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The map label for this gene is dcd

Identifier: 54027403

GI number: 54027403

Start: 5747984

End: 5748583

Strand: Reverse

Name: dcd

Synonym: nfa54290

Alternate gene names: 54027403

Gene position: 5748583-5747984 (Counterclockwise)

Preceding gene: 54027406

Following gene: 54027402

Centisome position: 95.47

GC content: 68.17

Gene sequence:

>600_bases
GTGCTGCTTTCCGATCGCGACATCCGTGCGGAGATCGCCGCTGGGCGTCTCGGGGTCGAGCCGCTGCTGGAGAACCTCAT
CCAGCCGTCCAGCATCGACGTGCGACTGGACCGGATGTTCCGCGTCTTCGACAACTCGCGCTACACCCACATCGATCCGG
CGCAGCGCCAGGACGAACTCACCAGCCTGGTCGAGCCGGGCGAGGGCGAACCCTTCGTCCTGCATCCCGGCGAGTTCGTG
CTGGGCTCCACCCTCGAGGTCTGCACACTGCCCGACGACCTGGCCGGGCGCTTGGAAGGCAAGTCCAGCCTGGGCAGGCT
CGGGCTGCTCACGCACTCCACGGCCGGGTTCATCGACCCGGGATTCAGCGGGCACATCACGCTCGAGCTGTCCAACGTGG
CGAACCTGCCGATCACGTTGTGGCCGGGGATGAAGATCGGCCAGCTGTGCCTGTTCCGGCTGAGCAGCCCCGCGGAGCAC
CCCTATGGCAGTGCCGCGGCCGGATCGAAGTACCAGGGTCAGCGCGGGCCGACGCCCTCGCGCTCCTACCTCAACTTCCC
GCTGCCCTCCGACGCCGTCGACGCCGTCGAATCCCGCTGA

Upstream 100 bases:

>100_bases
GGGCGGCCTGCGTGGTGACACTGCGCTGCCGCCTCCGGCCGCTGACCCGCTCAGGCTGTGCGGGCGTCGCGCGGATCAGG
GCGGACGCTACGCTCGTGGC

Downstream 100 bases:

>100_bases
CGCCGTCGGGTCTGGCTGATGCCGTCGGATTCTTGTCGACGCTGTCGGGTCTCTGCTGTCGCCGGCGACACCCGTTGTCG
CTGTCGAGTCCTCGCTGTCG

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MLLSDRDIRAEIAAGRLGVEPLLENLIQPSSIDVRLDRMFRVFDNSRYTHIDPAQRQDELTSLVEPGEGEPFVLHPGEFV
LGSTLEVCTLPDDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLCLFRLSSPAEH
PYGSAAAGSKYQGQRGPTPSRSYLNFPLPSDAVDAVESR

Sequences:

>Translated_199_residues
MLLSDRDIRAEIAAGRLGVEPLLENLIQPSSIDVRLDRMFRVFDNSRYTHIDPAQRQDELTSLVEPGEGEPFVLHPGEFV
LGSTLEVCTLPDDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLCLFRLSSPAEH
PYGSAAAGSKYQGQRGPTPSRSYLNFPLPSDAVDAVESR
>Mature_199_residues
MLLSDRDIRAEIAAGRLGVEPLLENLIQPSSIDVRLDRMFRVFDNSRYTHIDPAQRQDELTSLVEPGEGEPFVLHPGEFV
LGSTLEVCTLPDDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLCLFRLSSPAEH
PYGSAAAGSKYQGQRGPTPSRSYLNFPLPSDAVDAVESR

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=191, Percent_Identity=45.0261780104712, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_NOCFA (Q5YNG0)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_121645.1
- HSSP:   P28248
- ProteinModelPortal:   Q5YNG0
- SMR:   Q5YNG0
- GeneID:   3109810
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa54290
- NMPDR:   fig|247156.1.peg.5217
- HOGENOM:   HBG553199
- OMA:   FSGHVTL
- ProtClustDB:   PRK00416
- BioCyc:   NFAR247156:NFA54290-MONOMER
- BRENDA:   3.5.4.13
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 21595; Mature: 21595

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSDRDIRAEIAAGRLGVEPLLENLIQPSSIDVRLDRMFRVFDNSRYTHIDPAQRQDEL
CCCCCCCCHHHHHCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEECCCHHHHHHH
TSLVEPGEGEPFVLHPGEFVLGSTLEVCTLPDDLAGRLEGKSSLGRLGLLTHSTAGFIDP
HHHHCCCCCCEEEECCCCEEECCCEEEEECCHHHHHHCCCCCCCCEEEEEECCCCCCCCC
GFSGHITLELSNVANLPITLWPGMKIGQLCLFRLSSPAEHPYGSAAAGSKYQGQRGPTPS
CCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
RSYLNFPLPSDAVDAVESR
CCEEECCCCCHHHHHHHCC
>Mature Secondary Structure
MLLSDRDIRAEIAAGRLGVEPLLENLIQPSSIDVRLDRMFRVFDNSRYTHIDPAQRQDEL
CCCCCCCCHHHHHCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEECCCHHHHHHH
TSLVEPGEGEPFVLHPGEFVLGSTLEVCTLPDDLAGRLEGKSSLGRLGLLTHSTAGFIDP
HHHHCCCCCCEEEECCCCEEECCCEEEEECCHHHHHHCCCCCCCCEEEEEECCCCCCCCC
GFSGHITLELSNVANLPITLWPGMKIGQLCLFRLSSPAEHPYGSAAAGSKYQGQRGPTPS
CCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
RSYLNFPLPSDAVDAVESR
CCEEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA