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The map label for this gene is deoC

Identifier: 54027177

GI number: 54027177

Start: 5499193

End: 5499861

Strand: Reverse

Name: deoC

Synonym: nfa52030

Alternate gene names: 54027177

Gene position: 5499861-5499193 (Counterclockwise)

Preceding gene: 54027180

Following gene: 54027175

Centisome position: 91.34

GC content: 72.94

Gene sequence:

>669_bases
ATGGCAGAAACCGCGTTGCCGACCAGGGCCGAGGTGGCCGCTCGCATCGACCACACGCTGCTGGCGCCCGAGGCCACCGA
CGACGACGTCGCCGCGCTGGTGGCCGAGGCGCGCGACCTCGGCGTGTACGCCGTCTGCGTCTCGCCGTCGATGCTGCCGG
TGCGCGCGCCCGGACTGGTCGTGGCCACCGTCGCGGGATTCCCCTCGGGCAAACATCATTCGCTGGTCAAGGGGGCCGAG
GCGCGGCTGGCGGTGGACCAGGGCGCGGCCGAGGTCGACATGGTGATCGACGTGGGCGCCGCCCGCGCGGGCGAATACAG
CGCGGTGCTCGCCGACATCGTGACCGTGCGCGAGGCGATCTCGGATCGCGCGGTGCTCAAGGTGATCATCGAATCGGCGG
CGCTGTCGGACGAGGCGATCGTGGAGGTCTGCCGCGTCGCCGAACGCGCGGGCGCCGATTTCGTCAAGACCTCGACCGGT
TTTCATCCCGCGGGCGGGGCGAGCGTGCACGCGGTGCGGCTGATGGCCGAGACGGTGGGCGGCAGGCTCGGCATCAAGGC
CAGCGGTGGCATCCGCACCGCCGCGGCGGCCGCCGAACTGCTCGCGGCGGGCGCCACCCGGCTCGGGCTGTCCAAGTCGG
CGGCGGTGCTGGACGGTTTCCCCTCCTGA

Upstream 100 bases:

>100_bases
TGGCAACGCAATTCGGTGGTGTGCCGCGCTTCACGTGCGGTGTGCCGAGCTTCGCATACGGCGTGCCGGACCGCGCAGAC
GGTGTGCCAGACTGCGCAGC

Downstream 100 bases:

>100_bases
CCGCATCTGCTCAGCAGCGGACGTCGCTGCTGCCGGTGCTCTGGAGTTCGGTGCGGCCACCGGCCAGGTGCACGTCGATC
CCGTTGTCGGTGACCTCGAT

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MAETALPTRAEVAARIDHTLLAPEATDDDVAALVAEARDLGVYAVCVSPSMLPVRAPGLVVATVAGFPSGKHHSLVKGAE
ARLAVDQGAAEVDMVIDVGAARAGEYSAVLADIVTVREAISDRAVLKVIIESAALSDEAIVEVCRVAERAGADFVKTSTG
FHPAGGASVHAVRLMAETVGGRLGIKASGGIRTAAAAAELLAAGATRLGLSKSAAVLDGFPS

Sequences:

>Translated_222_residues
MAETALPTRAEVAARIDHTLLAPEATDDDVAALVAEARDLGVYAVCVSPSMLPVRAPGLVVATVAGFPSGKHHSLVKGAE
ARLAVDQGAAEVDMVIDVGAARAGEYSAVLADIVTVREAISDRAVLKVIIESAALSDEAIVEVCRVAERAGADFVKTSTG
FHPAGGASVHAVRLMAETVGGRLGIKASGGIRTAAAAAELLAAGATRLGLSKSAAVLDGFPS
>Mature_221_residues
AETALPTRAEVAARIDHTLLAPEATDDDVAALVAEARDLGVYAVCVSPSMLPVRAPGLVVATVAGFPSGKHHSLVKGAEA
RLAVDQGAAEVDMVIDVGAARAGEYSAVLADIVTVREAISDRAVLKVIIESAALSDEAIVEVCRVAERAGADFVKTSTGF
HPAGGASVHAVRLMAETVGGRLGIKASGGIRTAAAAAELLAAGATRLGLSKSAAVLDGFPS

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=198, Percent_Identity=31.3131313131313, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1790841, Length=205, Percent_Identity=35.1219512195122, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17533015, Length=223, Percent_Identity=28.2511210762332, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19922098, Length=158, Percent_Identity=29.746835443038, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_NOCFA (Q5YP36)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_121419.1
- ProteinModelPortal:   Q5YP36
- SMR:   Q5YP36
- GeneID:   3109815
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa52030
- NMPDR:   fig|247156.1.peg.4999
- HOGENOM:   HBG636421
- OMA:   CGFPSGK
- ProtClustDB:   PRK00507
- BioCyc:   NFAR247156:NFA52030-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 22343; Mature: 22212

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: ACT_SITE 156-156 ACT_SITE 186-186

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETALPTRAEVAARIDHTLLAPEATDDDVAALVAEARDLGVYAVCVSPSMLPVRAPGLV
CCCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCEECCCCEE
VATVAGFPSGKHHSLVKGAEARLAVDQGAAEVDMVIDVGAARAGEYSAVLADIVTVREAI
EEEEECCCCCCCCHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
SDRAVLKVIIESAALSDEAIVEVCRVAERAGADFVKTSTGFHPAGGASVHAVRLMAETVG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHC
GRLGIKASGGIRTAAAAAELLAAGATRLGLSKSAAVLDGFPS
CEEEEEECCCCHHHHHHHHHHHHCHHHHCCCCCHHHHCCCCC
>Mature Secondary Structure 
AETALPTRAEVAARIDHTLLAPEATDDDVAALVAEARDLGVYAVCVSPSMLPVRAPGLV
CCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCEECCCCEE
VATVAGFPSGKHHSLVKGAEARLAVDQGAAEVDMVIDVGAARAGEYSAVLADIVTVREAI
EEEEECCCCCCCCHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
SDRAVLKVIIESAALSDEAIVEVCRVAERAGADFVKTSTGFHPAGGASVHAVRLMAETVG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHC
GRLGIKASGGIRTAAAAAELLAAGATRLGLSKSAAVLDGFPS
CEEEEEECCCCHHHHHHHHHHHHCHHHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA