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The map label for this gene is cobB [H]

Identifier: 54026052

GI number: 54026052

Start: 4231502

End: 4232926

Strand: Reverse

Name: cobB [H]

Synonym: nfa40810

Alternate gene names: 54026052

Gene position: 4232926-4231502 (Counterclockwise)

Preceding gene: 54026053

Following gene: 54026051

Centisome position: 70.3

GC content: 75.93

Gene sequence:

>1425_bases
GTGAACGGCCCGGTCCCCGCGGTGGTCGTCGCCGCGCCCGCCTCGGGGAGCGGCAAGACCACGCTGGCCACCGGCTTGAT
CGGCGCGCTGCGCCGCGCCGGGCACCGGGTCGCGCCGTTCAAGGTCGGGCCCGACTACATCGATCCCGGCTATCACGGTC
TGGCGGCGGGACGGCCCGGCCGCAACCTCGACCCGGTGCTGGTGGGCGCCGAGCGGATCGCGCCGCTGTATCGGCACGGC
ACGGTGGGCTGCGACCTGGCCGTGGTGGAGGGGGTGATGGGCCTGTTCGACGGCCGCATCGACGAGGGCGATCCGGCCCC
GGTCGCGGAGGGCTCCACCGCCCAGGTGGCCGGGCTGCTCGGCGCGCCGGTGGTGCTGGTCGTCGACGCCCGCGGCCACA
GTCAGAGCCTGGCCGCGCTGCTGCACGGCTTCGCCACCTTCGACAGCGGCGTGCGGCTCGGCGGTGTGATCCTCAACCGG
GTGGGCAGCGAACGGCACGAACAGGTGCTGCGCGCGGCCTGCGCCCGCGTGGGGCTGCCCGTGCTCGGCGCGCTGCCGCG
GATGGGGGCACTCGAGGTCCCGTCCCGGCACCTGGGTCTCATCCCGGCCGTGGAGCACGGTCGCGCCGCCACCGACGCCG
TGGCGGCGATGACCGATCTCGTCGCCGCCCACGTGGACCTGGGCGCCGTCGCGGCCCTGGCCCGGTGCACGGTGGCCGAG
CCCGCGTGGGATCCGGCGGACGTGGTCCGCACTGCGCCGGCCGACCACCGGGGGACCACCGATGCGCAGCCTGCCGCGGC
GGACGGACCGGTGATCGCGATGGCCGGTGGACCCGCCTTCACCTTCGGCTACGCCGAGCACCGCGAGCTGCTCGCGGCGG
CAGGCGCGCGGGTGGTCGTGTTCGATCCCTTGCGTGACGAATTGCCCACGGGCGCAGCCGGTCTGGTGTTGCCCGGCGGG
TTCCCCGAGGAGCACGCGGCGGCGCTGGCGGCCAACACCCCGTTGCTCACCGAGGTGCGCGAACGCGCCGCCGCCGGGCT
GCCGATCCACGCCGAATGCGCGGGCCTGCTTTATCTCACCCGATCCCTGGACGGCCACGCGCTGGCCGGGGTGGTCGACG
CCGAGGCCGAATTCGGTCCGCGTCTGACCCTCGGGTACCGCGAGGCCGTCGCGCTGGCCGATTCCCCGCTGTGGCAGGCC
GGCGAACGCGTCCGCGGCCACGAATTCCACCGCACCCGCCTGATCACCGCCGTGGTCGACCGGCCCGCCTGGGGCTGGCG
CGACCCCGCCGGTGCCACCGTCCGCGAAGGGCTGCTCACCCGCCGCGTGCACGCCTCGTACCTGCACACCCATCCCGCCG
GAAACCCGAGCGCCACGGTCCGGTTCGTCGCGGCGGCCGCCGACCACGCCCGTGCGCGGCGGTGA

Upstream 100 bases:

>100_bases
CGCCGTCCGCGCTGCTGGAGGCCGCCGACCTGGTGACCGAGATGACGAAGGTGAAGCATCCGATGGACGCGGGCCGCAAG
GGCCAGCGGGGCATCGAGTG

Downstream 100 bases:

>100_bases
GCCGGGCGGCGCCGATCCGCCCCACGCCGAGCACGGTGATCCGGGCGCGCCGACGCCCGCCGAACCACGGGGGAACCTCG
TGGTCGGGGTCGGATGCCGA

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MNGPVPAVVVAAPASGSGKTTLATGLIGALRRAGHRVAPFKVGPDYIDPGYHGLAAGRPGRNLDPVLVGAERIAPLYRHG
TVGCDLAVVEGVMGLFDGRIDEGDPAPVAEGSTAQVAGLLGAPVVLVVDARGHSQSLAALLHGFATFDSGVRLGGVILNR
VGSERHEQVLRAACARVGLPVLGALPRMGALEVPSRHLGLIPAVEHGRAATDAVAAMTDLVAAHVDLGAVAALARCTVAE
PAWDPADVVRTAPADHRGTTDAQPAAADGPVIAMAGGPAFTFGYAEHRELLAAAGARVVVFDPLRDELPTGAAGLVLPGG
FPEEHAAALAANTPLLTEVRERAAAGLPIHAECAGLLYLTRSLDGHALAGVVDAEAEFGPRLTLGYREAVALADSPLWQA
GERVRGHEFHRTRLITAVVDRPAWGWRDPAGATVREGLLTRRVHASYLHTHPAGNPSATVRFVAAAADHARARR

Sequences:

>Translated_474_residues
MNGPVPAVVVAAPASGSGKTTLATGLIGALRRAGHRVAPFKVGPDYIDPGYHGLAAGRPGRNLDPVLVGAERIAPLYRHG
TVGCDLAVVEGVMGLFDGRIDEGDPAPVAEGSTAQVAGLLGAPVVLVVDARGHSQSLAALLHGFATFDSGVRLGGVILNR
VGSERHEQVLRAACARVGLPVLGALPRMGALEVPSRHLGLIPAVEHGRAATDAVAAMTDLVAAHVDLGAVAALARCTVAE
PAWDPADVVRTAPADHRGTTDAQPAAADGPVIAMAGGPAFTFGYAEHRELLAAAGARVVVFDPLRDELPTGAAGLVLPGG
FPEEHAAALAANTPLLTEVRERAAAGLPIHAECAGLLYLTRSLDGHALAGVVDAEAEFGPRLTLGYREAVALADSPLWQA
GERVRGHEFHRTRLITAVVDRPAWGWRDPAGATVREGLLTRRVHASYLHTHPAGNPSATVRFVAAAADHARARR
>Mature_474_residues
MNGPVPAVVVAAPASGSGKTTLATGLIGALRRAGHRVAPFKVGPDYIDPGYHGLAAGRPGRNLDPVLVGAERIAPLYRHG
TVGCDLAVVEGVMGLFDGRIDEGDPAPVAEGSTAQVAGLLGAPVVLVVDARGHSQSLAALLHGFATFDSGVRLGGVILNR
VGSERHEQVLRAACARVGLPVLGALPRMGALEVPSRHLGLIPAVEHGRAATDAVAAMTDLVAAHVDLGAVAALARCTVAE
PAWDPADVVRTAPADHRGTTDAQPAAADGPVIAMAGGPAFTFGYAEHRELLAAAGARVVVFDPLRDELPTGAAGLVLPGG
FPEEHAAALAANTPLLTEVRERAAAGLPIHAECAGLLYLTRSLDGHALAGVVDAEAEFGPRLTLGYREAVALADSPLWQA
GERVRGHEFHRTRLITAVVDRPAWGWRDPAGATVREGLLTRRVHASYLHTHPAGNPSATVRFVAAAADHARARR

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 48825; Mature: 48825

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00191 CYTOCHROME_B5_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGPVPAVVVAAPASGSGKTTLATGLIGALRRAGHRVAPFKVGPDYIDPGYHGLAAGRPG
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEECCEECCCCCCCCCCCCCCCCCCC
RNLDPVLVGAERIAPLYRHGTVGCDLAVVEGVMGLFDGRIDEGDPAPVAEGSTAQVAGLL
CCCCCEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
GAPVVLVVDARGHSQSLAALLHGFATFDSGVRLGGVILNRVGSERHEQVLRAACARVGLP
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCH
VLGALPRMGALEVPSRHLGLIPAVEHGRAATDAVAAMTDLVAAHVDLGAVAALARCTVAE
HHHHCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PAWDPADVVRTAPADHRGTTDAQPAAADGPVIAMAGGPAFTFGYAEHRELLAAAGARVVV
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHCCCEEEE
FDPLRDELPTGAAGLVLPGGFPEEHAAALAANTPLLTEVRERAAAGLPIHAECAGLLYLT
ECCHHHHCCCCCCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
RSLDGHALAGVVDAEAEFGPRLTLGYREAVALADSPLWQAGERVRGHEFHRTRLITAVVD
HCCCCCEEEEEEECCCCCCCEEEECHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHC
RPAWGWRDPAGATVREGLLTRRVHASYLHTHPAGNPSATVRFVAAAADHARARR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHCCC
>Mature Secondary Structure
MNGPVPAVVVAAPASGSGKTTLATGLIGALRRAGHRVAPFKVGPDYIDPGYHGLAAGRPG
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEECCEECCCCCCCCCCCCCCCCCCC
RNLDPVLVGAERIAPLYRHGTVGCDLAVVEGVMGLFDGRIDEGDPAPVAEGSTAQVAGLL
CCCCCEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
GAPVVLVVDARGHSQSLAALLHGFATFDSGVRLGGVILNRVGSERHEQVLRAACARVGLP
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCH
VLGALPRMGALEVPSRHLGLIPAVEHGRAATDAVAAMTDLVAAHVDLGAVAALARCTVAE
HHHHCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PAWDPADVVRTAPADHRGTTDAQPAAADGPVIAMAGGPAFTFGYAEHRELLAAAGARVVV
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHCCCEEEE
FDPLRDELPTGAAGLVLPGGFPEEHAAALAANTPLLTEVRERAAAGLPIHAECAGLLYLT
ECCHHHHCCCCCCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
RSLDGHALAGVVDAEAEFGPRLTLGYREAVALADSPLWQAGERVRGHEFHRTRLITAVVD
HCCCCCEEEEEEECCCCCCCEEEECHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHC
RPAWGWRDPAGATVREGLLTRRVHASYLHTHPAGNPSATVRFVAAAADHARARR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]