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The map label for this gene is cmcT [H]

Identifier: 54026604

GI number: 54026604

Start: 4819164

End: 4820591

Strand: Reverse

Name: cmcT [H]

Synonym: nfa46310

Alternate gene names: 54026604

Gene position: 4820591-4819164 (Counterclockwise)

Preceding gene: 54026605

Following gene: 54026603

Centisome position: 80.06

GC content: 71.99

Gene sequence:

>1428_bases
ATGAGTACGCAGGTACACACCACCACCACCACCACTCGGAAGTGGTGGGCTCTCGCGGTGATCGCCACCGCCCAGTTCAT
GGTCATCATGGACACCTCGATCATCGGGATCGCGCTGCCCCGCATGCAGGCCGATCTCGGCTTCTCGCAGGAGAACCTGA
CCTGGGTGTTCAACGCCTACGTCATCGCCTTCGGCGGCCTGCTGCTGCTCGGCGGCAGGCTCTCGGACCTCTTCGGCGCC
CGCCGTGTGTTCGCCGCGGGCTGGGTGGTGCTGCTGGTCGGTTCGGTGCTGGCCGGCGCGGCGGGCACGGTCGCCGTCGA
ACTGGCGGGCCGGGCGATCCAGGGCGCGGGCGCGGCCATGATCGCACCGTCGGCGCTGACCCTGCTGATGATGCTGTTCG
GATCCTCGCCGCAGGAACTGACCAAGGCGCTGGCGATCTACGGCGCCGCGGCACCCGCGGGCGGCACCGCGGGCGTGTTC
CTCGGCGGTGTCATCACCGAATACATCAGCTGGCCCTGGGTGTTCTACATCAACATCCCGATCGCCGTGCTGGCGTTGCT
CGCGGCACCCGCGCTGATGCCCGCCGCCCCGGCCCGCTCCGGCTCGCTCGACCTGCTCGGCGCCGTCACCGCCACCGCGG
GCCTGGCCGCCGCCGTCTACGGCATCGTCCGCGCGCCCGAGGTGGGTTGGGCGTCGGGGCAGACCTGGGGCGTGCTCGCG
GTGGCCGCCGCGCTGCTCGCCGGGTTCGTGGCACTGCAGTCGCGCCGCACCGAACCGCTGATGCCGCTGCGCATCTTCCG
CGCACCCGACCTCGCCGCCGCCAACCTCGCCCAGCTGCTGCTCGGCGCCGCATGGGTGCCGATGTGGTTCTTCCTGAACC
TGTACCTGCAGCAGGTGCTCGGCTACAGCGCCTTCCCCTCGGGCGCGGCGCTGCTGCCGATGACCACCCTGATCATGCTC
GGCATGATCGTGCTCGCACCGCGGGCGATGCAGCGGTTCGGCGCGAAGCCGATGATCGTGACCGGCCTGGCGGTGCTCGG
ACTCGGCCTGGGCATCATGTCGCTGATCCGCCCGACCGGCACCTTCTGGATCGACGTCCTGCCCGCCTCGCTCGTTGCCG
CCGGTGGCATGTCGCTGGCCTTCATCCCCTCGCTCGGCACCGCCATCGGCGCGGCCCGGCCGGAGGAGGGCGGCCTGGCC
TCGGGCCTGGTCAACGTCAGCTACCAGATCGGCTCGGCGCTCGGGCTGGCCGCGATGACCGCCGTGGCCACGGCGTTCGG
CGCCGACCGGCTCGGTGACCTGCCCCGGCTGACCGACGGCTTCTCCGCGGCCTTCCTCGGTGCCGCCGCCATCGCCCTGG
TCGGCGCGGCAGTGGCCGCGGCCACCCTGTCCAGCCCCGCGAAAGCCGCCGCGCCACAACCCGAATGA

Upstream 100 bases:

>100_bases
CCTCGCCACCCCGCGCTGACCCGGTAACCGGAAACCACCGGGCCGACCGCTGCATAGGCAAATACCCTACCGGGGTTAGG
TAAACAGGACGGACATTGTC

Downstream 100 bases:

>100_bases
GCCGGACTCGGGCGGGCAGCCCACCAGGATGCCCGTCCGAGCCGCCCACCCCGCGCCGGTCGAGGAGCAATCATGTTCGC
CGCACTGTTCACCCACCGCG

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSTQVHTTTTTTRKWWALAVIATAQFMVIMDTSIIGIALPRMQADLGFSQENLTWVFNAYVIAFGGLLLLGGRLSDLFGA
RRVFAAGWVVLLVGSVLAGAAGTVAVELAGRAIQGAGAAMIAPSALTLLMMLFGSSPQELTKALAIYGAAAPAGGTAGVF
LGGVITEYISWPWVFYINIPIAVLALLAAPALMPAAPARSGSLDLLGAVTATAGLAAAVYGIVRAPEVGWASGQTWGVLA
VAAALLAGFVALQSRRTEPLMPLRIFRAPDLAAANLAQLLLGAAWVPMWFFLNLYLQQVLGYSAFPSGAALLPMTTLIML
GMIVLAPRAMQRFGAKPMIVTGLAVLGLGLGIMSLIRPTGTFWIDVLPASLVAAGGMSLAFIPSLGTAIGAARPEEGGLA
SGLVNVSYQIGSALGLAAMTAVATAFGADRLGDLPRLTDGFSAAFLGAAAIALVGAAVAAATLSSPAKAAAPQPE

Sequences:

>Translated_475_residues
MSTQVHTTTTTTRKWWALAVIATAQFMVIMDTSIIGIALPRMQADLGFSQENLTWVFNAYVIAFGGLLLLGGRLSDLFGA
RRVFAAGWVVLLVGSVLAGAAGTVAVELAGRAIQGAGAAMIAPSALTLLMMLFGSSPQELTKALAIYGAAAPAGGTAGVF
LGGVITEYISWPWVFYINIPIAVLALLAAPALMPAAPARSGSLDLLGAVTATAGLAAAVYGIVRAPEVGWASGQTWGVLA
VAAALLAGFVALQSRRTEPLMPLRIFRAPDLAAANLAQLLLGAAWVPMWFFLNLYLQQVLGYSAFPSGAALLPMTTLIML
GMIVLAPRAMQRFGAKPMIVTGLAVLGLGLGIMSLIRPTGTFWIDVLPASLVAAGGMSLAFIPSLGTAIGAARPEEGGLA
SGLVNVSYQIGSALGLAAMTAVATAFGADRLGDLPRLTDGFSAAFLGAAAIALVGAAVAAATLSSPAKAAAPQPE
>Mature_474_residues
STQVHTTTTTTRKWWALAVIATAQFMVIMDTSIIGIALPRMQADLGFSQENLTWVFNAYVIAFGGLLLLGGRLSDLFGAR
RVFAAGWVVLLVGSVLAGAAGTVAVELAGRAIQGAGAAMIAPSALTLLMMLFGSSPQELTKALAIYGAAAPAGGTAGVFL
GGVITEYISWPWVFYINIPIAVLALLAAPALMPAAPARSGSLDLLGAVTATAGLAAAVYGIVRAPEVGWASGQTWGVLAV
AAALLAGFVALQSRRTEPLMPLRIFRAPDLAAANLAQLLLGAAWVPMWFFLNLYLQQVLGYSAFPSGAALLPMTTLIMLG
MIVLAPRAMQRFGAKPMIVTGLAVLGLGLGIMSLIRPTGTFWIDVLPASLVAAGGMSLAFIPSLGTAIGAARPEEGGLAS
GLVNVSYQIGSALGLAAMTAVATAFGADRLGDLPRLTDGFSAAFLGAAAIALVGAAVAAATLSSPAKAAAPQPE

Specific function: Involved in cephamycin export [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=427, Percent_Identity=27.4004683840749, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1790195, Length=412, Percent_Identity=27.9126213592233, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788392, Length=407, Percent_Identity=28.5012285012285, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788710, Length=307, Percent_Identity=24.4299674267101, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1789042, Length=301, Percent_Identity=25.9136212624585, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324954, Length=384, Percent_Identity=26.8229166666667, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323520, Length=397, Percent_Identity=24.9370277078086, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6323935, Length=386, Percent_Identity=25.6476683937824, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322958, Length=396, Percent_Identity=21.2121212121212, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325455, Length=139, Percent_Identity=28.7769784172662, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48332; Mature: 48201

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQVHTTTTTTRKWWALAVIATAQFMVIMDTSIIGIALPRMQADLGFSQENLTWVFNAY
CCCEEEECCCCCHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VIAFGGLLLLGGRLSDLFGARRVFAAGWVVLLVGSVLAGAAGTVAVELAGRAIQGAGAAM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHCCCCCHH
IAPSALTLLMMLFGSSPQELTKALAIYGAAAPAGGTAGVFLGGVITEYISWPWVFYINIP
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECH
IAVLALLAAPALMPAAPARSGSLDLLGAVTATAGLAAAVYGIVRAPEVGWASGQTWGVLA
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VAAALLAGFVALQSRRTEPLMPLRIFRAPDLAAANLAQLLLGAAWVPMWFFLNLYLQQVL
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYSAFPSGAALLPMTTLIMLGMIVLAPRAMQRFGAKPMIVTGLAVLGLGLGIMSLIRPTG
CCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
TFWIDVLPASLVAAGGMSLAFIPSLGTAIGAARPEEGGLASGLVNVSYQIGSALGLAAMT
CHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVATAFGADRLGDLPRLTDGFSAAFLGAAAIALVGAAVAAATLSSPAKAAAPQPE
HHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
STQVHTTTTTTRKWWALAVIATAQFMVIMDTSIIGIALPRMQADLGFSQENLTWVFNAY
CCEEEECCCCCHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VIAFGGLLLLGGRLSDLFGARRVFAAGWVVLLVGSVLAGAAGTVAVELAGRAIQGAGAAM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHCCCCCHH
IAPSALTLLMMLFGSSPQELTKALAIYGAAAPAGGTAGVFLGGVITEYISWPWVFYINIP
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECH
IAVLALLAAPALMPAAPARSGSLDLLGAVTATAGLAAAVYGIVRAPEVGWASGQTWGVLA
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VAAALLAGFVALQSRRTEPLMPLRIFRAPDLAAANLAQLLLGAAWVPMWFFLNLYLQQVL
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYSAFPSGAALLPMTTLIMLGMIVLAPRAMQRFGAKPMIVTGLAVLGLGLGIMSLIRPTG
CCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
TFWIDVLPASLVAAGGMSLAFIPSLGTAIGAARPEEGGLASGLVNVSYQIGSALGLAAMT
CHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVATAFGADRLGDLPRLTDGFSAAFLGAAAIALVGAAVAAATLSSPAKAAAPQPE
HHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8440253 [H]