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The map label for this gene is trmH [C]

Identifier: 54025941

GI number: 54025941

Start: 4160771

End: 4161238

Strand: Reverse

Name: trmH [C]

Synonym: nfa39710

Alternate gene names: 54025941

Gene position: 4161238-4160771 (Counterclockwise)

Preceding gene: 54025942

Following gene: 54025940

Centisome position: 69.11

GC content: 66.45

Gene sequence:

>468_bases
ATGACGACAGGATTCTATGGCGTCGCCGTGTGGCATCCGAAGCATGAAGTGAATGTCGGCACGCTTTGGCGGTCCGCGAT
GACGTATCAGGCGTCGATGCTCGCCACCATCGGGTCGCGGTACAAGCCGCAAGCCTCCGACACGTGCAGAGCGCACAACG
CGATCCCGCTGCACCATTACCGCGACATCGACGACCTGATCGCACACCTGCCGTACGGTTGCCCGCTCGTCGGGGTCGAA
CTCGACGCCCGCGCGGTCTCCCTCAACGAGTTCACCCACCCGGTCCGCGCACTGTACCTGCTCGGCGCCGAGGATCACGG
GCTGCCCGCTGCCGTGCTCGACCGCTGCCACCACGTCGTGCAGATCCCGTCCCCGTCGCCGTGGTCGCTGAACGTGTCCG
TCGCCGGGAGCTTGGTCATGCATGACCGCTGGTCCAAGACCGGCGGGCTTCGGGCGGTGAACGCGTGA

Upstream 100 bases:

>100_bases
GGATGTCCAAGCCGGAACCGCTCATCCACCCTGCCGTGAAGGGTGAAGGCGGGCGCATGTGGATCGAAATCACCTACAGC
ACCACGGGAGAGGCGGCATC

Downstream 100 bases:

>100_bases
ACAGCGAATCCGTAACACCGCCCCCGTCCCCGCCTGCTACGTCACGTGACGAATACCGGATCACCTACCTCGACCCCGGC
ACGGGGGAGGAGTACGTGCT

Product: hypothetical protein

Products: S-adenosyl-L-homocysteine; tRNATyr Containing 2'-O-methylguanosine [C]

Alternate protein names: RNA Methyltransferase; 23S RRNA Methyltransferase; RNA Methyltransferase TrmH Family; Cold-Shock RNA Methyltransferase; rRNA Methylase; TrmH Family RNA Methyltransferase; TRNA/RRNA MethyltransferaU; rRNA Methyltransferase; SpoU RRNA Methylase Family Protein; rRNA Methylase-Family Protein; SpoU Class RRNA Methylase

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MTTGFYGVAVWHPKHEVNVGTLWRSAMTYQASMLATIGSRYKPQASDTCRAHNAIPLHHYRDIDDLIAHLPYGCPLVGVE
LDARAVSLNEFTHPVRALYLLGAEDHGLPAAVLDRCHHVVQIPSPSPWSLNVSVAGSLVMHDRWSKTGGLRAVNA

Sequences:

>Translated_155_residues
MTTGFYGVAVWHPKHEVNVGTLWRSAMTYQASMLATIGSRYKPQASDTCRAHNAIPLHHYRDIDDLIAHLPYGCPLVGVE
LDARAVSLNEFTHPVRALYLLGAEDHGLPAAVLDRCHHVVQIPSPSPWSLNVSVAGSLVMHDRWSKTGGLRAVNA
>Mature_154_residues
TTGFYGVAVWHPKHEVNVGTLWRSAMTYQASMLATIGSRYKPQASDTCRAHNAIPLHHYRDIDDLIAHLPYGCPLVGVEL
DARAVSLNEFTHPVRALYLLGAEDHGLPAAVLDRCHHVVQIPSPSPWSLNVSVAGSLVMHDRWSKTGGLRAVNA

Specific function: Specifically Methylates Guanosine-18 In Various tRNAs. [C]

COG id: COG0219

COG function: function code J; Predicted rRNA methylase (SpoU class)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.34 [C]

Molecular weight: Translated: 16999; Mature: 16867

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGFYGVAVWHPKHEVNVGTLWRSAMTYQASMLATIGSRYKPQASDTCRAHNAIPLHHY
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHH
RDIDDLIAHLPYGCPLVGVELDARAVSLNEFTHPVRALYLLGAEDHGLPAAVLDRCHHVV
CCHHHHHHHCCCCCEEEEEEECCEEEEHHHHHCHHHEEEEECCCCCCCCHHHHHHCHHEE
QIPSPSPWSLNVSVAGSLVMHDRWSKTGGLRAVNA
ECCCCCCCEEEEEECCEEEEECCCCCCCCEEEECC
>Mature Secondary Structure 
TTGFYGVAVWHPKHEVNVGTLWRSAMTYQASMLATIGSRYKPQASDTCRAHNAIPLHHY
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHH
RDIDDLIAHLPYGCPLVGVELDARAVSLNEFTHPVRALYLLGAEDHGLPAAVLDRCHHVV
CCHHHHHHHCCCCCEEEEEEECCEEEEHHHHHCHHHEEEEECCCCCCCCHHHHHHCHHEE
QIPSPSPWSLNVSVAGSLVMHDRWSKTGGLRAVNA
ECCCCCCCEEEEEECCEEEEECCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; tRNATyr [C]

Specific reaction: S-Adenosyl-L-methionine + tRNATyr = S-adenosyl-L-homocysteine + tRNATyr Containing 2'-O-methylguanosine [C]

General reaction: Methyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA