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The map label for this gene is pgsA2 [H]

Identifier: 54025828

GI number: 54025828

Start: 4073444

End: 4074112

Strand: Reverse

Name: pgsA2 [H]

Synonym: nfa38580

Alternate gene names: 54025828

Gene position: 4074112-4073444 (Counterclockwise)

Preceding gene: 54025831

Following gene: 54025827

Centisome position: 67.66

GC content: 71.0

Gene sequence:

>669_bases
GTGATCGAGGGCCGTCACGCCGATACGGCGATGTCGCGCCCCGGCCCTGATCAGGTGCCGGGGCGCCCCGGTTTCGTCGC
GGCTCCCTCGGAAGCGGCGGTGCCCGTCCTCAACGTCGCGAACGTGCTGACGATGGCCCGCATCGCGATCGTTCCGGTGT
TCGTGCTCGCGCTGTTCGCCGGTGGCGGGCACGACACGGGCTGGCGGATCGGTGCCGCCGCGCTGTTCGGCCTGGCCGCC
ATCACCGACCGCTTCGATGGGCAACTGGCCCGCAAATACGGGCTGGTCACCGACTTCGGCAAGCTGGCCGACCCCATCGC
GGACAAGGCCCTCATCGGCGCGTCGCTGATCGGCCTGTCGGCGCTCGGTGACCTGCCGTGGTGGATCACGCTGGTGATCA
TCGCCAGAGAACTCGGGGTCACGCTGCTGCGGCTGGTGGTGGTGCGGCGCGGGGTGATCCCGGCCGGCCGCGGCGGCAAG
CTGAAGACGCTGGTGCAGTCGGTCGCCATCGCCGTGCTGCTGCTGCCCCTCGCGGGCGGATTCGCGACGGCGGGAATGAT
CCTGATGTACGTGGCGCTGGTGCTGACGGTGGTGACCGGACTCGACTACGTGGGCCAGGCGGCGCGGGTGTGGTTCGCCG
GTGGCACGCATCGGACCCGCGGCGCATGA

Upstream 100 bases:

>100_bases
GTGTGCCGCACATCCTGTCGTTCCGCTCACCGCATCGCGCCGGGGCAGCGCAACCGCAGGCTGTGACGCCGCGGGCGTCG
CGCGGGAGCGAGGTTTCCGC

Downstream 100 bases:

>100_bases
GCGGGGCGGATGTGTCCGAACCGGCGGCCGTGCCCGACCCGCTCGCGGGGGACGCCCCGGTCGCCGAGCTGGTACGGGCC
TTGCGGGCCGCGGGCCAGAC

Product: putative phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIEGRHADTAMSRPGPDQVPGRPGFVAAPSEAAVPVLNVANVLTMARIAIVPVFVLALFAGGGHDTGWRIGAAALFGLAA
ITDRFDGQLARKYGLVTDFGKLADPIADKALIGASLIGLSALGDLPWWITLVIIARELGVTLLRLVVVRRGVIPAGRGGK
LKTLVQSVAIAVLLLPLAGGFATAGMILMYVALVLTVVTGLDYVGQAARVWFAGGTHRTRGA

Sequences:

>Translated_222_residues
MIEGRHADTAMSRPGPDQVPGRPGFVAAPSEAAVPVLNVANVLTMARIAIVPVFVLALFAGGGHDTGWRIGAAALFGLAA
ITDRFDGQLARKYGLVTDFGKLADPIADKALIGASLIGLSALGDLPWWITLVIIARELGVTLLRLVVVRRGVIPAGRGGK
LKTLVQSVAIAVLLLPLAGGFATAGMILMYVALVLTVVTGLDYVGQAARVWFAGGTHRTRGA
>Mature_222_residues
MIEGRHADTAMSRPGPDQVPGRPGFVAAPSEAAVPVLNVANVLTMARIAIVPVFVLALFAGGGHDTGWRIGAAALFGLAA
ITDRFDGQLARKYGLVTDFGKLADPIADKALIGASLIGLSALGDLPWWITLVIIARELGVTLLRLVVVRRGVIPAGRGGK
LKTLVQSVAIAVLLLPLAGGFATAGMILMYVALVLTVVTGLDYVGQAARVWFAGGTHRTRGA

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=178, Percent_Identity=36.5168539325843, Blast_Score=95, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22994; Mature: 22994

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEGRHADTAMSRPGPDQVPGRPGFVAAPSEAAVPVLNVANVLTMARIAIVPVFVLALFA
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GGGHDTGWRIGAAALFGLAAITDRFDGQLARKYGLVTDFGKLADPIADKALIGASLIGLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGDLPWWITLVIIARELGVTLLRLVVVRRGVIPAGRGGKLKTLVQSVAIAVLLLPLAGG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCH
FATAGMILMYVALVLTVVTGLDYVGQAARVWFAGGTHRTRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCC
>Mature Secondary Structure
MIEGRHADTAMSRPGPDQVPGRPGFVAAPSEAAVPVLNVANVLTMARIAIVPVFVLALFA
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GGGHDTGWRIGAAALFGLAAITDRFDGQLARKYGLVTDFGKLADPIADKALIGASLIGLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGDLPWWITLVIIARELGVTLLRLVVVRRGVIPAGRGGKLKTLVQSVAIAVLLLPLAGG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCH
FATAGMILMYVALVLTVVTGLDYVGQAARVWFAGGTHRTRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]