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The map label for this gene is yjiA [C]

Identifier: 54026291

GI number: 54026291

Start: 4477398

End: 4478540

Strand: Reverse

Name: yjiA [C]

Synonym: nfa43200

Alternate gene names: 54026291

Gene position: 4478540-4477398 (Counterclockwise)

Preceding gene: 54026292

Following gene: 54026287

Centisome position: 74.38

GC content: 72.27

Gene sequence:

>1143_bases
GTGTCGCACGGCGGCCTCCTGGTCGCCGGCCTCGGCCGGTGCGGCGCGGGCGGCGCCCGCGACCGCTGGCTCACACCTGC
CGCGGGCGGCCCGGTGGCGGCGCCTAGGGTGGTCGGGGTGAGCGAGCGGATTCCTGTGCTGATCGTGGCCGGCTTTCTCG
GCGCCGGGAAGACCACCATGCTCAACCACCTGCTGCGTGACGACAGCGGCACGCGGATCGGTGTGGTGGTCAACGACTTC
GGCGCCGTCAACATCGACGCGATGCTGGTCGCCGGGCAGGTCGACGCGATGGTCTCGCTCGGCAACGGCTGTGTGTGCTG
CGCGATCGACGTGAGCGAACTGGACGAGATGTTCGAGCGGCTGACCCAGCCGCAGGCCGGCATCGACGTCATCGTGGTGG
AAGCCAGCGGCCTGGCCGAGCCGGGCAATCTGATCCGGATGGTGCTGGGCAGCGAGAACCCGCGCATCCGCTACGGCGGG
CTGATCGAGGTGGTCGACGCCGAGCAGTTCCCGGACAGCCGGGCCCGCCACCCCGAGCTGGCCGGTCACCTGCGCATGGC
CGATCTGGTGGTGCTCAACAAGGCCGATCGGGTCGAGCCCGGCGTGCTCGACCGGCTGCGGGCCGAGATCGCCGAGCACG
CCCGCGGTGTCCCGGTGTACGCGACCGCGCACGGCCGCATCGATCCGGCCCTGCTGTTCGACCCGCCCGCGCGTGAGCGC
ACACCGGTGGCCGAGCAGCTCAGCTTCGACGAGTTGTGGCGCGAGCACGACCACGGCGACCCCGGGCACCGGCATCTGCA
CGACGACTACACCAGCGTGTCGTTCACCAGCGACCGAGATCTGCACCCGCGCAGGCTGATCGGCGTCCTGGAGGATCCGC
CGCCCGGGCTGTTCCGCGCCAAGGGCGTGCTCGCGTTCGCCGGTGACCACCGCAAGTTCACCCTGCACGTGGTGGGCAGG
CACATCCGCCTCGAGCCGCAGTCCTGGCGGCGCGACGAGGCACGCGCGAGCTCCCTCGTGCTCATCGGCGCGGGCCTGCC
CGCGGACACGGCGCTGGCGCGGTTGCGCGACACCGTGCACGCCGAGCCCGAGCCGCCGGACGAGCAGGCCATGCTCGGCG
TGTGGCGGTACGTGCCGCACTGA

Upstream 100 bases:

>100_bases
ACGCCGACCGTCTCCACCTCCGGCGGATCCCGCCGCGGTGACCCGGACCGGCGAGCACCGGGTTCCACGGACCCGAATCC
TGGGGTTCTCGGCGGCGAGG

Downstream 100 bases:

>100_bases
CCGCTCAGGTGCAGGCGTTCACCCATTCGGAGAGGCCGTCGGCGAAGAGTTGACGCTTCCAGATCGGCACCTCGTGCTTG
ATCCGGTCGACCAGTTCGGC

Product: putative cobalamin synthesis protein

Products: NA

Alternate protein names: P47K [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSHGGLLVAGLGRCGAGGARDRWLTPAAGGPVAAPRVVGVSERIPVLIVAGFLGAGKTTMLNHLLRDDSGTRIGVVVNDF
GAVNIDAMLVAGQVDAMVSLGNGCVCCAIDVSELDEMFERLTQPQAGIDVIVVEASGLAEPGNLIRMVLGSENPRIRYGG
LIEVVDAEQFPDSRARHPELAGHLRMADLVVLNKADRVEPGVLDRLRAEIAEHARGVPVYATAHGRIDPALLFDPPARER
TPVAEQLSFDELWREHDHGDPGHRHLHDDYTSVSFTSDRDLHPRRLIGVLEDPPPGLFRAKGVLAFAGDHRKFTLHVVGR
HIRLEPQSWRRDEARASSLVLIGAGLPADTALARLRDTVHAEPEPPDEQAMLGVWRYVPH

Sequences:

>Translated_380_residues
MSHGGLLVAGLGRCGAGGARDRWLTPAAGGPVAAPRVVGVSERIPVLIVAGFLGAGKTTMLNHLLRDDSGTRIGVVVNDF
GAVNIDAMLVAGQVDAMVSLGNGCVCCAIDVSELDEMFERLTQPQAGIDVIVVEASGLAEPGNLIRMVLGSENPRIRYGG
LIEVVDAEQFPDSRARHPELAGHLRMADLVVLNKADRVEPGVLDRLRAEIAEHARGVPVYATAHGRIDPALLFDPPARER
TPVAEQLSFDELWREHDHGDPGHRHLHDDYTSVSFTSDRDLHPRRLIGVLEDPPPGLFRAKGVLAFAGDHRKFTLHVVGR
HIRLEPQSWRRDEARASSLVLIGAGLPADTALARLRDTVHAEPEPPDEQAMLGVWRYVPH
>Mature_379_residues
SHGGLLVAGLGRCGAGGARDRWLTPAAGGPVAAPRVVGVSERIPVLIVAGFLGAGKTTMLNHLLRDDSGTRIGVVVNDFG
AVNIDAMLVAGQVDAMVSLGNGCVCCAIDVSELDEMFERLTQPQAGIDVIVVEASGLAEPGNLIRMVLGSENPRIRYGGL
IEVVDAEQFPDSRARHPELAGHLRMADLVVLNKADRVEPGVLDRLRAEIAEHARGVPVYATAHGRIDPALLFDPPARERT
PVAEQLSFDELWREHDHGDPGHRHLHDDYTSVSFTSDRDLHPRRLIGVLEDPPPGLFRAKGVLAFAGDHRKFTLHVVGRH
IRLEPQSWRRDEARASSLVLIGAGLPADTALARLRDTVHAEPEPPDEQAMLGVWRYVPH

Specific function: The presence of P47K is critical for the expression of the nitrile hydratase genes. May stabilize or activate the nitrile hydratase proteins [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=358, Percent_Identity=27.6536312849162, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI126722884, Length=358, Percent_Identity=27.3743016759777, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI148727351, Length=358, Percent_Identity=27.0949720670391, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI146231952, Length=358, Percent_Identity=26.8156424581006, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI223941779, Length=337, Percent_Identity=27.5964391691395, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI223941776, Length=338, Percent_Identity=27.2189349112426, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI119120938, Length=349, Percent_Identity=24.9283667621776, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI87082430, Length=330, Percent_Identity=30, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788499, Length=195, Percent_Identity=28.7179487179487, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324356, Length=258, Percent_Identity=28.2945736434109, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 41107; Mature: 40976

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHGGLLVAGLGRCGAGGARDRWLTPAAGGPVAAPRVVGVSERIPVLIVAGFLGAGKTTM
CCCCCEEEEECCCCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCEEEEEECCCCCHHHH
LNHLLRDDSGTRIGVVVNDFGAVNIDAMLVAGQVDAMVSLGNGCVCCAIDVSELDEMFER
HHHHHHCCCCCEEEEEEECCCCEEEEEEEEECCHHEEEECCCCEEEEEECHHHHHHHHHH
LTQPQAGIDVIVVEASGLAEPGNLIRMVLGSENPRIRYGGLIEVVDAEQFPDSRARHPEL
HCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEECCEEEEEECCCCCCCCCCCCHH
AGHLRMADLVVLNKADRVEPGVLDRLRAEIAEHARGVPVYATAHGRIDPALLFDPPARER
HHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCCC
TPVAEQLSFDELWREHDHGDPGHRHLHDDYTSVSFTSDRDLHPRRLIGVLEDPPPGLFRA
CCHHHHCCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHEEEECCCCCCCEEC
KGVLAFAGDHRKFTLHVVGRHIRLEPQSWRRDEARASSLVLIGAGLPADTALARLRDTVH
CEEEEEECCCCEEEEEEECCEEEECCHHHCCHHHCCCEEEEEECCCCHHHHHHHHHHHHC
AEPEPPDEQAMLGVWRYVPH
CCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SHGGLLVAGLGRCGAGGARDRWLTPAAGGPVAAPRVVGVSERIPVLIVAGFLGAGKTTM
CCCCEEEEECCCCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCEEEEEECCCCCHHHH
LNHLLRDDSGTRIGVVVNDFGAVNIDAMLVAGQVDAMVSLGNGCVCCAIDVSELDEMFER
HHHHHHCCCCCEEEEEEECCCCEEEEEEEEECCHHEEEECCCCEEEEEECHHHHHHHHHH
LTQPQAGIDVIVVEASGLAEPGNLIRMVLGSENPRIRYGGLIEVVDAEQFPDSRARHPEL
HCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEECCEEEEEECCCCCCCCCCCCHH
AGHLRMADLVVLNKADRVEPGVLDRLRAEIAEHARGVPVYATAHGRIDPALLFDPPARER
HHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCCC
TPVAEQLSFDELWREHDHGDPGHRHLHDDYTSVSFTSDRDLHPRRLIGVLEDPPPGLFRA
CCHHHHCCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHEEEECCCCCCCEEC
KGVLAFAGDHRKFTLHVVGRHIRLEPQSWRRDEARASSLVLIGAGLPADTALARLRDTVH
CEEEEEECCCCEEEEEEECCEEEECCHHHCCHHHCCCEEEEEECCCCHHHHHHHHHHHHC
AEPEPPDEQAMLGVWRYVPH
CCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2013568 [H]