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The map label for this gene is yabD [H]

Identifier: 54026879

GI number: 54026879

Start: 5119768

End: 5120595

Strand: Reverse

Name: yabD [H]

Synonym: nfa49050

Alternate gene names: 54026879

Gene position: 5120595-5119768 (Counterclockwise)

Preceding gene: 54026881

Following gene: 54026878

Centisome position: 85.04

GC content: 72.34

Gene sequence:

>828_bases
GTGAGTGCCCGACGTCCGGCGCCGGACCTACCCGAGCCGCTCGCGCCGCTGGTCGACGCCCACACCCACCTGGACGCCTG
CGGCGCGACCGATGCCGCGTCGACGGCGGAGATCCTCGACCGCGCGGCCTCGGTCGGCGTCGGGCAGGTCGTGACCGTCG
CCGACGACCTCGCCGCCGCGCAGTGGGCGGTGCGGGCCGCGCACGCCGACCCGCGCGTGTTCGCCGCGGTCGCGCTGCAC
CCGACCCGGGCCGATGCGCTGGACACCGCCGCGCAGGCGGAACTGGAGCGGCTGGCGGCCGACCCGCGCACGGTGGCCGT
CGGCGAGACCGGCCTGGACTACTACTGGCCGGGCAAGCTGGAGGGCTGCGCCGACGTCGAGACCCAGATCGAGGCCTTCC
GCTGGCACATCGACCTGGCCAAACGGGTGCGCAAGCCGCTGATGATCCACAACCGGGAAGCCGACCACGACCTGCTCACC
GTGCTGCTGGACGAGGGCGCGCCGCCGACGGTGATCTTCCACTGCTTCTCCTCCGACACGAACATGGCGCTGTCGTGCGT
GGACGAGGGCTACATCCTGAGCTTCTCCGGAACGGTCAGCTTCAAGAACGCCCACGAGTTGCGGGAGGCGGCCACGGTGG
TGCCGGACGGTCAGATCCTGGTGGAGACCGACGCGCCGTACCTGACCCCGCACCCGTTCCGCGGCGCCCCCAACGAGCCG
TACTGCCTGCCCTACACCGTCCGTGCGCTGGCCGAGCTGCGCGGACAGGATCCGGTCGAGCTGGCGAAGATCACCACCGC
GAACGCGCGGCGGGTGTACGGCATCTGA

Upstream 100 bases:

>100_bases
CTGGTGCGTCCGCGCTCATGGTGCTGTCTACTGTAATGCTCGTGCCTGTGCTGTCCCATTCCACCGGCGCGTGTGCGATG
ACACGCGGAGGTGATCGTTC

Downstream 100 bases:

>100_bases
CGGGGATTGCGCGCGCGGTTGTTACCCGACCCCGCAGGTCGGAAAACGTAAGTGTGTCTCAGGTCACTTTTCGCCTCGAT
AGATGTCCTCTAGCAGGGCG

Product: putative DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSARRPAPDLPEPLAPLVDAHTHLDACGATDAASTAEILDRAASVGVGQVVTVADDLAAAQWAVRAAHADPRVFAAVALH
PTRADALDTAAQAELERLAADPRTVAVGETGLDYYWPGKLEGCADVETQIEAFRWHIDLAKRVRKPLMIHNREADHDLLT
VLLDEGAPPTVIFHCFSSDTNMALSCVDEGYILSFSGTVSFKNAHELREAATVVPDGQILVETDAPYLTPHPFRGAPNEP
YCLPYTVRALAELRGQDPVELAKITTANARRVYGI

Sequences:

>Translated_275_residues
MSARRPAPDLPEPLAPLVDAHTHLDACGATDAASTAEILDRAASVGVGQVVTVADDLAAAQWAVRAAHADPRVFAAVALH
PTRADALDTAAQAELERLAADPRTVAVGETGLDYYWPGKLEGCADVETQIEAFRWHIDLAKRVRKPLMIHNREADHDLLT
VLLDEGAPPTVIFHCFSSDTNMALSCVDEGYILSFSGTVSFKNAHELREAATVVPDGQILVETDAPYLTPHPFRGAPNEP
YCLPYTVRALAELRGQDPVELAKITTANARRVYGI
>Mature_274_residues
SARRPAPDLPEPLAPLVDAHTHLDACGATDAASTAEILDRAASVGVGQVVTVADDLAAAQWAVRAAHADPRVFAAVALHP
TRADALDTAAQAELERLAADPRTVAVGETGLDYYWPGKLEGCADVETQIEAFRWHIDLAKRVRKPLMIHNREADHDLLTV
LLDEGAPPTVIFHCFSSDTNMALSCVDEGYILSFSGTVSFKNAHELREAATVVPDGQILVETDAPYLTPHPFRGAPNEPY
CLPYTVRALAELRGQDPVELAKITTANARRVYGI

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=214, Percent_Identity=31.3084112149533, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI14042943, Length=266, Percent_Identity=23.6842105263158, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI110349734, Length=172, Percent_Identity=28.4883720930233, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI110349730, Length=172, Percent_Identity=29.0697674418605, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI226061853, Length=180, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI226061614, Length=174, Percent_Identity=28.1609195402299, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787342, Length=261, Percent_Identity=35.632183908046, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI48994985, Length=242, Percent_Identity=30.5785123966942, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI87082439, Length=270, Percent_Identity=29.2592592592593, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17559024, Length=268, Percent_Identity=28.7313432835821, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=25.0950570342205, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=193, Percent_Identity=33.6787564766839, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648690, Length=321, Percent_Identity=25.8566978193146, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24586117, Length=211, Percent_Identity=30.8056872037915, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221330018, Length=211, Percent_Identity=30.8056872037915, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 29618; Mature: 29486

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARRPAPDLPEPLAPLVDAHTHLDACGATDAASTAEILDRAASVGVGQVVTVADDLAAA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHH
QWAVRAAHADPRVFAAVALHPTRADALDTAAQAELERLAADPRTVAVGETGLDYYWPGKL
HHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCCC
EGCADVETQIEAFRWHIDLAKRVRKPLMIHNREADHDLLTVLLDEGAPPTVIFHCFSSDT
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHEEEEEECCCCCCEEEEEEECCCC
NMALSCVDEGYILSFSGTVSFKNAHELREAATVVPDGQILVETDAPYLTPHPFRGAPNEP
CEEEEEECCCEEEEEECEEEECHHHHHHHHHEECCCCEEEEECCCCCCCCCCCCCCCCCC
YCLPYTVRALAELRGQDPVELAKITTANARRVYGI
EECHHHHHHHHHHCCCCCHHHHEEECCCCEEECCC
>Mature Secondary Structure 
SARRPAPDLPEPLAPLVDAHTHLDACGATDAASTAEILDRAASVGVGQVVTVADDLAAA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHH
QWAVRAAHADPRVFAAVALHPTRADALDTAAQAELERLAADPRTVAVGETGLDYYWPGKL
HHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCCC
EGCADVETQIEAFRWHIDLAKRVRKPLMIHNREADHDLLTVLLDEGAPPTVIFHCFSSDT
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHEEEEEECCCCCCEEEEEEECCCC
NMALSCVDEGYILSFSGTVSFKNAHELREAATVVPDGQILVETDAPYLTPHPFRGAPNEP
CEEEEEECCCEEEEEECEEEECHHHHHHHHHEECCCCEEEEECCCCCCCCCCCCCCCCCC
YCLPYTVRALAELRGQDPVELAKITTANARRVYGI
EECHHHHHHHHHHCCCCCHHHHEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]