Click here to switch to the map view.

The map label for this gene is fadE45 [H]

Identifier: 54027305

GI number: 54027305

Start: 5634785

End: 5635939

Strand: Reverse

Name: fadE45 [H]

Synonym: nfa53310

Alternate gene names: 54027305

Gene position: 5635939-5634785 (Counterclockwise)

Preceding gene: 54027306

Following gene: 54027304

Centisome position: 93.6

GC content: 68.92

Gene sequence:

>1155_bases
ATGAATGTCGGTCCGTGGAACACTCCCGAACGCCGCGAATTGCGCGCCACCGTGCGCGGATTCGTCGAGCGGGAGGTGCT
GCCCTACCTCGACGACTGGGAACGCGAGGGCGAGATCCCGCGCGAGCTGCACAAGAAGGCGGGTGCGCTGGGACTGCTCG
GTATCCAGTTCCCCGAGTCGGCCGGCGGCGCCGGGGGTGACGCGCTGGATTCGGTGATCGTCTGCGAGGAGATGCACCAG
GCGGGTGCCTCGGGTGGGCTGTTCGCCTCGCTGTTCACCTGCGGTATCGCGGTACCGCACATCATCGCCTCCGGCAACAC
CGATCTCATCGAGCGGTTCGCCAAGCCCACGCTCGCGGGCGAGAAGATCGGTTCGCTGGCCATCACCGAGCCCGGCGGCG
GCTCCGACGTCGGCCACCTCACCACCACCGCGCGCCGCGACGGTGACCACTACATCGTCAACGGCGCCAAGACCTACATC
ACCTCCGGGTGCCGCGCCGACTTCGTGGTCACCGCGGTCCGCACCGGCGGGCCGGGCTCGGCGGGCATCTCGCTGCTGGT
GGTGGAGAAGGACACGCCGGGTTTCACCGTGAGCCGCAAGCTCGACAAGATGGGCTGGCGGGCCTCCGACACCGCCGAAC
TGTCGTATGTGGACGTGCGGGTCCCGGTGGAAAACCTGGTGGGGCAGGAGAATTCGGGCTCCTACCAGATCGCGGCCGCG
TTCGTCAGCGAGCGGGTCGGGCTGGCCGTGCAGGCCTACGCCCAAGCGCAGCGCTGCCTGGACCTCACCCTGGAGTGGGT
GCGCAACCGCGAGACCTTCGGCCGTCCGCTCATCAGCAGGCAGGCCGTGCAGAACACGGTGACCGAGATGGCGCGGCGCA
TCGACGTCGCCCGCGTCTACACCCGCGAGGTCGCCCGGCGCAGCGCCGAGGGCGAGACCGATCTGATCGCCGAGGTCTGC
TTCGCCAAGAACACCGCCGTGGAGGCCGCCGAATGGGTGGCCCACCAAGCCGTCCAGCTCTTCGGCGGTCTGGGCTACAT
GCGTGAATCCGAGGTGGAGCGCCAGTACCGCGACATCCGCATCCTCGGTATCGGCGGCGGCACCACCGAGATCCTGACCG
GCCTGGCGGCCAAGCGATTGGGGTACCAGTCATGA

Upstream 100 bases:

>100_bases
GCAAGGGCGTGGCCTACCAGGCCCGCTTCGATCCGCAGGCCAAGGGACTCGGCGAATGGCTGCGGTCCCGTCACCTCGAT
ATCCCCGTGGAGCTGCTGTC

Downstream 100 bases:

>100_bases
CGATCCTGCGCAGCACCCTCGACAGCGCGGCACCGGAATACACCGCCGCCGCCGAGGCGATGACCACCAAACTCACCGAG
ATCGAAGCCGAATTCGCCAA

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNVGPWNTPERRELRATVRGFVEREVLPYLDDWEREGEIPRELHKKAGALGLLGIQFPESAGGAGGDALDSVIVCEEMHQ
AGASGGLFASLFTCGIAVPHIIASGNTDLIERFAKPTLAGEKIGSLAITEPGGGSDVGHLTTTARRDGDHYIVNGAKTYI
TSGCRADFVVTAVRTGGPGSAGISLLVVEKDTPGFTVSRKLDKMGWRASDTAELSYVDVRVPVENLVGQENSGSYQIAAA
FVSERVGLAVQAYAQAQRCLDLTLEWVRNRETFGRPLISRQAVQNTVTEMARRIDVARVYTREVARRSAEGETDLIAEVC
FAKNTAVEAAEWVAHQAVQLFGGLGYMRESEVERQYRDIRILGIGGGTTEILTGLAAKRLGYQS

Sequences:

>Translated_384_residues
MNVGPWNTPERRELRATVRGFVEREVLPYLDDWEREGEIPRELHKKAGALGLLGIQFPESAGGAGGDALDSVIVCEEMHQ
AGASGGLFASLFTCGIAVPHIIASGNTDLIERFAKPTLAGEKIGSLAITEPGGGSDVGHLTTTARRDGDHYIVNGAKTYI
TSGCRADFVVTAVRTGGPGSAGISLLVVEKDTPGFTVSRKLDKMGWRASDTAELSYVDVRVPVENLVGQENSGSYQIAAA
FVSERVGLAVQAYAQAQRCLDLTLEWVRNRETFGRPLISRQAVQNTVTEMARRIDVARVYTREVARRSAEGETDLIAEVC
FAKNTAVEAAEWVAHQAVQLFGGLGYMRESEVERQYRDIRILGIGGGTTEILTGLAAKRLGYQS
>Mature_384_residues
MNVGPWNTPERRELRATVRGFVEREVLPYLDDWEREGEIPRELHKKAGALGLLGIQFPESAGGAGGDALDSVIVCEEMHQ
AGASGGLFASLFTCGIAVPHIIASGNTDLIERFAKPTLAGEKIGSLAITEPGGGSDVGHLTTTARRDGDHYIVNGAKTYI
TSGCRADFVVTAVRTGGPGSAGISLLVVEKDTPGFTVSRKLDKMGWRASDTAELSYVDVRVPVENLVGQENSGSYQIAAA
FVSERVGLAVQAYAQAQRCLDLTLEWVRNRETFGRPLISRQAVQNTVTEMARRIDVARVYTREVARRSAEGETDLIAEVC
FAKNTAVEAAEWVAHQAVQLFGGLGYMRESEVERQYRDIRILGIGGGTTEILTGLAAKRLGYQS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=37.8306878306878, Blast_Score=251, Evalue=8e-67,
Organism=Homo sapiens, GI4557233, Length=366, Percent_Identity=37.9781420765027, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=35.2, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI7656849, Length=371, Percent_Identity=32.8840970350404, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI226958414, Length=379, Percent_Identity=35.3562005277045, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=31.4666666666667, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI4557231, Length=368, Percent_Identity=32.3369565217391, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI187960098, Length=368, Percent_Identity=32.3369565217391, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI21361497, Length=360, Percent_Identity=31.6666666666667, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI76496475, Length=334, Percent_Identity=29.940119760479, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI4557235, Length=334, Percent_Identity=29.940119760479, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI4503943, Length=363, Percent_Identity=24.7933884297521, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI211971008, Length=404, Percent_Identity=25.7425742574257, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI48976061, Length=403, Percent_Identity=25.3101736972705, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI7669494, Length=371, Percent_Identity=24.5283018867925, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38505218, Length=408, Percent_Identity=23.0392156862745, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI87081958, Length=378, Percent_Identity=29.3650793650794, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1786223, Length=348, Percent_Identity=27.5862068965517, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87082384, Length=264, Percent_Identity=26.8939393939394, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=35.4497354497354, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17534899, Length=368, Percent_Identity=33.4239130434783, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17533517, Length=362, Percent_Identity=30.1104972375691, Blast_Score=197, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI17569725, Length=369, Percent_Identity=32.520325203252, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17505929, Length=370, Percent_Identity=31.6216216216216, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=31.3513513513514, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17551932, Length=371, Percent_Identity=30.7277628032345, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17538396, Length=369, Percent_Identity=30.6233062330623, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17506239, Length=379, Percent_Identity=30.3430079155673, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71990804, Length=275, Percent_Identity=33.8181818181818, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI71985184, Length=380, Percent_Identity=28.6842105263158, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71982178, Length=268, Percent_Identity=30.5970149253731, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=31.8965517241379, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17534353, Length=366, Percent_Identity=26.2295081967213, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71985192, Length=311, Percent_Identity=27.9742765273312, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=26.0330578512397, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562446, Length=345, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=32.9815303430079, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI21356377, Length=360, Percent_Identity=33.6111111111111, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=32.4396782841823, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24660351, Length=368, Percent_Identity=33.9673913043478, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24646207, Length=359, Percent_Identity=32.033426183844, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281363737, Length=333, Percent_Identity=29.1291291291291, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI19920834, Length=402, Percent_Identity=24.8756218905473, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41428; Mature: 41428

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVGPWNTPERRELRATVRGFVEREVLPYLDDWEREGEIPRELHKKAGALGLLGIQFPES
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCHHHCCCCHHHHHHHCCCEEEEEEECCCC
AGGAGGDALDSVIVCEEMHQAGASGGLFASLFTCGIAVPHIIASGNTDLIERFAKPTLAG
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCCC
EKIGSLAITEPGGGSDVGHLTTTARRDGDHYIVNGAKTYITSGCRADFVVTAVRTGGPGS
CCCCCEEEECCCCCCCCCHHEEHHCCCCCEEEECCHHHHHCCCCCCCEEEEEEECCCCCC
AGISLLVVEKDTPGFTVSRKLDKMGWRASDTAELSYVDVRVPVENLVGQENSGSYQIAAA
CCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCEEEEEEEEECHHHHCCCCCCCCEEEHHH
FVSERVGLAVQAYAQAQRCLDLTLEWVRNRETFGRPLISRQAVQNTVTEMARRIDVARVY
HHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TREVARRSAEGETDLIAEVCFAKNTAVEAAEWVAHQAVQLFGGLGYMRESEVERQYRDIR
HHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEE
ILGIGGGTTEILTGLAAKRLGYQS
EEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNVGPWNTPERRELRATVRGFVEREVLPYLDDWEREGEIPRELHKKAGALGLLGIQFPES
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCHHHCCCCHHHHHHHCCCEEEEEEECCCC
AGGAGGDALDSVIVCEEMHQAGASGGLFASLFTCGIAVPHIIASGNTDLIERFAKPTLAG
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCCC
EKIGSLAITEPGGGSDVGHLTTTARRDGDHYIVNGAKTYITSGCRADFVVTAVRTGGPGS
CCCCCEEEECCCCCCCCCHHEEHHCCCCCEEEECCHHHHHCCCCCCCEEEEEEECCCCCC
AGISLLVVEKDTPGFTVSRKLDKMGWRASDTAELSYVDVRVPVENLVGQENSGSYQIAAA
CCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCEEEEEEEEECHHHHCCCCCCCCEEEHHH
FVSERVGLAVQAYAQAQRCLDLTLEWVRNRETFGRPLISRQAVQNTVTEMARRIDVARVY
HHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TREVARRSAEGETDLIAEVCFAKNTAVEAAEWVAHQAVQLFGGLGYMRESEVERQYRDIR
HHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEE
ILGIGGGTTEILTGLAAKRLGYQS
EEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]