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The map label for this gene is aatA [H]

Identifier: 54293036

GI number: 54293036

Start: 83521

End: 84699

Strand: Reverse

Name: aatA [H]

Synonym: lpl0073

Alternate gene names: 54293036

Gene position: 84699-83521 (Counterclockwise)

Preceding gene: 54293039

Following gene: 54293023

Centisome position: 2.53

GC content: 46.48

Gene sequence:

>1179_bases
ATGGATATCGCATTGGCAAAGCGTGTACAAAAAGTAAAACCTTCACCTACCCTTGCCGTAGCTGCAAAAGCAGCGCAGAT
GAAAGCCCAGGGGCTTGATATCATTGGCCTTGGAACTGGTGAACCTGATTTTGACACGCCGCAGCATATAAAGCTAGCCG
CCATCTCTGCTATTGAAGCAGGTGATACCAAATACACCGCTGTTGATGGGATAGTCGAACTAAAGGAAGCGGTTAAAAAC
AAATTCAAAAGAGACAATGAACTGGATTATCAACTCAATCAGATATTGGTCTCCGTAGGAGGTAAACAAAGCTGCTATAA
CCTCTGCCAAGCTTACCTTAACCCTGGCGATGAAGTCATCATCCCTGCTCCTTATTGGGTATCCTATCCTGACATGGTTT
TGCTGGCCGATGGTGTTCCTGTCATCATTGAAACGACTCCCGCGCAGCGTTATAAAATCAATGCACAACAATTGGAGCAA
GCCATCACTCCAAAAACACGAATGATTTTCCTGAACAGCCCTTCCAACCCCTCTGGAATAGCCTACACTCAGCAGGAGTT
AAAAGAATTGGGTGAGGTCTTGAAAAAACATCCACAGATACTGATTGCCACGGATGATATGTACGAACATATTCTCTGGA
GTCAAGCTTTTACAAATATACTCAATGCCTGCCCTGAATTATATGACAGAACGATCGTATTAAATGGCGTGTCCAAAGCT
TATGCCATGACAGGCTGGCGAATAGGCTATGCGGCCGGCCCTGCGCCATTAATCAATGCAATGAAAACCATTCAATCCCA
ATCCACATCCAATCCATGCTCCATAGCCCAAAGAGCGGCCGTAGCCGCTTTGAATGGCAGCAATGAAAGCATTGAAGAAA
TGGTCAACGCCTTCCATCAAAGGCACGACTACGTGGCCGATAGATTGCAAAGCATCGATGGCATAGAGGTCATCCCCGCC
GACGGAACTTTCTACATTTTTCCCAGTGTGCAGGCGATTATCGAAAAACGGGGTTACGCCAATGACATCGAATTTTCCGA
AAAATTGCTGAATGAAGTAGGTGTAGCACTGGTTCCAGGCTCCGCTTTCGGCACAGAAGGCTGCATCAGAATATCCTTCG
CCACCGGTATTGACACCCTGAAAGATGCCTTGAACCGGCTGCAACGTTTCTGCAGTTAA

Upstream 100 bases:

>100_bases
AGGTTGATCGCCGGCAGGTTGGTAATTTGAGTAAATTTTAAATAAGTCTTTCATATTTTATATTATATGCTAGTACCCCT
ATAATTCACAGGAGCAACAG

Downstream 100 bases:

>100_bases
AAAATATATTAAAAACCTCTTGATTCTCTCGCGGAATCGTTTTAAGATTCCGCCTCAATTCCCCGGTAGCTCAGTCGGTA
GAGCGGATGACTGTTAATCA

Product: hypothetical protein

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MDIALAKRVQKVKPSPTLAVAAKAAQMKAQGLDIIGLGTGEPDFDTPQHIKLAAISAIEAGDTKYTAVDGIVELKEAVKN
KFKRDNELDYQLNQILVSVGGKQSCYNLCQAYLNPGDEVIIPAPYWVSYPDMVLLADGVPVIIETTPAQRYKINAQQLEQ
AITPKTRMIFLNSPSNPSGIAYTQQELKELGEVLKKHPQILIATDDMYEHILWSQAFTNILNACPELYDRTIVLNGVSKA
YAMTGWRIGYAAGPAPLINAMKTIQSQSTSNPCSIAQRAAVAALNGSNESIEEMVNAFHQRHDYVADRLQSIDGIEVIPA
DGTFYIFPSVQAIIEKRGYANDIEFSEKLLNEVGVALVPGSAFGTEGCIRISFATGIDTLKDALNRLQRFCS

Sequences:

>Translated_392_residues
MDIALAKRVQKVKPSPTLAVAAKAAQMKAQGLDIIGLGTGEPDFDTPQHIKLAAISAIEAGDTKYTAVDGIVELKEAVKN
KFKRDNELDYQLNQILVSVGGKQSCYNLCQAYLNPGDEVIIPAPYWVSYPDMVLLADGVPVIIETTPAQRYKINAQQLEQ
AITPKTRMIFLNSPSNPSGIAYTQQELKELGEVLKKHPQILIATDDMYEHILWSQAFTNILNACPELYDRTIVLNGVSKA
YAMTGWRIGYAAGPAPLINAMKTIQSQSTSNPCSIAQRAAVAALNGSNESIEEMVNAFHQRHDYVADRLQSIDGIEVIPA
DGTFYIFPSVQAIIEKRGYANDIEFSEKLLNEVGVALVPGSAFGTEGCIRISFATGIDTLKDALNRLQRFCS
>Mature_392_residues
MDIALAKRVQKVKPSPTLAVAAKAAQMKAQGLDIIGLGTGEPDFDTPQHIKLAAISAIEAGDTKYTAVDGIVELKEAVKN
KFKRDNELDYQLNQILVSVGGKQSCYNLCQAYLNPGDEVIIPAPYWVSYPDMVLLADGVPVIIETTPAQRYKINAQQLEQ
AITPKTRMIFLNSPSNPSGIAYTQQELKELGEVLKKHPQILIATDDMYEHILWSQAFTNILNACPELYDRTIVLNGVSKA
YAMTGWRIGYAAGPAPLINAMKTIQSQSTSNPCSIAQRAAVAALNGSNESIEEMVNAFHQRHDYVADRLQSIDGIEVIPA
DGTFYIFPSVQAIIEKRGYANDIEFSEKLLNEVGVALVPGSAFGTEGCIRISFATGIDTLKDALNRLQRFCS

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=382, Percent_Identity=26.7015706806283, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI56713256, Length=382, Percent_Identity=26.7015706806283, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI95147551, Length=422, Percent_Identity=23.4597156398104, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI169881279, Length=422, Percent_Identity=23.4597156398104, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI169881281, Length=417, Percent_Identity=20.863309352518, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4507369, Length=402, Percent_Identity=23.6318407960199, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1786816, Length=369, Percent_Identity=28.4552845528455, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1788722, Length=373, Percent_Identity=28.1501340482574, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788627, Length=387, Percent_Identity=25.5813953488372, Blast_Score=122, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=393, Percent_Identity=28.7531806615776, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71994476, Length=393, Percent_Identity=28.7531806615776, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17567369, Length=332, Percent_Identity=26.2048192771084, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=336, Percent_Identity=22.9166666666667, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71981209, Length=367, Percent_Identity=22.6158038147139, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=396, Percent_Identity=25.5050505050505, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573069, Length=387, Percent_Identity=26.6149870801034, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24646114, Length=387, Percent_Identity=26.6149870801034, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI28573067, Length=387, Percent_Identity=26.6149870801034, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI28573065, Length=387, Percent_Identity=26.6149870801034, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=22.65625, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42825; Mature: 42825

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIALAKRVQKVKPSPTLAVAAKAAQMKAQGLDIIGLGTGEPDFDTPQHIKLAAISAIEA
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEHHHHHECC
GDTKYTAVDGIVELKEAVKNKFKRDNELDYQLNQILVSVGGKQSCYNLCQAYLNPGDEVI
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEE
IPAPYWVSYPDMVLLADGVPVIIETTPAQRYKINAQQLEQAITPKTRMIFLNSPSNPSGI
ECCCCCCCCCCEEEEECCCEEEEECCCCHHEECCHHHHHHHHCCCEEEEEEECCCCCCCC
AYTQQELKELGEVLKKHPQILIATDDMYEHILWSQAFTNILNACPELYDRTIVLNGVSKA
CHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHH
YAMTGWRIGYAAGPAPLINAMKTIQSQSTSNPCSIAQRAAVAALNGSNESIEEMVNAFHQ
HHHCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RHDYVADRLQSIDGIEVIPADGTFYIFPSVQAIIEKRGYANDIEFSEKLLNEVGVALVPG
HHHHHHHHHHCCCCCEEEECCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCEEEECC
SAFGTEGCIRISFATGIDTLKDALNRLQRFCS
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIALAKRVQKVKPSPTLAVAAKAAQMKAQGLDIIGLGTGEPDFDTPQHIKLAAISAIEA
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEHHHHHECC
GDTKYTAVDGIVELKEAVKNKFKRDNELDYQLNQILVSVGGKQSCYNLCQAYLNPGDEVI
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEE
IPAPYWVSYPDMVLLADGVPVIIETTPAQRYKINAQQLEQAITPKTRMIFLNSPSNPSGI
ECCCCCCCCCCEEEEECCCEEEEECCCCHHEECCHHHHHHHHCCCEEEEEEECCCCCCCC
AYTQQELKELGEVLKKHPQILIATDDMYEHILWSQAFTNILNACPELYDRTIVLNGVSKA
CHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHH
YAMTGWRIGYAAGPAPLINAMKTIQSQSTSNPCSIAQRAAVAALNGSNESIEEMVNAFHQ
HHHCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RHDYVADRLQSIDGIEVIPADGTFYIFPSVQAIIEKRGYANDIEFSEKLLNEVGVALVPG
HHHHHHHHHHCCCCCEEEECCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCEEEECC
SAFGTEGCIRISFATGIDTLKDALNRLQRFCS
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]