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The map label for this gene is nusA [H]

Identifier: 54026039

GI number: 54026039

Start: 4217532

End: 4218560

Strand: Reverse

Name: nusA [H]

Synonym: nfa40680

Alternate gene names: 54026039

Gene position: 4218560-4217532 (Counterclockwise)

Preceding gene: 54026040

Following gene: 54026038

Centisome position: 70.06

GC content: 70.94

Gene sequence:

>1029_bases
ATGAACATCGAAATCGAAGCCCTGCGCGCGATCGTCGCCGACAAGGGGATCTCGATCGAGACGGTGATCTCCGCGATCGA
GTCGGCCCTGCTCACCGCCTACCGGCACACCGAGGGCCACCAGCCCAACGCGCGCGTCGACATCAACCAGCGCACCGGCG
CGGTCCGGGTGATGGCGCGCGAGCTCGACGCCGACGGCAACGTCATCTCCGAGTGGGACGACACCCCCGAAGGCTTCGGG
CGCATCGCCGCGACCACCGCCCGGCAGGTCGTGTTGCAGCGCCTGCGCGACGCGGAGAACGAGAAGTCCTTCGGCGAGTT
CTCCACCCACGAGGGCGACATCGTCGGCGGTGTGGTGCAGCGCGACGCGCGCGCCAACGCCCGCGGCACCGTCGTGGTCC
GCATAGGCAGCGAACTGCACGGCACCGAGGGCCTGATCCCGCCCGCCGAGCAGGTGCCGGGCGAGACCTACGAGCACGGT
GACCGGATCAAGTGCTACGTCGTCGGCGTCTCGCGCGGTCCGCGCGGCCCGCAGATCACGCTCTCGCGCACACACCCCAA
CCTGGTCCGCCGCCTCTTCGCACTCGAGGTGCCCGAGATCGCCGACGGCTCGGTGGAGATCGTGGCGGTCGCCCGCGAGG
CCGGGCATCGCTCCAAGATCGCGGTGCGCTCCACGGTGCCCGGCGTCAACGCCAAGGGCGCCTGCATCGGCCCGATGGGC
CAGCGCGTGCGCAACGTGATGAGCGAGCTGGCCGGGGAGAAGATCGACATCATCGACTACGCCGACGACCCGGCGACCTT
CGTCGGCAACGCGCTCTCGCCCTCGAAGGTGGTCTCGGTCACCATCGTCGATCCCGACGCCCGCGCGGCGCGGGTGGTGG
TCCCGGACTTCCAGCTCTCGCTGGCCATCGGCAAGGAAGGGCAGAACGCGCGGCTCGCGGCCCGGCTCACCGGCTGGCGC
ATCGACATCCGCAGCGACGCCGCCCCGGACGTGGGCGACGGCATGCGGACGGAGGCGCATCGCAGTTGA

Upstream 100 bases:

>100_bases
GGCCGGATCCCGGTACCGACCGGGCAATCGCCGCCGACGGGGCGATCAGCGAGGAAACATCGACAGCAGCAGCGTCCGAC
CCGACCGAAGGGATCGAGGA

Downstream 100 bases:

>100_bases
GCGGAGCCCGCGGCACGAGCCGGGAATCAGCGGCCCCCGACGGCGCGTTGAGCATGTCGATGGGGGACGGGTTCGGTGAT
CACGGTGGTGCGGCTGTAGA

Product: transcription elongation factor NusA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNIEIEALRAIVADKGISIETVISAIESALLTAYRHTEGHQPNARVDINQRTGAVRVMARELDADGNVISEWDDTPEGFG
RIAATTARQVVLQRLRDAENEKSFGEFSTHEGDIVGGVVQRDARANARGTVVVRIGSELHGTEGLIPPAEQVPGETYEHG
DRIKCYVVGVSRGPRGPQITLSRTHPNLVRRLFALEVPEIADGSVEIVAVAREAGHRSKIAVRSTVPGVNAKGACIGPMG
QRVRNVMSELAGEKIDIIDYADDPATFVGNALSPSKVVSVTIVDPDARAARVVVPDFQLSLAIGKEGQNARLAARLTGWR
IDIRSDAAPDVGDGMRTEAHRS

Sequences:

>Translated_342_residues
MNIEIEALRAIVADKGISIETVISAIESALLTAYRHTEGHQPNARVDINQRTGAVRVMARELDADGNVISEWDDTPEGFG
RIAATTARQVVLQRLRDAENEKSFGEFSTHEGDIVGGVVQRDARANARGTVVVRIGSELHGTEGLIPPAEQVPGETYEHG
DRIKCYVVGVSRGPRGPQITLSRTHPNLVRRLFALEVPEIADGSVEIVAVAREAGHRSKIAVRSTVPGVNAKGACIGPMG
QRVRNVMSELAGEKIDIIDYADDPATFVGNALSPSKVVSVTIVDPDARAARVVVPDFQLSLAIGKEGQNARLAARLTGWR
IDIRSDAAPDVGDGMRTEAHRS
>Mature_342_residues
MNIEIEALRAIVADKGISIETVISAIESALLTAYRHTEGHQPNARVDINQRTGAVRVMARELDADGNVISEWDDTPEGFG
RIAATTARQVVLQRLRDAENEKSFGEFSTHEGDIVGGVVQRDARANARGTVVVRIGSELHGTEGLIPPAEQVPGETYEHG
DRIKCYVVGVSRGPRGPQITLSRTHPNLVRRLFALEVPEIADGSVEIVAVAREAGHRSKIAVRSTVPGVNAKGACIGPMG
QRVRNVMSELAGEKIDIIDYADDPATFVGNALSPSKVVSVTIVDPDARAARVVVPDFQLSLAIGKEGQNARLAARLTGWR
IDIRSDAAPDVGDGMRTEAHRS

Specific function: Participates in both the termination and antitermination of transcription. Interacts with RNA polymerase and binds RNA [H]

COG id: COG0195

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1789560, Length=363, Percent_Identity=34.1597796143251, Blast_Score=195, Evalue=3e-51,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1612 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004087
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004088
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013735
- InterPro:   IPR010213 [H]

Pfam domain/function: PF08529 NusA_N [H]

EC number: NA

Molecular weight: Translated: 36706; Mature: 36706

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEIEALRAIVADKGISIETVISAIESALLTAYRHTEGHQPNARVDINQRTGAVRVMAR
CCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEEE
ELDADGNVISEWDDTPEGFGRIAATTARQVVLQRLRDAENEKSFGEFSTHEGDIVGGVVQ
HHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHH
RDARANARGTVVVRIGSELHGTEGLIPPAEQVPGETYEHGDRIKCYVVGVSRGPRGPQIT
HCCCCCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEE
LSRTHPNLVRRLFALEVPEIADGSVEIVAVAREAGHRSKIAVRSTVPGVNAKGACIGPMG
EECCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCEECHHH
QRVRNVMSELAGEKIDIIDYADDPATFVGNALSPSKVVSVTIVDPDARAARVVVPDFQLS
HHHHHHHHHHCCCEEEEEEECCCCHHHHCCCCCCCCEEEEEEECCCCCEEEEEECCCEEE
LAIGKEGQNARLAARLTGWRIDIRSDAAPDVGDGMRTEAHRS
EEECCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIEIEALRAIVADKGISIETVISAIESALLTAYRHTEGHQPNARVDINQRTGAVRVMAR
CCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEEE
ELDADGNVISEWDDTPEGFGRIAATTARQVVLQRLRDAENEKSFGEFSTHEGDIVGGVVQ
HHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHH
RDARANARGTVVVRIGSELHGTEGLIPPAEQVPGETYEHGDRIKCYVVGVSRGPRGPQIT
HCCCCCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEE
LSRTHPNLVRRLFALEVPEIADGSVEIVAVAREAGHRSKIAVRSTVPGVNAKGACIGPMG
EECCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCEECHHH
QRVRNVMSELAGEKIDIIDYADDPATFVGNALSPSKVVSVTIVDPDARAARVVVPDFQLS
HHHHHHHHHHCCCEEEEEEECCCCHHHHCCCCCCCCEEEEEEECCCCCEEEEEECCCEEE
LAIGKEGQNARLAARLTGWRIDIRSDAAPDVGDGMRTEAHRS
EEECCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]