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The map label for this gene is rpiA [H]

Identifier: 54293056

GI number: 54293056

Start: 110865

End: 111515

Strand: Direct

Name: rpiA [H]

Synonym: lpl0093

Alternate gene names: 54293056

Gene position: 110865-111515 (Clockwise)

Preceding gene: 54293055

Following gene: 54293057

Centisome position: 3.31

GC content: 40.4

Gene sequence:

>651_bases
GTGAGTGAGTTAAAAATCAAAGCAGCCAAAGCAGCTATAGCTTATATTGAAGATGATATGGTTATAGGTGTTGGAACAGG
CTCTACCGTTAATTTTTTTATAAAAGAACTGGCAGCAATCAAACATAAGATAGAGGCTTGTGTAGCCAGTTCAAAAGCAA
CCGAGGCATTGCTTCGGGCAGAAGGTATCCCTGTAATTGATTTAAATTCAGTACAGGATTTACCTATCTATGTTGATGGC
GCTGATGAAGTCAATGAACGCGGTGAAATGATAAAGGGGGGCGGAGGAGCTCTGACTCGGGAGAAAATTGTAGCGAATGT
AGCCACACAATTTATTTGTATTGTCGATGAATCCAAGGTTGTAAAACGTTTAGGGGAATTTCCCGTTGCTGTGGAAGTCA
TTCCAATGGCCCGTAGTTTTGTTGCACGACAAATTGTTAAATTAGGGGGAGACCCTGAATACAGAGAAGGCTTCATTACT
GATAATGGTAATATTATTCTGGACGTGTTTAATCTGAATTTCTCAACACCTATGGCCTTGGAAGACAGTCTTAATGTAAT
CCCGGGTGTCGTTGAAAATGGAGTGTTTGCCAAACGTTTGGCAGATAAAGTGTTAGTGGCTTCAGCAAGTGGTGTCAATA
ATTTAAAATAG

Upstream 100 bases:

>100_bases
TTGTTTTCTTTGCCTATGATGGGAAGTGTAGAGAGTTTAAATGTGTCAGTGGCGACTGGTGTTTCATTGTATGAAGTAAT
TAGGCAAAGAGGGCAATTTC

Downstream 100 bases:

>100_bases
CCGACTTGTATACGTTCATATCTCAAAACATTAATTGCCAATAATTTTATAGGTTCCTCAAAAATGGATACGCACAAGGT
TTTTGTAAATCGAATTATAA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSELKIKAAKAAIAYIEDDMVIGVGTGSTVNFFIKELAAIKHKIEACVASSKATEALLRAEGIPVIDLNSVQDLPIYVDG
ADEVNERGEMIKGGGGALTREKIVANVATQFICIVDESKVVKRLGEFPVAVEVIPMARSFVARQIVKLGGDPEYREGFIT
DNGNIILDVFNLNFSTPMALEDSLNVIPGVVENGVFAKRLADKVLVASASGVNNLK

Sequences:

>Translated_216_residues
MSELKIKAAKAAIAYIEDDMVIGVGTGSTVNFFIKELAAIKHKIEACVASSKATEALLRAEGIPVIDLNSVQDLPIYVDG
ADEVNERGEMIKGGGGALTREKIVANVATQFICIVDESKVVKRLGEFPVAVEVIPMARSFVARQIVKLGGDPEYREGFIT
DNGNIILDVFNLNFSTPMALEDSLNVIPGVVENGVFAKRLADKVLVASASGVNNLK
>Mature_215_residues
SELKIKAAKAAIAYIEDDMVIGVGTGSTVNFFIKELAAIKHKIEACVASSKATEALLRAEGIPVIDLNSVQDLPIYVDGA
DEVNERGEMIKGGGGALTREKIVANVATQFICIVDESKVVKRLGEFPVAVEVIPMARSFVARQIVKLGGDPEYREGFITD
NGNIILDVFNLNFSTPMALEDSLNVIPGVVENGVFAKRLADKVLVASASGVNNLK

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=229, Percent_Identity=34.9344978165939, Blast_Score=109, Evalue=2e-24,
Organism=Escherichia coli, GI1789280, Length=213, Percent_Identity=55.868544600939, Blast_Score=236, Evalue=7e-64,
Organism=Caenorhabditis elegans, GI17551758, Length=215, Percent_Identity=37.6744186046512, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6324669, Length=220, Percent_Identity=28.6363636363636, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281364072, Length=213, Percent_Identity=34.2723004694836, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23063; Mature: 22932

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELKIKAAKAAIAYIEDDMVIGVGTGSTVNFFIKELAAIKHKIEACVASSKATEALLRA
CCCCHHHHHHHEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGIPVIDLNSVQDLPIYVDGADEVNERGEMIKGGGGALTREKIVANVATQFICIVDESKV
CCCCEEECCCCCCCEEEECCCHHHHHCCCEEECCCCCHHHHHHHHHHHHHEEEEECCHHH
VKRLGEFPVAVEVIPMARSFVARQIVKLGGDPEYREGFITDNGNIILDVFNLNFSTPMAL
HHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCC
EDSLNVIPGVVENGVFAKRLADKVLVASASGVNNLK
CCCCCCCCHHHCCCHHHHHHHHHHEEEECCCCCCCC
>Mature Secondary Structure 
SELKIKAAKAAIAYIEDDMVIGVGTGSTVNFFIKELAAIKHKIEACVASSKATEALLRA
CCCHHHHHHHEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGIPVIDLNSVQDLPIYVDGADEVNERGEMIKGGGGALTREKIVANVATQFICIVDESKV
CCCCEEECCCCCCCEEEECCCHHHHHCCCEEECCCCCHHHHHHHHHHHHHEEEEECCHHH
VKRLGEFPVAVEVIPMARSFVARQIVKLGGDPEYREGFITDNGNIILDVFNLNFSTPMAL
HHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCC
EDSLNVIPGVVENGVFAKRLADKVLVASASGVNNLK
CCCCCCCCHHHCCCHHHHHHHHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA