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The map label for this gene is rmlA1 [C]

Identifier: 54293300

GI number: 54293300

Start: 400652

End: 401314

Strand: Reverse

Name: rmlA1 [C]

Synonym: lpl0348

Alternate gene names: 54293300

Gene position: 401314-400652 (Counterclockwise)

Preceding gene: 54293301

Following gene: 54293297

Centisome position: 11.99

GC content: 40.57

Gene sequence:

>663_bases
ATGAAAACCGCTATGATTCTTGCAGCAGGACGTGGAGAACGATTACGCCCTTTAACCGACAAAATTCCTAAAGCACTTTG
TACGGTAAGAAACAAACCGTTAATTGAACACCATATCATTAACCTAGCCAATGCCGGCTTTGAACGATTGATAATCAACC
ATGCCTACCTGGGCGGACAAATTCGCCAATATATAGGAAATGGAAAACAATGGGGCTTAAATGTTATCTATTCTCCAGAA
CCGCCAGGAGGCCTTGAAACAGGGGGAGGGATTGTGAATGCCTTGCCTTTGCTGGGAGAAGAGCCATTTTTAACAGTAAA
TGCCGACATTTATACTGATTTTGATTTTGCCAAGCTGCAACTCAAAAATATTGATACATTTCATCTGCTTTTAATTCCCA
AAAATCCTTCTTTGCTTCATCATGGCGATTTTGGTTTAATCAATGGATCCCACTTAACCAATACAAATCAGGCTTACACT
TTTTCAGGTATTGCCTGCTATAACCCAAAGGTTTTTGCCAACTGCAGACAAGGACGGTATTCTGTTACCCCTTTACTTAG
AAAATATGTGGAACAAAATAAAGCCACCGGAAGTGTTCATTCAGGAATTTGGTATGACATAGGCTCATTCGATAGACTGC
AGGCAGCAAATCAGTTCACCTAA

Upstream 100 bases:

>100_bases
GAGACTTGCCTCTCACGTTAAAATATGCATTAGAATGCGCAGAAACATATGAAGAATTACACCCATTTTTTAATTTTCTG
CAAAAACGAGTTTATTTACC

Downstream 100 bases:

>100_bases
AAGCCAATCTTGGTTTTTAGGTGAACCAATATATTCCTATCTGATGGATTGAGTGGTTGGAGCTTCAGCACCGGATTCAA
TTTCTTGCCTGATTTCTTCT

Product: hypothetical protein

Products: dTDPglucose; Diphosphate [C]

Alternate protein names: Nucleotidyltransferase Family Protein; Nucleotidyl Transferase Family Protein; Nucleoside-Diphosphate-Sugar Pyrophosphorylase; Mannose-1-Phosphate Guanyltransferase; Nucleotidyl Transferase Superfamily; Nucleotidyltransferase; Sugar-Phosphate Nucleotidyl Transferase; Mannose-1-Phosphate Guanylyltransferase; Mannose-1-Phosphate Guanyltransferase-Related Protein; Nucleotidyltransferase Protein; Transaldolase AB; ADP-Glucose Pyrophosphorylase; Mannose-1-Phosphate Guanyltransferase Protein; Aminoglycoside Phosphotransferase; Phosphoglucomutase; Nucleotidyl Transferase Superfamily Protein; Nucleotidyl Transferase Protein; Sugar-Phosphate Nucleotide Transferase; Glucose-1-Phosphate Nucleotidyltransferase

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKTAMILAAGRGERLRPLTDKIPKALCTVRNKPLIEHHIINLANAGFERLIINHAYLGGQIRQYIGNGKQWGLNVIYSPE
PPGGLETGGGIVNALPLLGEEPFLTVNADIYTDFDFAKLQLKNIDTFHLLLIPKNPSLLHHGDFGLINGSHLTNTNQAYT
FSGIACYNPKVFANCRQGRYSVTPLLRKYVEQNKATGSVHSGIWYDIGSFDRLQAANQFT

Sequences:

>Translated_220_residues
MKTAMILAAGRGERLRPLTDKIPKALCTVRNKPLIEHHIINLANAGFERLIINHAYLGGQIRQYIGNGKQWGLNVIYSPE
PPGGLETGGGIVNALPLLGEEPFLTVNADIYTDFDFAKLQLKNIDTFHLLLIPKNPSLLHHGDFGLINGSHLTNTNQAYT
FSGIACYNPKVFANCRQGRYSVTPLLRKYVEQNKATGSVHSGIWYDIGSFDRLQAANQFT
>Mature_220_residues
MKTAMILAAGRGERLRPLTDKIPKALCTVRNKPLIEHHIINLANAGFERLIINHAYLGGQIRQYIGNGKQWGLNVIYSPE
PPGGLETGGGIVNALPLLGEEPFLTVNADIYTDFDFAKLQLKNIDTFHLLLIPKNPSLLHHGDFGLINGSHLTNTNQAYT
FSGIACYNPKVFANCRQGRYSVTPLLRKYVEQNKATGSVHSGIWYDIGSFDRLQAANQFT

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Drosophila melanogaster, GI21355443, Length=228, Percent_Identity=27.6315789473684, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644084, Length=228, Percent_Identity=27.6315789473684, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.24 [C]

Molecular weight: Translated: 24359; Mature: 24359

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAMILAAGRGERLRPLTDKIPKALCTVRNKPLIEHHIINLANAGFERLIINHAYLGGQ
CCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHCHH
IRQYIGNGKQWGLNVIYSPEPPGGLETGGGIVNALPLLGEEPFLTVNADIYTDFDFAKLQ
HHHHHCCCCEECEEEEECCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCEEECCCEEEEE
LKNIDTFHLLLIPKNPSLLHHGDFGLINGSHLTNTNQAYTFSGIACYNPKVFANCRQGRY
ECCCCEEEEEEEECCCCEEECCCEEEECCCEECCCCCEEEECCEEEECCCEEECCCCCCE
SVTPLLRKYVEQNKATGSVHSGIWYDIGSFDRLQAANQFT
EHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHCCCCC
>Mature Secondary Structure
MKTAMILAAGRGERLRPLTDKIPKALCTVRNKPLIEHHIINLANAGFERLIINHAYLGGQ
CCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHCHH
IRQYIGNGKQWGLNVIYSPEPPGGLETGGGIVNALPLLGEEPFLTVNADIYTDFDFAKLQ
HHHHHCCCCEECEEEEECCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCEEECCCEEEEE
LKNIDTFHLLLIPKNPSLLHHGDFGLINGSHLTNTNQAYTFSGIACYNPKVFANCRQGRY
ECCCCEEEEEEEECCCCEEECCCEEEECCCEECCCCCEEEECCEEEECCCEEECCCCCCE
SVTPLLRKYVEQNKATGSVHSGIWYDIGSFDRLQAANQFT
EHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTTP; D-Glucose 1-phosphate; H+ [C]

Specific reaction: dTTP + D-Glucose 1-phosphate + H+ --> dTDPglucose + Diphosphate [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA