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The map label for this gene is degU [H]

Identifier: 54027465

GI number: 54027465

Start: 5820766

End: 5821434

Strand: Reverse

Name: degU [H]

Synonym: nfa54910

Alternate gene names: 54027465

Gene position: 5821434-5820766 (Counterclockwise)

Preceding gene: 54027466

Following gene: 54027464

Centisome position: 96.68

GC content: 72.2

Gene sequence:

>669_bases
ATGACCGAGGACGCTGCCCCCGGGACCATCACGGTGATGGTGGTCGACGACCACCCGATGTGGCGCGACGGCGTGTCCCG
CGACCTGGGCGAAGCCGGGTTCACGGTGGCCGCCACCGCCGACGGGGTGGGCTCGGCCACCCGGCGGGCGGCCGCGGTGC
GACCCACCGTGGTGCTGATGGACATGCAGTTGCCCGACGGCAACGGCGCCCAGGCCACCGCCGAGGTGCTGCGCGTCTCG
CCGGACAGCCGGGTGCTCGTGCTCTCGGCCTCCGCCGAACGCGACGACGTGCTCGAAGCCATCAAGGCGGGCGCCTCCGG
CTACCTGGTCAAGAGCGCCTCGGCCGCGGAACTGATCGAGGCGGTGCGCGCCACCGCCGCCGGACAGCCGGTGTTCACTC
CCGGCCTGGCGGGCCTGGTGCTGGGCGAATACCGCCGGATGGCCAGTGCCCCGGCCCGTCCCGACGAACCGCACCGGCCC
GCGCTGACCGAGCGCGAGACCGAGGTGCTGCGCATGGTGGCGAAAGGACTGTCCGCCAAACAGATCGCGGCCCGGCTCGG
CCTGAGCCACCGCACCGTGGAAAACCACGTGCAGGCCACACTGCGCAAACTGCAACTGGCGAACCGGGTGGAACTGACCC
GCTACGCGATCGAGCAGGGGCTCGAATAG

Upstream 100 bases:

>100_bases
CTCAGCGACGGCGGGGACGGCGAGGGCGTGGAATGGGAGTTCCGGGTGCCGCGCGGCTGAGCCCGGCTCTGGCACGATGA
ACAGGCGGGAGAGGAGTGCG

Downstream 100 bases:

>100_bases
CGGTCTCGCCGCGGGTCGGGGGGCGAATCAGGGATCGCCCTGATGCCGTGCGCGCGGGGTCGTCGGTAACCTCGATGGCA
TGGGCGGCCCCGAATCGGTA

Product: putative two-component system response regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTEDAAPGTITVMVVDDHPMWRDGVSRDLGEAGFTVAATADGVGSATRRAAAVRPTVVLMDMQLPDGNGAQATAEVLRVS
PDSRVLVLSASAERDDVLEAIKAGASGYLVKSASAAELIEAVRATAAGQPVFTPGLAGLVLGEYRRMASAPARPDEPHRP
ALTERETEVLRMVAKGLSAKQIAARLGLSHRTVENHVQATLRKLQLANRVELTRYAIEQGLE

Sequences:

>Translated_222_residues
MTEDAAPGTITVMVVDDHPMWRDGVSRDLGEAGFTVAATADGVGSATRRAAAVRPTVVLMDMQLPDGNGAQATAEVLRVS
PDSRVLVLSASAERDDVLEAIKAGASGYLVKSASAAELIEAVRATAAGQPVFTPGLAGLVLGEYRRMASAPARPDEPHRP
ALTERETEVLRMVAKGLSAKQIAARLGLSHRTVENHVQATLRKLQLANRVELTRYAIEQGLE
>Mature_221_residues
TEDAAPGTITVMVVDDHPMWRDGVSRDLGEAGFTVAATADGVGSATRRAAAVRPTVVLMDMQLPDGNGAQATAEVLRVSP
DSRVLVLSASAERDDVLEAIKAGASGYLVKSASAAELIEAVRATAAGQPVFTPGLAGLVLGEYRRMASAPARPDEPHRPA
LTERETEVLRMVAKGLSAKQIAARLGLSHRTVENHVQATLRKLQLANRVELTRYAIEQGLE

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=212, Percent_Identity=35.377358490566, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1788222, Length=215, Percent_Identity=32.093023255814, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787473, Length=202, Percent_Identity=33.1683168316832, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790102, Length=211, Percent_Identity=36.0189573459716, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1786747, Length=208, Percent_Identity=27.4038461538462, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=24.7572815533981, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23471; Mature: 23340

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEDAAPGTITVMVVDDHPMWRDGVSRDLGEAGFTVAATADGVGSATRRAAAVRPTVVLM
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCEEEEE
DMQLPDGNGAQATAEVLRVSPDSRVLVLSASAERDDVLEAIKAGASGYLVKSASAAELIE
EEECCCCCCHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCCHHHHHH
AVRATAAGQPVFTPGLAGLVLGEYRRMASAPARPDEPHRPALTERETEVLRMVAKGLSAK
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHH
QIAARLGLSHRTVENHVQATLRKLQLANRVELTRYAIEQGLE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEDAAPGTITVMVVDDHPMWRDGVSRDLGEAGFTVAATADGVGSATRRAAAVRPTVVLM
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCEEEEE
DMQLPDGNGAQATAEVLRVSPDSRVLVLSASAERDDVLEAIKAGASGYLVKSASAAELIE
EEECCCCCCHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCCHHHHHH
AVRATAAGQPVFTPGLAGLVLGEYRRMASAPARPDEPHRPALTERETEVLRMVAKGLSAK
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHH
QIAARLGLSHRTVENHVQATLRKLQLANRVELTRYAIEQGLE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]