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The map label for this gene is pbpA [H]

Identifier: 54026087

GI number: 54026087

Start: 4264215

End: 4266005

Strand: Reverse

Name: pbpA [H]

Synonym: nfa41160

Alternate gene names: 54026087

Gene position: 4266005-4264215 (Counterclockwise)

Preceding gene: 54026088

Following gene: 54026083

Centisome position: 70.85

GC content: 70.63

Gene sequence:

>1791_bases
ATGTCGACGCGCATACTGATCCCGGTCGTCGTCGCGATGTTGGTCGCGGCGGCGGTGGTGGGCTGCTCGTCCGGCCCGCA
GGGGCCGGTTCCGGTGGCCGAGTCCTTCCTCTCCGCCTTCGCCGCCCGTGAGCTCGACGCCGCCGCGGAGCTCACCAGCC
AGCCCGAGAAGGCAAGTGCCGCCTTGGCTTCGGCGTGGGAGAAGCTGCAGGCCGAGGAGCTGACCGCCCGCTCGGGTGCG
GCCAGGGTGACCGGCGACACCGCGACCGTCGACTACAGCTACGAGTGGCGCCTGCCCAAGAACCGGGTCTGGAGCTACAC
CGGACAGTTGCAGATGGGCCGCAGCGAGGGCCGCTGGACGGTGCGCTGGACCTCCTCGAACATCCACCCTCGTCTCGGCG
ACACCCAGACGTTGGCGCTGCGCACCACGCCCGCGCCGCGCGCCCGCGTCAACGAGCAGTCCGGCAGCGATGTGCTGGTG
CCGGGCGAGGTGACGCGGGTGGCGTTCTCGCCCGCGGACGCGCCGGATCCGGCGAAGGTGGCCGGTGCGCTGTCGGCGGC
GCTGCTGCGCTTCGACAAGAAGCTCACCCCGGAGGCGATCCTGCGCGCGGCCCGCGCCGCCGACGGGCCCTACACCGTCG
CGCTGCTCAGCGAGGTCGAATACAACGAGGTCGGTGCCCTGCTCATCGGGTTGCCGGGGGTGCGGCTCAACCAGGAGTGG
GACATGGTGTCCACCGAGCGTGGCTTCGCGCCCGACCTGCTGACCCAGATCCGCAAGACCGTGATCGCCGAGGTGGACGG
CAAGGCGGGCTGGAGCGTGGTGACCCAGAACGCCAACGGCGTCGACACCGATGTGCTCACCGAGGTGCCCGCGCAGCCCG
CGCCGTCGTTCGCGCTGAGCATCGACCGGTATGTGCAGAACGCGGCGCAGCGTGCGGTGGACGTGCCAAAGGAACAAACG
ATGATGGTCGTGATCCGGCCGTCGACCGGCGCGATCCTGGCGGTGGCCCAGAACGAGGCGGCCGATCGGGACGGGCCGAT
GGCCACCATCGGGCAGTATCCGCCCGGCTCGATCTTCAAGACGGTCACCGCGGCGGCGGCCATGCACGAAGGGCTGGCGA
CCCCGGACACCATCGTGCCGTGCCCGAGCCAGATCGTCATCGGCGAGCGGACCATCCCGAACTACAACATGTTCAGTGTC
GGCAGCGTGCCGATGGCCACCGCGTACGAGCGCTCGTGCAACACCTCCTTCGCCAAGCTGGCCAGCGAGCTGCCCGCCGA
CGCGTTGCACGTGACCGCGGCGGGGCTGGGCGTGGGACCCGACTACACCGTGGTCGGACTGCCGACGACCTCGGGTTCGG
TGCCGCCCGCCGAGGACATGGTGCAGCGCAGCGAGGACGGCATCGGGCAGGGCAAGGTCGTGGTCAGCCCGTTCGGGATG
GCGCTGATGGCGGCGACGGTCGCCAACGGCAGCGCCCCGGTGCCGTGGCTGATCGGCGGGCGGGAGACGATCGTGGACGG
CGAGCGCCCGGCGATCGACCCGGCGGTGATCGAGGGCCTGCGGCTGATGATGCGCAAGGTGATCACCGGCGGAACCGCCA
CCCGCATCGTCGACCAGGGCGAGGTCTACGGCAAGACCGGTGAAGCCGAGGTGGAGGGCGGTTCGCACTCCTGGTTCGTG
GGATACCGCGGCGACATCGCGTTCGCCACGTTGCTGGTCAAGGGTGGCAGCTCCGACAACGCGGTCGCGGTGACCAGGGA
CATGTTCGCGGCGTTGCCGCCGGAGTACTGA

Upstream 100 bases:

>100_bases
ACCTTCGCCACCGTCCTGCTCGACTGAACGCGCGCCCCGCGGCGCGAGATTCGGTGCGCCGCAGGAGTTTGCCGTTCGGT
GGCCAGTACCATCGGCAGCG

Downstream 100 bases:

>100_bases
GCGCTCAGCGGGCCCGGGTGAGGCCGACGGCCACCACCGAGCCGAACCGCTGGGTCGGTCCCGCGGCCTGGGGATCCGGG
ACGGCCGCGGTGCAGCTGTG

Product: putative penicillin-binding protein

Products: NA

Alternate protein names: PBPA [H]

Number of amino acids: Translated: 596; Mature: 595

Protein sequence:

>596_residues
MSTRILIPVVVAMLVAAAVVGCSSGPQGPVPVAESFLSAFAARELDAAAELTSQPEKASAALASAWEKLQAEELTARSGA
ARVTGDTATVDYSYEWRLPKNRVWSYTGQLQMGRSEGRWTVRWTSSNIHPRLGDTQTLALRTTPAPRARVNEQSGSDVLV
PGEVTRVAFSPADAPDPAKVAGALSAALLRFDKKLTPEAILRAARAADGPYTVALLSEVEYNEVGALLIGLPGVRLNQEW
DMVSTERGFAPDLLTQIRKTVIAEVDGKAGWSVVTQNANGVDTDVLTEVPAQPAPSFALSIDRYVQNAAQRAVDVPKEQT
MMVVIRPSTGAILAVAQNEAADRDGPMATIGQYPPGSIFKTVTAAAAMHEGLATPDTIVPCPSQIVIGERTIPNYNMFSV
GSVPMATAYERSCNTSFAKLASELPADALHVTAAGLGVGPDYTVVGLPTTSGSVPPAEDMVQRSEDGIGQGKVVVSPFGM
ALMAATVANGSAPVPWLIGGRETIVDGERPAIDPAVIEGLRLMMRKVITGGTATRIVDQGEVYGKTGEAEVEGGSHSWFV
GYRGDIAFATLLVKGGSSDNAVAVTRDMFAALPPEY

Sequences:

>Translated_596_residues
MSTRILIPVVVAMLVAAAVVGCSSGPQGPVPVAESFLSAFAARELDAAAELTSQPEKASAALASAWEKLQAEELTARSGA
ARVTGDTATVDYSYEWRLPKNRVWSYTGQLQMGRSEGRWTVRWTSSNIHPRLGDTQTLALRTTPAPRARVNEQSGSDVLV
PGEVTRVAFSPADAPDPAKVAGALSAALLRFDKKLTPEAILRAARAADGPYTVALLSEVEYNEVGALLIGLPGVRLNQEW
DMVSTERGFAPDLLTQIRKTVIAEVDGKAGWSVVTQNANGVDTDVLTEVPAQPAPSFALSIDRYVQNAAQRAVDVPKEQT
MMVVIRPSTGAILAVAQNEAADRDGPMATIGQYPPGSIFKTVTAAAAMHEGLATPDTIVPCPSQIVIGERTIPNYNMFSV
GSVPMATAYERSCNTSFAKLASELPADALHVTAAGLGVGPDYTVVGLPTTSGSVPPAEDMVQRSEDGIGQGKVVVSPFGM
ALMAATVANGSAPVPWLIGGRETIVDGERPAIDPAVIEGLRLMMRKVITGGTATRIVDQGEVYGKTGEAEVEGGSHSWFV
GYRGDIAFATLLVKGGSSDNAVAVTRDMFAALPPEY
>Mature_595_residues
STRILIPVVVAMLVAAAVVGCSSGPQGPVPVAESFLSAFAARELDAAAELTSQPEKASAALASAWEKLQAEELTARSGAA
RVTGDTATVDYSYEWRLPKNRVWSYTGQLQMGRSEGRWTVRWTSSNIHPRLGDTQTLALRTTPAPRARVNEQSGSDVLVP
GEVTRVAFSPADAPDPAKVAGALSAALLRFDKKLTPEAILRAARAADGPYTVALLSEVEYNEVGALLIGLPGVRLNQEWD
MVSTERGFAPDLLTQIRKTVIAEVDGKAGWSVVTQNANGVDTDVLTEVPAQPAPSFALSIDRYVQNAAQRAVDVPKEQTM
MVVIRPSTGAILAVAQNEAADRDGPMATIGQYPPGSIFKTVTAAAAMHEGLATPDTIVPCPSQIVIGERTIPNYNMFSVG
SVPMATAYERSCNTSFAKLASELPADALHVTAAGLGVGPDYTVVGLPTTSGSVPPAEDMVQRSEDGIGQGKVVVSPFGMA
LMAATVANGSAPVPWLIGGRETIVDGERPAIDPAVIEGLRLMMRKVITGGTATRIVDQGEVYGKTGEAEVEGGSHSWFVG
YRGDIAFATLLVKGGSSDNAVAVTRDMFAALPPEY

Specific function: Cell wall formation. Plays an important role in cell division and cell shape maintenance by cross-linking adjacent peptidoglycan chains through transpeptidation [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Probable). Note=Localized to the division site (septum) along with newly synthesized peptidoglycan, between segregated nucleoids (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 62612; Mature: 62480

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRILIPVVVAMLVAAAVVGCSSGPQGPVPVAESFLSAFAARELDAAAELTSQPEKASA
CCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALASAWEKLQAEELTARSGAARVTGDTATVDYSYEWRLPKNRVWSYTGQLQMGRSEGRWT
HHHHHHHHHHHHHHHHCCCCCEEECCEEEEEEEEEEECCCCCEEEEECCEEECCCCCEEE
VRWTSSNIHPRLGDTQTLALRTTPAPRARVNEQSGSDVLVPGEVTRVAFSPADAPDPAKV
EEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCHHHH
AGALSAALLRFDKKLTPEAILRAARAADGPYTVALLSEVEYNEVGALLIGLPGVRLNQEW
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHCEEEEECCCCEECCCC
DMVSTERGFAPDLLTQIRKTVIAEVDGKAGWSVVTQNANGVDTDVLTEVPAQPAPSFALS
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCCCCHHHHH
IDRYVQNAAQRAVDVPKEQTMMVVIRPSTGAILAVAQNEAADRDGPMATIGQYPPGSIFK
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCEEECCCCCCCHHHH
TVTAAAAMHEGLATPDTIVPCPSQIVIGERTIPNYNMFSVGSVPMATAYERSCNTSFAKL
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCCHHHHHHHCCHHHHHH
ASELPADALHVTAAGLGVGPDYTVVGLPTTSGSVPPAEDMVQRSEDGIGQGKVVVSPFGM
HHHCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCEEEECCHHH
ALMAATVANGSAPVPWLIGGRETIVDGERPAIDPAVIEGLRLMMRKVITGGTATRIVDQG
HHHHHHHCCCCCCCCEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECC
EVYGKTGEAEVEGGSHSWFVGYRGDIAFATLLVKGGSSDNAVAVTRDMFAALPPEY
CEECCCCCEEECCCCCEEEEEECCCEEEEEEEEECCCCCCEEEEEHHHHHHCCCCC
>Mature Secondary Structure 
STRILIPVVVAMLVAAAVVGCSSGPQGPVPVAESFLSAFAARELDAAAELTSQPEKASA
CCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALASAWEKLQAEELTARSGAARVTGDTATVDYSYEWRLPKNRVWSYTGQLQMGRSEGRWT
HHHHHHHHHHHHHHHHCCCCCEEECCEEEEEEEEEEECCCCCEEEEECCEEECCCCCEEE
VRWTSSNIHPRLGDTQTLALRTTPAPRARVNEQSGSDVLVPGEVTRVAFSPADAPDPAKV
EEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCHHHH
AGALSAALLRFDKKLTPEAILRAARAADGPYTVALLSEVEYNEVGALLIGLPGVRLNQEW
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHCEEEEECCCCEECCCC
DMVSTERGFAPDLLTQIRKTVIAEVDGKAGWSVVTQNANGVDTDVLTEVPAQPAPSFALS
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCCCCCHHHHH
IDRYVQNAAQRAVDVPKEQTMMVVIRPSTGAILAVAQNEAADRDGPMATIGQYPPGSIFK
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCEEECCCCCCCHHHH
TVTAAAAMHEGLATPDTIVPCPSQIVIGERTIPNYNMFSVGSVPMATAYERSCNTSFAKL
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCCHHHHHHHCCHHHHHH
ASELPADALHVTAAGLGVGPDYTVVGLPTTSGSVPPAEDMVQRSEDGIGQGKVVVSPFGM
HHHCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCEEEECCHHH
ALMAATVANGSAPVPWLIGGRETIVDGERPAIDPAVIEGLRLMMRKVITGGTATRIVDQG
HHHHHHHCCCCCCCCEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECC
EVYGKTGEAEVEGGSHSWFVGYRGDIAFATLLVKGGSSDNAVAVTRDMFAALPPEY
CEECCCCCEEECCCCCEEEEEECCCEEEEEEEEECCCCCCEEEEEHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA