTGGTAATACTGTTTTTA
TTCCATCAAAGCAAACCCAGGCTAATATTGCAATCGCGATGAATTTTCCTGTTTTTCAAGGAGGCCTGGTCCAGGCTCAG
ACTCGTCAAGCTCAATATAATTTTCAGTCAACGAGTGAAAAACTGGAACAAACGTATCGCGATGTCGTTGTAAACAGCCG
CATTGCTTTCAATACCATCACTGATGGGATAAGCAAGGTAAAGGCGGACAGACAAACGGTCATCTCTGTGCAAAATTCTT
TGCAAAGTACCGAGGCTCAATTTGAAGTAGGCACTCGAACCATGGTAGATGTGGTCAATGCTCAGCAAAGATTGTTTGAA
GCACAGGAACAATTAGCCCGGGATCAATACGATTTGATTAACTCCATACTTACCCTGAAGTACCTTGCAGGGACTTTAAA
CGTTAATGATCTCGAACAGATTAACTCATGGTTAGCAACTACACGTGTCAATGGATTTTCACCCGTAGATAACAAAACCT
CCAAATAA

Upstream 100 bases:

>100_bases
ATAATGCAATCTGGACAGAATCCATGCTTTTTGAAACGGATATACCTCCTCTGGTAGATCAATTGAAACCGAAAGAATTT
GTTTTCTAGGGAAAACTCGA

Downstream 100 bases:

>100_bases
CAAATTTAGGTTTTTTATGTCTTCCAATCCTTCTTCAGTTGAAAAAAAATTACTTCATTATACAGGTAAAGCCATAGCTG
ATTTTAATATGATCCAGCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MRKSLFCWILTLGVSTHVFATDLMDIYQQALENDTIFKEAYDNYMSSTEAIPQARAALYPQVGLGSQAGRNYQDAVAGAF
SANQYYGNYSWQVNASQALFNYQAWAKVAQAKASVKAAQASFNDAAQNLILRTAKAYFDVLFAKDTLDFAEAKKRANKRQ
YDQATQRFQVGLDAITSVYEAKAAYDQSIATVIAARNNQINQSENLRKLTNHVYETLAPLKDSKIPLVKPEPNDVNQWID
TGLKQNYKLYAAKYNLEVAKDNVKAISAGNWPVFSLQSNASQVHNNASGNTVFIPSKQTQANIAIAMNFPVFQGGLVQAQ
TRQAQYNFQSTSEKLEQTYRDVVVNSRIAFNTITDGISKVKADRQTVISVQNSLQSTEAQFEVGTRTMVDVVNAQQRLFE
AQEQLARDQYDLINSILTLKYLAGTLNVNDLEQINSWLATTRVNGFSPVDNKTSK

Sequences:

>Translated_455_residues
MRKSLFCWILTLGVSTHVFATDLMDIYQQALENDTIFKEAYDNYMSSTEAIPQARAALYPQVGLGSQAGRNYQDAVAGAF
SANQYYGNYSWQVNASQALFNYQAWAKVAQAKASVKAAQASFNDAAQNLILRTAKAYFDVLFAKDTLDFAEAKKRANKRQ
YDQATQRFQVGLDAITSVYEAKAAYDQSIATVIAARNNQINQSENLRKLTNHVYETLAPLKDSKIPLVKPEPNDVNQWID
TGLKQNYKLYAAKYNLEVAKDNVKAISAGNWPVFSLQSNASQVHNNASGNTVFIPSKQTQANIAIAMNFPVFQGGLVQAQ
TRQAQYNFQSTSEKLEQTYRDVVVNSRIAFNTITDGISKVKADRQTVISVQNSLQSTEAQFEVGTRTMVDVVNAQQRLFE
AQEQLARDQYDLINSILTLKYLAGTLNVNDLEQINSWLATTRVNGFSPVDNKTSK
>Mature_455_residues
MRKSLFCWILTLGVSTHVFATDLMDIYQQALENDTIFKEAYDNYMSSTEAIPQARAALYPQVGLGSQAGRNYQDAVAGAF
SANQYYGNYSWQVNASQALFNYQAWAKVAQAKASVKAAQASFNDAAQNLILRTAKAYFDVLFAKDTLDFAEAKKRANKRQ
YDQATQRFQVGLDAITSVYEAKAAYDQSIATVIAARNNQINQSENLRKLTNHVYETLAPLKDSKIPLVKPEPNDVNQWID
TGLKQNYKLYAAKYNLEVAKDNVKAISAGNWPVFSLQSNASQVHNNASGNTVFIPSKQTQANIAIAMNFPVFQGGLVQAQ
TRQAQYNFQSTSEKLEQTYRDVVVNSRIAFNTITDGISKVKADRQTVISVQNSLQSTEAQFEVGTRTMVDVVNAQQRLFE
AQEQLARDQYDLINSILTLKYLAGTLNVNDLEQINSWLATTRVNGFSPVDNKTSK

Specific function: Required for proper expression of outer membrane protein genes such as ompF, nmpC, protein 2, hemolysin, colicin V, or colicin E1. May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=428, Percent_Identity=36.6822429906542, Blast_Score=241, Evalue=7e-65,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50735; Mature: 50735

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8801424 [H]