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The map label for this gene is dapB

Identifier: 54025851

GI number: 54025851

Start: 4094203

End: 4094949

Strand: Reverse

Name: dapB

Synonym: nfa38810

Alternate gene names: 54025851

Gene position: 4094949-4094203 (Counterclockwise)

Preceding gene: 54025852

Following gene: 54025850

Centisome position: 68.01

GC content: 72.16

Gene sequence:

>747_bases
GTGACCATTCGGGTCGGAGTGCTGGGAGCACGCGGGAAAGTCGGCCAGGCGATCTGCGCGGCGGTGCGGGCGGCGGACGA
CCTGGAGCTGGTCGCCGAGGTCGACAAGGGCGACGCCCTGGAGACCTTCACCGAGACGGGCACCGAGGTCGTCGTCGACT
TCACCCACCCCGACGTGGTGATGGGCAACCTGAAGTTCCTGGTCGAGCACGGCATCCACGCCGTCGTCGGCACCACCGGC
TTCGACGCCGCGCGACTGGACGAGGTGCGCGGCTGGCTGGCGGCGAGCCCCGCGACCGGTGTGCTGATCGCGCCGAACTT
CGCCATCGGCGCGGTGCTGTCGATGCGGTTCGCCGAGCAGGCCGCCCGGTTCTTCGAGTCGGTCGAGGTCATCGAACTGC
ATCACCCGAACAAGGCCGACGCCCCCTCCGGCACCGCCTACCGCACCGCCGGGCTCATCGCCGAGGCCAGGAACCGCGCC
GGAGTCGGCCGCAGCCCCGACGCCACCAGCACCGAACTCGACGGCGCCCGCGGCGCCGACGTCGACGGGGTGCGGGTGCA
CTCGGTGCGGCTGGCCGGGCTGGTCGCCCACCAGGAGGTGCTGTTCGGCACCCAGGGGGAGACGCTGACCATCCGCCACG
ACTCCATCGACCGGTCCTCCTTCGCGCCCGGCGTGCTGCTCGGCGTGCGCGAGATCGGCAAGCGGCCCGGGCTCACCGTC
GGACTCGACCCGTTCCTGGACCTGTGA

Upstream 100 bases:

>100_bases
GCTGCGCCAGGTGATCGTCTTCGACTGAGGACGGGGCCGCGCCGGCCCGCGGGCGCCGCTCGATAGGCTTGCCACCACAT
CGGCGAGACGAGGAGGTGCG

Downstream 100 bases:

>100_bases
GCACCGCGGCCGGACCCGGCGACGGCCGCGCGGTGGCCCGCATCGTCGTGTTCATCGCGGCGCTGGTGCTGGTGCTCGGC
TTCTACTTCCTGTGGCTCGG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTIRVGVLGARGKVGQAICAAVRAADDLELVAEVDKGDALETFTETGTEVVVDFTHPDVVMGNLKFLVEHGIHAVVGTTG
FDAARLDEVRGWLAASPATGVLIAPNFAIGAVLSMRFAEQAARFFESVEVIELHHPNKADAPSGTAYRTAGLIAEARNRA
GVGRSPDATSTELDGARGADVDGVRVHSVRLAGLVAHQEVLFGTQGETLTIRHDSIDRSSFAPGVLLGVREIGKRPGLTV
GLDPFLDL

Sequences:

>Translated_248_residues
MTIRVGVLGARGKVGQAICAAVRAADDLELVAEVDKGDALETFTETGTEVVVDFTHPDVVMGNLKFLVEHGIHAVVGTTG
FDAARLDEVRGWLAASPATGVLIAPNFAIGAVLSMRFAEQAARFFESVEVIELHHPNKADAPSGTAYRTAGLIAEARNRA
GVGRSPDATSTELDGARGADVDGVRVHSVRLAGLVAHQEVLFGTQGETLTIRHDSIDRSSFAPGVLLGVREIGKRPGLTV
GLDPFLDL
>Mature_247_residues
TIRVGVLGARGKVGQAICAAVRAADDLELVAEVDKGDALETFTETGTEVVVDFTHPDVVMGNLKFLVEHGIHAVVGTTGF
DAARLDEVRGWLAASPATGVLIAPNFAIGAVLSMRFAEQAARFFESVEVIELHHPNKADAPSGTAYRTAGLIAEARNRAG
VGRSPDATSTELDGARGADVDGVRVHSVRLAGLVAHQEVLFGTQGETLTIRHDSIDRSSFAPGVLLGVREIGKRPGLTVG
LDPFLDL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=264, Percent_Identity=29.9242424242424, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_NOCFA (Q5YSW2)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_120093.1
- ProteinModelPortal:   Q5YSW2
- SMR:   Q5YSW2
- GeneID:   3109807
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa38810
- NMPDR:   fig|247156.1.peg.3777
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- BioCyc:   NFAR247156:NFA38810-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 26040; Mature: 25909

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRVGVLGARGKVGQAICAAVRAADDLELVAEVDKGDALETFTETGTEVVVDFTHPDVV
CEEEEEEEECCCCHHHHHHHHHHCCCCHHEEEECCCCCHHHHHHCCCCEEEEEECCCCEE
MGNLKFLVEHGIHAVVGTTGFDAARLDEVRGWLAASPATGVLIAPNFAIGAVLSMRFAEQ
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHEECCCCCCEEECCCHHHHHHHHHHHHHH
AARFFESVEVIELHHPNKADAPSGTAYRTAGLIAEARNRAGVGRSPDATSTELDGARGAD
HHHHHHCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
VDGVRVHSVRLAGLVAHQEVLFGTQGETLTIRHDSIDRSSFAPGVLLGVREIGKRPGLTV
CCCEEEEEEEEHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEE
GLDPFLDL
CCCHHCCC
>Mature Secondary Structure 
TIRVGVLGARGKVGQAICAAVRAADDLELVAEVDKGDALETFTETGTEVVVDFTHPDVV
EEEEEEEECCCCHHHHHHHHHHCCCCHHEEEECCCCCHHHHHHCCCCEEEEEECCCCEE
MGNLKFLVEHGIHAVVGTTGFDAARLDEVRGWLAASPATGVLIAPNFAIGAVLSMRFAEQ
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHEECCCCCCEEECCCHHHHHHHHHHHHHH
AARFFESVEVIELHHPNKADAPSGTAYRTAGLIAEARNRAGVGRSPDATSTELDGARGAD
HHHHHHCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
VDGVRVHSVRLAGLVAHQEVLFGTQGETLTIRHDSIDRSSFAPGVLLGVREIGKRPGLTV
CCCEEEEEEEEHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEE
GLDPFLDL
CCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA