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The map label for this gene is rfbD [H]

Identifier: 54026611

GI number: 54026611

Start: 4827409

End: 4828266

Strand: Reverse

Name: rfbD [H]

Synonym: nfa46380

Alternate gene names: 54026611

Gene position: 4828266-4827409 (Counterclockwise)

Preceding gene: 54026615

Following gene: 54026610

Centisome position: 80.19

GC content: 75.64

Gene sequence:

>858_bases
GTGACCGACGCCGTACCGCACCGTTCGCCCGCCCGTCTCGTCGTCACCGGCGCGGCCGGGCAGGTCGGCCGCCACCTGAT
GCGCCTGGCCCCGCACGCGCGCGGATACGACCGCGCGCACCTCGACATCACCGACGCCGACGCCGTCCGCGCCGTCGTCC
ACCCGGGGGATGTGGTGATCAACTGCGCCGCCTACACCGCCGTCGACAAGGCCGAGACCGAACCCGACGCCGCCTTCGCC
GTCAACGGGACCGGTCCGGCCGTGCTGGCGTCGGCCTGCGCACGCGCGGGCGCCCGACTCATCCATCTGTCCACCGACTA
CGTCTTCGGGGGTACCCACACCGACCCGTACGAACCCACGGATCCGACCGCCCCGGCCTCGGCGTACGGGCGCTCCAAGC
TGGCGGGGGAGCGGGCGGTGCTCGACCTGGCCCCCGCCGCGCACGTGGTGCGCACCGCCTGGGTCTACACCGGCGACCGG
GGCGATTTCGTCGCCACCATGCGCCGCTTCGCCGCCGAACGCCCCACCGTCGACGTGGTCGACGACCAGATCGGATCGCC
CACCTACGCCGCCGACCTGGCCGCGGGCCTGCTCGAACTCGCCGCCACCCCGGCGGCGCCGCCGCTGCTGCACGCCACCA
ACGCCGGGACGGCGAGCTGGTTCGAGCTGGCGCGGGCGGTGTTCGCCGAGATCGGCGCCGATCCCGAGCGGGTGCGGCCG
TGCGCGTCCTCGGCCTTCCCGCGGCCCGCGCCGCGGCCGGCCTACTCGGTGCTGTCGAACCGGGCCTGGGTCGCGGCCGG
TCTGACCCCGCTGCGACCCTGGCGGGCGGCACTGCACGAGGCGTTGGGCAACCGCTGA

Upstream 100 bases:

>100_bases
TCCCTTCCCCGCCCCGGGGCGGATTCGTGGCTCCAGGCTAACCAACGGCTACCGTCATCGACCGCACCCGCACGTGTACC
GGCGTGCCAGACTTGCGGCC

Downstream 100 bases:

>100_bases
ACCGACACCTACGCTGGGCTGTCGTGAGCGTTTCCGATTCCGCCGCCTCCGGTGGCCTGGCCGTGGTCACGGTGACCTAT
TCACCGGGGGAGCACCTCGA

Product: putative dTDP-4-dehydrorhamnose reductase

Products: NA

Alternate protein names: dTDP-4-keto-L-rhamnose reductase; dTDP-6-deoxy-L-lyxo-4-hexulose reductase; dTDP-6-deoxy-L-mannose dehydrogenase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTDAVPHRSPARLVVTGAAGQVGRHLMRLAPHARGYDRAHLDITDADAVRAVVHPGDVVINCAAYTAVDKAETEPDAAFA
VNGTGPAVLASACARAGARLIHLSTDYVFGGTHTDPYEPTDPTAPASAYGRSKLAGERAVLDLAPAAHVVRTAWVYTGDR
GDFVATMRRFAAERPTVDVVDDQIGSPTYAADLAAGLLELAATPAAPPLLHATNAGTASWFELARAVFAEIGADPERVRP
CASSAFPRPAPRPAYSVLSNRAWVAAGLTPLRPWRAALHEALGNR

Sequences:

>Translated_285_residues
MTDAVPHRSPARLVVTGAAGQVGRHLMRLAPHARGYDRAHLDITDADAVRAVVHPGDVVINCAAYTAVDKAETEPDAAFA
VNGTGPAVLASACARAGARLIHLSTDYVFGGTHTDPYEPTDPTAPASAYGRSKLAGERAVLDLAPAAHVVRTAWVYTGDR
GDFVATMRRFAAERPTVDVVDDQIGSPTYAADLAAGLLELAATPAAPPLLHATNAGTASWFELARAVFAEIGADPERVRP
CASSAFPRPAPRPAYSVLSNRAWVAAGLTPLRPWRAALHEALGNR
>Mature_284_residues
TDAVPHRSPARLVVTGAAGQVGRHLMRLAPHARGYDRAHLDITDADAVRAVVHPGDVVINCAAYTAVDKAETEPDAAFAV
NGTGPAVLASACARAGARLIHLSTDYVFGGTHTDPYEPTDPTAPASAYGRSKLAGERAVLDLAPAAHVVRTAWVYTGDRG
DFVATMRRFAAERPTVDVVDDQIGSPTYAADLAAGLLELAATPAAPPLLHATNAGTASWFELARAVFAEIGADPERVRPC
ASSAFPRPAPRPAYSVLSNRAWVAAGLTPLRPWRAALHEALGNR

Specific function: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose. Involved in the biosynthesis of the dTDP-L-rhamnose which is a component of the critical linker, D-N-acetylglucosamine-L-rhamnose disaccharide, which connects the galacta

COG id: COG1091

COG function: function code M; dTDP-4-dehydrorhamnose reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose reductase family [H]

Homologues:

Organism=Homo sapiens, GI33519455, Length=299, Percent_Identity=28.0936454849498, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI11034825, Length=299, Percent_Identity=28.0936454849498, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1788352, Length=292, Percent_Identity=35.958904109589, Blast_Score=155, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005913
- InterPro:   IPR016040 [H]

Pfam domain/function: PF04321 RmlD_sub_bind [H]

EC number: =1.1.1.133 [H]

Molecular weight: Translated: 29889; Mature: 29758

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAVPHRSPARLVVTGAAGQVGRHLMRLAPHARGYDRAHLDITDADAVRAVVHPGDVVI
CCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHEEECCCCEEE
NCAAYTAVDKAETEPDAAFAVNGTGPAVLASACARAGARLIHLSTDYVFGGTHTDPYEPT
EEHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCEEEEEECCEEECCCCCCCCCCC
DPTAPASAYGRSKLAGERAVLDLAPAAHVVRTAWVYTGDRGDFVATMRRFAAERPTVDVV
CCCCCHHHHCHHHHCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCCEEEH
DDQIGSPTYAADLAAGLLELAATPAAPPLLHATNAGTASWFELARAVFAEIGADPERVRP
HHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCHHHHCH
CASSAFPRPAPRPAYSVLSNRAWVAAGLTPLRPWRAALHEALGNR
HHHCCCCCCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDAVPHRSPARLVVTGAAGQVGRHLMRLAPHARGYDRAHLDITDADAVRAVVHPGDVVI
CCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHEEECCCCEEE
NCAAYTAVDKAETEPDAAFAVNGTGPAVLASACARAGARLIHLSTDYVFGGTHTDPYEPT
EEHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCEEEEEECCEEECCCCCCCCCCC
DPTAPASAYGRSKLAGERAVLDLAPAAHVVRTAWVYTGDRGDFVATMRRFAAERPTVDVV
CCCCCHHHHCHHHHCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCCEEEH
DDQIGSPTYAADLAAGLLELAATPAAPPLLHATNAGTASWFELARAVFAEIGADPERVRP
HHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCHHHHCH
CASSAFPRPAPRPAYSVLSNRAWVAAGLTPLRPWRAALHEALGNR
HHHCCCCCCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA