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The map label for this gene is moeB [H]

Identifier: 54026540

GI number: 54026540

Start: 4749762

End: 4750946

Strand: Reverse

Name: moeB [H]

Synonym: nfa45670

Alternate gene names: 54026540

Gene position: 4750946-4749762 (Counterclockwise)

Preceding gene: 54026541

Following gene: 54026539

Centisome position: 78.9

GC content: 67.76

Gene sequence:

>1185_bases
GTGTCATCATCGAAGTCCCTGCCGCCACTGGTCGAGCCGGCCGCGGAACTGAGCAAGGACGAGATCGCCCGCTACAGCCG
TCACCTGATCATCCCGGACGTCGGGGTGGACGGGCAGAAGCGTTTGAAGAACGCGAAGGTGCTGGTGATCGGCGCAGGCG
GGCTGGGTTCGCCCGCGCTGCTGTACCTGGCCGCCGCGGGTGTCGGCACGCTGGGCATCGTGGAGTTCGACGAGGTCGAT
TCCTCCAACCTGCAGCGCCAGATCATCCACGGTGAGTCCGACATCGGCCGTCCCAAGGCCGACAGCGCGCGCGATTCCAT
CCTGGAGATCAACTCCGGCGTCGACGTGCGGCTGCACAAGATCCGGCTGGAGCCGGAGAACGCCGTCGAACTGTTCGGTG
AGTACGACCTGATCCTGGACGGCACCGACAACTTCGCCACCCGCTACCTGGTCAACGACGCCGCCGTGCTGGCGGGCAAG
CCCTACGTGTGGGGCTCGATCTACCGGTTCGAGGGCCAGGTCTCGGTGTTCTGGGAGGACGCGCCGGACGGGCGCGGCAT
CAACTACCGCGACCTGTACCCGGAGGCCCCGCCGCCCGGCATGGTGCCCTCCTGCGCCGAGGGCGGCGTGCTCGGCGTGC
TGTGCGCGTCCATCGGTTCGATCATGGTGACCGAGGCGATCAAGCTGATCACCGGCATCGGCGACCCGCTGCTGGGCCGG
CTGATGGTCTACGACGCACTGGACATGACCTACCGCACCATCAAGCTGCGCCGCGACCCGGACCGGCAGCCGATCACCGA
GTTGATCGACTACGAGGCGTTCTGCGGCGTGGTGTCGGAGGAGGGCCAGGCCGCCGCGGCCGGCTCGACCATCACCGCCC
GCGAGCTCAAGGAGCTGCTGGACGCGGGCAAGGAGATCGAGCTGATCGACGTGCGCGAGCCGGTGGAGTGGGACATCGTG
CACATCGAGGGCGCGAAGCTGATCCCCAAGGACCGCATCCTGTCCGGGGAGGCGCTGTCCGAACTGCCGCAGAACCGGCC
GATCGTGCTGCACTGCAAGACCGGCATCCGGTCCGCGGAGGCATTGGCGGTGCTCAAGAACGCCGGCTTCACCGACGCCA
CGCACGTGCAGGGCGGAATCGTGGCCTGGGCCAACCAGATCGACCCGTCGCTGCCGGTTTACTGA

Upstream 100 bases:

>100_bases
CTGACCTCACCCGGGGTGCGCGACCATACTGGGGAAGAACGGCGCGCGTCTCGACGTTGCACATCGGGATTCGGCCAATT
CGATTCGAGGAGTCCTGGAC

Downstream 100 bases:

>100_bases
GTCGCCCGGCACGGCCCCGTACCTCGGCCGATCGCGGACGCTGCGTCTCGGCGCGGCGCCCGAATCGGGCACCGGAGCGG
CGTTACCGTACCGGTTGTGA

Product: molybdopterin biosynthesis-like protein MoeZ

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSSSKSLPPLVEPAAELSKDEIARYSRHLIIPDVGVDGQKRLKNAKVLVIGAGGLGSPALLYLAAAGVGTLGIVEFDEVD
SSNLQRQIIHGESDIGRPKADSARDSILEINSGVDVRLHKIRLEPENAVELFGEYDLILDGTDNFATRYLVNDAAVLAGK
PYVWGSIYRFEGQVSVFWEDAPDGRGINYRDLYPEAPPPGMVPSCAEGGVLGVLCASIGSIMVTEAIKLITGIGDPLLGR
LMVYDALDMTYRTIKLRRDPDRQPITELIDYEAFCGVVSEEGQAAAAGSTITARELKELLDAGKEIELIDVREPVEWDIV
HIEGAKLIPKDRILSGEALSELPQNRPIVLHCKTGIRSAEALAVLKNAGFTDATHVQGGIVAWANQIDPSLPVY

Sequences:

>Translated_394_residues
MSSSKSLPPLVEPAAELSKDEIARYSRHLIIPDVGVDGQKRLKNAKVLVIGAGGLGSPALLYLAAAGVGTLGIVEFDEVD
SSNLQRQIIHGESDIGRPKADSARDSILEINSGVDVRLHKIRLEPENAVELFGEYDLILDGTDNFATRYLVNDAAVLAGK
PYVWGSIYRFEGQVSVFWEDAPDGRGINYRDLYPEAPPPGMVPSCAEGGVLGVLCASIGSIMVTEAIKLITGIGDPLLGR
LMVYDALDMTYRTIKLRRDPDRQPITELIDYEAFCGVVSEEGQAAAAGSTITARELKELLDAGKEIELIDVREPVEWDIV
HIEGAKLIPKDRILSGEALSELPQNRPIVLHCKTGIRSAEALAVLKNAGFTDATHVQGGIVAWANQIDPSLPVY
>Mature_393_residues
SSSKSLPPLVEPAAELSKDEIARYSRHLIIPDVGVDGQKRLKNAKVLVIGAGGLGSPALLYLAAAGVGTLGIVEFDEVDS
SNLQRQIIHGESDIGRPKADSARDSILEINSGVDVRLHKIRLEPENAVELFGEYDLILDGTDNFATRYLVNDAAVLAGKP
YVWGSIYRFEGQVSVFWEDAPDGRGINYRDLYPEAPPPGMVPSCAEGGVLGVLCASIGSIMVTEAIKLITGIGDPLLGRL
MVYDALDMTYRTIKLRRDPDRQPITELIDYEAFCGVVSEEGQAAAAGSTITARELKELLDAGKEIELIDVREPVEWDIVH
IEGAKLIPKDRILSGEALSELPQNRPIVLHCKTGIRSAEALAVLKNAGFTDATHVQGGIVAWANQIDPSLPVY

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=414, Percent_Identity=40.5797101449275, Blast_Score=253, Evalue=1e-67,
Organism=Homo sapiens, GI4885649, Length=132, Percent_Identity=32.5757575757576, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI38045944, Length=114, Percent_Identity=35.0877192982456, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI38045942, Length=114, Percent_Identity=35.0877192982456, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787048, Length=248, Percent_Identity=40.7258064516129, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87082356, Length=245, Percent_Identity=37.5510204081633, Blast_Score=152, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17540406, Length=411, Percent_Identity=37.956204379562, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71984476, Length=118, Percent_Identity=36.4406779661017, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193203301, Length=141, Percent_Identity=30.4964539007092, Blast_Score=78, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6321903, Length=408, Percent_Identity=37.5, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6320598, Length=143, Percent_Identity=30.0699300699301, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325438, Length=124, Percent_Identity=30.6451612903226, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322639, Length=222, Percent_Identity=25.2252252252252, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582879, Length=403, Percent_Identity=41.1910669975186, Blast_Score=294, Evalue=9e-80,
Organism=Drosophila melanogaster, GI24660640, Length=139, Percent_Identity=33.8129496402878, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573937, Length=192, Percent_Identity=25, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42530; Mature: 42399

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSKSLPPLVEPAAELSKDEIARYSRHLIIPDVGVDGQKRLKNAKVLVIGAGGLGSPAL
CCCCCCCCCHHCHHHHCCHHHHHHHHCEEEECCCCCCHHHHHCCCEEEEEECCCCCCHHH
LYLAAAGVGTLGIVEFDEVDSSNLQRQIIHGESDIGRPKADSARDSILEINSGVDVRLHK
HHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCHHHCEEEECCCCEEEEEE
IRLEPENAVELFGEYDLILDGTDNFATRYLVNDAAVLAGKPYVWGSIYRFEGQVSVFWED
EEECCHHHHHHCCCEEEEEECCCCCEEEEEECCCCEECCCCCEEEEEEEECCEEEEEEEC
APDGRGINYRDLYPEAPPPGMVPSCAEGGVLGVLCASIGSIMVTEAIKLITGIGDPLLGR
CCCCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LMVYDALDMTYRTIKLRRDPDRQPITELIDYEAFCGVVSEEGQAAAAGSTITARELKELL
HHHHHHHHCEEEEEEEECCCCCCHHHHHHCHHHHHCCCCCCCCEECCCCCCCHHHHHHHH
DAGKEIELIDVREPVEWDIVHIEGAKLIPKDRILSGEALSELPQNRPIVLHCKTGIRSAE
HCCCCEEEEECCCCCEEEEEEECCCEECCHHHCCCCHHHHHCCCCCCEEEEECCCCCCHH
ALAVLKNAGFTDATHVQGGIVAWANQIDPSLPVY
HHHHHHCCCCCCCHHCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
SSSKSLPPLVEPAAELSKDEIARYSRHLIIPDVGVDGQKRLKNAKVLVIGAGGLGSPAL
CCCCCCCCHHCHHHHCCHHHHHHHHCEEEECCCCCCHHHHHCCCEEEEEECCCCCCHHH
LYLAAAGVGTLGIVEFDEVDSSNLQRQIIHGESDIGRPKADSARDSILEINSGVDVRLHK
HHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCHHHCEEEECCCCEEEEEE
IRLEPENAVELFGEYDLILDGTDNFATRYLVNDAAVLAGKPYVWGSIYRFEGQVSVFWED
EEECCHHHHHHCCCEEEEEECCCCCEEEEEECCCCEECCCCCEEEEEEEECCEEEEEEEC
APDGRGINYRDLYPEAPPPGMVPSCAEGGVLGVLCASIGSIMVTEAIKLITGIGDPLLGR
CCCCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LMVYDALDMTYRTIKLRRDPDRQPITELIDYEAFCGVVSEEGQAAAAGSTITARELKELL
HHHHHHHHCEEEEEEEECCCCCCHHHHHHCHHHHHCCCCCCCCEECCCCCCCHHHHHHHH
DAGKEIELIDVREPVEWDIVHIEGAKLIPKDRILSGEALSELPQNRPIVLHCKTGIRSAE
HCCCCEEEEECCCCCEEEEEEECCCEECCHHHCCCCHHHHHCCCCCCEEEEECCCCCCHH
ALAVLKNAGFTDATHVQGGIVAWANQIDPSLPVY
HHHHHHCCCCCCCHHCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]