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The map label for this gene is corA [H]

Identifier: 54293271

GI number: 54293271

Start: 364018

End: 365070

Strand: Reverse

Name: corA [H]

Synonym: lpl0319

Alternate gene names: 54293271

Gene position: 365070-364018 (Counterclockwise)

Preceding gene: 54293276

Following gene: 54293269

Centisome position: 10.91

GC content: 34.0

Gene sequence:

>1053_bases
TTGTCAATATCATTTAAGTCTCCTATTCTTAAACTATATGAGGAAATTAATCGTATAGGGATAAGCATTGAAATGCATTC
GTTTGATTCAATCGCCGTTGAATTTGATTTAAAAAATCATAGTATGCAAAAAATTGCGATTGAGGATTTAAATATTGATT
ATCAGGATAAAGATAAAATTTATTGGATACATAGCAATTTAAACCAAAAAAATATCTTTAAAAAATTGCGAGAGAAATTA
CGATTACCCGAGCAAGTGATTCAATTGTGTGGAGAAAAAGACAATAGATCCACAACCATAGAGATCGATGAAGCGCTCAC
ATTGCAAATTCAAGGCTTGTGCTCAATGAAGTTGAATGACAGTTATGATGCTGATTTTGGCAATTTGATTATTCATCTTA
CACCCAATTATTGCTTTACTGCTTCTAAAACACTGTCGTCTGTCTTGTTTGATCTGTTAAAAAGCTGCCCAAAATCCTTG
CCCTATGCTAAAACATCTTGTTTTTTGTTATTTTTGCTTCTGGAAGGAGTAATTAATGATTATGCCAAGATACATTTAGC
TTATGAAGAATTAGCCGATCAATTCGACGCACAAGTTCGTACCACTAATAAAAACACCTATTCGCAAGTTTTGGAATTAA
AGCATGGTGTCATGAAAATTAAGCGTTATACCATTGCAATAAGAGAAATATTAATGCGTCTCACCAGCCGAAATATTTTA
GTCATCTCAGAGCAGTGTCGAACCTCCTTATATAATTTATCAAATCACTGCCACCTTATTGTCAATGAAGTAGATTCTCT
TCGCGATATGTTAAATGGCTTATTGGGACAAATCGATAACCAGTTGATGCAAAACATGAATGAAACCATGAAAGTATTAA
CCGCCTTCGCAGCCATATTCTTGCCTTTAAGTTTAATTACCGGGATTTATGGGATGAATTTCTACTGGATACCGGAATTA
GGTTGGAAATATGGCTATTTTTGGGCACTTGGATTGCTCGTGCTGTGTGCTCTGCTATTGTTTTTAATTTTCAGAAAAAA
GAAGTGGTTTTAG

Upstream 100 bases:

>100_bases
TATAGAGATAGAATTAAAACAAGGCAACAGCCAAACAGAAGACCAGCTAGCCACGAGATACTCGCAGTCTATTGGAAAAC
CCGGGGTATTTAAAAATTGT

Downstream 100 bases:

>100_bases
GCCAATTCATAGAACTAACCGACACTAAAATTTTCCCCTACCCCTTTGACTACATGCCACATACATTCAGCCCCATGATA
ACTAAGCGCCTGAATATCCG

Product: hypothetical protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSISFKSPILKLYEEINRIGISIEMHSFDSIAVEFDLKNHSMQKIAIEDLNIDYQDKDKIYWIHSNLNQKNIFKKLREKL
RLPEQVIQLCGEKDNRSTTIEIDEALTLQIQGLCSMKLNDSYDADFGNLIIHLTPNYCFTASKTLSSVLFDLLKSCPKSL
PYAKTSCFLLFLLLEGVINDYAKIHLAYEELADQFDAQVRTTNKNTYSQVLELKHGVMKIKRYTIAIREILMRLTSRNIL
VISEQCRTSLYNLSNHCHLIVNEVDSLRDMLNGLLGQIDNQLMQNMNETMKVLTAFAAIFLPLSLITGIYGMNFYWIPEL
GWKYGYFWALGLLVLCALLLFLIFRKKKWF

Sequences:

>Translated_350_residues
MSISFKSPILKLYEEINRIGISIEMHSFDSIAVEFDLKNHSMQKIAIEDLNIDYQDKDKIYWIHSNLNQKNIFKKLREKL
RLPEQVIQLCGEKDNRSTTIEIDEALTLQIQGLCSMKLNDSYDADFGNLIIHLTPNYCFTASKTLSSVLFDLLKSCPKSL
PYAKTSCFLLFLLLEGVINDYAKIHLAYEELADQFDAQVRTTNKNTYSQVLELKHGVMKIKRYTIAIREILMRLTSRNIL
VISEQCRTSLYNLSNHCHLIVNEVDSLRDMLNGLLGQIDNQLMQNMNETMKVLTAFAAIFLPLSLITGIYGMNFYWIPEL
GWKYGYFWALGLLVLCALLLFLIFRKKKWF
>Mature_349_residues
SISFKSPILKLYEEINRIGISIEMHSFDSIAVEFDLKNHSMQKIAIEDLNIDYQDKDKIYWIHSNLNQKNIFKKLREKLR
LPEQVIQLCGEKDNRSTTIEIDEALTLQIQGLCSMKLNDSYDADFGNLIIHLTPNYCFTASKTLSSVLFDLLKSCPKSLP
YAKTSCFLLFLLLEGVINDYAKIHLAYEELADQFDAQVRTTNKNTYSQVLELKHGVMKIKRYTIAIREILMRLTSRNILV
ISEQCRTSLYNLSNHCHLIVNEVDSLRDMLNGLLGQIDNQLMQNMNETMKVLTAFAAIFLPLSLITGIYGMNFYWIPELG
WKYGYFWALGLLVLCALLLFLIFRKKKWF

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=63, Percent_Identity=38.0952380952381, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 40601; Mature: 40470

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISFKSPILKLYEEINRIGISIEMHSFDSIAVEFDLKNHSMQKIAIEDLNIDYQDKDKI
CCCCCCCHHHHHHHHHHHHEEEEEEECCCCEEEEEEECCCCHHEEEHHHCCCCCCCCCCE
YWIHSNLNQKNIFKKLREKLRLPEQVIQLCGEKDNRSTTIEIDEALTLQIQGLCSMKLND
EEEECCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEECCEEEEEEECCEEEECCC
SYDADFGNLIIHLTPNYCFTASKTLSSVLFDLLKSCPKSLPYAKTSCFLLFLLLEGVIND
CCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
YAKIHLAYEELADQFDAQVRTTNKNTYSQVLELKHGVMKIKRYTIAIREILMRLTSRNIL
HHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VISEQCRTSLYNLSNHCHLIVNEVDSLRDMLNGLLGQIDNQLMQNMNETMKVLTAFAAIF
EEEHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPLSLITGIYGMNFYWIPELGWKYGYFWALGLLVLCALLLFLIFRKKKWF
HHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SISFKSPILKLYEEINRIGISIEMHSFDSIAVEFDLKNHSMQKIAIEDLNIDYQDKDKI
CCCCCCHHHHHHHHHHHHEEEEEEECCCCEEEEEEECCCCHHEEEHHHCCCCCCCCCCE
YWIHSNLNQKNIFKKLREKLRLPEQVIQLCGEKDNRSTTIEIDEALTLQIQGLCSMKLND
EEEECCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEECCEEEEEEECCEEEECCC
SYDADFGNLIIHLTPNYCFTASKTLSSVLFDLLKSCPKSLPYAKTSCFLLFLLLEGVIND
CCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
YAKIHLAYEELADQFDAQVRTTNKNTYSQVLELKHGVMKIKRYTIAIREILMRLTSRNIL
HHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VISEQCRTSLYNLSNHCHLIVNEVDSLRDMLNGLLGQIDNQLMQNMNETMKVLTAFAAIF
EEEHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPLSLITGIYGMNFYWIPELGWKYGYFWALGLLVLCALLLFLIFRKKKWF
HHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]