BacMap

Definition	Nocardia farcinica IFM 10152 chromosome, complete genome.
Accession	NC_006361
Length	6,021,225

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The map label for this gene is ucpA [C]

Identifier: 54027373

GI number: 54027373

Start: 5701915

End: 5702727

Strand: Reverse

Name: ucpA [C]

Synonym: nfa53990

Alternate gene names: 54027373

Gene position: 5702727-5701915 (Counterclockwise)

Preceding gene: 54027374

Following gene: 54027372

Centisome position: 94.71

GC content: 70.36

Gene sequence:

>813_bases
ATGACCGACAGTCCCGCCCCCGCACGCCTGCCCGGTGCCACCCGGCCCGTCGCCCTGATCACCGGACCCACCTCCGGCAT
CGGTCACGGCTACGCCACCCGACTGGCCTCGCTCGGCTACGACCTGGTGCTCGTCGCCCGTGACGCAGACCGGCTGCGCG
ACCTGGCCGCCGAGCTGGAACGCCGATACGCCACCCGCTCGGAGGTGCTCACCGCCGACCTGGCCGTGGCGCACGACCGT
GAGCGGGTCGCCGCGCGGGCCGCCGACGGCATCGAATTCCTCGTCAACAACGCGGGATTCGCGCACTCCGGCGAATTCTG
GACGTTGCCCTACGAGCAGCTGCAGGCCCAGCTCGACGTCAACGTCACCGCCGTGCTGCAACTCACCCACGCCGCGCTAC
CCGCCATGATCGCCGCCGCCAAGGGGTCGATCGTCAACGTCGCCAGTGTCGCGGGCCTGATCCCCGGCCGCGGCTCGACC
TATTCGGCCTCCAAGGCCTACGTCGTATCCTTCACCGAGGGGTTGGCCGGCGGACTCGCCGGAACCGGTGTGCGGATCCA
GGCGCTGTGCCCGGGGTTCGTGCGCACCGAGTTCCATCGGCGGGCAGGCATCGAGATGTCCTCGCTGCCCGAGCCGTTGT
GGCTCTCGGTCGACCAGGTCGTCAGCGGCTCGCTGCGCGATCTGGACGCCGACCGCGTGATCAGCGTGCCCGGCGTGCAG
TACAAGGTGCTCACCACCGCGGCCGGACTCATCCCGCGGGCCCTGCAGGTCCGAATGAACCGGGGCCTGTTCAACTCACG
CGGAAGGACATAG

Upstream 100 bases:

>100_bases
CGGGGAGCGCCCGGGTGGCCCGTTCCACCCCGGCTTCCGCCCCTACCAGGGTCCTGTCCCGCAGTGACCGCCCCGACGCA
CCGCTGATCGGATTGCCTCG

Downstream 100 bases:

>100_bases
ACGACAAATGATGGATCAGGCGAGGGTCACGCGGCCCGAGCTGACCGGCGGCGACCGCGACGCGCTGGCCGCGCTGGTGC
GCGAGCTGGCCGTCGTGCAC

Product: putative short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTDSPAPARLPGATRPVALITGPTSGIGHGYATRLASLGYDLVLVARDADRLRDLAAELERRYATRSEVLTADLAVAHDR
ERVAARAADGIEFLVNNAGFAHSGEFWTLPYEQLQAQLDVNVTAVLQLTHAALPAMIAAAKGSIVNVASVAGLIPGRGST
YSASKAYVVSFTEGLAGGLAGTGVRIQALCPGFVRTEFHRRAGIEMSSLPEPLWLSVDQVVSGSLRDLDADRVISVPGVQ
YKVLTTAAGLIPRALQVRMNRGLFNSRGRT

Sequences:

>Translated_270_residues
MTDSPAPARLPGATRPVALITGPTSGIGHGYATRLASLGYDLVLVARDADRLRDLAAELERRYATRSEVLTADLAVAHDR
ERVAARAADGIEFLVNNAGFAHSGEFWTLPYEQLQAQLDVNVTAVLQLTHAALPAMIAAAKGSIVNVASVAGLIPGRGST
YSASKAYVVSFTEGLAGGLAGTGVRIQALCPGFVRTEFHRRAGIEMSSLPEPLWLSVDQVVSGSLRDLDADRVISVPGVQ
YKVLTTAAGLIPRALQVRMNRGLFNSRGRT
>Mature_269_residues
TDSPAPARLPGATRPVALITGPTSGIGHGYATRLASLGYDLVLVARDADRLRDLAAELERRYATRSEVLTADLAVAHDRE
RVAARAADGIEFLVNNAGFAHSGEFWTLPYEQLQAQLDVNVTAVLQLTHAALPAMIAAAKGSIVNVASVAGLIPGRGSTY
SASKAYVVSFTEGLAGGLAGTGVRIQALCPGFVRTEFHRRAGIEMSSLPEPLWLSVDQVVSGSLRDLDADRVISVPGVQY
KVLTTAAGLIPRALQVRMNRGLFNSRGRT

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=202, Percent_Identity=30.6930693069307, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI226371731, Length=185, Percent_Identity=31.3513513513514, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4557649, Length=185, Percent_Identity=34.0540540540541, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI32483357, Length=210, Percent_Identity=34.7619047619048, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI142976729, Length=256, Percent_Identity=30.859375, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI40254992, Length=189, Percent_Identity=31.7460317460317, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI210032110, Length=250, Percent_Identity=29.6, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI40807363, Length=234, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI31542939, Length=190, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI119392083, Length=221, Percent_Identity=31.6742081447964, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI225579078, Length=226, Percent_Identity=30.9734513274336, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI126723191, Length=205, Percent_Identity=31.7073170731707, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=141, Percent_Identity=29.7872340425532, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=31.6062176165803, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=29.5918367346939, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI5031737, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4503817, Length=180, Percent_Identity=32.7777777777778, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI186928839, Length=229, Percent_Identity=33.1877729257642, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI126723750, Length=200, Percent_Identity=32, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI150247226, Length=194, Percent_Identity=32.4742268041237, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082100, Length=199, Percent_Identity=37.1859296482412, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787820, Length=188, Percent_Identity=33.5106382978723, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1786701, Length=198, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787335, Length=196, Percent_Identity=27.0408163265306, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790717, Length=191, Percent_Identity=29.8429319371728, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI2367175, Length=199, Percent_Identity=30.6532663316583, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082160, Length=184, Percent_Identity=23.9130434782609, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789208, Length=188, Percent_Identity=29.7872340425532, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=195, Percent_Identity=37.4358974358974, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=194, Percent_Identity=35.0515463917526, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=202, Percent_Identity=30.6930693069307, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193203115, Length=241, Percent_Identity=29.8755186721992, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=241, Percent_Identity=29.8755186721992, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=210, Percent_Identity=30.952380952381, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=216, Percent_Identity=30.5555555555556, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=206, Percent_Identity=27.1844660194175, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=220, Percent_Identity=30.4545454545455, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560176, Length=194, Percent_Identity=29.3814432989691, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=268, Percent_Identity=26.4925373134328, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=202, Percent_Identity=30.1980198019802, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=196, Percent_Identity=29.5918367346939, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=186, Percent_Identity=32.258064516129, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=182, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=214, Percent_Identity=29.4392523364486, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI212646214, Length=196, Percent_Identity=32.1428571428571, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17557668, Length=198, Percent_Identity=29.7979797979798, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=210, Percent_Identity=29.5238095238095, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=218, Percent_Identity=29.3577981651376, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559552, Length=194, Percent_Identity=27.8350515463918, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=195, Percent_Identity=30.2564102564103, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=191, Percent_Identity=30.8900523560209, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=196, Percent_Identity=29.5918367346939, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=192, Percent_Identity=27.0833333333333, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=213, Percent_Identity=31.924882629108, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=198, Percent_Identity=31.3131313131313, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=193, Percent_Identity=28.4974093264249, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=35.7142857142857, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319635, Length=228, Percent_Identity=29.3859649122807, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357041, Length=204, Percent_Identity=36.2745098039216, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571526, Length=194, Percent_Identity=37.6288659793814, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24644339, Length=202, Percent_Identity=34.1584158415842, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI23397609, Length=193, Percent_Identity=37.8238341968912, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24584748, Length=186, Percent_Identity=36.5591397849462, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=36.5591397849462, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=34.2245989304813, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24584744, Length=187, Percent_Identity=34.2245989304813, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24640442, Length=192, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24584752, Length=204, Percent_Identity=34.3137254901961, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=30.1020408163265, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24651139, Length=194, Percent_Identity=32.9896907216495, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639444, Length=187, Percent_Identity=29.9465240641711, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643142, Length=183, Percent_Identity=33.879781420765, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24581726, Length=212, Percent_Identity=27.3584905660377, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358495, Length=203, Percent_Identity=30.0492610837438, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007238, Length=169, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=200, Percent_Identity=30.5, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28572; Mature: 28441

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSPAPARLPGATRPVALITGPTSGIGHGYATRLASLGYDLVLVARDADRLRDLAAELE
CCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHH
RRYATRSEVLTADLAVAHDRERVAARAADGIEFLVNNAGFAHSGEFWTLPYEQLQAQLDV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHEEECCCCCCCCCCEEECCHHHHHHHHCC
NVTAVLQLTHAALPAMIAAAKGSIVNVASVAGLIPGRGSTYSASKAYVVSFTEGLAGGLA
CHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCCCCCCCCCCCEEEEEECHHHHCCCC
GTGVRIQALCPGFVRTEFHRRAGIEMSSLPEPLWLSVDQVVSGSLRDLDADRVISVPGVQ
CCCEEEEEECCHHHHHHHHHHHCCCHHHCCCHHHEEHHHHHCCCHHCCCCCCEEECCCCE
YKVLTTAAGLIPRALQVRMNRGLFNSRGRT
EEHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TDSPAPARLPGATRPVALITGPTSGIGHGYATRLASLGYDLVLVARDADRLRDLAAELE
CCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHH
RRYATRSEVLTADLAVAHDRERVAARAADGIEFLVNNAGFAHSGEFWTLPYEQLQAQLDV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHEEECCCCCCCCCCEEECCHHHHHHHHCC
NVTAVLQLTHAALPAMIAAAKGSIVNVASVAGLIPGRGSTYSASKAYVVSFTEGLAGGLA
CHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCCCCCCCCCCCEEEEEECHHHHCCCC
GTGVRIQALCPGFVRTEFHRRAGIEMSSLPEPLWLSVDQVVSGSLRDLDADRVISVPGVQ
CCCEEEEEECCHHHHHHHHHHHCCCHHHCCCHHHEEHHHHHCCCHHCCCCCCEEECCCCE
YKVLTTAAGLIPRALQVRMNRGLFNSRGRT
EEHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA