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The map label for this gene is ssb [H]

Identifier: 54293348

GI number: 54293348

Start: 445384

End: 445863

Strand: Reverse

Name: ssb [H]

Synonym: lpl0397

Alternate gene names: 54293348

Gene position: 445863-445384 (Counterclockwise)

Preceding gene: 54293349

Following gene: 54293306

Centisome position: 13.33

GC content: 39.17

Gene sequence:

>480_bases
ATGGCAAGAGGAATAAATAAAGTAATACTTGTTGGTAATGTAGGGGCAGATCCTGATGTAAGGTATTTGCCTAACGGAAA
TGCTGTTACTACACTTTCAGTTGCTACCAGTGAAACATGGAAAGACAAAACGACAGGTGAAAAACAAGATAGAACTGAAT
GGCACAGAGTAGTCTGTTTTAATCGTCTGGGTGAAATAGCTGGAGAATACATTCGCAAAGGTTCCAAGCTATATGTCGAA
GGGAGCTTAAGAACAAGAAAATGGCAAGATCAACAGGGCCAAGATAGATATACAACTGAAATTGTTGCGTCTGACATTCA
AATGCTCGATAGCAAAGGAAGTAGCACAACTAATTACGACGACATGCCTTCATTTCAGGGAACGTCTACCCCTCAACAAG
CTTCAACAAAAAATCAAGTAACACCAACATCTACTGCACAAGATGCTTTTGATGAATTAGATGATGACATACCGTTTTAA

Upstream 100 bases:

>100_bases
ATCTACTATTTACCAATAACACCTTCTCTTTGGGCTGCTACGAAATAACTGCCAAATTATGTATAATACCTAACTAACTT
TCGCACAGGAGATGATTTCA

Downstream 100 bases:

>100_bases
ATGATTCAAATAAAAGCCCGCGTTAATGCGGGCTCAAAATATAGATTATAGCTATTAATCTAAAATTTACTCTTCAGTAT
CATCACTGATTACAGGTCTA

Product: single-strand binding protein (SSB) (helix-destabilizing protein)

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein [H]

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MARGINKVILVGNVGADPDVRYLPNGNAVTTLSVATSETWKDKTTGEKQDRTEWHRVVCFNRLGEIAGEYIRKGSKLYVE
GSLRTRKWQDQQGQDRYTTEIVASDIQMLDSKGSSTTNYDDMPSFQGTSTPQQASTKNQVTPTSTAQDAFDELDDDIPF

Sequences:

>Translated_159_residues
MARGINKVILVGNVGADPDVRYLPNGNAVTTLSVATSETWKDKTTGEKQDRTEWHRVVCFNRLGEIAGEYIRKGSKLYVE
GSLRTRKWQDQQGQDRYTTEIVASDIQMLDSKGSSTTNYDDMPSFQGTSTPQQASTKNQVTPTSTAQDAFDELDDDIPF
>Mature_158_residues
ARGINKVILVGNVGADPDVRYLPNGNAVTTLSVATSETWKDKTTGEKQDRTEWHRVVCFNRLGEIAGEYIRKGSKLYVEG
SLRTRKWQDQQGQDRYTTEIVASDIQMLDSKGSSTTNYDDMPSFQGTSTPQQASTKNQVTPTSTAQDAFDELDDDIPF

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=115, Percent_Identity=34.7826086956522, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1790494, Length=182, Percent_Identity=46.1538461538462, Blast_Score=165, Evalue=1e-42,
Organism=Drosophila melanogaster, GI85725234, Length=103, Percent_Identity=38.8349514563107, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647376, Length=103, Percent_Identity=38.8349514563107, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 17702; Mature: 17570

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARGINKVILVGNVGADPDVRYLPNGNAVTTLSVATSETWKDKTTGEKQDRTEWHRVVCF
CCCCCCEEEEEECCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
NRLGEIAGEYIRKGSKLYVEGSLRTRKWQDQQGQDRYTTEIVASDIQMLDSKGSSTTNYD
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
DMPSFQGTSTPQQASTKNQVTPTSTAQDAFDELDDDIPF
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARGINKVILVGNVGADPDVRYLPNGNAVTTLSVATSETWKDKTTGEKQDRTEWHRVVCF
CCCCCEEEEEECCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
NRLGEIAGEYIRKGSKLYVEGSLRTRKWQDQQGQDRYTTEIVASDIQMLDSKGSSTTNYD
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
DMPSFQGTSTPQQASTKNQVTPTSTAQDAFDELDDDIPF
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]