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The map label for this gene is yxjL [H]

Identifier: 54026224

GI number: 54026224

Start: 4406607

End: 4407269

Strand: Reverse

Name: yxjL [H]

Synonym: nfa42530

Alternate gene names: 54026224

Gene position: 4407269-4406607 (Counterclockwise)

Preceding gene: 54026225

Following gene: 54026222

Centisome position: 73.2

GC content: 69.83

Gene sequence:

>663_bases
GTGGCAACAACGGTTCTCATCGCCGACGACCAGGCAATGGTGCGGCAGGGCTTCGGCGCGCTGCTGGCCGCCCAACCAGA
CATCAGCGTGGTCGGCGACGCGCCGGACGGCAAGGTCGCGGTCGCCGAGGCCAAGCGCCTGCGTCCGGATGTGGTGCTCA
TGGACGTACGCATGCCGGAGATGAACGGACTCGACGCCGCGCGGGCCATCCTCGCGGCCGGCTTCGATCCGCCGGTGCGG
GTGTTGATGCTCACCACGTTCGACATCGACGACTACGTCTACGAGGCGCTGAGCATCGGTGCCAGCGGGTTCCTGCTCAA
GGACGCCCCCGCCGAGGAACTGGTGCGCGCGGTGCGGGTGGTCGCCGAAGGGCAGGCGCTGCTCGCGCCGACGGTCACCC
GCAGGCTCATCGCCGAGGTCACCAGCCGCCGCGCCGCGAGCCGCAAACCCGCCCCGGAACTGGCCGCACTCACCCCGCGG
GAACGGGAAGTGCTCGAGCTGGTCGCCCGCGGCATGTCCAACACCGAGATCGCCGAGGCGCTCTTCGTCGCCGAGCAGAC
GGTGAAAACCCATGTCTCCAAGGTCTTCTCGAAGCTGAACCTGCGCGACCGGGCCCAGGCGGTGGTGCTGGCCTACGAAT
CCGGGCTGGTCACGCCGGGCTGA

Upstream 100 bases:

>100_bases
CGCAGCCCGCGCCGGTCGACGCATCCGGTCGCGGGGCGTGAGCACCGCGCGATCGAACACCACACCGGGGAGTCGGCCGC
GCGGCAATTAGGGTGGGCGA

Downstream 100 bases:

>100_bases
TCCGGCGGTCAGTGCGCGCAGTGGCCGCCGCGCAGTTGATCCAGGTGCCGGGCCAGCAGCGCGGCCATGTCGTCGAGCAG
GTGGGTGGCGTCGGTGAAGT

Product: putative two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MATTVLIADDQAMVRQGFGALLAAQPDISVVGDAPDGKVAVAEAKRLRPDVVLMDVRMPEMNGLDAARAILAAGFDPPVR
VLMLTTFDIDDYVYEALSIGASGFLLKDAPAEELVRAVRVVAEGQALLAPTVTRRLIAEVTSRRAASRKPAPELAALTPR
EREVLELVARGMSNTEIAEALFVAEQTVKTHVSKVFSKLNLRDRAQAVVLAYESGLVTPG

Sequences:

>Translated_220_residues
MATTVLIADDQAMVRQGFGALLAAQPDISVVGDAPDGKVAVAEAKRLRPDVVLMDVRMPEMNGLDAARAILAAGFDPPVR
VLMLTTFDIDDYVYEALSIGASGFLLKDAPAEELVRAVRVVAEGQALLAPTVTRRLIAEVTSRRAASRKPAPELAALTPR
EREVLELVARGMSNTEIAEALFVAEQTVKTHVSKVFSKLNLRDRAQAVVLAYESGLVTPG
>Mature_219_residues
ATTVLIADDQAMVRQGFGALLAAQPDISVVGDAPDGKVAVAEAKRLRPDVVLMDVRMPEMNGLDAARAILAAGFDPPVRV
LMLTTFDIDDYVYEALSIGASGFLLKDAPAEELVRAVRVVAEGQALLAPTVTRRLIAEVTSRRAASRKPAPELAALTPRE
REVLELVARGMSNTEIAEALFVAEQTVKTHVSKVFSKLNLRDRAQAVVLAYESGLVTPG

Specific function: Probable member of the two-component regulatory system yxjM/yxjL [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=36.8932038834951, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787473, Length=210, Percent_Identity=35.7142857142857, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788222, Length=215, Percent_Identity=32.5581395348837, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=34, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1786747, Length=201, Percent_Identity=26.865671641791, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788712, Length=199, Percent_Identity=24.1206030150754, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787277, Length=138, Percent_Identity=31.1594202898551, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87082052, Length=105, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23518; Mature: 23386

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTVLIADDQAMVRQGFGALLAAQPDISVVGDAPDGKVAVAEAKRLRPDVVLMDVRMPE
CCEEEEEECCHHHHHHCCHHEEECCCCCEEEECCCCCCEEHHHHHHCCCCEEEEEECCCC
MNGLDAARAILAAGFDPPVRVLMLTTFDIDDYVYEALSIGASGFLLKDAPAEELVRAVRV
CCCHHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHH
VAEGQALLAPTVTRRLIAEVTSRRAASRKPAPELAALTPREREVLELVARGMSNTEIAEA
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCHHHHHH
LFVAEQTVKTHVSKVFSKLNLRDRAQAVVLAYESGLVTPG
HHHHHHHHHHHHHHHHHHCCCHHHHHEEEEEECCCCCCCC
>Mature Secondary Structure 
ATTVLIADDQAMVRQGFGALLAAQPDISVVGDAPDGKVAVAEAKRLRPDVVLMDVRMPE
CEEEEEECCHHHHHHCCHHEEECCCCCEEEECCCCCCEEHHHHHHCCCCEEEEEECCCC
MNGLDAARAILAAGFDPPVRVLMLTTFDIDDYVYEALSIGASGFLLKDAPAEELVRAVRV
CCCHHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHH
VAEGQALLAPTVTRRLIAEVTSRRAASRKPAPELAALTPREREVLELVARGMSNTEIAEA
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCHHHHHH
LFVAEQTVKTHVSKVFSKLNLRDRAQAVVLAYESGLVTPG
HHHHHHHHHHHHHHHHHHCCCHHHHHEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]